Survival defects of Cryptococcus neoformans mutants exposed to human cerebrospinal fluid result in attenuated virulence in an experimental model of meningitis

Infection and Immunity

Volumn 78, Issue 10, 2010, Pages 4213-4225

  Lee, Anthony ^a   Toffaletti, Dena L ^a   Tenor, Jennifer ^a   Soderblom, Erik J ^a   Thompson, J Will ^a   Moseley, M Arthur ^a   Price, Michael ^a   Perfect, John R ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; NEDD8 PROTEIN; PHOSPHATIDYLINOSITOL KINASE; VANCOMYCIN;

ANIMAL MODEL; ARTICLE; CAENORHABDITIS ELEGANS; CELL SURVIVAL; CEREBROSPINAL FLUID ANALYSIS; CRYPTOCOCCUS NEOFORMANS; FEMALE; FUNGAL STRAIN; FUNGAL VIRULENCE; GENE DELETION; GENE MUTATION; HUMAN; IN VITRO STUDY; MASS SPECTROMETRY; MENINGITIS; NONHUMAN; PRIORITY JOURNAL; SURVIVAL RATE;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CAENORHABDITIS ELEGANS; CATIONS, MONOVALENT; CATTLE; CELL LINE; CEREBROSPINAL FLUID; CRYPTOCOCCUS NEOFORMANS; DISEASE MODELS, ANIMAL; FUNGAL PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; HUMANS; MACROPHAGES; MENINGITIS, CRYPTOCOCCAL; MICE; MUTATION; OSMOTIC PRESSURE; RABBITS; SERUM; VIRULENCE;

EID: 77957730037     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00551-10     Document Type: Article

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