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Volumn 4, Issue 1, 2011, Pages 102-111

TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage

Author keywords

[No Author keywords available]

Indexed keywords

FLAGELLIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; TOLL LIKE RECEPTOR 5;

EID: 78649545020     PISSN: 19330219     EISSN: None     Source Type: Journal    
DOI: 10.1038/mi.2010.57     Document Type: Article
Times cited : (68)

References (43)
  • 1
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira, S., Uematsu, S. & Takeuchi, O. Pathogen recognition and innate immunity. Cell 124, 783-801 (2006).
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 2
    • 66749174867 scopus 로고    scopus 로고
    • The infl ammasomes: Guardians of the body
    • Martinon, F., Mayor, A. & Tschopp, J. The infl ammasomes: Guardians of the body. Annu. Rev. Immunol. 27, 229-265 (2009).
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 229-265
    • Martinon, F.1    Mayor, A.2    Tschopp, J.3
  • 3
    • 33744493091 scopus 로고    scopus 로고
    • Cytoplasmic fl agellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
    • Miao, E. A. et al. Cytoplasmic fl agellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat. Immunol. 7, 569-575 (2006).
    • (2006) Nat. Immunol. , vol.7 , pp. 569-575
    • Miao, E.A.1
  • 4
    • 33744464740 scopus 로고    scopus 로고
    • Cytosolic fl agellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
    • Franchi, L. et al. Cytosolic fl agellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat. Immunol. 7, 576-582 (2006).
    • (2006) Nat. Immunol. , vol.7 , pp. 576-582
    • Franchi, L.1
  • 5
    • 52549099416 scopus 로고    scopus 로고
    • Critical function for Naip5 in infl ammasome activation by a conserved carboxy-terminal domain of fl agellin
    • Lightfi eld, K. L. et al. Critical function for Naip5 in infl ammasome activation by a conserved carboxy-terminal domain of fl agellin. Nat. Immunol. 9, 1171-1178 (2008).
    • (2008) Nat. Immunol. , vol.9 , pp. 1171-1178
    • Lightfi Eld, K.L.1
  • 6
    • 0038222345 scopus 로고    scopus 로고
    • The Toll-like receptor 5 stimulus bacterial fl agellin induces maturation and chemokine production in human dendritic cells
    • Means, T. K., Hayashi, F., Smith, K. D., Aderem, A. & Luster, A. D. The Toll-like receptor 5 stimulus bacterial fl agellin induces maturation and chemokine production in human dendritic cells. J. Immunol. 170, 5165-5175 (2003).
    • (2003) J. Immunol. , vol.170 , pp. 5165-5175
    • Means, T.K.1    Hayashi, F.2    Smith, K.D.3    Aderem, A.4    Luster, A.D.5
  • 7
    • 34248385381 scopus 로고    scopus 로고
    • Flagellin suppresses epithelial apoptosis and limits disease during enteric infection
    • Vijay-Kumar, M. et al. Flagellin suppresses epithelial apoptosis and limits disease during enteric infection. Am. J. Pathol. 169, 1686-1700 (2006).
    • (2006) Am. J. Pathol. , vol.169 , pp. 1686-1700
    • Vijay-Kumar, M.1
  • 8
    • 34848866958 scopus 로고    scopus 로고
    • Pyroptosis and host cell death responses during Salmonella infection
    • Fink, S. L. & Cookson, B. T. Pyroptosis and host cell death responses during Salmonella infection. Cell Microbiol. 9, 2562-2570 (2007).
    • (2007) Cell Microbiol. , vol.9 , pp. 2562-2570
    • Fink, S.L.1    Cookson, B.T.2
  • 9
    • 66649121678 scopus 로고    scopus 로고
    • An autoinfl ammatory disease with defi ciency of the interleukin-1- receptor antagonist
    • Aksentijevich, I. et al. An autoinfl ammatory disease with defi ciency of the interleukin-1-receptor antagonist. N Engl. J. Med. 360, 2426-2437 (2009).
    • (2009) N Engl. J. Med. , vol.360 , pp. 2426-2437
    • Aksentijevich, I.1
  • 11
    • 14044273004 scopus 로고    scopus 로고
    • The production of IL-1 receptor antagonist in IFN-beta-stimulated human monocytes depends on the activation of phosphatidylinositol 3-kinase but not of STAT1
    • Molnarfi, N., Hyka-Nouspikel, N., Gruaz, L., Dayer, J. M. & Burger, D. The production of IL-1 receptor antagonist in IFN-beta-stimulated human monocytes depends on the activation of phosphatidylinositol 3-kinase but not of STAT1. J. Immunol. 174, 2974-2980 (2005).
    • (2005) J. Immunol. , vol.174 , pp. 2974-2980
    • Molnarfi, N.1    Hyka-Nouspikel, N.2    Gruaz, L.3    Dayer, J.M.4    Burger, D.5
  • 12
    • 0029768091 scopus 로고    scopus 로고
    • Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice
    • Hirsch, E., Irikura, V. M., Paul, S. M. & Hirsh, D. Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice. Proc. Natl. Acad. Sci. USA 93, 11008-11013 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11008-11013
    • Hirsch, E.1    Irikura, V.M.2    Paul, S.M.3    Hirsh, D.4
  • 13
    • 0036644331 scopus 로고    scopus 로고
    • The epistatic interrelationships of IL-1, IL-1 receptor antagonist, and the type I IL-1 receptor
    • Irikura, V. M., Lagraoui, M. & Hirsh, D. The epistatic interrelationships of IL-1, IL-1 receptor antagonist, and the type I IL-1 receptor. J. Immunol. 169, 393-398 (2002).
    • (2002) J. Immunol. , vol.169 , pp. 393-398
    • Irikura, V.M.1    Lagraoui, M.2    Hirsh, D.3
  • 14
    • 0033003709 scopus 로고    scopus 로고
    • Effects of interleukin-1 receptor antagonist overexpression on infection by Listeria monocytogenes
    • Irikura, V. M., Hirsch, E. & Hirsh, D. Effects of interleukin-1 receptor antagonist overexpression on infection by Listeria monocytogenes. Infect. Immun. 67, 1901-1909 (1999).
    • (1999) Infect. Immun. , vol.67 , pp. 1901-1909
    • Irikura, V.M.1    Hirsch, E.2    Hirsh, D.3
  • 15
    • 36849000520 scopus 로고    scopus 로고
    • Deletion of TLR5 results in spontaneous colitis in mice
    • Vijay-Kumar, M. et al. Deletion of TLR5 results in spontaneous colitis in mice. J. Clin. Invest. 117, 3909-3921 (2007).
    • (2007) J. Clin. Invest. , vol.117 , pp. 3909-3921
    • Vijay-Kumar, M.1
  • 16
    • 40749097296 scopus 로고    scopus 로고
    • Toll-like receptor 5-defi cient mice have dysregulated intestinal gene expression and nonspecifi c resistance to Salmonellainduced typhoid-like disease
    • Vijay-Kumar, M. et al. Toll-like receptor 5-defi cient mice have dysregulated intestinal gene expression and nonspecifi c resistance to Salmonellainduced typhoid-like disease. Infect. Immun. 76, 1276-1281 (2008).
    • (2008) Infect. Immun. , vol.76 , pp. 1276-1281
    • Vijay-Kumar, M.1
  • 17
    • 60749119489 scopus 로고    scopus 로고
    • Induction of adaptive immunity by fl agellin does not require robust activation of innate immunity
    • Sanders, C. J. et al. Induction of adaptive immunity by fl agellin does not require robust activation of innate immunity. Eur. J. Immunol. 39, 359-371 (2009).
    • (2009) Eur. J. Immunol. , vol.39 , pp. 359-371
    • Sanders, C.J.1
  • 19
    • 0034024969 scopus 로고    scopus 로고
    • Human intestinal epithelial cells secrete interleukin-1 receptor antagonist and interleukin-8 but not interleukin-1 or interleukin-6
    • Daig, R. et al. Human intestinal epithelial cells secrete interleukin-1 receptor antagonist and interleukin-8 but not interleukin-1 or interleukin-6. Gut 46, 350-358 (2000).
    • (2000) Gut , vol.46 , pp. 350-358
    • Daig, R.1
  • 20
    • 0035881675 scopus 로고    scopus 로고
    • Cutting edge: Bacterial fl agellin activates basolaterally expressed TLR5 to induce epithelial proinfl ammatory gene expression
    • Gewirtz, A. T., Navas, T. A., Lyons, S., Godowski, P. J. & Madara, J. L. Cutting edge: Bacterial fl agellin activates basolaterally expressed TLR5 to induce epithelial proinfl ammatory gene expression. J. Immunol. 167, 1882-1885 (2001).
    • (2001) J. Immunol. , vol.167 , pp. 1882-1885
    • Gewirtz, A.T.1    Navas, T.A.2    Lyons, S.3    Godowski, P.J.4    Madara, J.L.5
  • 21
    • 1842782996 scopus 로고    scopus 로고
    • Anti-infl ammatory properties of pro-infl ammatory interferon-gamma
    • Muhl, H. & Pfeilschifter, J. Anti-infl ammatory properties of pro-infl ammatory interferon-gamma. Int. Immunopharmacol. 3, 1247-1255 (2003).
    • (2003) Int. Immunopharmacol. , vol.3 , pp. 1247-1255
    • Muhl, H.1    Pfeilschifter, J.2
  • 22
    • 0035892991 scopus 로고    scopus 로고
    • Expression and release of IL-18 binding protein in response to IFN-gamma
    • Paulukat, J. et al. Expression and release of IL-18 binding protein in response to IFN-gamma. J. Immunol. 167, 7038-7043 (2001).
    • (2001) J. Immunol. , vol.167 , pp. 7038-7043
    • Paulukat, J.1
  • 23
    • 0038442102 scopus 로고    scopus 로고
    • TLR5-mediated activation of p38 MAPK regulates epithelial IL-8 expression via posttranscriptional mechanism
    • Yu, Y. et al. TLR5-mediated activation of p38 MAPK regulates epithelial IL-8 expression via posttranscriptional mechanism. Am. J. Physiol. Gastrointest. Liver Physiol. 285, G282-G290 (2003).
    • (2003) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.285
    • Yu, Y.1
  • 24
    • 0033989283 scopus 로고    scopus 로고
    • Salmonella typhimurium induces epithelial IL-8 expression via Ca(2+)-mediated activation of the NF-kappaB pathway
    • Gewirtz, A. T. et al. Salmonella typhimurium induces epithelial IL-8 expression via Ca(2+)-mediated activation of the NF-kappaB pathway. J. Clin. Invest. 105, 79-92 (2000).
    • (2000) J. Clin. Invest. , vol.105 , pp. 79-92
    • Gewirtz, A.T.1
  • 25
    • 33746161021 scopus 로고    scopus 로고
    • Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells
    • Uematsu, S. et al. Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells. Nat. Immunol. 7, 868-874 (2006).
    • (2006) Nat. Immunol. , vol.7 , pp. 868-874
    • Uematsu, S.1
  • 26
    • 0028898529 scopus 로고
    • Mucosal imbalance of IL-1 and IL-1 receptor antagonist in infl ammatory bowel disease. A novel mechanism of chronic intestinal infl ammation
    • Casini-Raggi, V. et al. Mucosal imbalance of IL-1 and IL-1 receptor antagonist in infl ammatory bowel disease. A novel mechanism of chronic intestinal infl ammation. J. Immunol. 154, 2434-2440 (1995).
    • (1995) J. Immunol. , vol.154 , pp. 2434-2440
    • Casini-Raggi, V.1
  • 27
    • 47249095741 scopus 로고    scopus 로고
    • Both radioresistant and hemopoietic cells promote innate and adaptive immune responses to fl agellin
    • Sanders, C. J., Moore, D. A. III, Williams, I. R. & Gewirtz, A. T. Both radioresistant and hemopoietic cells promote innate and adaptive immune responses to fl agellin. J. Immunol. 180, 7184-7192 (2008).
    • (2008) J. Immunol. , vol.180 , pp. 7184-7192
    • Sanders, C.J.1    Moore III, D.A.2    Williams, I.R.3    Gewirtz, A.T.4
  • 28
    • 69049118140 scopus 로고    scopus 로고
    • Toll-like receptor 5-dependent regulation of infl ammation in systemic Salmonella enterica Serovar typhimurium infection
    • Fournier, B., Williams, I. R., Gewirtz, A. T. & Neish, A. S. Toll-like receptor 5-dependent regulation of infl ammation in systemic Salmonella enterica Serovar typhimurium infection. Infect. Immun. 77, 4121-4129 (2009).
    • (2009) Infect. Immun. , vol.77 , pp. 4121-4129
    • Fournier, B.1    Williams, I.R.2    Gewirtz, A.T.3    Neish, A.S.4
  • 29
    • 0034874499 scopus 로고    scopus 로고
    • Absence of all components of the fl agellar export and synthesis machinery differentially alters virulence of Salmonella enterica serovar Typhimurium in models of typhoid fever, survival in macrophages, tissue culture invasiveness, and calf enterocolitis
    • Schmitt, C. K. et al. Absence of all components of the fl agellar export and synthesis machinery differentially alters virulence of Salmonella enterica serovar Typhimurium in models of typhoid fever, survival in macrophages, tissue culture invasiveness, and calf enterocolitis. Infect. Immun. 69, 5619-5625 (2001).
    • (2001) Infect. Immun. , vol.69 , pp. 5619-5625
    • Schmitt, C.K.1
  • 30
    • 0029979369 scopus 로고    scopus 로고
    • Biologic basis for interleukin-1 in disease
    • Dinarello, C. A. Biologic basis for interleukin-1 in disease. Blood 87, 2095-2147 (1996).
    • (1996) Blood , vol.87 , pp. 2095-2147
    • Dinarello, C.A.1
  • 31
    • 85185097432 scopus 로고    scopus 로고
    • Interleukin-1beta (IL-1beta) processing pathway
    • cm2
    • Weber, A., Wasiliew, P. & Kracht, M. Interleukin-1beta (IL-1beta) processing pathway. Sci. Signal 3, cm2.
    • Sci. Signal , vol.3
    • Weber, A.1    Wasiliew, P.2    Kracht, M.3
  • 32
    • 0036694645 scopus 로고    scopus 로고
    • The balance between IL-1 and IL-1Ra in disease
    • Arend, W. P. The balance between IL-1 and IL-1Ra in disease. Cytokine Growth Factor Rev. 13, 323-340 (2002).
    • (2002) Cytokine Growth Factor Rev. , vol.13 , pp. 323-340
    • Arend, W.P.1
  • 33
    • 0034618862 scopus 로고    scopus 로고
    • The role of the interleukin-1-receptor antagonist in blocking infl ammation mediated by interleukin-1
    • Dinarello, C. A. The role of the interleukin-1-receptor antagonist in blocking infl ammation mediated by interleukin-1. N Engl. J. Med. 343, 732-734 (2000).
    • (2000) N Engl. J. Med. , vol.343 , pp. 732-734
    • Dinarello, C.A.1
  • 34
    • 0027501020 scopus 로고
    • Interleukin-1 receptor antagonist
    • Arend, W. P. Interleukin-1 receptor antagonist. Adv. Immunol. 54, 167-227 (1993).
    • (1993) Adv. Immunol. , vol.54 , pp. 167-227
    • Arend, W.P.1
  • 35
    • 77951628300 scopus 로고    scopus 로고
    • Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo
    • Mayer-Barber, K. D. et al. Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo. J. Immunol. 184, 3326-3330.
    • J. Immunol. , vol.184 , pp. 3326-3330
    • Mayer-Barber, K.D.1
  • 36
    • 77149142027 scopus 로고    scopus 로고
    • TLR5 is not required for fl agellin-mediated exacerbation of DSS colitis
    • Ivison, S. M. et al. TLR5 is not required for fl agellin-mediated exacerbation of DSS colitis. Infl amm. Bowel. Dis. 16, 401-409 (2010).
    • (2010) Infl amm. Bowel. Dis. , vol.16 , pp. 401-409
    • Ivison, S.M.1
  • 37
    • 77950250064 scopus 로고    scopus 로고
    • Metabolic syndrome and altered gut microbiota in mice lacking toll-like receptor 5
    • Vijay-Kumar, M. et al. Metabolic syndrome and altered gut microbiota in mice lacking toll-like receptor 5. Science 328, 228-231 (2010).
    • (2010) Science , vol.328 , pp. 228-231
    • Vijay-Kumar, M.1
  • 38
    • 0035953543 scopus 로고    scopus 로고
    • The innate immune response to bacterial fl agellin is mediated by Toll-like receptor 5
    • Hayashi, F. et al. The innate immune response to bacterial fl agellin is mediated by Toll-like receptor 5. Nature 410, 1099-1103 (2001).
    • (2001) Nature , vol.410 , pp. 1099-1103
    • Hayashi, F.1
  • 39
    • 33644915004 scopus 로고    scopus 로고
    • Serum interleukin-1 receptor antagonist is an early indicator of colitis onset in Galphai2-defi cient mice
    • Hultgren, O. H., Berglund, M., Bjursten, M. & Hultgren Hornquist, E. Serum interleukin-1 receptor antagonist is an early indicator of colitis onset in Galphai2-defi cient mice. World J. Gastroenterol. 12, 621-624 (2006).
    • (2006) World J. Gastroenterol. , vol.12 , pp. 621-624
    • Hultgren, O.H.1    Berglund, M.2    Bjursten, M.3    Hultgren Hornquist, E.4
  • 40
    • 0032768352 scopus 로고    scopus 로고
    • Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn's disease
    • Boudeau, J., Glasser, A. L., Masseret, E., Joly, B. & Darfeuille-Michaud, A. Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn's disease. Infect. Immun. 67, 4499-4509 (1999).
    • (1999) Infect. Immun. , vol.67 , pp. 4499-4509
    • Boudeau, J.1    Glasser, A.L.2    Masseret, E.3    Joly, B.4    Darfeuille-Michaud, A.5
  • 41
    • 0034873344 scopus 로고    scopus 로고
    • Adherent invasive Escherichia coli strains from patients with Crohn's disease survive and replicate within macrophages without inducing host cell death
    • Glasser, A. L. et al. Adherent invasive Escherichia coli strains from patients with Crohn's disease survive and replicate within macrophages without inducing host cell death. Infect. Immun. 69, 5529-5537 (2001).
    • (2001) Infect. Immun. , vol.69 , pp. 5529-5537
    • Glasser, A.L.1
  • 42
    • 0037408494 scopus 로고    scopus 로고
    • Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host
    • Barthel, M. et al. Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host. Infect. Immun. 71, 2839-2858 (2003).
    • (2003) Infect. Immun. , vol.71 , pp. 2839-2858
    • Barthel, M.1
  • 43
    • 28844444159 scopus 로고    scopus 로고
    • Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: Central role of epithelial-derived MMP
    • Castaneda, F. E. et al. Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: Central role of epithelial-derived MMP. Gastroenterology 129, 1991-2008 (2005).
    • (2005) Gastroenterology , vol.129 , pp. 1991-2008
    • Castaneda, F.E.1


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