TGF-β-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation

EMBO Journal

Volumn 20, Issue 9, 2001, Pages 2254-2272

  Alliston, Tamara ^a   Choy, Lisa ^a   Ducy, Patricia ^b   Karsenty, Gérard ^b   Derynck, Rik ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

CBFA1; Osteoblast differentiation; Smad3; TGF

Indexed keywords

SMAD PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RUNX2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE REPRESSION; MOUSE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DNA; DNA-BINDING PROTEINS; EPITHELIAL CELLS; GENE EXPRESSION; HUMANS; MESODERM; MICE; NEOPLASM PROTEINS; OSTEOBLASTS; OSTEOCALCIN; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RATS; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA;

EID: 0035341209     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.9.2254     Document Type: Article

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