메뉴 건너뛰기




Volumn 7, Issue 4, 2007, Pages 500-505

5-androstenediol improves survival in clinically unsupported rhesus monkeys with radiation-induced myelosuppression

Author keywords

Acute radiation syndrome; AED; Androstenediol; Hematopoiesis; Radiation protection; Rhesus macaques

Indexed keywords

ANDROSTENEDIOL; ANTIBIOTIC AGENT;

EID: 33847073425     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2006.12.005     Document Type: Article
Times cited : (71)

References (34)
  • 1
    • 1542373521 scopus 로고    scopus 로고
    • Medical response to radiation incidents and radionuclear threats
    • Turai I., Veress K., Gunalp B., and Souchkevitch G. Medical response to radiation incidents and radionuclear threats. BMJ 328 (2004) 568-572
    • (2004) BMJ , vol.328 , pp. 568-572
    • Turai, I.1    Veress, K.2    Gunalp, B.3    Souchkevitch, G.4
  • 2
    • 0034728873 scopus 로고    scopus 로고
    • Nuclear weapons, a continuing threat to health
    • Holdstock D., and Waterston L. Nuclear weapons, a continuing threat to health. Lancet 355 (2000) 1544-1547
    • (2000) Lancet , vol.355 , pp. 1544-1547
    • Holdstock, D.1    Waterston, L.2
  • 4
    • 20244382799 scopus 로고    scopus 로고
    • Medical management of the acute radiation syndrome: recommendations of the Strategic National Stockpile Radiation Working Group
    • Waselenko J.K., MacVittie T.J., Blakely W.F., Pesik N., Wiley A.L., Dickerson W.E., et al. Medical management of the acute radiation syndrome: recommendations of the Strategic National Stockpile Radiation Working Group. Ann Intern Med 140 (2004) 1037-1051
    • (2004) Ann Intern Med , vol.140 , pp. 1037-1051
    • Waselenko, J.K.1    MacVittie, T.J.2    Blakely, W.F.3    Pesik, N.4    Wiley, A.L.5    Dickerson, W.E.6
  • 5
    • 85069067690 scopus 로고    scopus 로고
    • Code of Federal Regulations title 21 food and drugs. Part 314 - subpart I - approval of new drugs when human efficacy studies are not ethical or feasible
    • U.S. Govt. Print. Off., Washington
    • Code of Federal Regulations title 21 food and drugs. Part 314 - subpart I - approval of new drugs when human efficacy studies are not ethical or feasible. Code of Federal Regulations (2005), U.S. Govt. Print. Off., Washington 166-169
    • (2005) Code of Federal Regulations , pp. 166-169
  • 7
    • 0034868707 scopus 로고    scopus 로고
    • In vivo radioprotection by 5-androstenediol: stimulation of the innate immune system
    • Whitnall M.H., Inal C.E., Jackson III W.E., Miner V.L., Villa V., and Seed T.M. In vivo radioprotection by 5-androstenediol: stimulation of the innate immune system. Radiat Res 156 (2001) 283-293
    • (2001) Radiat Res , vol.156 , pp. 283-293
    • Whitnall, M.H.1    Inal, C.E.2    Jackson III, W.E.3    Miner, V.L.4    Villa, V.5    Seed, T.M.6
  • 11
    • 33748591080 scopus 로고    scopus 로고
    • 5-androstenediol stimulates multilineage hematopoiesis in rhesus monkeys with radiation-induced myelosuppression
    • Stickney D.R., Dowding C., Garsd A., Ahlem C., Whitnall M., McKeon M., et al. 5-androstenediol stimulates multilineage hematopoiesis in rhesus monkeys with radiation-induced myelosuppression. Int Immunopharmacol 6 (2006) 1706-1713
    • (2006) Int Immunopharmacol , vol.6 , pp. 1706-1713
    • Stickney, D.R.1    Dowding, C.2    Garsd, A.3    Ahlem, C.4    Whitnall, M.5    McKeon, M.6
  • 13
    • 85069060460 scopus 로고    scopus 로고
    • Code of Federal Regulations title 21 food and drugs. Part 58 good laboratory practice for nonclinical laboratory studies
    • U.S. Govt. Print. Off., Washington, D. C.
    • Code of Federal Regulations title 21 food and drugs. Part 58 good laboratory practice for nonclinical laboratory studies. Code of Federal Regulations (2005), U.S. Govt. Print. Off., Washington, D. C. 300-314
    • (2005) Code of Federal Regulations , pp. 300-314
  • 14
    • 85069073353 scopus 로고    scopus 로고
    • Jackson III WE. Literature estimates and calibration studies of the total body irradiation dose to achieve 50% mortality in primates. Unpublished data from James R. Eltringham, MD via Thomas J. MacVittie, MD. (Data on file). In: Garsd A, Stickney DR, editors. Bethesda, MD; 2004.
  • 15
    • 0032874911 scopus 로고    scopus 로고
    • AAPM's TG-51 protocol for clinical reference dosimetry of high-energy photon and electron beams
    • Almond P.R., Biggs P.J., Coursey B.M., Hanson W.F., Huq M.S., Nath R., et al. AAPM's TG-51 protocol for clinical reference dosimetry of high-energy photon and electron beams. Med Phys 26 (1999) 1847-1870
    • (1999) Med Phys , vol.26 , pp. 1847-1870
    • Almond, P.R.1    Biggs, P.J.2    Coursey, B.M.3    Hanson, W.F.4    Huq, M.S.5    Nath, R.6
  • 18
    • 85069080306 scopus 로고    scopus 로고
    • Agresti A. Small-sample conditional inference for linear logit model. Categorical data analysis. 2nd ed. New York: John Wiley & Sons, Inc., 2002. pp 151-153; 181; 253.
  • 19
    • 85069067567 scopus 로고    scopus 로고
    • BLA no. 125031, approval history
    • NEULASTA™ (Pegfilgrastim), FDA, Office of Oncology Drug Products, Silver Springs, MD
    • Gootenberg J.E., and NEULASTA™ (Pegfilgrastim). BLA no. 125031, approval history. Medical officer clinical review of BLA STN 125031. Part 1 of 3 (2002), FDA, Office of Oncology Drug Products, Silver Springs, MD 1-42
    • (2002) Medical officer clinical review of BLA STN 125031. Part 1 of 3 , pp. 1-42
    • Gootenberg, J.E.1
  • 20
    • 85069059510 scopus 로고    scopus 로고
    • In a conversation with D.D. Leavitt, Ph.D. (July 2006). Isodose measurements and beam characteristics of cobalt-60 photons and 6 MV X-rays with 1 cm beam modifier externally superimposed.
  • 22
    • 0031701077 scopus 로고    scopus 로고
    • Radiation-induced genomic instability in haemopoietic cells
    • Wright E.G. Radiation-induced genomic instability in haemopoietic cells. Int J Radiat Biol 74 (1998) 681-687
    • (1998) Int J Radiat Biol , vol.74 , pp. 681-687
    • Wright, E.G.1
  • 23
    • 0037250171 scopus 로고    scopus 로고
    • Radiation-induced genomic instability and bystander effects: related inflammatory-type responses to radiation-induced stress and injury? A review
    • Lorimore S.A., and Wright E.G. Radiation-induced genomic instability and bystander effects: related inflammatory-type responses to radiation-induced stress and injury? A review. Int J Radiat Biol 79 (2003) 15-25
    • (2003) Int J Radiat Biol , vol.79 , pp. 15-25
    • Lorimore, S.A.1    Wright, E.G.2
  • 24
    • 33748584910 scopus 로고    scopus 로고
    • HE2100 (5-androstene-3 beta, 17 beta-diol) after cytoreductive total body irradiation of rhesus monkeys promotes the recovery of immature CD34+ bone marrow cells; accelerates platelet, granulocyte and red cell reconstitution, and alleviates neutropenia and anemia
    • [Abstract #4203]
    • Kaya-Aerts F.S.F., Visser T.P., Reading C.L., Frincke J.M., Verstegen M.M.A., Stickney D.R., et al. HE2100 (5-androstene-3 beta, 17 beta-diol) after cytoreductive total body irradiation of rhesus monkeys promotes the recovery of immature CD34+ bone marrow cells; accelerates platelet, granulocyte and red cell reconstitution, and alleviates neutropenia and anemia. Blood 106 (2005) 131b [Abstract #4203]
    • (2005) Blood , vol.106
    • Kaya-Aerts, F.S.F.1    Visser, T.P.2    Reading, C.L.3    Frincke, J.M.4    Verstegen, M.M.A.5    Stickney, D.R.6
  • 25
    • 0013877409 scopus 로고
    • Quantitative relationships between circulating leukocytes and infection in patients with acute leukemia
    • Bodey G.P., Buckley M., Sathe Y.S., and Freireich E.J. Quantitative relationships between circulating leukocytes and infection in patients with acute leukemia. Ann Intern Med 64 (1966) 328-340
    • (1966) Ann Intern Med , vol.64 , pp. 328-340
    • Bodey, G.P.1    Buckley, M.2    Sathe, Y.S.3    Freireich, E.J.4
  • 26
    • 0025800331 scopus 로고
    • Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer
    • Crawford J., Ozer H., Stoller R., Johnson D., Lyman G., Tabbara I., et al. Reduction by granulocyte colony-stimulating factor of fever and neutropenia induced by chemotherapy in patients with small-cell lung cancer. N Engl J Med 325 (1991) 164-170
    • (1991) N Engl J Med , vol.325 , pp. 164-170
    • Crawford, J.1    Ozer, H.2    Stoller, R.3    Johnson, D.4    Lyman, G.5    Tabbara, I.6
  • 27
    • 0036396275 scopus 로고    scopus 로고
    • Role of blood platelets in infection and inflammation
    • Klinger M.H., and Jelkmann W. Role of blood platelets in infection and inflammation. J Interferon Cytokine Res 22 (2002) 913-922
    • (2002) J Interferon Cytokine Res , vol.22 , pp. 913-922
    • Klinger, M.H.1    Jelkmann, W.2
  • 28
    • 0015159521 scopus 로고
    • Rabbit platelet bactericidal protein
    • Weksler B.B., and Nachman R.L. Rabbit platelet bactericidal protein. J Exp Med 134 (1971) 1114-1130
    • (1971) J Exp Med , vol.134 , pp. 1114-1130
    • Weksler, B.B.1    Nachman, R.L.2
  • 29
    • 0026523731 scopus 로고
    • Partial characterization and staphylocidal activity of thrombin-induced platelet microbicidal protein
    • Yeaman M.R., Puentes S.M., Norman D.C., and Bayer A.S. Partial characterization and staphylocidal activity of thrombin-induced platelet microbicidal protein. Infect Immun 60 (1992) 1202-1209
    • (1992) Infect Immun , vol.60 , pp. 1202-1209
    • Yeaman, M.R.1    Puentes, S.M.2    Norman, D.C.3    Bayer, A.S.4
  • 30
    • 0015152169 scopus 로고
    • Platelet interaction with bacteria. II. Fate of the bacteria
    • Clawson C.C., and White J.G. Platelet interaction with bacteria. II. Fate of the bacteria. Am J Pathol 65 (1971) 381-397
    • (1971) Am J Pathol , vol.65 , pp. 381-397
    • Clawson, C.C.1    White, J.G.2
  • 31
    • 0002588198 scopus 로고
    • Comparative bactericidal activities of blood serum and plasma serum
    • Hirsch J.G. Comparative bactericidal activities of blood serum and plasma serum. J Exp Med 112 (1960) 15-22
    • (1960) J Exp Med , vol.112 , pp. 15-22
    • Hirsch, J.G.1
  • 32
    • 0017260905 scopus 로고
    • On physiological microthromboembolization as the primary platelet function: elimination of invaded particles from the circulation and its pathogenic significance
    • Copley A.L., and Witte S. On physiological microthromboembolization as the primary platelet function: elimination of invaded particles from the circulation and its pathogenic significance. Thromb Res 8 (1976) 251-262
    • (1976) Thromb Res , vol.8 , pp. 251-262
    • Copley, A.L.1    Witte, S.2
  • 33
    • 0029739334 scopus 로고    scopus 로고
    • Staphylocidal action of thrombin-induced platelet microbicidal protein is influenced by microenvironment and target cell growth phase
    • Koo S.P., Yeaman M.R., and Bayer A.S. Staphylocidal action of thrombin-induced platelet microbicidal protein is influenced by microenvironment and target cell growth phase. Infect Immun 64 (1996) 3758-3764
    • (1996) Infect Immun , vol.64 , pp. 3758-3764
    • Koo, S.P.1    Yeaman, M.R.2    Bayer, A.S.3
  • 34
    • 0033022973 scopus 로고    scopus 로고
    • Antimicrobial peptides from platelets
    • Yeaman M.R., and Bayer A.S. Antimicrobial peptides from platelets. Drug Resist Updat 2 (1999) 116-126
    • (1999) Drug Resist Updat , vol.2 , pp. 116-126
    • Yeaman, M.R.1    Bayer, A.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.