Exploiting protein flexibility to predict the location of allosteric sites

BMC Bioinformatics

Volumn 13, Issue 1, 2012, Pages

  Panjkovich, Alejandro ^a   Daura, Xavier ^a,b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC MECHANISMS; ALLOSTERIC MODULATION; ALLOSTERIC PROPERTIES; ALLOSTERIC PROTEINS; ALLOSTERIC SITE; ALLOSTERY; COARSE-GRAINED; COMPUTATIONAL APPROACH; CURRENT ANALYSIS; DRUG DISCOVERY; LIGAND BINDING; NON-REDUNDANT; NORMAL MODE ANALYSIS; NORMAL MODES; ON DYNAMICS; POSITIVE PREDICTIVE VALUES; PROTEIN ACTIVITY; PROTEIN DYNAMICS; PROTEIN FLEXIBILITY; STRUCTURAL INFORMATION; THERAPEUTIC POTENTIALS; THERAPEUTIC SOLUTIONS;

BINDING SITES; COMPUTATIONAL METHODS; FORECASTING; LIGANDS; QUERY PROCESSING;

PROTEINS;

HARNESS;

LIGAND; PROTEIN;

ALLOSTERISM; ARTICLE; BINDING SITE; BIOLOGY; CHEMISTRY; DRUG DEVELOPMENT; ENZYME ACTIVE SITE; HUMAN; METHODOLOGY; PLIABILITY; PROTEIN CONFORMATION; SEQUENCE ANALYSIS;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; CATALYTIC DOMAIN; COMPUTATIONAL BIOLOGY; DRUG DISCOVERY; HUMANS; LIGANDS; PLIABILITY; PROTEIN CONFORMATION; PROTEINS; SEQUENCE ANALYSIS, PROTEIN;

MLCS; MLOWN;

EID: 84867744642     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-13-273     Document Type: Article

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