The fatal fungal outbreak on Vancouver Island is characterized by enhanced intracellular parasitism driven by mitochondrial regulation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 31, 2009, Pages 12980-12985

  Ma, Hansong ^a   Hagen, Ferry ^b,c   Stekel, Dov J ^a   Johnston, Simon A ^a   Sionov, Edward ^d   Falk, Rama ^d   Polacheck, Itzhack ^d   Boekhout, Teun ^b,c   May, Robin C ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b CBS KNAW FUNGAL BIODIVERSITY CENTRE   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Cryptococcus; Macrophage; Vancouver Island outbreak; Virulence

Indexed keywords

ARTICLE; CANADA; COMPARATIVE STUDY; CRYPTOCOCCOSIS; CRYPTOCOCCUS; CRYPTOCOCCUS GATTII; FUNGAL STRAIN; FUNGAL VIRULENCE; FUNGUS ISOLATION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IMMUNE SYSTEM; MACROPHAGE; MAMMAL; MICROARRAY ANALYSIS; MITOCHONDRIAL GENOME; MITOCHONDRION; MYCOSIS; NONHUMAN; PARASITISM; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; UNITED STATES; UPREGULATION; YEAST CELL; ANIMAL; BAGG ALBINO MOUSE; EPIDEMIC; IMMUNOLOGY; MALE; MICROBIOLOGY; MOUSE; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY;

CRYPTOCOCCUS GATTII; MAMMALIA; MURINAE;

VIRULENCE FACTOR;

ANIMALS; CANADA; CRYPTOCOCCOSIS; CRYPTOCOCCUS; DISEASE OUTBREAKS; HUMANS; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MITOCHONDRIA; PHAGOCYTOSIS; VIRULENCE FACTORS;

EID: 69149090138     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0902963106     Document Type: Article

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