Identification of granulocyte colony-stimulating factor and interleukin-6 as candidate biomarkers of CBLB502 efficacy as a medical radiation countermeasure

Journal of Pharmacology and Experimental Therapeutics

Volumn 343, Issue 2, 2012, Pages 497-508

  Krivokrysenko, Vadim I ^a   Shakhov, Alexander N ^a   Singh, Vijay K ^b,c   Bone, Frederick ^a   Kononov, Yevgeniy ^a   Shyshynova, Inna ^a   Cheney, Alec ^a   Maitra, Ratan K ^a   Purmal, Andrei ^a   Whitnall, Mark H ^c   Gudkov, Andrei V ^a,d   Feinstein, Elena ^a  

^a CLEVELAND BIOLABS INC   (United States)

^b Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

^c UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^d ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CBLB 502; CYTOKINE; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 6; RADIOPROTECTIVE AGENT; TOLL LIKE RECEPTOR 5; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; FEMALE; IRRADIATION; MALE; MAMMAL; MOUSE; NONHUMAN; PRIMATE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INDUCTION; RADIATION PROTECTION; RADIATION RESPONSE; SINGLE DRUG DOSE;

ANIMALS; AREA UNDER CURVE; BIOLOGICAL MARKERS; CYTOKINES; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; GRANULOCYTE COLONY-STIMULATING FACTOR; HUMANS; INJECTIONS, INTRAMUSCULAR; INTERLEUKIN-6; KAPLAN-MEIER ESTIMATE; MACACA MULATTA; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; PEPTIDES; SPECIES SPECIFICITY; WHOLE-BODY IRRADIATION;

EID: 84867594290     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.196071     Document Type: Article

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