Difference in Cryptococcus neoformans cellular and capsule size in sequential pulmonary and meningeal infection: A postmortem study

Diagnostic Microbiology and Infectious Disease

Volumn 73, Issue 1, 2012, Pages 49-52

  Xie, Steve ^a   Sao, Rahul ^b   Braun, Alex ^a   Bottone, Edward J ^a,b  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Capsule size; Cellular size; Cryptococcus neoformans; Meningeal infection; Pulmonary infection

Indexed keywords

ADULT; ARTICLE; BRAIN TISSUE; CADAVER; CAPSULE SIZE; CELL SIZE; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; DISEASE MODEL; EXPERIMENTAL MODEL; FATALITY; FUNGAL CELL; FUNGAL MENINGITIS; HEART TRANSPLANTATION; HISTOLOGY; HUMAN; HUMAN TISSUE; LUNG MYCOSIS; LUNG PARENCHYMA; MALE; PRIORITY JOURNAL; TISSUE SECTION;

AUTOPSY; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; FATAL OUTCOME; HISTOCYTOCHEMISTRY; HUMANS; MALE; MENINGITIS; MICROSCOPY; MIDDLE AGED; PNEUMONIA; POLYSACCHARIDES; VIRULENCE FACTORS;

EID: 84860739881     PISSN: 07328893     EISSN: 18790070     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2012.01.008     Document Type: Article

References (19)

1. Casadevall A, Perfect JR Cryptococcus neoformans 1998, American Society For Microbiology, Washington, DC.
2. Charlier C, Chrètien F, Baudrimont M, Mordele E, Lortholary O, Dromer F Capsule structure changes associated with Cryptococcus neoformans crossing of the blood-brain barrier. Am. J. Pathol. 2005, 166:421-432.
3. Charlier C, Nielsen K, Daou S, Brigitte M, Chrètien F, Dromer F Evidence for the role of monocytes in dissemination and brain invasion by Cryptococcus neoformans. Infec. Immun. 2009, 77:120-127.
4. Chrisman CJ, Albuquerque P, Guimaraes AJ, Nieves E, Casadevall A Phospholipids trigger Cryptococcus neoformans capsular enlargement during interaction with amoebae and macrophages. Plos. Pathog. 2011, 7:e002047.
5. Currie BP, Casadevall A Estimation of the prevalence of cryptococcal infection among patients infected with the human immunodeficiency virus in New York City. Clin. Infect. Dis. 1994, 19:1029-1033.
6. Feldmesser M, Kress Y, Casadevall A Dynamic changes in the morphology of Cryptococcus neoformans during murine pulmonary infection. Microbiol 2001, 147:2355-2365.
7. Fries BC, Taborda CP, Serfass E, Casadevall A Phenotypic switching of Cryptococcus neoformans occurs in vivo and influences the outcome of infection. J. Clin. Investig. 2001, 108:1639-1648.
8. Giles SS Elucidating the pathogenesis of spores from the human fungal pathogen Cryptococcus neoformans. Infect. Immun. 2009, 77:3491-3500.
9. Granger DL, Perfect JR, Durack DT Virulence of Cryptococcus neoformans. Regulation of capsule synthesis by carbon dioxide. J. Clin. Invest. 1985, 76:508-516.
10. Jain N, Hasan F, Fries BC Phenotypic switching in fungi. Curr. Fungal. Infec. Rep. 2008, 2:180-188.
11. Littman M, Tsubura E Effect of degree of encapsulation upon virulence of Cryptococcus neoformans. Proc. Soc. Exp. Boil. Med. 1959, 101:773-777.
12. Mcfadden D, Okagaki LH, Strain AK, Nielsen JN, Charlier C, Baltes NJ, et al. Cryptococcal cell morphology affects host cell interactions and pathogenicity. Plos. Pathog. 2010, 6:e1000953.
13. Park BJ, Wannemuehler KA, Marston B, Govender N, Pappas PG, Chiller TM Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS. AIDS 2009, 23:525-530.
14. Rivera J, Feldmesser M, Cammer M, Casadevall A Organ dependent thickness in Cryptococcus neoformans during experimental murine infection. Infect. Immun. 1988, 66:5027-5030.
15. Vartivarian SE, Anaissie EJ, Cowart RE, Sprigg HA, Tingler MJ, Jacobson ES Regulation of cryptococcal capsular polysaccharide by iron. J. Infect. Dis. 1993, 167:186-190.
16. Velagapudi R, Hsueh YP, Geunes-Boyer S, Wright JR, Heitman J Spores as infectious propagules of Cryptococcus. neoformans. Infect. Immun. 2009, 77:4345-4355.
17. Zaragoza O, Casadevall A Experimental modification of capsule size in Cryptococcus neoformans. Biol. Proc. 2004, 6:10-15.
18. Zaragoza O, Fries BC, Casadevall A Induction of capsule growth in Cryptococcus neoformans by mammalian serum and CO (2). Infect. Immun. 2003, 71:6155-6164.
19. Zaragoza O, Garcia-Rodas R, Nosanchuk JD, Cuenca-Estrella M, Rodriguez-Tudela JL, Casadevall A Fungal cell gigantism during mammalian infection. Plos. Pathog. 2010, 6:e1000945.