Osteoblastic responses to TGF-β during bone remodeling

Molecular Biology of the Cell

Volumn 9, Issue 7, 1998, Pages 1903-1918

  Erlebacher, Adrian ^a   Filvaroff, Ellen H ^a   Ye, Jian Qin ^a,b   Derynck, Rik ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MATRIX; BONE REMODELING; CELL DIFFERENTIATION; CONTROLLED STUDY; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOLYSIS; PRIORITY JOURNAL; REGULATORY MECHANISM; TRANSGENIC MOUSE;

ANIMALIA; MAMMALIA; MUS MUSCULUS;

EID: 0031846157     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.9.7.1903     Document Type: Article

References (41)

1. Aarden, E.M., Burger, E.H., and Nijweide, P.J. (1994). Function of osteocytes in bone. J. Cell. Biochem. 55, 287-299.
2. Baker, A.R., Hollingshead, P.G., Pitts, M.S., Hansen, S., Taylor, R., and Stewart, T.A. (1992). Osteoblast-specific expression of growth a hormone stimulates bone growth in transgenic mice. Mol. Cell. Biol. 12, 5541-5547.
3. Bonadio, J., Jepsen, K.J., Mansoura, M.K., Jaenisch, R., Kuhn, J.L., and Goldstein, S.A. (1993). A murine skeletal adaptation that significantly increases cortical bone mechanical properties. Implications for human skeletal fragility. J. Clin. Invest 92, 1697-1705.
4. Bonewald, L.F., and Dallas, S.L. (1994). Role of active and latent transforming growth factor β in bone formation. J. Cell Biochem. 55, 350-357.
5. Boyde, A. (1972). Scanning electron microscope studies of bone. In Biochemistry and Physiology of Bone, vol. 1, ed. G. H. Bourne, New York: Academic Press, 259-310.
6. Bronckers, A.L., Gay, S., Dimuzio, M.T., and Butler, W.T. (1985). Immunolocalization of γ-carboxyglutamic acid containing proteins in developing rat bones. Collagen Relat. Res. 5, 273-281.
7. Centrella, M., Horowitz, M.C., Wozney, J.M., and McCarthy, T.L. (1994). Transforming growth factor-β gene family members and bone. Endocr. Rev. 15, 27-39.
8. Chen, R.H., Ebner, R., and Derynck, R. (1993). Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-β activities. Science 260, 1335-1338.
9. Derynck, R., and Feng, X.-H. (1997). TGF-β receptor signaling. Biochim Biophys. Acta Rev. Cancer 1333, F105-F150.
10. Ducy, P., Zhang, R., Geoffry, V., Ridall, A.L., and Karsenty, G. (1997). Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89, 747-754.
11. Erlebacher, A., and Derynck, R. (1996). Increased expression of TGF-β2 in osteoblasts results in an osteoporsis-like phenotype. J. Cell Biol. 132, 195-210.
12. Grigoriadis, A.E., Wang, Z.Q., Cecchini, M.G., Hofstetter, W., Felix, R., Fleisch, H.A., and Wagner, E.F. (1994). c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science 266, 443-448.
13. Groot, C.G., Danes, J.K., Blok, J., Hoogendijk, A., and Hauschka, P.V. (1986). Light and electron microscopic demonstration of osteocalcin antigenicity in embryonic and adult rat bone. Bone 7, 379-385.
14. Hock, J.M., and Gera, I. (1992). Effects of continuous and intermittent administration and inhibition of resorption on the anabolic response of bone to parathyroid hormone. J. Bone Miner. Res. 7, 65-72.
15. Johnson, R.S., Spiegelman, B.M., and Papaioannou, V. (1992). Pleiotropic effects of a null mutation in the c-fos proto-oncogene. Cell 71, 577-586.
16. Joyce, M.E., Roberts, A.B., Sporn, M.B., and Bolander, M.E. (1990). Transforming growth factor-β and the initiation of chondrogenesis and osteogenesis in the rat femur. J. Cell Biol. 110, 2195-2207.
17. Kimmel, D.B., and Jee, W.S. (1980). A quantitative histological analysis of the growing long bone metaphysis. Calcif. Tissue Int. 32, 113-122.
18. Komori, T. et al. (1997). Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89, 755-764.
19. Malluche, H.H., and Faugere, M. (1990). Bone biopsies: histology and histomorphometry of bone. In Metabolic Bone Disease and Clinically Related Disorders, ed. L.V. Avioli and S.M. Krane, Philadelphia: W.B. Saunders, 283-328.
20. Meyer, R.A., Jr., Tenenhouse, H.S., Meyer, M.H., and Klugerman, A.H. (1989). The renal phosphate transport defect in normal mice parabiosed to X-linked hypophosphatemic mice persists after parathyroidectomy. J. Bone Miner. Res. 4, 523-532.
21. Mullender, M.G., van der Meer, D.D., Huiskes, R., and Lips, P. (1996). Osteocyte density changes in aging and osteoporosis. Bone 18, 109-113.
22. Noda, M., and Camilliere, J.J. (1989). In vivo stimulation of bone formation by transforming growth factor-β. Endocrinology 124, 2991-2994.
23. Oreffo, R.O., Mundy, G.R., Seyedin, S.M., and Bonewald, L.F. (1989). Activation of the bone-derived latent TGF-β complex by isolated osteoclasts. Biochem. Biophys. Res. Commun. 158, 817-823.
24. Otto, F. et al. (1997). Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 89, 765-771.
25. Oursler, M.J. (1994). Osteoclast synthesis and secretion and activation of latent transforming growth factor β. J. Bone Miner. Res. 9, 443-452.
26. Packard, D.S., Jr., Menzies, R.A., and Skalko, R.G. (1973). Incorporation of thymidine and its analogue, bromodeoxyuridine, into embryos and maternal tissues of the mouse. Differentiation 1, 397-404.
27. Parfitt, A.M. (1994). Osteonal and hemi-osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone. J. Cell. Biochem. 55, 273-286.
28. Parfitt, A.M., Drezner, M.K., Glorieux, F.H., Kanis, J.A., Malluche, H., Meunier, P.J., Ott, S.M., and Recker, R.R. (1987). Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J. Bone Miner. Res. 2, 595-610.
29. Pelton, R.W., Saxena, B., Jones, M., Moses, H.L., and Gold, L.I. (1991). Immunohistochemical localization of TGF-β1, TGF-β2, and TGF-β3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. J. Cell. Biol. 115, 1091-1105.
30. Pereira, R.F., Hume, E.L., Halford, K.W., and Prockop, D.J. (1995). Bone fragility in transgenic mice expressing a mutated gene for type I procollagen (COL1A1) parallels the age-dependent phenotype of human osteogenesis imperfecta. J. Bone Miner. Res. 20, 1837-1843.
31. Pfeilschifter, J., and Mundy, G.R. (1987). Modulation of type β transforming growth factor activity in bone cultures by osteotropic hormones. Proc. Natl. Acad. Sci. USA 84, 2024-2028.
32. Robey, P.G., Young, M.F., Flanders, K.C., Roche, N.S., Kondaiah, P., Reddi, A.H., Termine, J.D., Sporn, M.B., and Roberts, A.B. (1987). Osteoblasts synthesize and respond to transforming growth factor-type β (TGF-β) in vitro. J. Cell Biol. 105, 457-463.
33. Rodan, G.A., and Fleisch, H.A. (1996). Bisphosphonates: mechanisms of action. J. Clin. Invest. 97, 2692-2696.
34. Sandberg, M., Vuorio, T., Hirvonen, H., Alitalo, K., and Vuorio, E. (1988). Enhanced expression of TGF-β and c-fos mRNAs in the growth plates of developing human long bones. Development 102, 461-470.
35. Seyedin, S.M., Thomas, T.C., Thompson, A.Y., Rosen, D.M., and Piez, K.A. (1985). Purification and characterization of two cartilage-inducing factors from bovine demineralized bone. Proc. Natl. Acad. Sci. USA 82, 2267-2271.
36. Sissons, H.A., and O'Connor, P. (1977). Quantitative histology of osteocyte lacunae in normal human cortical bone. Calcif. Tissue Res. 22, 530-533.
37. Taylor, J.R. (1997). An Introduction to Error Analysis: The Study of Uncertainties in Physical Measurements, 2nd ed. Sausalito, CA: University Science Books.
38. Uzawa, T., Hori, M., Ejiri, S., and Ozawa, H. (1995). Comparison of the effects of intermittent and continuous administration of human parathyroid hormone(1-34) on rat bone. Bone 16, 477-484.
39. Wang, Z.Q., Ovitt, C., Grigoriadis, A.E., Mohle-Steinlein, U., Ruther, U., and Wagner, E.F. (1992). Bone and haematopoietic defects in mice lacking c-fos. Nature 360, 741-745.
40. Whyte, M.P. (1996). Osteogenesis imperfecta. In Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, ed. M.J. Favus, Philadelphia: Lippincott-Raven, 382-384.
41. Young, R.W. (1962). Cell proliferation and specialization during endochondral osteogenesis in young rats. J. Cell Biol. 14, 357-370.