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Volumn 7, Issue 11, 2012, Pages 1297-1313

Mechanisms of infection by the human fungal pathogen Cryptococcus neoformans

Author keywords

blood brain barrier; brain; cryptococcal meningoencephalitis; Cryptococcus neoformans; dissemination; infection; macrophages

Indexed keywords

MELANIN; PHOSPHOLIPASE; PROTEINASE; UREASE;

EID: 84867719522     PISSN: 17460913     EISSN: 17460921     Source Type: Journal    
DOI: 10.2217/fmb.12.102     Document Type: Review
Times cited : (67)

References (177)
  • 1
    • 62349130224 scopus 로고    scopus 로고
    • Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS
    • Park BJ, Wannemuehler KA, Marston BJ, Govender N, Pappas PG, Chiller TM. Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS. AIDS 23(4), 525-530 (2009
    • (2009) AIDS , vol.23 , Issue.4 , pp. 525-530
    • Park, B.J.1    Wannemuehler, K.A.2    Marston, B.J.3    Govender, N.4    Pappas, P.G.5    Chiller, T.M.6
  • 2
    • 77955743248 scopus 로고    scopus 로고
    • Cost-effectiveness of serum cryptococcal antigen screening to prevent deaths among HIV-infected persons with a CD4+ cell count < or = 100 cells/microL who start HIV therapy in resource-limited settings
    • Meya DB, Manabe YC, Castelnuovo B et al. Cost-effectiveness of serum cryptococcal antigen screening to prevent deaths among HIV-infected persons with a CD4+ cell count < or = 100 cells/microL who start HIV therapy in resource-limited settings. Clin. Infect. Dis. 51(4), 448-455 (2010).
    • (2010) Clin. Infect. Dis , vol.51 , Issue.4 , pp. 448-455
    • Meya, D.B.1    Manabe, Y.C.2    Castelnuovo, B.3
  • 3
    • 43949142136 scopus 로고    scopus 로고
    • Outcomes of cryptococcal meningitis in Uganda before and after the availability of highly active antiretroviral therapy
    • Kambugu A, Meya DB, Rhein J et al. Outcomes of cryptococcal meningitis in Uganda before and after the availability of highly active antiretroviral therapy. Clin. Infect. Dis. 46(11), 1694-1701 (2008).
    • (2008) Clin. Infect. Dis , vol.46 , Issue.11 , pp. 1694-1701
    • Kambugu, A.1    Meya, D.B.2    Rhein, J.3
  • 4
    • 67651094203 scopus 로고    scopus 로고
    • High ongoing burden of cryptococcal disease in Africa despite antiretroviral roll out
    • Jarvis JN, Boulle A, Loyse A et al. High ongoing burden of cryptococcal disease in Africa despite antiretroviral roll out. AIDS 23(9), 1182-1183 (2009).
    • (2009) AIDS , vol.23 , Issue.9 , pp. 1182-1183
    • Jarvis, J.N.1    Boulle, A.2    Loyse, A.3
  • 5
    • 0033801252 scopus 로고    scopus 로고
    • Practice guidelines for the management of cryptococcal disease
    • Infectious Diseases Society of America
    • Saag MS, Graybill RJ, Larsen RA et al. Practice guidelines for the management of cryptococcal disease. Infectious Diseases Society of America. Clin. Infect. Dis. 30(4), 710-718 (2000).
    • (2000) Clin. Infect. Dis , vol.30 , Issue.4 , pp. 710-718
    • Saag, M.S.1    Graybill, R.J.2    Larsen, R.A.3
  • 6
    • 34250837370 scopus 로고    scopus 로고
    • Management of cryptococcal meningitis in AIDS: The need for specific studies in developing countries
    • Lortholary O. Management of cryptococcal meningitis in AIDS: The need for specific studies in developing countries. Clin. Infect. Dis. 45(1), 81-83 (2007).
    • (2007) Clin. Infect. Dis , vol.45 , Issue.1 , pp. 81-83
    • Lortholary, O.1
  • 7
    • 77954082225 scopus 로고    scopus 로고
    • Cryptococcus gattii outbreak expands into the northwestern United States with fatal consequences
    • Byrnes EJ, Heitman J. Cryptococcus gattii outbreak expands into the northwestern United States with fatal consequences. F1000 Biol. Rep. 1, 62 (2009).
    • (2009) F1000 Biol. Rep , vol.1 , pp. 62
    • Byrnes, E.J.1    Heitman, J.2
  • 8
    • 77954325313 scopus 로고    scopus 로고
    • A prospective descriptive study of cryptococcal meningitis in HIV uninfected patients in Vietnam - high prevalence of Cryptococcus neoformans var grubii in the absence of underlying disease
    • Chau TT, Mai NH, Phu NH et al. A prospective descriptive study of cryptococcal meningitis in HIV uninfected patients in Vietnam - high prevalence of Cryptococcus neoformans var grubii in the absence of underlying disease. BMC Infect. Dis. 10, 199 (2010).
    • (2010) BMC Infect. Dis , vol.10 , Issue.199
    • Chau, T.T.1    Mai, N.H.2    Phu, N.H.3
  • 9
    • 77952506364 scopus 로고    scopus 로고
    • Cryptococcal meningitis in non-hiv-infected patients in a chinese tertiary care hospital 1997-2007
    • Zhu LP, Wu JQ, Xu B, Ou XT, Zhang QQ, Weng XH. Cryptococcal meningitis in non-HIV-infected patients in a Chinese tertiary care hospital, 1997-2007. Med. Mycol. 48(4), 570-579 (2010).
    • (2010) Med. Mycol , vol.48 , Issue.4 , pp. 570-579
    • Zhu, L.P.1    Wu, J.Q.2    Xu, B.3    Ou, X.T.4    Zhang, Q.Q.5    Weng, X.H.6
  • 10
    • 39449095504 scopus 로고    scopus 로고
    • Pulmonary cryptococcosis in solid organ transplant recipients:Clinical relevance of serum cryptococcal antigen
    • Singh N, Alexander BD, Lortholary O et al. Pulmonary cryptococcosis in solid organ transplant recipients:Clinical relevance of serum cryptococcal antigen. Clin. Infect. Dis. 46(2), e12-e18 (2008).
    • (2008) Clin. Infect. Dis , vol.46 , Issue.2
    • Singh, N.1    Alexander, B.D.2    Lortholary, O.3
  • 11
    • 72949092121 scopus 로고    scopus 로고
    • AST infectious diseases community of practice:Cryptococcosis in solid organ transplant recipients
    • Singh N, Forrest G. AST infectious diseases community of practice:Cryptococcosis in solid organ transplant recipients. Am. J. Transplant. 9(Suppl. 4), S192-S198(2009).
    • (2009) Am. J. Transplant , vol.9 , Issue.SUPPL. 4
    • Singh, N.1    Forrest, G.2
  • 12
    • 84863487718 scopus 로고    scopus 로고
    • Paradoxical roles of alveolar macrophages in the host response to Cryptococcus neoformans
    • McQuiston TJ, Williamson PR. Paradoxical roles of alveolar macrophages in the host response to Cryptococcus neoformans. J. Infect. Chemother. 18(1), 1-9 (2012).
    • (2012) J. Infect. Chemother , vol.18 , Issue.1 , pp. 1-9
    • McQuiston, T.J.1    Williamson, P.R.2
  • 13
    • 73949123165 scopus 로고    scopus 로고
    • Projecting global occurrence of cryptococcus gattii
    • Springer DJ, Chaturvedi V. Projecting global occurrence of Cryptococcus gattii. Emerg. Infect. Dis. 16(1), 14-20 (2010).
    • (2010) Emerg. Infect. Dis , vol.16 , Issue.1 , pp. 14-20
    • Springer, D.J.1    Chaturvedi, V.2
  • 14
    • 0027959574 scopus 로고
    • One hundred years of cryptococcosis medical mycology in the 19th century in greifswald
    • Knoke M, Schwesinger G. One hundred years of cryptococcosis. Medical mycology in the 19th century in Greifswald. Mycoses 37(SUPPL1, S28-S33 (1994).
    • (1994) Mycoses , vol.37 , Issue.SUPPL. 1
    • Knoke, M.1    Schwesinger, G.2
  • 15
    • 0028786641 scopus 로고
    • Cryptococcosis in the era of AIDS - 100 years after the discovery of Cryptococcus neoformans
    • Mitchell TG, Perfect Jr. Cryptococcosis in the era of AIDS - 100 years after the discovery of Cryptococcus neoformans. Clin. Microbiol. Rev. 8(4), 515-548 (1995).
    • (1995) Clin. Microbiol. Rev , vol.8 , Issue.4 , pp. 515-548
    • Mitchell, T.G.1    Perfect, J.R.2
  • 16
    • 0033058352 scopus 로고    scopus 로고
    • Cryptococcus neoformans var grubii: Separate varietal status for Cryptococcus neoformans serotype A isolates
    • Franzot SP, Salkin IF, Casadevall A. Cryptococcus neoformans var. grubii: Separate varietal status for Cryptococcus neoformans serotype A isolates. J. Clin. Microbiol. 37(3), 838-840 (1999).
    • (1999) J. Clin. Microbiol , vol.37 , Issue.3 , pp. 838-840
    • Franzot, S.P.1    Salkin, I.F.2    Casadevall, A.3
  • 17
    • 0030933623 scopus 로고    scopus 로고
    • Molecular typing of Cryptococcus neoformans: Taxonomic and epidemiological aspects
    • Boekhout T, van Belkum A, Leenders AC et al. Molecular typing of Cryptococcus neoformans: Taxonomic and epidemiological aspects. Int. J. Syst. Bacteriol. 47(2), 432-442 (1997).
    • (1997) Int. J. Syst. Bacteriol , vol.47 , Issue.2 , pp. 432-442
    • Boekhout, T.1    Van Belkum, A.2    Leenders, A.C.3
  • 18
    • 0036881280 scopus 로고    scopus 로고
    • Proposal to conserve the name cryptococcus gattii against C. hondurianus and C bacillisporus (basidiomycota, hymenomycetes, tremellomycetidae
    • Kwon-Chung KJ, Boekhout T, Fell JW, Diaz M. Proposal to conserve the name Cryptococcus gattii against C. hondurianus and C. bacillisporus (Basidiomycota, Hymenomycetes, Tremellomycetidae). Taxon 51(4), 804-806 (2002).
    • (2002) Taxon , vol.51 , Issue.4 , pp. 804-806
    • Kwon-Chung, K.J.1    Boekhout, T.2    Fell, J.W.3    Diaz, M.4
  • 19
    • 0031927833 scopus 로고    scopus 로고
    • Genetic relationship between Cryptococcus neoformans var neoformans strains of serotypes A and D
    • Franzot SP, Fries BC, Cleare W, Casadevall A. Genetic relationship between Cryptococcus neoformans var. neoformans strains of serotypes A and D. J. Clin. Microbiol. 36(8), 2200-2204 (1998).
    • (1998) J. Clin. Microbiol , vol.36 , Issue.8 , pp. 2200-2204
    • Franzot, S.P.1    Fries, B.C.2    Cleare, W.3    Casadevall, A.4
  • 20
    • 67649222249 scopus 로고    scopus 로고
    • Genetic diversity of the Cryptococcus species complex suggests that Cryptococcus gattii deserves to have varieties
    • Ngamskulrungroj P, Gilgado F, Faganello J et al. Genetic diversity of the Cryptococcus species complex suggests that Cryptococcus gattii deserves to have varieties. Plos One 4(6), e5862 (2009).
    • (2009) Plos One , vol.4 , Issue.6
    • Ngamskulrungroj, P.1    Gilgado, F.2    Faganello, J.3
  • 21
    • 79955766878 scopus 로고    scopus 로고
    • Low diversity Cryptococcus neoformans variety grubii multilocus sequence types from Thailand are consistent with an ancestral African origin
    • Simwami SP, Khayhan K, Henk DA et al. Low diversity Cryptococcus neoformans variety grubii multilocus sequence types from Thailand are consistent with an ancestral African origin. Plos Pathog. 7(4), e1001343 (2011).
    • (2011) Plos Pathog , vol.7 , Issue.4
    • Simwami, S.P.1    Khayhan, K.2    Henk, D.A.3
  • 22
    • 33646193463 scopus 로고    scopus 로고
    • Multilocus sequence typing reveals three genetic subpopulations of cryptococcus neoformans var. grubii (serotype A), including a unique population in botswana
    • Litvintseva AP, Thakur R, Vilgalys R, Mitchell TG. Multilocus sequence typing reveals three genetic subpopulations of Cryptococcus neoformans var. grubii (serotype A), including a unique population in Botswana. Genetics 172(4), 2223-2238 (2006).
    • (2006) Genetics , vol.172 , Issue.4 , pp. 2223-2238
    • Litvintseva, A.P.1    Thakur, R.2    Vilgalys, R.3    Mitchell, T.G.4
  • 24
    • 79955912805 scopus 로고    scopus 로고
    • Evidence that the human pathogenic fungus Cryptococcus neoformans var. grubii may have evolved in Africa
    • Litvintseva AP, Carbone I, Rossouw J, Thakur R, Govender NP, Mitchell TG. Evidence that the human pathogenic fungus Cryptococcus neoformans var. grubii may have evolved in Africa. Plos One 6(5), e19688 (2011).
    • (2011) Plos One , vol.6 , Issue.5
    • Litvintseva, A.P.1    Carbone, I.2    Rossouw, J.3    Thakur, R.4    Govender, N.P.5    Mitchell, T.G.6
  • 25
    • 34548422823 scopus 로고    scopus 로고
    • Many globally isolated AD hybrid strains of Cryptococcus neoformans originated in Africa
    • Litvintseva AP, Lin X, Templeton I, Heitman J, Mitchell TG. Many globally isolated AD hybrid strains of Cryptococcus neoformans originated in Africa. Plos Pathog. 3(8), e114 (2007).
    • (2007) Plos Pathog , vol.3 , Issue.8
    • Litvintseva, A.P.1    Lin, X.2    Templeton, I.3    Heitman, J.4    Mitchell, T.G.5
  • 27
    • 0031923046 scopus 로고    scopus 로고
    • The historical question of acquired immunodeficiency syndrome in the 1960s in the Congo River basin area in relation to cryptococcal meningitis
    • Molez JF. The historical question of acquired immunodeficiency syndrome in the 1960s in the Congo River basin area in relation to cryptococcal meningitis. Am. J. Trop. Med. Hyg. 58(3), 273-276 (1998).
    • (1998) Am. J. Trop. Med. Hyg , vol.58 , Issue.3 , pp. 273-276
    • Molez, J.F.1
  • 28
    • 0032311182 scopus 로고    scopus 로고
    • Antibody and/or cell-mediated immunity, protective mechanisms in fungal disease: An ongoing dilemma or an unnecessary dispute
    • Casadevall A, Cassone A, Bistoni F et al. Antibody and/or cell-mediated immunity, protective mechanisms in fungal disease: An ongoing dilemma or an unnecessary dispute? Med. Mycol. 36(SUPPL1, S95-S105 (1998).
    • (1998) Med. Mycol , vol.36 , Issue.SUPPL. 1
    • Casadevall, A.1    Cassone, A.2    Bistoni, F.3
  • 29
    • 59249092390 scopus 로고    scopus 로고
    • Diploids in the Cryptococcus neoformans serotype A population homozygous for the a mating type originate via unisexual mating
    • Lin X, Patel S, Litvintseva AP, Floyd A, Mitchell TG, Heitman J. Diploids in the Cryptococcus neoformans serotype A population homozygous for the a mating type originate via unisexual mating. Plos Pathog. 5(1), e1000283 (2009).
    • (2009) Plos Pathog , vol.5 , Issue.1
    • Lin, X.1    Patel, S.2    Litvintseva, A.P.3    Floyd, A.4    Mitchell, T.G.5    Heitman, J.6
  • 31
    • 0024517520 scopus 로고
    • Cutaneous cryptococcosis
    • Hernandez AD. Cutaneous cryptococcosis. Dermatol. Clin. 7(2), 269-274 (1989).
    • (1989) Dermatol. Clin , vol.7 , Issue.2 , pp. 269-274
    • Hernandez, A.D.1
  • 32
    • 63149153443 scopus 로고    scopus 로고
    • Cryptococcal liver abscess: A case report of successful treatment with amphotericin-B and literature review
    • Liu PY, Yang Y, Shi ZY. Cryptococcal liver abscess: A case report of successful treatment with amphotericin-B and literature review. Jpn J. Infect. Dis. 62(1), 59-60 (2009).
    • (2009) Jpn J. Infect. Dis , vol.62 , Issue.1 , pp. 59-60
    • Liu, P.Y.1    Yang, Y.2    Shi, Z.Y.3
  • 34
    • 33645872106 scopus 로고    scopus 로고
    • Clinical features and high-resolution CT findings of pulmonary cryptococcosis in non-AIDS patients
    • Kishi K, Homma S, Kurosaki A, Kohno T, Motoi N, Yoshimura K. Clinical features and high-resolution CT findings of pulmonary cryptococcosis in non-AIDS patients. Respir. Med. 100(5), 807-812 (2006).
    • (2006) Respir. Med , vol.100 , Issue.5 , pp. 807-812
    • Kishi, K.1    Homma, S.2    Kurosaki, A.3    Kohno, T.4    Motoi, N.5    Yoshimura, K.6
  • 35
    • 33750289222 scopus 로고    scopus 로고
    • The biology of the Cryptococcus neoformans species complex
    • Lin X, Heitman J. The biology of the Cryptococcus neoformans species complex. Annu. Rev. Microbiol. 60, 69-105 (2006).
    • (2006) Annu. Rev. Microbiol , vol.60 , pp. 69-105
    • Lin, X.1    Heitman, J.2
  • 36
    • 84907131884 scopus 로고
    • Isolation of Cryptococcus neoformans var gattii from an Asian patient in France: Evidence for dormant infection in healthy subjects
    • Dromer F, Ronin O, Dupont B. Isolation of Cryptococcus neoformans var. gattii from an Asian patient in France: Evidence for dormant infection in healthy subjects. J. Med. Vet. Mycol. 30(5), 395-397 (1992).
    • (1992) J. Med. Vet. Mycol , vol.30 , Issue.5 , pp. 395-397
    • Dromer, F.1    Ronin, O.2    Dupont, B.3
  • 37
    • 0032867947 scopus 로고    scopus 로고
    • Epidemiological evidence for dormant Cryptococcus neoformans infection
    • Garcia-Hermoso D, Janbon G, Dromer F. Epidemiological evidence for dormant Cryptococcus neoformans infection. J. Clin. Microbiol. 37(10), 3204-3209 (1999).
    • (1999) J. Clin. Microbiol , vol.37 , Issue.10 , pp. 3204-3209
    • Garcia-Hermoso, D.1    Janbon, G.2    Dromer, F.3
  • 38
    • 0035112182 scopus 로고    scopus 로고
    • Cryptococcus neoformans induces macrophage inflammatory protein 1a (MIP-1a) and MIP-1b in human microglia: Role of specific antibody and soluble capsular polysaccharide
    • Goldman D, Song X, Kitai R, Casadevall A, Zhao ML, Lee SC. Cryptococcus neoformans induces macrophage inflammatory protein 1a (MIP-1a) and MIP-1b in human microglia: Role of specific antibody and soluble capsular polysaccharide. Infect. Immun. 69(3), 1808-1815 (2001).
    • (2001) Infect. Immun , vol.69 , Issue.3 , pp. 1808-1815
    • Goldman, D.1    Song, X.2    Kitai, R.3    Casadevall, A.4    Zhao, M.L.5    Lee, S.C.6
  • 39
    • 84863471593 scopus 로고    scopus 로고
    • The primary target organ of Cryptococcus gattii is different from that of Cryptococcus neoformans in a murine model
    • Ngamskulrungroj P, Chang Y, Sionov E, Kwon-Chung KJ. The primary target organ of Cryptococcus gattii is different from that of Cryptococcus neoformans in a murine model. mBio 3(3), e00103-12 (2012) .
    • (2012) MBIO , vol.3 , Issue.3
    • Ngamskulrungroj, P.1    Chang, Y.2    Sionov, E.3    Kwon-Chung, K.J.4
  • 41
    • 67651205627 scopus 로고    scopus 로고
    • Elucidating the pathogenesis of spores from the human fungal pathogen Cryptococcus neoformans
    • Giles SS, Dagenais TR, Botts MR, Keller NP, Hull CM. Elucidating the pathogenesis of spores from the human fungal pathogen Cryptococcus neoformans. Infect. Immun. 77(8), 3491-3500 (2009).
    • (2009) Infect. Immun , vol.77 , Issue.8 , pp. 3491-3500
    • Giles, S.S.1    Dagenais, T.R.2    Botts, M.R.3    Keller, N.P.4    Hull, C.M.5
  • 42
    • 0022529445 scopus 로고
    • In vitro killing of spores and hyphae of aspergillus fumigatus and rhizopus oryzae by rabbit neutrophil cationic peptides and bronchoalveolar macrophages
    • Levitz SM, Selsted ME, Ganz T, Lehrer RI, Diamond RD. In vitro killing of spores and hyphae of Aspergillus fumigatus and Rhizopus oryzae by rabbit neutrophil cationic peptides and bronchoalveolar macrophages. J. Infect. Dis. 154(3), 483-489 (1986).
    • (1986) J. Infect. Dis , vol.154 , Issue.3 , pp. 483-489
    • Levitz, S.M.1    Selsted, M.E.2    Ganz, T.3    Lehrer, R.I.4    Diamond, R.D.5
  • 43
    • 64749088642 scopus 로고    scopus 로고
    • Isolation and characterization of Cryptococcus neoformans spores reveal a critical role for capsule biosynthesis genes in spore biogenesis
    • Botts MR, Giles SS, Gates MA, Kozel TR, Hull CM. Isolation and characterization of Cryptococcus neoformans spores reveal a critical role for capsule biosynthesis genes in spore biogenesis. Eukaryot. Cell 8(4), 595-605 (2009).
    • (2009) Eukaryot. Cell , vol.8 , Issue.4 , pp. 595-605
    • Botts, M.R.1    Giles, S.S.2    Gates, M.A.3    Kozel, T.R.4    Hull, C.M.5
  • 44
    • 33646148472 scopus 로고    scopus 로고
    • Phospholipase B activity enhances adhesion of Cryptococcus neoformans to a human lung epithelial cell line
    • Ganendren R, Carter E, Sorrell T, Widmer F, Wright L. Phospholipase B activity enhances adhesion of Cryptococcus neoformans to a human lung epithelial cell line. Microbes Infect. 8(4), 1006-1015 (2006).
    • (2006) Microbes Infect , vol.8 , Issue.4 , pp. 1006-1015
    • Ganendren, R.1    Carter, E.2    Sorrell, T.3    Widmer, F.4    Wright, L.5
  • 46
    • 0036244434 scopus 로고    scopus 로고
    • Macrophage defences against respiratory tract infections
    • Gordon SB, Read RC. Macrophage defences against respiratory tract infections. Br. Med. Bull. 61, 45-61 (2002).
    • (2002) Br. Med. Bull , vol.61 , pp. 45-61
    • Gordon, S.B.1    Read, R.C.2
  • 47
    • 0033971042 scopus 로고    scopus 로고
    • Persistent Cryptococcus neoformans pulmonary infection in the rat is associated with intracellular parasitism, decreased inducible nitric oxide synthase expression, and altered antibody responsiveness to cryptococcal polysaccharide
    • Goldman DL, Lee SC, Mednick AJ, Montella L, Casadevall A. Persistent Cryptococcus neoformans pulmonary infection in the rat is associated with intracellular parasitism, decreased inducible nitric oxide synthase expression, and altered antibody responsiveness to cryptococcal polysaccharide. Infect. Immun. 68(2), 832-838 (2000).
    • (2000) Infect. Immun , vol.68 , Issue.2 , pp. 832-838
    • Goldman, D.L.1    Lee, S.C.2    Mednick, A.J.3    Montella, L.4    Casadevall, A.5
  • 48
    • 23844458200 scopus 로고    scopus 로고
    • An innate immune system cell is a major determinant of species-related susceptibility differences to fungal pneumonia
    • Shao X, Mednick A, Alvarez M, van Rooijen N, Casadevall A, Goldman DL. An innate immune system cell is a major determinant of species-related susceptibility differences to fungal pneumonia. J. Immunol. 175(5), 3244-3251 (2005).
    • (2005) J. Immunol , vol.175 , Issue.5 , pp. 3244-3251
    • Shao, X.1    Mednick, A.2    Alvarez, M.3    Van Rooijen, N.4    Casadevall, A.5    Goldman, D.L.6
  • 49
    • 34848905334 scopus 로고    scopus 로고
    • Depletion of alveolar macrophages decreases the dissemination of a glucosylceramidedeficient mutant of Cryptococcus neoformans in immunodeficient mice
    • Kechichian TB, Shea J, Del Poeta M. Depletion of alveolar macrophages decreases the dissemination of a glucosylceramidedeficient mutant of Cryptococcus neoformans in immunodeficient mice. Infect. Immun. 75(10), 4792-4798 (2007).
    • (2007) Infect. Immun , vol.75 , Issue.10 , pp. 4792-4798
    • Kechichian, T.B.1    Shea, J.2    Del Poeta, M.3
  • 50
    • 0029094291 scopus 로고
    • Pulmonary cryptococcosis: Localized and disseminated infections in 27 patients with AIDS
    • Meyohas MC, Roux P, Bollens D et al. Pulmonary cryptococcosis: Localized and disseminated infections in 27 patients with AIDS. Clin. Infect. Dis. 21(3), 628-633 (1995).
    • (1995) Clin. Infect. Dis , vol.21 , Issue.3 , pp. 628-633
    • Meyohas, M.C.1    Roux, P.2    Bollens, D.3
  • 52
    • 0032810567 scopus 로고    scopus 로고
    • The capsule of Cryptococcus neoformans reduces T-lymphocyte proliferation by reducing phagocytosis, which can be restored with anticapsular antibody
    • Syme RM, Bruno TF, Kozel TR, Mody CH. The capsule of Cryptococcus neoformans reduces T-lymphocyte proliferation by reducing phagocytosis, which can be restored with anticapsular antibody. Infect. Immun. 67(9), 4620-4627 (1999).
    • (1999) Infect. Immun , vol.67 , Issue.9 , pp. 4620-4627
    • Syme, R.M.1    Bruno, T.F.2    Kozel, T.R.3    Mody, C.H.4
  • 53
    • 0028489517 scopus 로고
    • Role of human alveolar macrophages as antigen-presenting cells in Cryptococcus neoformans infection
    • Vecchiarelli A, Dottorini M, Pietrella D et al. Role of human alveolar macrophages as antigen-presenting cells in Cryptococcus neoformans infection. Am. J. Respir. Cell. Mol. Biol. 11(2), 130-137 (1994).
    • (1994) Am. J. Respir. Cell. Mol. Biol , vol.11 , Issue.2 , pp. 130-137
    • Vecchiarelli, A.1    Dottorini, M.2    Pietrella, D.3
  • 54
    • 84860739881 scopus 로고    scopus 로고
    • Difference in Cryptococcus neoformans cellular and capsule size in sequential pulmonary and meningeal infection: A postmortem study
    • Xie S, Sao R, Braun A, Bottone EJ. Difference in Cryptococcus neoformans cellular and capsule size in sequential pulmonary and meningeal infection: A postmortem study. Diagn. Microbiol. Infect. Dis. 73(1), 49-52 (2012).
    • (2012) Diagn. Microbiol. Infect. Dis , vol.73 , Issue.1 , pp. 49-52
    • Xie, S.1    Sao, R.2    Braun, A.3    Bottone, E.J.4
  • 55
    • 59849118749 scopus 로고    scopus 로고
    • App1: An antiphagocytic protein that binds to complement receptors 3 and 2
    • Stano P, Williams V, Villani M et al. App1: An antiphagocytic protein that binds to complement receptors 3 and 2. J. Immunol. 182(1), 84-91 (2009).
    • (2009) J. Immunol , vol.182 , Issue.1 , pp. 84-91
    • Stano, P.1    Williams, V.2    Villani, M.3
  • 56
    • 79952643476 scopus 로고    scopus 로고
    • A major role for capsule-independent phagocytosisinhibitory mechanisms in mammalian infection by Cryptococcus neoformans
    • Chun CD, Brown JC, Madhani HD. A major role for capsule-independent phagocytosisinhibitory mechanisms in mammalian infection by Cryptococcus neoformans. Cell Host Microbe 9(3), 243-251 (2011
    • (2011) Cell Host Microbe , vol.9 , Issue.3 , pp. 243-251
    • Chun, C.D.1    Brown, J.C.2    Madhani, H.D.3
  • 57
    • 84856956876 scopus 로고    scopus 로고
    • Catch me if you can: Phagocytosis and killing avoidance by Cryptococcus neoformans
    • Garcia-Rodas R, Zaragoza O. Catch me if you can: Phagocytosis and killing avoidance by Cryptococcus neoformans. FEMS Immunol. Med. Microbiol. 64(2), 147-161 (2012).
    • (2012) FEMS Immunol. Med. Microbiol , vol.64 , Issue.2 , pp. 147-161
    • Garcia-Rodas, R.1    Zaragoza, O.2
  • 58
    • 23344443130 scopus 로고    scopus 로고
    • Cryptococcus neoformans a strains preferentially disseminate to the central nervous system during coinfection
    • Nielsen K, Cox GM, Litvintseva AP et al. Cryptococcus neoformans a strains preferentially disseminate to the central nervous system during coinfection. Infect. Immun. 73(8), 4922-4933 (2005).
    • (2005) Infect. Immun , vol.73 , Issue.8 , pp. 4922-4933
    • Nielsen, K.1    Cox, G.M.2    Litvintseva, A.P.3
  • 60
    • 77954677679 scopus 로고    scopus 로고
    • Cryptococcal cell morphology affects host cell interactions and pathogenicity
    • Okagaki LH, Strain AK, Nielsen JN et al. Cryptococcal cell morphology affects host cell interactions and pathogenicity. Plos Pathog. 6(6), e1000953 (2010).
    • (2010) Plos Pathog , vol.6 , Issue.6
    • Okagaki, L.H.1    Strain, A.K.2    Nielsen, J.N.3
  • 61
    • 84861683800 scopus 로고    scopus 로고
    • Titan cells confer protection from phagocytosis in Cryptococcus neoformans infections
    • Okagaki LH, Nielsen K. Titan cells confer protection from phagocytosis in Cryptococcus neoformans infections. Eukaryot. Cell 11(6), 820-826 (2012).
    • (2012) Eukaryot. Cell , vol.11 , Issue.6 , pp. 820-826
    • Okagaki, L.H.1    Nielsen, K.2
  • 63
    • 0023112301 scopus 로고
    • Production, characterization, and antibody specificity of a mouse monoclonal antibody reactive with Cryptococcus neoformans capsular polysaccharide
    • Dromer F, Salamero J, Contrepois A, Carbon C, Yeni P. Production, characterization, and antibody specificity of a mouse monoclonal antibody reactive with Cryptococcus neoformans capsular polysaccharide. Infect. Immun. 55(3), 742-748 (1987).
    • (1987) Infect. Immun , vol.55 , Issue.3 , pp. 742-748
    • Dromer, F.1    Salamero, J.2    Contrepois, A.3    Carbon, C.4    Yeni, P.5
  • 64
    • 0023815541 scopus 로고
    • Strain variation in phagocytosis of Cryptococcus neoformans: Dissociation of susceptibility to phagocytosis from activation and binding of opsonic fragments of C3
    • Kozel TR, Pfrommer GS, Guerlain AS, Highison BA, Highison GJ. Strain variation in phagocytosis of Cryptococcus neoformans: Dissociation of susceptibility to phagocytosis from activation and binding of opsonic fragments of C3. Infect. Immun. 56(11), 2794-2800 (1988).
    • (1988) Infect. Immun , vol.56 , Issue.11 , pp. 2794-2800
    • Kozel, T.R.1    Pfrommer, G.S.2    Guerlain, A.S.3    Highison, B.A.4    Highison, G.J.5
  • 65
    • 0023395442 scopus 로고
    • Production and characterization of monoclonal antibodies specific for Cryptococcus neoformans capsular polysaccharide
    • Eckert TF, Kozel TR. Production and characterization of monoclonal antibodies specific for Cryptococcus neoformans capsular polysaccharide. Infect. Immun. 55(8), 1895-1899 (1987).
    • (1987) Infect. Immun , vol.55 , Issue.8 , pp. 1895-1899
    • Eckert, T.F.1    Kozel, T.R.2
  • 66
    • 0029046516 scopus 로고
    • Analysis of human monoclonal antibodies elicited by vaccination with a Cryptococcus neoformans glucuronoxylomannan capsular polysaccharide vaccine
    • Pirofski L, Lui R, DeShaw M, Kressel AB, Zhong Z. Analysis of human monoclonal antibodies elicited by vaccination with a Cryptococcus neoformans glucuronoxylomannan capsular polysaccharide vaccine. Infect. Immun. 63(8), 3005-3014 (1995).
    • (1995) Infect. Immun , vol.63 , Issue.8 , pp. 3005-3014
    • Pirofski, L.1    Lui, R.2    DeShaw, M.3    Kressel, A.B.4    Zhong, Z.5
  • 67
    • 0024387697 scopus 로고
    • Characterization of Cryptococcus neoformans capsular glucuronoxylomannan polysaccharide with monoclonal antibodies
    • Todaro-Luck F, Reiss E, Cherniak R, Kaufman L. Characterization of Cryptococcus neoformans capsular glucuronoxylomannan polysaccharide with monoclonal antibodies. Infect. Immun. 57(12), 3882-3887 (1989).
    • (1989) Infect. Immun , vol.57 , Issue.12 , pp. 3882-3887
    • Todaro-Luck, F.1    Reiss, E.2    Cherniak, R.3    Kaufman, L.4
  • 68
    • 0022620944 scopus 로고
    • Activation of the complement system by Cryptococcus neoformans leads to binding of iC3b to the yeast
    • Kozel TR, Pfrommer GS. Activation of the complement system by Cryptococcus neoformans leads to binding of iC3b to the yeast. Infect. Immun. 52(1), 1-5 (1986).
    • (1986) Infect. Immun , vol.52 , Issue.1 , pp. 1-5
    • Kozel, T.R.1    Pfrommer, G.S.2
  • 69
    • 0024355263 scopus 로고
    • Activation and binding of opsonic fragments of C3 on encapsulated Cryptococcus neoformans by using an alternative complement pathway reconstituted from six isolated proteins
    • Kozel TR, Wilson MA, Pfrommer GS, Schlageter AM. Activation and binding of opsonic fragments of C3 on encapsulated Cryptococcus neoformans by using an alternative complement pathway reconstituted from six isolated proteins. Infect. Immun. 57(7), 1922-1927 (1989).
    • (1989) Infect. Immun , vol.57 , Issue.7 , pp. 1922-1927
    • Kozel, T.R.1    Wilson, M.A.2    Pfrommer, G.S.3    Schlageter, A.M.4
  • 70
    • 33750604745 scopus 로고    scopus 로고
    • Expulsion of live pathogenic yeast by macrophages
    • Ma H, Croudace JE, Lammas DA, May RC. Expulsion of live pathogenic yeast by macrophages. Curr. Biol. 16(21), 2156-2160 (2006).
    • (2006) Curr. Biol , vol.16 , Issue.21 , pp. 2156-2160
    • Ma, H.1    Croudace, J.E.2    Lammas, D.A.3    May, R.C.4
  • 71
    • 69149090138 scopus 로고    scopus 로고
    • The fatal fungal outbreak on Vancouver Island is characterized by enhanced intracellular parasitism driven by mitochondrial regulation
    • Ma H, Hagen F, Stekel DJ et al. The fatal fungal outbreak on Vancouver Island is characterized by enhanced intracellular parasitism driven by mitochondrial regulation. Proc. Natl Acad. Sci. USA 106(31), 12980-12985 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , Issue.31 , pp. 12980-12985
    • Ma, H.1    Hagen, F.2    Stekel, D.J.3
  • 72
    • 33750606979 scopus 로고    scopus 로고
    • Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosis by macrophages
    • Alvarez M, Casadevall A. Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosis by macrophages. Curr. Biol. 16(21), 2161-2165 (2006).
    • (2006) Curr. Biol , vol.16 , Issue.21 , pp. 2161-2165
    • Alvarez, M.1    Casadevall, A.2
  • 73
    • 77958144360 scopus 로고    scopus 로고
    • The human fungal pathogen Cryptococcus neoformans escapes macrophages by a phagosome emptying mechanism that is inhibited by Arp2/3 complex-mediated actin polymerisation
    • Johnston SA, May RC. The human fungal pathogen Cryptococcus neoformans escapes macrophages by a phagosome emptying mechanism that is inhibited by Arp2/3 complex-mediated actin polymerisation. Plos Pathog. 6(8), e1001041 (2010).
    • (2010) Plos Pathog , vol.6 , Issue.8
    • Johnston, S.A.1    May, R.C.2
  • 75
    • 34548728783 scopus 로고    scopus 로고
    • Cell-to-cell spread and massive vacuole formation after Cryptococcus neoformans infection of murine macrophages
    • Alvarez M, Casadevall A. Cell-to-cell spread and massive vacuole formation after Cryptococcus neoformans infection of murine macrophages. BMC Immunol. 8, 16 (2007).
    • (2007) BMC Immunol , vol.8 , pp. 16
    • Alvarez, M.1    Casadevall, A.2
  • 76
    • 0028946434 scopus 로고
    • Cryptococcus neoformans fails to induce nitric oxide synthase in primed murine macrophage-like cells
    • Naslund PK, Miller WC, Granger DL. Cryptococcus neoformans fails to induce nitric oxide synthase in primed murine macrophage-like cells. Infect. Immun. 63(4), 1298-1304 (1995).
    • (1995) Infect. Immun , vol.63 , Issue.4 , pp. 1298-1304
    • Naslund, P.K.1    Miller, W.C.2    Granger, D.L.3
  • 77
    • 51549103890 scopus 로고    scopus 로고
    • Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival
    • Zaragoza O, Chrisman CJ, Castelli MV et al. Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival. Cell. Microbiol. 10(10), 2043-2057 (2008).
    • (2008) Cell. Microbiol , vol.10 , Issue.10 , pp. 2043-2057
    • Zaragoza, O.1    Chrisman, C.J.2    Castelli, M.V.3
  • 78
    • 0029593539 scopus 로고
    • Cryptococcus neoformans survive and replicate in human microglia
    • Lee SC, Kress Y, Zhao ML, Dickson DW, Casadevall A. Cryptococcus neoformans survive and replicate in human microglia. Lab. Invest. 73(6), 871-879 (1995).
    • (1995) Lab. Invest , vol.73 , Issue.6 , pp. 871-879
    • Lee, S.C.1    Kress, Y.2    Zhao, M.L.3    Dickson, D.W.4    Casadevall, A.5
  • 79
    • 0037022671 scopus 로고    scopus 로고
    • Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasm
    • Tucker SC, Casadevall A. Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasm. Proc. Natl Acad. Sci. USA 99(5), 3165-3170 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , Issue.5 , pp. 3165-3170
    • Tucker, S.C.1    Casadevall, A.2
  • 81
    • 0002223485 scopus 로고    scopus 로고
    • Laccase and melanin in the pathogenesis of Cryptococcus neoformans
    • Williamson PR. Laccase and melanin in the pathogenesis of Cryptococcus neoformans. Front. Biosci. 2, E99-E107 (1997).
    • (1997) Front. Biosci , vol.2
    • Williamson, P.R.1
  • 83
    • 0036840642 scopus 로고    scopus 로고
    • Melanization of Cryptococcus neoformans and Histoplasma capsulatum reduces their susceptibilities to amphotericin B and caspofungin
    • van Duin D, Casadevall A, Nosanchuk JD. Melanization of Cryptococcus neoformans and Histoplasma capsulatum reduces their susceptibilities to amphotericin B and caspofungin. Antimicrob. Agents Chemother. 46(11), 3394-3400 (2002).
    • (2002) Antimicrob. Agents Chemother , vol.46 , Issue.11 , pp. 3394-3400
    • Van Duin, D.1    Casadevall, A.2    Nosanchuk, J.D.3
  • 84
    • 66749118328 scopus 로고    scopus 로고
    • Activity of contemporary antifungal agents, including the novel echinocandin anidulafungin, tested against Candida spp., Cryptococcus spp., and Aspergillus spp: Report from the sentry antimicrobial surveillance program (2006 to 2007
    • Messer SA, Moet GJ, Kirby JT, Jones RN. Activity of contemporary antifungal agents, including the novel echinocandin anidulafungin, tested against Candida spp., Cryptococcus spp., and Aspergillus spp.: Report from the SENTRY Antimicrobial Surveillance Program (2006 to 2007). J. Clin. Microbiol. 47(6), 1942-1946 (2009).
    • (2009) J. Clin. Microbiol , vol.47 , Issue.6 , pp. 1942-1946
    • Messer, S.A.1    Moet, G.J.2    Kirby, J.T.3    Jones, R.N.4
  • 85
    • 80054915824 scopus 로고    scopus 로고
    • Variation in chromosome copy number influences the virulence of Cryptococcus neoformans and occurs in isolates from AIDS patients
    • Hu G, Wang J, Choi J et al. Variation in chromosome copy number influences the virulence of Cryptococcus neoformans and occurs in isolates from AIDS patients. BMC Genomics 12, 526 (2011).
    • (2011) BMC Genomics , vol.12 , Issue.526
    • Hu, G.1    Wang, J.2    Choi, J.3
  • 86
    • 34247547435 scopus 로고    scopus 로고
    • Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans
    • Chang YC, Bien CM, Lee H, Espenshade PJ, Kwon-Chung K. Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans. Mol. Microbiol. 64(3), 614-629 (2007).
    • (2007) Mol. Microbiol , vol.64 , Issue.3 , pp. 614-629
    • Chang, Y.C.1    Bien, C.M.2    Lee, H.3    Espenshade, P.J.4    Kwon-Chung, K.5
  • 87
    • 84855196338 scopus 로고    scopus 로고
    • Cryptococcus neoformans requires a functional glycolytic pathway for disease but not persistence in the host
    • Price MS, Betancourt-Quiroz M, Price JL et al. Cryptococcus neoformans requires a functional glycolytic pathway for disease but not persistence in the host. MBio 2(3), e00103-11 (2011).
    • (2011) MBio , vol.2 , Issue.3
    • Price, M.S.1    Betancourt-Quiroz, M.2    Price, J.L.3
  • 88
    • 23844483451 scopus 로고    scopus 로고
    • Cryptococcus neoformans gene expression during murine macrophage infection
    • Fan W, Kraus PR, Boily MJ, Heitman J. Cryptococcus neoformans gene expression during murine macrophage infection. Eukaryot. Cell 4(8), 1420-1433 (2005).
    • (2005) Eukaryot. Cell , vol.4 , Issue.8 , pp. 1420-1433
    • Fan, W.1    Kraus, P.R.2    Boily, M.J.3    Heitman, J.4
  • 89
    • 50049125079 scopus 로고    scopus 로고
    • Metabolic adaptation in Cryptococcus neoformans during early murine pulmonary infection
    • Hu G, Cheng PY, Sham A, Perfect JR, Kronstad JW. Metabolic adaptation in Cryptococcus neoformans during early murine pulmonary infection. Mol. Microbiol. 69(6), 1456-1475 (2008).
    • (2008) Mol. Microbiol , vol.69 , Issue.6 , pp. 1456-1475
    • Hu, G.1    Cheng, P.Y.2    Sham, A.3    Perfect, J.R.4    Kronstad, J.W.5
  • 90
    • 84865660055 scopus 로고    scopus 로고
    • Peroxisomal and mitochondrial boxidation influence the virulence of the pathogenic fungus Cryptococcus neoformans
    • Kretschmer M, Wang J, Kronstad JW. Peroxisomal and mitochondrial boxidation influence the virulence of the pathogenic fungus Cryptococcus neoformans. Eukaryot. Cell 11(8), 1042-1054 (2012).
    • (2012) Eukaryot. Cell , vol.11 , Issue.8 , pp. 1042-1054
    • Kretschmer, M.1    Wang, J.2    Kronstad, J.W.3
  • 91
    • 0028069606 scopus 로고
    • Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans: Identification as a laccase
    • Williamson PR. Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans: Identification as a laccase. J. Bacteriol. 176(3), 656-664 (1994).
    • (1994) J. Bacteriol , vol.176 , Issue.3 , pp. 656-664
    • Williamson, P.R.1
  • 92
    • 77958599469 scopus 로고    scopus 로고
    • Ctr2 links copper homeostasis to polysaccharide capsule formation and phagocytosis inhibition in the human fungal pathogen Cryptococcus neoformans
    • Chun CD, Madhani HD. Ctr2 links copper homeostasis to polysaccharide capsule formation and phagocytosis inhibition in the human fungal pathogen Cryptococcus neoformans. Plos One 5(9), e12503 (2010).
    • (2010) Plos One , vol.5 , Issue.9
    • Chun, C.D.1    Madhani, H.D.2
  • 93
    • 33847368172 scopus 로고    scopus 로고
    • Role of a CUF1/CTR4 copper regulatory axis in the virulence of Cryptococcus neoformans
    • Waterman SR, Hacham M, Hu G et al. Role of a CUF1/CTR4 copper regulatory axis in the virulence of Cryptococcus neoformans. J. Clin. Invest. 117(3), 794-802 (2007).
    • (2007) J. Clin. Invest , vol.117 , Issue.3 , pp. 794-802
    • Waterman, S.R.1    Hacham, M.2    Hu, G.3
  • 94
    • 80053538956 scopus 로고    scopus 로고
    • Effects of microplusin, a copper-chelating antimicrobial peptide, against Cryptococcus neoformans
    • Silva FD, Rossi DC, Martinez LR et al. Effects of microplusin, a copper-chelating antimicrobial peptide, against Cryptococcus neoformans. FEMS Microbiol. Lett. 324(1), 64-72 (2011).
    • (2011) FEMS Microbiol. Lett , vol.324 , Issue.1 , pp. 64-72
    • Silva, F.D.1    Rossi, D.C.2    Martinez, L.R.3
  • 96
    • 33746872950 scopus 로고    scopus 로고
    • Iron uptake in fungi: A system for every source
    • Philpott CC. Iron uptake in fungi: A system for every source. Biochim. Biophys. Acta 1763(7), 636-645 (2006).
    • (2006) Biochim. Biophys. Acta , vol.1763 , Issue.7 , pp. 636-645
    • Philpott, C.C.1
  • 97
    • 70349706237 scopus 로고    scopus 로고
    • Role of ferroxidases in iron uptake and virulence of Cryptococcus neoformans
    • Jung WH, Hu G, Kuo W, Kronstad JW. Role of ferroxidases in iron uptake and virulence of Cryptococcus neoformans. Eukaryot. Cell 8(10), 1511-1520 (2009).
    • (2009) Eukaryot. Cell , vol.8 , Issue.10 , pp. 1511-1520
    • Jung, W.H.1    Hu, G.2    Kuo, W.3    Kronstad, J.W.4
  • 98
    • 38049146021 scopus 로고    scopus 로고
    • Iron and fungal pathogenesis: A case study with Cryptococcus neoformans
    • Jung WH, Kronstad JW. Iron and fungal pathogenesis: A case study with Cryptococcus neoformans. Cell. Microbiol. 10(2), 277-284 (2008).
    • (2008) Cell. Microbiol , vol.10 , Issue.2 , pp. 277-284
    • Jung, W.H.1    Kronstad, J.W.2
  • 99
    • 79959848082 scopus 로고    scopus 로고
    • Functional analysis of host factors that mediate the intracellular lifestyle of Cryptococcus neoformans
    • Qin QM, Luo J, Lin X et al. Functional analysis of host factors that mediate the intracellular lifestyle of Cryptococcus neoformans. Plos Pathog. 7(6), e1002078 (2011).
    • (2011) Plos Pathog , vol.7 , Issue.6
    • Qin, Q.M.1    Luo, J.2    Lin, X.3
  • 100
    • 84867605302 scopus 로고    scopus 로고
    • Macrophage autophagy in immunity to Cryptococcus neoformans and Candida albicans
    • Nicola AM, Albuquerque P, Martinez LR et al. Macrophage autophagy in immunity to Cryptococcus neoformans and Candida albicans. Infect. Immun. 80(9), 3065-3076 (2012).
    • (2012) Infect. Immun , vol.80 , Issue.9 , pp. 3065-3076
    • Nicola, A.M.1    Albuquerque, P.2    Martinez, L.R.3
  • 101
    • 73549089697 scopus 로고    scopus 로고
    • Robust Th1 and Th17 immunity supports pulmonary clearance but cannot prevent systemic dissemination of highly virulent Cryptococcus neoformans H99
    • Zhang Y, Wang F, Tompkins KC et al. Robust Th1 and Th17 immunity supports pulmonary clearance but cannot prevent systemic dissemination of highly virulent Cryptococcus neoformans H99. Am. J. Pathol. 175(6), 2489-2500 (2009).
    • (2009) Am. J. Pathol , vol.175 , Issue.6 , pp. 2489-2500
    • Zhang, Y.1    Wang, F.2    Tompkins, K.C.3
  • 102
    • 62549097216 scopus 로고    scopus 로고
    • Cryptococcal urease promotes the accumulation of immature dendritic cells and a non-protective T2 immune response within the lung
    • Osterholzer JJ, Surana R, Milam JE et al. Cryptococcal urease promotes the accumulation of immature dendritic cells and a non-protective T2 immune response within the lung. Am. J. Pathol. 174(3), 932-943 (2009).
    • (2009) Am. J. Pathol , vol.174 , Issue.3 , pp. 932-943
    • Osterholzer, J.J.1    Surana, R.2    Milam, J.E.3
  • 103
    • 84860564696 scopus 로고    scopus 로고
    • Capsular material of Cryptococcus neoformans: Virulence and much more
    • doi:10.1007/s11046-011-9513-8 Epub ahead of print
    • Vecchiarelli A, Monari C. Capsular material of Cryptococcus neoformans: Virulence and much more. Mycopathologia doi:10.1007/s11046-011-9513-8 (2012) (Epub ahead of print).
    • (2012) Mycopathologia
    • Vecchiarelli, A.1    Monari, C.2
  • 104
    • 33748061664 scopus 로고    scopus 로고
    • Role of capsule and interleukin-6 in long-term immune control of Cryptococcus neoformans infection by specifically activated human peripheral blood mononuclear cells
    • Siddiqui AA, Shattock RJ, Harrison TS. Role of capsule and interleukin-6 in long-term immune control of Cryptococcus neoformans infection by specifically activated human peripheral blood mononuclear cells. Infect. Immun. 74(9), 5302-5310 (2006).
    • (2006) Infect. Immun , vol.74 , Issue.9 , pp. 5302-5310
    • Siddiqui, A.A.1    Shattock, R.J.2    Harrison, T.S.3
  • 105
    • 84859979283 scopus 로고    scopus 로고
    • Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells
    • Valdez PA, Vithayathil PJ, Janelsins BM, Shaffer AL, Williamson PR, Datta SK. Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells. Immunity 36(4), 668-679 (2012).
    • (2012) Immunity , vol.36 , Issue.4 , pp. 668-679
    • Valdez, P.A.1    Vithayathil, P.J.2    Janelsins, B.M.3    Shaffer, A.L.4    Williamson, P.R.5    Datta, S.K.6
  • 106
    • 0742269682 scopus 로고    scopus 로고
    • Cyclic AMP signaling in Cryptococcus neoformans
    • Pukkila-Worley R, Alspaugh JA. Cyclic AMP signaling in Cryptococcus neoformans. FEMS Yeast Res. 4(4-5), 361-367 (2004).
    • (2004) FEMS Yeast Res , vol.4 , Issue.4-5 , pp. 361-367
    • Pukkila-Worley, R.1    Alspaugh, J.A.2
  • 108
    • 10644253570 scopus 로고    scopus 로고
    • Cryptococcal phospholipases: A novel lysophospholipase discovered in the pathogenic fungus Cryptococcus gattii
    • Wright LC, Payne J, Santangelo RT et al. Cryptococcal phospholipases: A novel lysophospholipase discovered in the pathogenic fungus Cryptococcus gattii. Biochem. J. 384, 377-384 (2004).
    • (2004) Biochem. J. , vol.384 , pp. 377-384
    • Wright, L.C.1    Payne, J.2    Santangelo, R.T.3
  • 109
    • 0033958143 scopus 로고    scopus 로고
    • Potential role of phospholipases in virulence and fungal pathogenesis
    • table of contents
    • Ghannoum MA. Potential role of phospholipases in virulence and fungal pathogenesis. Clin. Microbiol. Rev. 13(1), 122-143, table of contents (2000).
    • (2000) Clin. Microbiol. Rev , vol.13 , Issue.1 , pp. 122-143
    • Ghannoum, M.A.1
  • 110
    • 1842431591 scopus 로고    scopus 로고
    • Role of extracellular phospholipases and mononuclear phagocytes in dissemination of cryptococcosis in a murine model
    • Santangelo R, Zoellner H, Sorrell T et al. Role of extracellular phospholipases and mononuclear phagocytes in dissemination of cryptococcosis in a murine model. Infect. Immun. 72(4), 2229-2239 (2004).
    • (2004) Infect. Immun , vol.72 , Issue.4 , pp. 2229-2239
    • Santangelo, R.1    Zoellner, H.2    Sorrell, T.3
  • 111
    • 0038054472 scopus 로고    scopus 로고
    • The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans
    • Steenbergen JN, Casadevall A. The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans. Microbes Infect. 5(7), 667-675 (2003).
    • (2003) Microbes Infect , vol.5 , Issue.7 , pp. 667-675
    • Steenbergen, J.N.1    Casadevall, A.2
  • 112
    • 33846419540 scopus 로고    scopus 로고
    • Cryptococcal lipid metabolism: Phospholipase B1 is implicated in transcellular metabolism of macrophagederived lipids
    • Wright LC, Santangelo RM, Ganendren R, Payne J, Djordjevic JT, Sorrell TC. Cryptococcal lipid metabolism: Phospholipase B1 is implicated in transcellular metabolism of macrophagederived lipids. Eukaryot. Cell 6(1), 37-47 (2007).
    • (2007) Eukaryot. Cell , vol.6 , Issue.1 , pp. 37-47
    • Wright, L.C.1    Santangelo, R.M.2    Ganendren, R.3    Payne, J.4    Djordjevic, J.T.5    Sorrell, T.C.6
  • 113
    • 0037373354 scopus 로고    scopus 로고
    • Role of PLB1 in pulmonary inflammation and cryptococcal eicosanoid production
    • Noverr MC, Cox GM, Perfect JR, Huffnagle GB. Role of PLB1 in pulmonary inflammation and cryptococcal eicosanoid production. Infect. Immun. 71(3), 1538-1547 (2003).
    • (2003) Infect. Immun , vol.71 , Issue.3 , pp. 1538-1547
    • Noverr, M.C.1    Cox, G.M.2    Perfect, J.R.3    Huffnagle, G.B.4
  • 114
    • 84867710310 scopus 로고    scopus 로고
    • Role of phospholipases in fungal fitness, pathogenicity, and drug development - lessons from Cryptococcus neoformans
    • Djordjevic JT. Role of phospholipases in fungal fitness, pathogenicity, and drug development - lessons from Cryptococcus neoformans. Front. Microbiol. 1, 125 (2010).
    • (2010) Front. Microbiol , vol.1 , Issue.125
    • Djordjevic, J.T.1
  • 115
    • 0031019618 scopus 로고    scopus 로고
    • Phospholipase activity in Cryptococcus neoformans: A new virulence factor
    • Chen SC, Muller M, Zhou JZ, Wright LC, Sorrell TC. Phospholipase activity in Cryptococcus neoformans: A new virulence factor? J. Infect. Dis. 175(2), 414-420 (1997).
    • (1997) J. Infect. Dis , vol.175 , Issue.2 , pp. 414-420
    • Chen, S.C.1    Muller, M.2    Zhou, J.Z.3    Wright, L.C.4    Sorrell, T.C.5
  • 116
    • 0035179848 scopus 로고    scopus 로고
    • Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans
    • Cox GM, McDade HC, Chen SC et al. Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformans. Mol. Microbiol. 39(1), 166-175 (2001).
    • (2001) Mol. Microbiol , vol.39 , Issue.1 , pp. 166-175
    • Cox, G.M.1    McDade, H.C.2    Chen, S.C.3
  • 117
    • 84866312565 scopus 로고    scopus 로고
    • Cryptococcus neoformans phospholipase B1 activates host cell Rac1 for traversal across the blood-brain barrier
    • Maruvada R, Zhu L, Pearce D et al. Cryptococcus neoformans phospholipase B1 activates host cell Rac1 for traversal across the blood-brain barrier. Cell. Microbiol. 14(10), 1544-1553 (2012
    • (2012) Cell. Microbiol , vol.14 , Issue.10 , pp. 1544-1553
    • Maruvada, R.1    Zhu, L.2    Pearce, D.3
  • 118
    • 0029793565 scopus 로고    scopus 로고
    • Extracellular proteinase activity of Cryptococcus neoformans
    • Chen LC, Blank ES, Casadevall A. Extracellular proteinase activity of Cryptococcus neoformans. Clin. Diagn. Lab. Immunol. 3(5), 570-574 (1996).
    • (1996) Clin. Diagn. Lab. Immunol , vol.3 , Issue.5 , pp. 570-574
    • Chen, L.C.1    Blank, E.S.2    Casadevall, A.3
  • 120
    • 1942533402 scopus 로고    scopus 로고
    • Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasion
    • Olszewski MA, Noverr MC, Chen GH et al. Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasion. Am. J. Pathol. 164(5), 1761-1771 (2004).
    • (2004) Am. J. Pathol , vol.164 , Issue.5 , pp. 1761-1771
    • Olszewski, M.A.1    Noverr, M.C.2    Chen, G.H.3
  • 121
    • 13244265941 scopus 로고    scopus 로고
    • Capsule structure changes associated with Cryptococcus neoformans crossing of the blood-brain barrier
    • Charlier C, Chretien F, Baudrimont M, Mordelet E, Lortholary O, Dromer F. Capsule structure changes associated with Cryptococcus neoformans crossing of the blood-brain barrier. Am. J. Pathol. 166(2), 421-432 (2005).
    • (2005) Am. J. Pathol , vol.166 , Issue.2 , pp. 421-432
    • Charlier, C.1    Chretien, F.2    Baudrimont, M.3    Mordelet, E.4    Lortholary, O.5    Dromer, F.6
  • 122
    • 77951842492 scopus 로고    scopus 로고
    • Real-time imaging of trapping and urease-dependent transmigration of Cryptococcus neoformans in mouse brain
    • Shi M, Li SS, Zheng C et al. Real-time imaging of trapping and urease-dependent transmigration of Cryptococcus neoformans in mouse brain. J. Clin. Invest. 120(5), 1683-1693 (2010
    • (2010) J. Clin. Invest , vol.120 , Issue.5 , pp. 1683-1693
    • Shi, M.1    Li, S.S.2    Zheng, C.3
  • 123
    • 70450263474 scopus 로고    scopus 로고
    • Cellular elements of the blood-brain barrier
    • Correale J, Villa A. Cellular elements of the blood-brain barrier. Neurochem. Res. 34(12), 2067-2077 (2009).
    • (2009) Neurochem. Res , vol.34 , Issue.12 , pp. 2067-2077
    • Correale, J.1    Villa, A.2
  • 124
    • 27744460321 scopus 로고    scopus 로고
    • Blood-brain barrier-specific properties of a human adult brain endothelial cell line
    • Weksler BB, Subileau EA, Perriere N et al. Blood-brain barrier-specific properties of a human adult brain endothelial cell line. FASEB J. 19(13), 1872-1874 (2005).
    • (2005) FASEB J. , vol.19 , Issue.13 , pp. 1872-1874
    • Weksler, B.B.1    Subileau, E.A.2    Perriere, N.3
  • 125
    • 33845966079 scopus 로고    scopus 로고
    • Tight junction protein expression and barrier properties of immortalized mouse brain microvessel endothelial cells
    • Brown RC, Morris AP, O'Neil RG. Tight junction protein expression and barrier properties of immortalized mouse brain microvessel endothelial cells. Brain Res. 1130(1), 17-30 (2007).
    • (2007) Brain Res , vol.1130 , Issue.1 , pp. 17-30
    • Brown, R.C.1    Morris, A.P.2    O'Neil, R.G.3
  • 126
    • 30344467870 scopus 로고    scopus 로고
    • Early capsule structure changes associated with Cryptococcus neoformans crossing of the blood-brain barrier
    • Paris
    • Charlier C, Chretien F, Lortholary O, Dromer F. [Early capsule structure changes associated with Cryptococcus neoformans crossing of the blood-brain barrier.] Med. Sci. (Paris) 21(8-9), 685-687 (2005).
    • (2005) Med. Sci , vol.21 , Issue.8-9 , pp. 685-687
    • Charlier, C.1    Chretien, F.2    Lortholary, O.3    Dromer, F.4
  • 127
    • 47549115574 scopus 로고    scopus 로고
    • Mechanisms of microbial traversal of the blood-brain barrier
    • Kim KS. Mechanisms of microbial traversal of the blood-brain barrier. Nat. Rev. Microbiol. 6(8), 625-634 (2008).
    • (2008) Nat. Rev. Microbiol , vol.6 , Issue.8 , pp. 625-634
    • Kim, K.S.1
  • 128
    • 58449131342 scopus 로고    scopus 로고
    • Evidence of a role for monocytes in dissemination and brain invasion by Cryptococcus neoformans
    • Charlier C, Nielsen K, Daou S, Brigitte M, Chretien F, Dromer F. Evidence of a role for monocytes in dissemination and brain invasion by Cryptococcus neoformans. Infect. Immun. 77(1), 120-127 (2009
    • (2009) Infect. Immun , vol.77 , Issue.1 , pp. 120-127
    • Charlier, C.1    Nielsen, K.2    Daou, S.3    Brigitte, M.4    Chretien, F.5    Dromer, F.6
  • 129
    • 0034864222 scopus 로고    scopus 로고
    • Dynamic changes in the morphology of Cryptococcus neoformans during murine pulmonary infection
    • Feldmesser M, Kress Y, Casadevall A. Dynamic changes in the morphology of Cryptococcus neoformans during murine pulmonary infection. Microbiology 147, 2355-2365 (2001).
    • (2001) Microbiology , vol.147 , pp. 2355-2365
    • Feldmesser, M.1    Kress, Y.2    Casadevall, A.3
  • 130
    • 0033709060 scopus 로고    scopus 로고
    • Leukocyte-facilitated entry of intracellular pathogens into the central nervous system
    • Drevets DA, Leenen PJ. Leukocyte-facilitated entry of intracellular pathogens into the central nervous system. Microbes Infect. 2(13), 1609-1618 (2000).
    • (2000) Microbes Infect , vol.2 , Issue.13 , pp. 1609-1618
    • Drevets, D.A.1    Leenen, P.J.2
  • 131
    • 2142772699 scopus 로고    scopus 로고
    • Invasion of the central nervous system by intracellular bacteria
    • Drevets DA, Leenen PJ, Greenfield RA. Invasion of the central nervous system by intracellular bacteria. Clin. Microbiol. Rev. 17(2), 323-347 (2004).
    • (2004) Clin. Microbiol. Rev , vol.17 , Issue.2 , pp. 323-347
    • Drevets, D.A.1    Leenen, P.J.2    Greenfield, R.A.3
  • 132
    • 0033008857 scopus 로고    scopus 로고
    • Dissemination of Listeria monocytogenes by infected phagocytes
    • Drevets DA. Dissemination of Listeria monocytogenes by infected phagocytes. Infect. Immun. 67(7), 3512-3517 (1999).
    • (1999) Infect. Immun , vol.67 , Issue.7 , pp. 3512-3517
    • Drevets, D.A.1
  • 133
    • 33845764425 scopus 로고    scopus 로고
    • HIV-1 gp120 compromises blood-brain barrier integrity and enhances monocyte migration across blood-brain barrier: Implication for viral neuropathogenesis
    • Kanmogne GD, Schall K, Leibhart J, Knipe B, Gendelman HE, Persidsky Y. HIV-1 gp120 compromises blood-brain barrier integrity and enhances monocyte migration across blood-brain barrier: Implication for viral neuropathogenesis. J. Cereb. Blood Flow Metab. 27(1), 123-134 (2007).
    • (2007) J. Cereb. Blood Flow Metab , vol.27 , Issue.1 , pp. 123-134
    • Kanmogne, G.D.1    Schall, K.2    Leibhart, J.3    Knipe, B.4    Gendelman, H.E.5    Persidsky, Y.6
  • 134
    • 79952245370 scopus 로고    scopus 로고
    • Intracellular transport of Toxoplasma gondii through the blood-brain barrier
    • Lachenmaier SM, Deli MA, Meissner M, Liesenfeld O. Intracellular transport of Toxoplasma gondii through the blood-brain barrier. J. Neuroimmunol. 232(1-2), 119-130 (2011).
    • (2011) J. Neuroimmunol , vol.232 , Issue.1-2 , pp. 119-130
    • Lachenmaier, S.M.1    Deli, M.A.2    Meissner, M.3    Liesenfeld, O.4
  • 135
    • 2942541583 scopus 로고    scopus 로고
    • Toxoplasmosis
    • Montoya JG, Liesenfeld O. Toxoplasmosis. Lancet 363(9425), 1965-1976 (2004).
    • (2004) Lancet , vol.363 , Issue.9425 , pp. 1965-1976
    • Montoya, J.G.1    Liesenfeld, O.2
  • 136
    • 79959855148 scopus 로고    scopus 로고
    • Glycosaminoglycan binding facilitates entry of a bacterial pathogen into central nervous systems
    • Chang YC, Wang Z, Flax LA et al. Glycosaminoglycan binding facilitates entry of a bacterial pathogen into central nervous systems. Plos Pathog. 7(6), e1002082 (2011).
    • (2011) Plos Pathog , vol.7 , Issue.6
    • Chang, Y.C.1    Wang, Z.2    Flax, L.A.3
  • 137
    • 27744548828 scopus 로고    scopus 로고
    • Molecular epidemiology of clinical Cryptococcus neoformans strains from India
    • Jain N, Wickes BL, Keller SM et al. Molecular epidemiology of clinical Cryptococcus neoformans strains from India. J. Clin. Microbiol. 43(11), 5733-5742 (2005).
    • (2005) J. Clin. Microbiol , vol.43 , Issue.11 , pp. 5733-5742
    • Jain, N.1    Wickes, B.L.2    Keller, S.M.3
  • 138
    • 72449202243 scopus 로고    scopus 로고
    • Immortalized human brain endothelial cell line HCMEC/D3 as a model of the blood-brain barrier facilitates in vitro studies of central nervous system infection by Cryptococcus neoformans
    • Vu K, Weksler B, Romero I, Couraud PO, Gelli A. Immortalized human brain endothelial cell line HCMEC/D3 as a model of the blood-brain barrier facilitates in vitro studies of central nervous system infection by Cryptococcus neoformans. Eukaryot. Cell 8(11), 1803-1807 (2009).
    • (2009) Eukaryot. Cell , vol.8 , Issue.11 , pp. 1803-1807
    • Vu, K.1    Weksler, B.2    Romero, I.3    Couraud, P.O.4    Gelli, A.5
  • 139
    • 0242450370 scopus 로고    scopus 로고
    • Cryptococcus neoformans induces alterations in the cytoskeleton of human brain microvascular endothelial cells
    • Chen SH, Stins MF, Huang SH et al. Cryptococcus neoformans induces alterations in the cytoskeleton of human brain microvascular endothelial cells. J. Med. Microbiol. 52, 961-970 (2003).
    • (2003) J. Med. Microbiol , vol.52 , pp. 961-970
    • Chen, S.H.1    Stins, M.F.2    Huang, S.H.3
  • 140
    • 4444254158 scopus 로고    scopus 로고
    • Regulatory roles for the homeodomain and C2H2 zinc finger regions of Cryptococcus neoformans Ste12alphap
    • Chang YC, Wright LC, Tscharke RL, Sorrell TC, Wilson CF, Kwon-Chung K. Regulatory roles for the homeodomain and C2H2 zinc finger regions of Cryptococcus neoformans Ste12alphap. Mol. Microbiol. 53(5), 1385-1396 (2004).
    • (2004) Mol. Microbiol , vol.53 , Issue.5 , pp. 1385-1396
    • Chang, Y.C.1    Wright, L.C.2    Tscharke, R.L.3    Sorrell, T.C.4    Wilson, C.F.5    Kwon-Chung, K.6
  • 141
    • 4544298974 scopus 로고    scopus 로고
    • Cryptococcal yeast cells invade the central nervous system via transcellular penetration of the blood-brain barrier
    • Chang YC, Stins MF, McCaffery MJ et al. Cryptococcal yeast cells invade the central nervous system via transcellular penetration of the blood-brain barrier. Infect. Immun. 72(9), 4985-4995 (2004
    • (2004) Infect. Immun , vol.72 , Issue.9 , pp. 4985-4995
    • Chang, Y.C.1    Stins, M.F.2    McCaffery, M.J.3
  • 142
    • 43449130400 scopus 로고    scopus 로고
    • Involvement of human CD44 during Cryptococcus neoformans infection of brain microvascular endothelial cells
    • Jong A, Wu CH, Shackleford GM et al. Involvement of human CD44 during Cryptococcus neoformans infection of brain microvascular endothelial cells. Cell. Microbiol. 10(6), 1313-1326 (2008).
    • (2008) Cell. Microbiol , vol.10 , Issue.6 , pp. 1313-1326
    • Jong, A.1    Wu, C.H.2    Shackleford, G.M.3
  • 143
    • 80053417552 scopus 로고    scopus 로고
    • Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells is mediated through the lipid rafts-endocytic pathway via the dual specificity tyrosine phosphorylation-regulated kinase 3 (DYRK3
    • Huang SH, Long M, Wu CH et al. Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells is mediated through the lipid rafts-endocytic pathway via the dual specificity tyrosine phosphorylation- regulated kinase 3 (DYRK3). J. Biol. Chem. 286(40), 34761-34769 (2011).
    • (2011) J. Biol. Chem , vol.286 , Issue.40 , pp. 34761-34769
    • Huang, S.H.1    Long, M.2    Wu, C.H.3
  • 144
    • 0032768970 scopus 로고    scopus 로고
    • CD44 cell adhesion molecules
    • Goodison S, Urquidi V, Tarin D. CD44 cell adhesion molecules. Mol. Pathol. 52(4), 189-196 (1999).
    • (1999) Mol. Pathol , vol.52 , Issue.4 , pp. 189-196
    • Goodison, S.1    Urquidi, V.2    Tarin, D.3
  • 145
    • 0037227965 scopus 로고    scopus 로고
    • CD44: From adhesion molecules to signalling regulators
    • Ponta H, Sherman L, Herrlich PA. CD44: From adhesion molecules to signalling regulators. Nat. Rev. Mol. Cell. Biol. 4(1), 33-45 (2003).
    • (2003) Nat. Rev. Mol. Cell. Biol , vol.4 , Issue.1 , pp. 33-45
    • Ponta, H.1    Sherman, L.2    Herrlich, P.A.3
  • 147
    • 0035210645 scopus 로고    scopus 로고
    • Phenotypic switching of Cryptococcus neoformans occurs in vivo and influences the outcome of infection
    • Fries BC, Taborda CP, Serfass E, Casadevall A. Phenotypic switching of Cryptococcus neoformans occurs in vivo and influences the outcome of infection. J. Clin. Invest. 108(11), 1639-1648 (2001).
    • (2001) J. Clin. Invest , vol.108 , Issue.11 , pp. 1639-1648
    • Fries, B.C.1    Taborda, C.P.2    Serfass, E.3    Casadevall, A.4
  • 149
    • 33646556394 scopus 로고    scopus 로고
    • Phenotypic switching and its implications for the pathogenesis of Cryptococcus neoformans
    • Jain N, Guerrero A, Fries BC. Phenotypic switching and its implications for the pathogenesis of Cryptococcus neoformans. FEMS Yeast Res. 6(4), 480-488 (2006).
    • (2006) FEMS Yeast Res , vol.6 , Issue.4 , pp. 480-488
    • Jain, N.1    Guerrero, A.2    Fries, B.C.3
  • 150
    • 84859815859 scopus 로고    scopus 로고
    • Capsule independent uptake of the fungal pathogen Cryptococcus neoformans into brain microvascular endothelial cells
    • Sabiiti W, May RC. Capsule independent uptake of the fungal pathogen Cryptococcus neoformans into brain microvascular endothelial cells. Plos One 7(4), e35455 (2012).
    • (2012) Plos One , vol.7 , Issue.4
    • Sabiiti, W.1    May, R.C.2
  • 151
    • 66749148271 scopus 로고    scopus 로고
    • Surface-associated plasminogen binding of Cryptococcus neoformans promotes extracellular matrix invasion
    • Stie J, Bruni G, Fox D. Surface-associated plasminogen binding of Cryptococcus neoformans promotes extracellular matrix invasion. Plos One 4(6), e5780 (2009).
    • (2009) Plos One , vol.4 , Issue.6
    • Stie, J.1    Bruni, G.2    Fox, D.3
  • 152
    • 0033866453 scopus 로고    scopus 로고
    • Monocyte infiltration is highly associated with loss of the tight junction protein zonula occludens in HIV-1-associated dementia
    • Boven LA, Middel J, Verhoef J, De Groot CJ, Nottet HS. Monocyte infiltration is highly associated with loss of the tight junction protein zonula occludens in HIV-1-associated dementia. Neuropathol. Appl. Neurobiol. 26(4), 356-360 (2000).
    • (2000) Neuropathol. Appl. Neurobiol , vol.26 , Issue.4 , pp. 356-360
    • Boven, L.A.1    Middel, J.2    Verhoef, J.3    De Groot, C.J.4    Nottet, H.S.5
  • 153
    • 1842411268 scopus 로고    scopus 로고
    • Cellular aspects of HIV-1 infection of macrophages leading to neuronal dysfunction in in vitro models for HIV-1 encephalitis
    • Nottet HS, Bar DR, van Hassel H, Verhoef J, Boven LA. Cellular aspects of HIV-1 infection of macrophages leading to neuronal dysfunction in in vitro models for HIV-1 encephalitis. J. Leukoc. Biol. 62(1), 107-116 (1997).
    • (1997) J. Leukoc. Biol , vol.62 , Issue.1 , pp. 107-116
    • Nottet, H.S.1    Bar, D.R.2    Van Hassel, H.3    Verhoef, J.4    Boven, L.A.5
  • 154
    • 0037371137 scopus 로고    scopus 로고
    • HIV-1 Tat-mediated apoptosis in human brain microvascular endothelial cells
    • Kim TA, Avraham HK, Koh YH, Jiang S, Park IW, Avraham S. HIV-1 Tat-mediated apoptosis in human brain microvascular endothelial cells. J. Immunol. 170(5), 2629-2637 (2003).
    • (2003) J. Immunol , vol.170 , Issue.5 , pp. 2629-2637
    • Kim, T.A.1    Avraham, H.K.2    Koh, Y.H.3    Jiang, S.4    Park, I.W.5    Avraham, S.6
  • 155
    • 8444227370 scopus 로고    scopus 로고
    • HIV-1 Tat-mediated effects on focal adhesion assembly and permeability in brain microvascular endothelial cells
    • Avraham HK, Jiang S, Lee TH, Prakash O, Avraham S. HIV-1 Tat-mediated effects on focal adhesion assembly and permeability in brain microvascular endothelial cells. J. Immunol. 173(10), 6228-6233 (2004).
    • (2004) J. Immunol , vol.173 , Issue.10 , pp. 6228-6233
    • Avraham, H.K.1    Jiang, S.2    Lee, T.H.3    Prakash, O.4    Avraham, S.5
  • 157
    • 77955951360 scopus 로고    scopus 로고
    • Paucity of initial cerebrospinal fluid inflammation in cryptococcal meningitis is associated with subsequent immune reconstitution inflammatory syndrome
    • Boulware DR, Bonham SC, Meya DB et al. Paucity of initial cerebrospinal fluid inflammation in cryptococcal meningitis is associated with subsequent immune reconstitution inflammatory syndrome. J. Infect. Dis. 202(6), 962-970 (2010).
    • (2010) J. Infect. Dis , vol.202 , Issue.6 , pp. 962-970
    • Boulware, D.R.1    Bonham, S.C.2    Meya, D.B.3
  • 159
    • 0035196105 scopus 로고    scopus 로고
    • Clinical presentation, natural history, and cumulative death rates of 230 adults with primary cryptococcal meningitis in Zambian AIDS patients treated under local conditions
    • Mwaba P, Mwansa J, Chintu C et al. Clinical presentation, natural history, and cumulative death rates of 230 adults with primary cryptococcal meningitis in Zambian AIDS patients treated under local conditions. Postgrad. Med. J. 77(914), 769-773 (2001).
    • (2001) Postgrad. Med. J. , vol.77 , Issue.914 , pp. 769-773
    • Mwaba, P.1    Mwansa, J.2    Chintu, C.3
  • 160
    • 75749105005 scopus 로고    scopus 로고
    • Combination flucytosine and high-dose fluconazole compared with fluconazole monotherapy for the treatment of cryptococcal meningitis: A randomized trial in Malawi
    • Nussbaum JC, Jackson A, Namarika D et al. Combination flucytosine and high-dose fluconazole compared with fluconazole monotherapy for the treatment of cryptococcal meningitis: A randomized trial in Malawi. Clin. Infect. Dis. 50(3), 338-344 (2010).
    • (2010) Clin. Infect. Dis , vol.50 , Issue.3 , pp. 338-344
    • Nussbaum, J.C.1    Jackson, A.2    Namarika, D.3
  • 161
    • 0029818328 scopus 로고    scopus 로고
    • Pathology of cryptococcal meningoencephalitis: Analysis of 27 patients with pathogenetic implications
    • Lee SC, Dickson DW, Casadevall A. Pathology of cryptococcal meningoencephalitis: Analysis of 27 patients with pathogenetic implications. Hum. Pathol. 27(8), 839-847 (1996).
    • (1996) Hum. Pathol , vol.27 , Issue.8 , pp. 839-847
    • Lee, S.C.1    Dickson, D.W.2    Casadevall, A.3
  • 162
    • 75649136209 scopus 로고    scopus 로고
    • Histopathology of the arachnoid granulations and brain in HIV-associated cryptococcal meningitis:Correlation with cerebrospinal fluid pressure
    • Loyse A, Wainwright H, Jarvis JN et al. Histopathology of the arachnoid granulations and brain in HIV-associated cryptococcal meningitis:Correlation with cerebrospinal fluid pressure. AIDS 24(3), 405-410 (2010).
    • (2010) AIDS , vol.24 , Issue.3 , pp. 405-410
    • Loyse, A.1    Wainwright, H.2    Jarvis, J.N.3
  • 163
    • 64549108540 scopus 로고    scopus 로고
    • Relationship of cerebrospinal fluid pressure, fungal burden and outcome in patients with cryptococcal meningitis undergoing serial lumbar punctures
    • Bicanic T, Brouwer AE, Meintjes G et al. Relationship of cerebrospinal fluid pressure, fungal burden and outcome in patients with cryptococcal meningitis undergoing serial lumbar punctures. AIDS 23(6), 701-706 (2009).
    • (2009) AIDS , vol.23 , Issue.6 , pp. 701-706
    • Bicanic, T.1    Brouwer, A.E.2    Meintjes, G.3
  • 165
    • 77956855730 scopus 로고    scopus 로고
    • In-hospital mortality of HIV-infected cryptococcal meningitis patients with C. gattii and C. neoformans infection in Gaborone
    • Steele KT, Thakur R, Nthobatsang R, Steenhoff AP, Bisson GP. In-hospital mortality of HIV-infected cryptococcal meningitis patients with C. gattii and C. neoformans infection in Gaborone, Botswana. Med. Mycol. 48(8), 1112-1115 (2010).
    • (2010) Botswana. Med. Mycol , vol.48 , Issue.8 , pp. 1112-1115
    • Steele, K.T.1    Thakur, R.2    Nthobatsang, R.3    Steenhoff, A.P.4    Bisson, G.P.5
  • 166
    • 75749092958 scopus 로고    scopus 로고
    • Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of America
    • Perfect JR, Dismukes WE, Dromer F et al. Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the Infectious Diseases Society of America. Clin. Infect. Dis. 50(3), 291-322 (2010).
    • (2010) Clin. Infect. Dis , vol.50 , Issue.3 , pp. 291-322
    • Perfect, J.R.1    Dismukes, W.E.2    Dromer, F.3
  • 168
    • 84860595405 scopus 로고    scopus 로고
    • Ten challenges on Cryptococcus and cryptococcosis
    • Del Poeta M, Casadevall A. Ten challenges on Cryptococcus and cryptococcosis. Mycopathologia 173(5-6), 303-310 (2012).
    • (2012) Mycopathologia , vol.173 , Issue.5-6 , pp. 303-310
    • Del Poeta, M.1    Casadevall, A.2
  • 170
    • 84855898202 scopus 로고    scopus 로고
    • Environmental prevalence of Cryptococcus neoformans and Cryptococcus gattii in India: An update
    • Chowdhary A, Rhandhawa HS, Prakash A, Meis JF. Environmental prevalence of Cryptococcus neoformans and Cryptococcus gattii in India: An update. Crit. Rev. Microbiol. 38(1), 1-16 (2012).
    • (2012) Crit. Rev. Microbiol , vol.38 , Issue.1 , pp. 1-16
    • Chowdhary, A.1    Rhandhawa, H.S.2    Prakash, A.3    Meis, J.F.4
  • 171
    • 84859022940 scopus 로고    scopus 로고
    • Antifungal activity of the essential oils of Callitris neocaledonica and C sulcata heartwood (Cupressaceae
    • Waikedre J, Vitturo CI, Molina A et al. Antifungal activity of the essential oils of Callitris neocaledonica and C. sulcata heartwood (Cupressaceae). Chem. Biodivers. 9(3), 644-653 (2012).
    • (2012) Chem. Biodivers , vol.9 , Issue.3 , pp. 644-653
    • Waikedre, J.1    Vitturo, C.I.2    Molina, A.3
  • 172
    • 0018927330 scopus 로고
    • Chronic cryptococcal meningitis: A new experimental model in rabbits
    • Perfect JR, Lang SD, Durack DT. Chronic cryptococcal meningitis: A new experimental model in rabbits. Am. J. Pathol. 101(1), 177-194 (1980).
    • (1980) Am. J. Pathol , vol.101 , Issue.1 , pp. 177-194
    • Perfect, J.R.1    Lang, S.D.2    Durack, D.T.3
  • 173
    • 0036786526 scopus 로고    scopus 로고
    • Relationship of the glyoxylate pathway to the pathogenesis of Cryptococcus neoformans
    • Rude TH, Toffaletti DL, Cox GM, Perfect Jr. Relationship of the glyoxylate pathway to the pathogenesis of Cryptococcus neoformans. Infect. Immun. 70(10), 5684-5694 (2002).
    • (2002) Infect. Immun , vol.70 , Issue.10 , pp. 5684-5694
    • Rude, T.H.1    Toffaletti, D.L.2    Cox, G.M.3    Perfect, J.R.4
  • 174
    • 77957730037 scopus 로고    scopus 로고
    • Survival defects of Cryptococcus neoformans mutants exposed to human cerebrospinal fluid result in attenuated virulence in an experimental model of meningitis
    • Lee A, Toffaletti DL, Tenor J et al. Survival defects of Cryptococcus neoformans mutants exposed to human cerebrospinal fluid result in attenuated virulence in an experimental model of meningitis. Infect. Immun. 78(10), 4213-4225 (2010).
    • (2010) Infect. Immun , vol.78 , Issue.10 , pp. 4213-4225
    • Lee, A.1    Toffaletti, D.L.2    Tenor, J.3
  • 175
    • 80053645911 scopus 로고    scopus 로고
    • Comparisons of clinical features and mortality of cryptococcal meningitis between patients with and without human immunodeficiency virus infection
    • Lee YC, Wang JT, Sun HY, Chen YC. Comparisons of clinical features and mortality of cryptococcal meningitis between patients with and without human immunodeficiency virus infection. J. Microbiol. Immunol. Infect. 44(5), 338-345 (2011).
    • (2011) J. Microbiol. Immunol. Infect , vol.44 , Issue.5 , pp. 338-345
    • Lee, Y.C.1    Wang, J.T.2    Sun, H.Y.3    Chen, Y.C.4
  • 176
    • 40349096476 scopus 로고    scopus 로고
    • Iron source preference and regulation of iron uptake in Cryptococcus neoformans
    • Jung WH, Sham A, Lian T, Singh A, Kosman DJ, Kronstad JW. Iron source preference and regulation of iron uptake in Cryptococcus neoformans. Plos Pathog. 4(2), e45 (2008).
    • (2008) Plos Pathog , vol.4 , Issue.2
    • Jung, W.H.1    Sham, A.2    Lian, T.3    Singh, A.4    Kosman, D.J.5    Kronstad, J.W.6
  • 177
    • 0034967569 scopus 로고    scopus 로고
    • Traversal of Candida albicans across human blood-brain barrier in vitro
    • Jong AY, Stins MF, Huang SH, Chen SH, Kim KS. Traversal of Candida albicans across human blood-brain barrier in vitro. Infect. Immun. 69(7), 4536-4544 (2001).
    • (2001) Infect. Immun , vol.69 , Issue.7 , pp. 4536-4544
    • Jong, A.Y.1    Stins, M.F.2    Huang, S.H.3    Chen, S.H.4    Kim, K.S.5


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