-
1
-
-
77955472579
-
Evolving challenges in hepatic fibrosis
-
Friedman SL: Evolving challenges in hepatic fibrosis. Nat Rev Gastroenterol Hepatol, 2010; 7(8): 425-436
-
(2010)
Nat Rev Gastroenterol Hepatol
, vol.7
, Issue.8
, pp. 425-436
-
-
Friedman, S.L.1
-
2
-
-
63849191286
-
Modulation of TGF-beta signaling during progression of chronic liver diseases
-
Matsuzaki K: Modulation of TGF-beta signaling during progression of chronic liver diseases. Front Biosci, 2009; 14: 2923-34
-
(2009)
Front Biosci
, vol.14
, pp. 2923-2934
-
-
Matsuzaki, K.1
-
3
-
-
0038374866
-
Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis
-
Ueberham E, Low R, Ueberham U et al: Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis. Hepatology, 2003; 37(5): 1067-78
-
(2003)
Hepatology
, vol.37
, Issue.5
, pp. 1067-1078
-
-
Ueberham, E.1
Low, R.2
Ueberham, U.3
-
4
-
-
36248990744
-
Transforming growth factor beta mediates hepatocyte apoptosis through Smad3 generation of reactive oxygen species
-
Black D, Lyman S, Qian T et al: Transforming growth factor beta mediates hepatocyte apoptosis through Smad3 generation of reactive oxygen species. Biochimie, 2007; 89(12): 1464-73
-
(2007)
Biochimie
, vol.89
, Issue.12
, pp. 1464-1473
-
-
Black, D.1
Lyman, S.2
Qian, T.3
-
5
-
-
0035914339
-
Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3
-
Yuan W, Varga J: Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3. J Biol Chem, 2001; 276(42): 38502-10
-
(2001)
J Biol Chem
, vol.276
, Issue.42
, pp. 38502-38510
-
-
Yuan, W.1
Varga, J.2
-
6
-
-
3242758083
-
Suppression of matrix metalloproteinase-9 transcription by transforming growth factor-beta is mediated by a nuclear factor-kappaB site
-
Ogawa K, Chen F, Kuang C, Chen Y: Suppression of matrix metalloproteinase-9 transcription by transforming growth factor-beta is mediated by a nuclear factor-kappaB site. Biochem J, 2004; 381(Pt 2): 413-22
-
(2004)
Biochem J
, vol.381
, Issue.2
, pp. 413-422
-
-
Ogawa, K.1
Chen, F.2
Kuang, C.3
Chen, Y.4
-
7
-
-
28244454171
-
Nitric oxide induces TIMP-1 expression by activating the transforming growth factor beta-Smad signaling pathway
-
Akool el S, Doller A, Muller R et al: Nitric oxide induces TIMP-1 expression by activating the transforming growth factor beta-Smad signaling pathway. J Biol Chem, 2005; 280(47): 39403-16
-
(2005)
J Biol Chem
, vol.280
, Issue.47
, pp. 39403-39416
-
-
Akool el, S.1
Doller, A.2
Muller, R.3
-
8
-
-
77949261524
-
Alpha-lipoic acid inhibits hepatic PAI-1 expression and fibrosis by inhibiting the TGF-beta signaling pathwa
-
Min AK, Kim MK, Seo HY et al: Alpha-lipoic acid inhibits hepatic PAI-1 expression and fibrosis by inhibiting the TGF-beta signaling pathway. Biochem Biophys Res Commun, 2010; 393(3): 536-41
-
(2011)
Biochem Biophys Res Commu
, vol.39
, Issue.3
, pp. 536-541
-
-
Min, A.K.1
Kim, M.K.2
Seo, H.Y.3
-
9
-
-
48549084059
-
Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage
-
Dooley S, Hamzavi J, Ciuclan L et al: Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage. Gastroenterology, 2008; 135(2): 642-59
-
(2008)
Gastroenterology
, vol.135
, Issue.2
, pp. 642-659
-
-
Dooley, S.1
Hamzavi, J.2
Ciuclan, L.3
-
10
-
-
0034094837
-
Modulation of transforming growth factor beta response and signaling during transdifferentiation of rat hepatic stellate cells to myofibroblasts
-
Dooley S, Delvoux B, Lahme B et al: Modulation of transforming growth factor beta response and signaling during transdifferentiation of rat hepatic stellate cells to myofibroblasts. Hepatology, 2000; 31(5): 1094-106
-
(2000)
Hepatology
, vol.31
, Issue.5
, pp. 1094-1106
-
-
Dooley, S.1
Delvoux, B.2
Lahme, B.3
-
11
-
-
3242699717
-
UPA and uPAR in fibrinolysis, immunity and pathology
-
Mondino A, Blasi F: uPA and uPAR in fibrinolysis, immunity and pathology. Trends Immunol, 2004; 25(8): 450-55
-
(2004)
Trends Immunol
, vol.25
, Issue.8
, pp. 450-455
-
-
Mondino, A.1
Blasi, F.2
-
12
-
-
72949116366
-
Regulation of cell signalling by uPAR
-
Smith HW, Marshall CJ: Regulation of cell signalling by uPAR. Nat Rev Mol Cell Biol, 2010; 11(1): 23-36
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, Issue.1
, pp. 23-236
-
-
Smith, H.W.1
Marshall, C.J.2
-
13
-
-
0030976894
-
Extracellular cleavage of the vascular endothelial growth factor 189-amino acid form by urokinase is required for its mitogenic effect
-
Plouet J, Moro F, Bertagnolli S et al: Extracellular cleavage of the vascular endothelial growth factor 189-amino acid form by urokinase is required for its mitogenic effect. J Biol Chem, 1997; 272(20): 13390-96
-
(1997)
J Biol Chem
, vol.272
, Issue.20
, pp. 13390-13396
-
-
Plouet, J.1
Moro, F.2
Bertagnolli, S.3
-
14
-
-
23944450097
-
Activation of hepatocyte growth factor by urokinase-type plasminogen activator is ionic strength-dependent
-
Mars WM, Jo M, Gonias SL: Activation of hepatocyte growth factor by urokinase-type plasminogen activator is ionic strength-dependent. Biochem J, 2005; 390(Pt 1): 311-15
-
(2005)
Biochem J
, vol.390
, Issue.1
, pp. 311-315
-
-
Mars, W.M.1
Jo, M.2
Gonias, S.L.3
-
15
-
-
0028295979
-
Physiological consequences of loss of plasminogen activator gene function in mice
-
Carmeliet P, Schoonjans L, Kieckens L et al: Physiological consequences of loss of plasminogen activator gene function in mice. Nature, 1994; 368(6470): 419-24
-
(1994)
Nature
, vol.368
, Issue.6470
, pp. 419-424
-
-
Carmeliet, P.1
Schoonjans, L.2
Kieckens, L.3
-
16
-
-
33845630796
-
Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor
-
Shanmukhappa K, Sabla GE, Degen JL, Bezerra JA: Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor. BMC Gastroenterol, 2006; 6: 40
-
(2006)
BMC Gastroenterol
, vol.6
, pp. 40
-
-
Shanmukhappa, K.1
Sabla, G.E.2
Degen, J.L.3
Bezerra, J.A.4
-
18
-
-
77956202599
-
Protective action of hepatocyte growth factor on transforming growth factor beta-1-induced alpha-smooth muscle actin and extracellular matrix in cultured human peritoneal fibroblasts
-
Jiang D, Xu C, Li Z et al: Protective action of hepatocyte growth factor on transforming growth factor beta-1-induced alpha-smooth muscle actin and extracellular matrix in cultured human peritoneal fibroblasts. Med Sci Monit, 2010; 16(8): BR250-54
-
(2010)
Med Sci Monit
, vol.16
, Issue.8
-
-
Jiang, D.1
Xu, C.2
Li, Z.3
-
19
-
-
0035190758
-
Plasminogen deficiency leads to impaired lobular reorganization and matrix accumulation after chronic liver injury
-
Pohl JF, Melin-Aldana H, Sabla G et al: Plasminogen deficiency leads to impaired lobular reorganization and matrix accumulation after chronic liver injury. Am J Pathol, 2001; 159(6): 2179-86
-
(2001)
Am J Pathol
, vol.159
, Issue.6
, pp. 2179-2186
-
-
Pohl, J.F.1
Melin-Aldana, H.2
Sabla, G.3
-
20
-
-
0035153146
-
Accelerated skin wound healing in plasminogen activator inhibitor-1-deficient mice
-
Chan JC, Duszczyszyn DA, Castellino FJ, Ploplis VA: Accelerated skin wound healing in plasminogen activator inhibitor-1-deficient mice. Am J Pathol, 2001; 159(5): 1681-88
-
(2001)
Am J Pathol
, vol.159
, Issue.5
, pp. 1681-1688
-
-
Chan, J.C.1
Duszczyszyn, D.A.2
Castellino, F.J.3
Ploplis, V.A.4
-
21
-
-
0029998086
-
The plasminogen-activating system in hepatic stellate cells
-
Leyland H, Gentry J, Arthur MJ, Benyon RC: The plasminogen-activating system in hepatic stellate cells. Hepatology, 1996; 24(5): 1172-78
-
(1996)
Hepatology
, vol.24
, Issue.5
, pp. 1172-1178
-
-
Leyland, H.1
Gentry, J.2
Arthur, M.J.3
Benyon, R.C.4
-
22
-
-
33747602999
-
Urokinase plasminogen activator stimulates function of active forms of stromelysin and gelatinases (MMP-2 and MMP-9) in cirrhotic tissue
-
Gonzalez-Cuevas J, Bueno-Topete M, Armendariz-Borunda J: Urokinase plasminogen activator stimulates function of active forms of stromelysin and gelatinases (MMP-2 and MMP-9) in cirrhotic tissue. J Gastroenterol Hepatol, 2006; 21(10): 1544-54
-
(2006)
J Gastroenterol Hepatol
, vol.21
, Issue.10
, pp. 1544-1554
-
-
Gonzalez-Cuevas, J.1
Bueno-Topete, M.2
Armendariz-Borunda, J.3
-
23
-
-
31844432941
-
The induction of inflammation by adenovirus vectors used for gene therapy
-
Cotter MJ, Muruve DA: The induction of inflammation by adenovirus vectors used for gene therapy. Front Biosci, 2005; 10: 1098-105
-
(2005)
Front Biosci
, vol.10
, pp. 1098-1105
-
-
Cotter, M.J.1
Muruve, D.A.2
-
24
-
-
77952953570
-
Design of Ad5F35 vectors for coordinated dual gene expression in candidate human hematopoietic stem cells
-
Na M, Fan X: Design of Ad5F35 vectors for coordinated dual gene expression in candidate human hematopoietic stem cells. Exp Hematol, 2010; 38(6): 446-52
-
(2010)
Exp Hematol
, vol.38
, Issue.6
, pp. 446-452
-
-
Na, M.1
Fan, X.2
-
25
-
-
0030027934
-
Bicistronic vector for the creation of stable mammalian cell lines that predisposes all antibiotic-resistant cells to express recombinant protein
-
Rees S, Coote J, Stables J et al: Bicistronic vector for the creation of stable mammalian cell lines that predisposes all antibiotic-resistant cells to express recombinant protein. Biotechniques, 1996; 20(1): 102-4, 106, 108-10
-
(1996)
Biotechniques
, vol.20
, Issue.1
-
-
Rees, S.1
Coote, J.2
Stables, J.3
-
26
-
-
0037430141
-
Immune enhancement of nitroreductase-induced cytotoxicity: Studies using a bicistronic adenovirus vector
-
Green NK, McNeish IA, Doshi R et al: Immune enhancement of nitroreductase-induced cytotoxicity: studies using a bicistronic adenovirus vector. Int J Cancer, 2003; 104(1): 104-12
-
(2003)
Int J Cancer
, vol.104
, Issue.1
, pp. 104-112
-
-
Green, N.K.1
McNeish, I.A.2
Doshi, R.3
-
27
-
-
80054013435
-
The selected genetic polymorphisms of metalloproteinases MMP2, 7, 9 and MMP inhibitor TIMP2 in sarcoidosis
-
Piotrowski WJ, Górski P, Pietras T et al: The selected genetic polymorphisms of metalloproteinases MMP2, 7, 9 and MMP inhibitor TIMP2 in sarcoidosis. Med Sci Monit, 2011; 17(10): CR598-607
-
(2011)
Med Sci Monit
, vol.17
, Issue.10
-
-
Piotrowski, W.J.1
Górski, P.2
Pietras, T.3
-
28
-
-
0025332367
-
Sirius red histophotometry and spectrophotometry of sections in the assessment of the collagen content of liver tissue and its application in growing rat liver
-
James J, Bosch KS, Aronson DC, Houtkooper JM: Sirius red histophotometry and spectrophotometry of sections in the assessment of the collagen content of liver tissue and its application in growing rat liver. Liver, 1990; 10(1): 1-5
-
(1990)
Liver
, vol.10
, Issue.1
, pp. 1-5
-
-
James, J.1
Bosch, K.S.2
Aronson, D.C.3
Houtkooper, J.M.4
-
29
-
-
0036787684
-
Tissue inhibitor of metalloproteinases-1 attenuates spontaneous liver fibrosis resolution in the transgenic mouse
-
Yoshiji H, Kuriyama S, Yoshii J et al: Tissue inhibitor of metalloproteinases-1 attenuates spontaneous liver fibrosis resolution in the transgenic mouse. Hepatology, 2002; 36(4 Pt 1): 850-60
-
(2002)
Hepatology
, vol.36
, Issue.4 PART 1
, pp. 850-860
-
-
Yoshiji, H.1
Kuriyama, S.2
Yoshii, J.3
-
30
-
-
80054034723
-
Expression of angiotensinogen during hepatic fibrogenesis and its effect on hepatic stellate cells
-
Lu P, Liu H, Yin H, Yang L: Expression of angiotensinogen during hepatic fibrogenesis and its effect on hepatic stellate cells. Med Sci Monit, 2011; 17(9): BR248-56
-
(2011)
Med Sci Monit
, vol.17
, Issue.9
-
-
Lu, P.1
Liu, H.2
Yin, H.3
Yang, L.4
-
31
-
-
24044447311
-
Alpha-SMA expression in hepatic stellate cells and quantitative analysis of hepatic fibrosis in cirrhosis and in recurrent chronic hepatitis after liver transplantation
-
Carpino G, Morini S, Ginanni Corradini S et al: Alpha-SMA expression in hepatic stellate cells and quantitative analysis of hepatic fibrosis in cirrhosis and in recurrent chronic hepatitis after liver transplantation. Dig Liver Dis, 2005; 37(5): 349-56
-
(2005)
Dig Liver Dis
, vol.37
, Issue.5
, pp. 349-356
-
-
Carpino, G.1
Morini, S.2
Ginanni Corradini, S.3
-
32
-
-
0029026661
-
Cytokines and cellular crosstalk involved in the activation of fat-storing cells
-
Gressner AM: Cytokines and cellular crosstalk involved in the activation of fat-storing cells. J Hepatol, 1995; 22(Suppl.2): 28-36
-
(1995)
J Hepatol
, vol.22
, Issue.SUPPL. 2
, pp. 28-36
-
-
Gressner, A.M.1
-
33
-
-
0034614343
-
Enhanced interstitial collagenase (matrix metalloproteinase-13) production of Kupffer cell by gadolinium chloride prevents pig serum-induced rat liver fibrosis
-
Hironaka K, Sakaida I, Matsumura Y et al: Enhanced interstitial collagenase (matrix metalloproteinase-13) production of Kupffer cell by gadolinium chloride prevents pig serum-induced rat liver fibrosis. Biochem Biophys Res Commun, 2000; 267(1): 290-95
-
(2000)
Biochem Biophys Res Commun
, vol.267
, Issue.1
, pp. 290-295
-
-
Hironaka, K.1
Sakaida, I.2
Matsumura, Y.3
-
34
-
-
4544386785
-
Hepatocyte proliferation is the possible mechanism for the transient decrease in liver injury during steatosis stage of alcoholic liver disease
-
Apte UM, McRee R, Ramaiah SK: Hepatocyte proliferation is the possible mechanism for the transient decrease in liver injury during steatosis stage of alcoholic liver disease. Toxicol Pathol, 2004; 32(5): 567-76
-
(2004)
Toxicol Pathol
, vol.32
, Issue.5
, pp. 567-576
-
-
Apte, U.M.1
McRee, R.2
Ramaiah, S.K.3
-
35
-
-
2642585736
-
How can transforming growth factor beta be targeted usefully to combat liver fibrosis?
-
Shek FW, Benyon RC: How can transforming growth factor beta be targeted usefully to combat liver fibrosis? Eur J Gastroenterol Hepatol, 2004; 16(2): 123-26
-
(2004)
Eur J Gastroenterol Hepatol
, vol.16
, Issue.2
, pp. 123-126
-
-
Shek, F.W.1
Benyon, R.C.2
-
36
-
-
0035989936
-
Adenoviral delivery of an antisense RNA complementary to the 3' coding sequence of transforming growth factor-beta1 inhibits fibrogenic activities of hepatic stellate cells
-
Arias M, Lahme B, Van de Leur E et al: Adenoviral delivery of an antisense RNA complementary to the 3' coding sequence of transforming growth factor-beta1 inhibits fibrogenic activities of hepatic stellate cells. Cell Growth Differ, 2002; 13(6): 265-73
-
(2002)
Cell Growth Differ
, vol.13
, Issue.6
, pp. 265-273
-
-
Arias, M.1
Lahme, B.2
Van de Leur, E.3
-
37
-
-
33646488688
-
Combination gene therapy of HGF and truncated type II TGF-beta receptor for rat liver cirrhosis after partial hepatectomy
-
Ozawa S, Uchiyama K, Nakamori M et al: Combination gene therapy of HGF and truncated type II TGF-beta receptor for rat liver cirrhosis after partial hepatectomy. Surgery, 2006; 139(4): 563-73
-
(2006)
Surgery
, vol.139
, Issue.4
, pp. 563-573
-
-
Ozawa, S.1
Uchiyama, K.2
Nakamori, M.3
-
38
-
-
19944421105
-
Inhibition of TGF-beta signaling by an ALK5 inhibitor protects rats from dimethylnitrosamine-induced liver fibrosis
-
de Gouville AC, Boullay V, Krysa G et al: Inhibition of TGF-beta signaling by an ALK5 inhibitor protects rats from dimethylnitrosamine-induced liver fibrosis. Br J Pharmacol, 2005; 145(2): 166-77
-
(2005)
Br J Pharmacol
, vol.145
, Issue.2
, pp. 166-177
-
-
de Gouville, A.C.1
Boullay, V.2
Krysa, G.3
-
39
-
-
33751221303
-
Urokinasetype plasminogen activator gene therapy in liver cirrhosis is mediated by collagens gene expression down-regulation and up-regulation of MMPs, HGF and VEGF
-
Bueno M, Salgado S, Beas-Zarate C, Armendariz-Borunda J: Urokinasetype plasminogen activator gene therapy in liver cirrhosis is mediated by collagens gene expression down-regulation and up-regulation of MMPs, HGF and VEGF. J Gene Med, 2006; 8(11): 1291-99
-
(2006)
J Gene Med
, vol.8
, Issue.11
, pp. 1291-1299
-
-
Bueno, M.1
Salgado, S.2
Beas-Zarate, C.3
Armendariz-Borunda, J.4
-
40
-
-
0033166608
-
Induction of apoptosis in rat hepatic stellate cells by disruption of integrin-mediated cell adhesion
-
Iwamoto H, Sakai H, Tada S et al: Induction of apoptosis in rat hepatic stellate cells by disruption of integrin-mediated cell adhesion. J Lab Clin Med, 1999; 134(1): 83-89
-
(1999)
J Lab Clin Med
, vol.134
, Issue.1
, pp. 83-89
-
-
Iwamoto, H.1
Sakai, H.2
Tada, S.3
-
41
-
-
0032903634
-
Hepatocyte growth factor gene therapy of liver cirrhosis in rats
-
Ueki T, Kaneda Y, Tsutsui H et al: Hepatocyte growth factor gene therapy of liver cirrhosis in rats. Nat Med, 1999; 5(2): 226-30
-
(1999)
Nat Med
, vol.5
, Issue.2
, pp. 226-230
-
-
Ueki, T.1
Kaneda, Y.2
Tsutsui, H.3
-
42
-
-
19544368435
-
Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis
-
Halder SK, Beauchamp RD, Datta PK: Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis. Exp Cell Res, 2005; 307(1): 231-46
-
(2005)
Exp Cell Res
, vol.307
, Issue.1
, pp. 231-246
-
-
Halder, S.K.1
Beauchamp, R.D.2
Datta, P.K.3
-
43
-
-
22344450669
-
Cell type-specific intervention of transforming growth factor beta/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice
-
Inagaki Y, Kushida M, Higashi K et al: Cell type-specific intervention of transforming growth factor beta/Smad signaling suppresses collagen gene expression and hepatic fibrosis in mice. Gastroenterology, 2005; 129(1): 259-68
-
(2005)
Gastroenterology
, vol.129
, Issue.1
, pp. 259-268
-
-
Inagaki, Y.1
Kushida, M.2
Higashi, K.3
|