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Volumn 28, Issue 3, 2007, Pages 102-107

Tipping the gatekeeper: S1P regulation of endothelial barrier function

Author keywords

[No Author keywords available]

Indexed keywords

ARYLPROPIONIC ACID DERIVATIVE; AUY 954; FINGOLIMOD; G PROTEIN COUPLED RECEPTOR; JTE 013; KRP 203; LIGAND; LYSOPHOSPHOLIPID; RECEPTOR BLOCKING AGENT; SEW 2871; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; UNCLASSIFIED DRUG; VPC 23019; W 123; W 146;

EID: 33847131347     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2007.01.007     Document Type: Article
Times cited : (137)

References (54)
  • 1
    • 0038218405 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate: an enigmatic signalling lipid
    • Spiegel S., and Milstien M. Sphingosine 1-phosphate: an enigmatic signalling lipid. Nat. Rev. Mol. Cell Biol. 4 (2003) 397-407
    • (2003) Nat. Rev. Mol. Cell Biol. , vol.4 , pp. 397-407
    • Spiegel, S.1    Milstien, M.2
  • 2
    • 0037066466 scopus 로고    scopus 로고
    • Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists
    • Mandala S., et al. Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. Science 296 (2002) 346-349
    • (2002) Science , vol.296 , pp. 346-349
    • Mandala, S.1
  • 3
    • 0036303786 scopus 로고    scopus 로고
    • The therapeutic potential of modulating the ceramide/sphingomyelin pathway
    • Kolesnick R. The therapeutic potential of modulating the ceramide/sphingomyelin pathway. J. Clin. Invest. 110 (2002) 3-8
    • (2002) J. Clin. Invest. , vol.110 , pp. 3-8
    • Kolesnick, R.1
  • 4
    • 21844457949 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network
    • Rosen H., and Goetzl E.J. Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network. Nat. Rev. Immunol. 5 (2005) 560-570
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 560-570
    • Rosen, H.1    Goetzl, E.J.2
  • 5
    • 0141566600 scopus 로고    scopus 로고
    • Egress: a receptor-regulated step in lymphocyte trafficking
    • Rosen H., et al. Egress: a receptor-regulated step in lymphocyte trafficking. Immunol. Rev. 195 (2003) 160-177
    • (2003) Immunol. Rev. , vol.195 , pp. 160-177
    • Rosen, H.1
  • 6
    • 0043073128 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate pathway therapeutics: a lipid-receptor paradigm
    • Rosen H., and Liao J. Sphingosine 1-phosphate pathway therapeutics: a lipid-receptor paradigm. Curr. Opin. Chem. Biol. 7 (2003) 461-468
    • (2003) Curr. Opin. Chem. Biol. , vol.7 , pp. 461-468
    • Rosen, H.1    Liao, J.2
  • 7
    • 0034672133 scopus 로고    scopus 로고
    • Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions
    • Murata N., et al. Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions. Biochem. J. 352 (2000) 809-815
    • (2000) Biochem. J. , vol.352 , pp. 809-815
    • Murata, N.1
  • 8
    • 33746365908 scopus 로고    scopus 로고
    • 1 antagonist in vivo
    • 1 antagonist in vivo. Nat. Chem. Biol. 2 (2006) 434-441
    • (2006) Nat. Chem. Biol. , vol.2 , pp. 434-441
    • Sanna, M.G.1
  • 9
    • 11144353922 scopus 로고    scopus 로고
    • 3, respectively, regulate lymphocyte recirculation and heart rate
    • 3, respectively, regulate lymphocyte recirculation and heart rate. J. Biol. Chem. 279 (2004) 13839-13848
    • (2004) J. Biol. Chem. , vol.279 , pp. 13839-13848
    • Sanna, M.G.1
  • 10
    • 11144355672 scopus 로고    scopus 로고
    • Immune cell regulation and cardiovascular effects of sphingosine 1-phosphate receptor agonists in rodents are mediated via distinct receptor subtypes
    • Forrest M., et al. Immune cell regulation and cardiovascular effects of sphingosine 1-phosphate receptor agonists in rodents are mediated via distinct receptor subtypes. J. Pharmacol. Exp. Ther. 309 (2004) 758-768
    • (2004) J. Pharmacol. Exp. Ther. , vol.309 , pp. 758-768
    • Forrest, M.1
  • 11
    • 0037162030 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate receptors and the development of the vascular system
    • Allende M.L., and Proia R.L. Sphingosine-1-phosphate receptors and the development of the vascular system. Biochim. Biophys. Acta 1582 (2002) 222-227
    • (2002) Biochim. Biophys. Acta , vol.1582 , pp. 222-227
    • Allende, M.L.1    Proia, R.L.2
  • 12
    • 0242411518 scopus 로고    scopus 로고
    • 1 acts within endothelial cells to regulate vascular maturation
    • 1 acts within endothelial cells to regulate vascular maturation. Blood 102 (2003) 3665-3667
    • (2003) Blood , vol.102 , pp. 3665-3667
    • Allende, M.L.1
  • 13
    • 30044441314 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses
    • Wei S.H., et al. Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses. Nat. Immunol. 6 (2005) 1228-1235
    • (2005) Nat. Immunol. , vol.6 , pp. 1228-1235
    • Wei, S.H.1
  • 14
    • 33747419124 scopus 로고    scopus 로고
    • Pulmonary and vascular pharmacology of sphingosine 1-phosphate
    • Brinkmann V., and Baumruker T. Pulmonary and vascular pharmacology of sphingosine 1-phosphate. Curr. Opin. Pharmacol. 6 (2006) 244-250
    • (2006) Curr. Opin. Pharmacol. , vol.6 , pp. 244-250
    • Brinkmann, V.1    Baumruker, T.2
  • 15
    • 7044241285 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury
    • McVerry B.J., et al. Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury. Am. J. Respir. Crit. Care Med. 170 (2004) 987-993
    • (2004) Am. J. Respir. Crit. Care Med. , vol.170 , pp. 987-993
    • McVerry, B.J.1
  • 16
    • 5644287793 scopus 로고    scopus 로고
    • In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: mechanistic insights
    • McVerry B.J., and Garcia J. In vitro and in vivo modulation of vascular barrier integrity by sphingosine 1-phosphate: mechanistic insights. Cell. Signal. 17 (2005) 131-139
    • (2005) Cell. Signal. , vol.17 , pp. 131-139
    • McVerry, B.J.1    Garcia, J.2
  • 17
    • 0033783522 scopus 로고    scopus 로고
    • Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
    • Liu Y., et al. Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. J. Clin. Invest. 106 (2000) 951-961
    • (2000) J. Clin. Invest. , vol.106 , pp. 951-961
    • Liu, Y.1
  • 18
    • 28244456527 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate agonists increase macrophage homing, lymphocyte contacts, and endothelial junctional complex formation in murine lymph nodes
    • Singer I.I., et al. Sphingosine-1-phosphate agonists increase macrophage homing, lymphocyte contacts, and endothelial junctional complex formation in murine lymph nodes. J. Immunol. 175 (2005) 7151-7161
    • (2005) J. Immunol. , vol.175 , pp. 7151-7161
    • Singer, I.I.1
  • 19
    • 0344443651 scopus 로고    scopus 로고
    • Phosphorylation and action of the immunomodulator FTY720 inhibits VEGF-induced vascular permeability
    • Sanchez T., et al. Phosphorylation and action of the immunomodulator FTY720 inhibits VEGF-induced vascular permeability. J. Biol. Chem. 278 (2003) 47281-47290
    • (2003) J. Biol. Chem. , vol.278 , pp. 47281-47290
    • Sanchez, T.1
  • 20
    • 13244270031 scopus 로고    scopus 로고
    • Cyclical modulation of sphingosine-1-phosphate receptor 1 surface expression during lymphocyte recirculation and relationship to lymphoid organ transit
    • Lo C.G., et al. Cyclical modulation of sphingosine-1-phosphate receptor 1 surface expression during lymphocyte recirculation and relationship to lymphoid organ transit. J. Exp. Med. 201 (2005) 291-301
    • (2005) J. Exp. Med. , vol.201 , pp. 291-301
    • Lo, C.G.1
  • 21
    • 33746324873 scopus 로고    scopus 로고
    • Lipid-induced phenotypes
    • Schultz C. Lipid-induced phenotypes. Nat. Chem. Biol. 2 (2006) 396-398
    • (2006) Nat. Chem. Biol. , vol.2 , pp. 396-398
    • Schultz, C.1
  • 22
    • 15444373345 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate analogs as receptor antagonists
    • Davis M.D., et al. Sphingosine 1-phosphate analogs as receptor antagonists. J. Biol. Chem. 280 (2005) 9833-9841
    • (2005) J. Biol. Chem. , vol.280 , pp. 9833-9841
    • Davis, M.D.1
  • 23
    • 0034671505 scopus 로고    scopus 로고
    • Identification of Edg1 receptor residues that recognize sphingosine 1-phosphate
    • Parrill A.L., et al. Identification of Edg1 receptor residues that recognize sphingosine 1-phosphate. J. Biol. Chem. 275 (2000) 39379-39384
    • (2000) J. Biol. Chem. , vol.275 , pp. 39379-39384
    • Parrill, A.L.1
  • 24
    • 18444390571 scopus 로고    scopus 로고
    • Molecular basis for the lysophosphatidic acid receptor agonist selectivity
    • Sardar V.M., et al. Molecular basis for the lysophosphatidic acid receptor agonist selectivity. Biochim. Biophys. Acta 1582 (2002) 309-317
    • (2002) Biochim. Biophys. Acta , vol.1582 , pp. 309-317
    • Sardar, V.M.1
  • 25
    • 0035966064 scopus 로고    scopus 로고
    • 1 (EDG1) and LPA1 (EDG2) phospholipid growth factor receptors
    • 1 (EDG1) and LPA1 (EDG2) phospholipid growth factor receptors. J. Biol. Chem. 276 (2001) 49213-49220
    • (2001) J. Biol. Chem. , vol.276 , pp. 49213-49220
    • Wang, D.A.1
  • 26
    • 0037077308 scopus 로고    scopus 로고
    • The immune modulator FTY720 targets sphingosine 1-phosphate receptors
    • Brinkmann V., et al. The immune modulator FTY720 targets sphingosine 1-phosphate receptors. J. Biol. Chem. 277 (2002) 21453-21457
    • (2002) J. Biol. Chem. , vol.277 , pp. 21453-21457
    • Brinkmann, V.1
  • 27
    • 0036773971 scopus 로고    scopus 로고
    • FTY720: targeting G-protein-coupled receptors for S1P in transplantation and autoimmunity
    • Brinkmann V., and Lynch K. FTY720: targeting G-protein-coupled receptors for S1P in transplantation and autoimmunity. Curr. Opin. Immunol. 14 (2002) 569-575
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 569-575
    • Brinkmann, V.1    Lynch, K.2
  • 28
    • 33751093316 scopus 로고    scopus 로고
    • A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model
    • Pan S., et al. A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model. Chem. Biol. 13 (2006) 1227-1234
    • (2006) Chem. Biol. , vol.13 , pp. 1227-1234
    • Pan, S.1
  • 29
    • 33845296479 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of γ-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists
    • Foss F., et al. Synthesis and biological evaluation of γ-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists. Bioorg. Med. Chem. 15 (2007) 663-677
    • (2007) Bioorg. Med. Chem. , vol.15 , pp. 663-677
    • Foss, F.1
  • 31
    • 1642580757 scopus 로고    scopus 로고
    • Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
    • Matloubian M., et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 427 (2004) 355-360
    • (2004) Nature , vol.427 , pp. 355-360
    • Matloubian, M.1
  • 32
    • 24944535833 scopus 로고    scopus 로고
    • 1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate
    • 1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate. Chem. Biol. 12 (2005) 703-715
    • (2005) Chem. Biol. , vol.12 , pp. 703-715
    • Jo, E.1
  • 33
    • 33847154714 scopus 로고    scopus 로고
    • Modulating molecular gateways
    • Owens J. Modulating molecular gateways. Nature Rev. Drug Discov. 5 (2006) 633
    • (2006) Nature Rev. Drug Discov. , vol.5 , pp. 633
    • Owens, J.1
  • 34
    • 2442561611 scopus 로고    scopus 로고
    • 1, on T-cells controls thymic emigration
    • 1, on T-cells controls thymic emigration. J. Biol. Chem. 279 (2004) 15396-15401
    • (2004) J. Biol. Chem. , vol.279 , pp. 15396-15401
    • Allende, M.L.1
  • 35
    • 0141814654 scopus 로고    scopus 로고
    • Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist
    • Rosen H., et al. Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 10907-10912
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 10907-10912
    • Rosen, H.1
  • 36
    • 0034105487 scopus 로고    scopus 로고
    • Immunosuppressant FTY720 inhibits thymocyte emigration
    • Yagi H., et al. Immunosuppressant FTY720 inhibits thymocyte emigration. Eur. J. Immunol. 2000 (2000) 1435-1444
    • (2000) Eur. J. Immunol. , vol.2000 , pp. 1435-1444
    • Yagi, H.1
  • 37
    • 0035988219 scopus 로고    scopus 로고
    • A potential role for CD69 in thymocyte emigration
    • Feng C., et al. A potential role for CD69 in thymocyte emigration. Int. Immunol. 14 (2002) 535-544
    • (2002) Int. Immunol. , vol.14 , pp. 535-544
    • Feng, C.1
  • 38
    • 0036134843 scopus 로고    scopus 로고
    • The generation of mature, single-positive thymocytes in vivo is dysregulated by CD69 blockade or overexpression
    • Nakayama T., et al. The generation of mature, single-positive thymocytes in vivo is dysregulated by CD69 blockade or overexpression. J. Immunol. 168 (2002) 87-94
    • (2002) J. Immunol. , vol.168 , pp. 87-94
    • Nakayama, T.1
  • 39
    • 33645289121 scopus 로고    scopus 로고
    • 1 and lymphocyte egress from lymphoid organs
    • 1 and lymphocyte egress from lymphoid organs. Nature 440 (2006) 540-544
    • (2006) Nature , vol.440 , pp. 540-544
    • Shiow, L.R.1
  • 40
    • 0037036142 scopus 로고    scopus 로고
    • Two-photon imaging of lymphocyte motility and antigen response in intact lymph node
    • Miller M.J., et al. Two-photon imaging of lymphocyte motility and antigen response in intact lymph node. Science 296 (2002) 1869-1873
    • (2002) Science , vol.296 , pp. 1869-1873
    • Miller, M.J.1
  • 41
    • 0141566612 scopus 로고    scopus 로고
    • A stochastic view of lymphocyte motility and trafficking within the lymph node
    • Wei S.H., et al. A stochastic view of lymphocyte motility and trafficking within the lymph node. Immunol. Rev. 195 (2003) 136-159
    • (2003) Immunol. Rev. , vol.195 , pp. 136-159
    • Wei, S.H.1
  • 42
    • 33744460736 scopus 로고    scopus 로고
    • Role of β-adrenergic receptor signaling and desensitization in heart failure: new concepts and prospects for treatment
    • Tilley D.G., and Rockman H. Role of β-adrenergic receptor signaling and desensitization in heart failure: new concepts and prospects for treatment. Expert Rev. Cardiovasc. Ther. 4 (2006) 417-432
    • (2006) Expert Rev. Cardiovasc. Ther. , vol.4 , pp. 417-432
    • Tilley, D.G.1    Rockman, H.2
  • 43
    • 0036035993 scopus 로고    scopus 로고
    • The roles of sphingosine-1-phosphate in asthma
    • Jolly P.S., et al. The roles of sphingosine-1-phosphate in asthma. Mol. Immunol. 38 (2002) 1239-1245
    • (2002) Mol. Immunol. , vol.38 , pp. 1239-1245
    • Jolly, P.S.1
  • 44
    • 33645099042 scopus 로고    scopus 로고
    • The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2a receptor
    • Milojevic T., et al. The ubiquitin-specific protease Usp4 regulates the cell surface level of the A2a receptor. Mol. Pharmacol. 69 (2006) 1083-1094
    • (2006) Mol. Pharmacol. , vol.69 , pp. 1083-1094
    • Milojevic, T.1
  • 45
    • 30044447860 scopus 로고    scopus 로고
    • 1D-adrenergic receptors form a single functional entity
    • 1D-adrenergic receptors form a single functional entity. Mol. Pharmacol. 69 (2006) 45-55
    • (2006) Mol. Pharmacol. , vol.69 , pp. 45-55
    • Hague, C.1
  • 46
    • 28444464430 scopus 로고    scopus 로고
    • GPCR modulation by RAMPs
    • Hay D.L., et al. GPCR modulation by RAMPs. Pharmacol. Ther. 109 (2006) 173-197
    • (2006) Pharmacol. Ther. , vol.109 , pp. 173-197
    • Hay, D.L.1
  • 47
    • 33644861545 scopus 로고    scopus 로고
    • Lysophospholipid receptors as potential drug targets in tissue transplantation and autoimmune diseases
    • Chun J., and Rosen H. Lysophospholipid receptors as potential drug targets in tissue transplantation and autoimmune diseases. Curr. Pharm. Des. 12 (2006) 161-171
    • (2006) Curr. Pharm. Des. , vol.12 , pp. 161-171
    • Chun, J.1    Rosen, H.2
  • 48
    • 33746514475 scopus 로고    scopus 로고
    • 1) with high selectivity against all other known S1P receptor subtypes
    • 1) with high selectivity against all other known S1P receptor subtypes. Bioorg. Med. Chem. Lett. 16 (2006) 3679-3683
    • (2006) Bioorg. Med. Chem. Lett. , vol.16 , pp. 3679-3683
    • Yan, L.1
  • 49
    • 19944432761 scopus 로고    scopus 로고
    • KRP-203, a novel synthetic immunosuppressant, prolongs graft survival and attenuates chronic rejection in rat skin and heart allografts
    • Shimizu H., et al. KRP-203, a novel synthetic immunosuppressant, prolongs graft survival and attenuates chronic rejection in rat skin and heart allografts. Circulation 111 (2005) 222-229
    • (2005) Circulation , vol.111 , pp. 222-229
    • Shimizu, H.1
  • 50
    • 0036434445 scopus 로고    scopus 로고
    • Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist
    • Osada M., et al. Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist. Biochem. Biophys. Res. Commun. 299 (2002) 483-487
    • (2002) Biochem. Biophys. Res. Commun. , vol.299 , pp. 483-487
    • Osada, M.1
  • 51
    • 0034887535 scopus 로고    scopus 로고
    • B2 sphingosine 1-phosphate receptor in neuronal excitability
    • B2 sphingosine 1-phosphate receptor in neuronal excitability. Eur. J. Neurosci. 14 (2001) 203-209
    • (2001) Eur. J. Neurosci. , vol.14 , pp. 203-209
    • MacLennan, A.J.1
  • 52
    • 33748310612 scopus 로고    scopus 로고
    • 2 sphingosine 1-phosphate receptor is essential for auditory and vestibular function
    • 2 sphingosine 1-phosphate receptor is essential for auditory and vestibular function. Hear. Res. 220 (2006) 38-48
    • (2006) Hear. Res. , vol.220 , pp. 38-48
    • MacLennan, A.J.1
  • 53
    • 0037067769 scopus 로고    scopus 로고
    • B3/EDG-3
    • B3/EDG-3. J. Biol. Chem. 277 (2002) 25152-25159
    • (2002) J. Biol. Chem. , vol.277 , pp. 25152-25159
    • Ishii, I.1
  • 54
    • 33847113358 scopus 로고    scopus 로고
    • Gonzalez-Cabrera, P.J. et al. Mapping pathways downstream of S1P1 by differential chemical perturbation and proteomics. J. Biol. Chem. (in press)


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