Immune enhancement of nitroreductase-induced cytotoxicity: Studies using a bicistronic adenovirus vector

International Journal of Cancer

Volumn 104, Issue 1, 2003, Pages 104-112

  Green, Nicola K ^a   McNeish, Iain A ^b   Doshi, Rajeev ^c   Searle, Peter F ^c   Kerr, David J ^a   Young, Lawrence S ^c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Adenovirus; Cancer; Gene therapy; GM CSF; Nitroreductase; VDEPT

Indexed keywords

ADENOVIRUS VECTOR; CYTOKINE; CYTOSINE DEAMINASE; GENE PRODUCT; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; NITROREDUCTASE; PRODRUG; THYMIDINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DIRECTED ENZYME PRODRUG THERAPY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER RECURRENCE; COLORECTAL CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; FEMALE; IMMUNITY; IMMUNOSTIMULATION; INTERNAL RIBOSOME ENTRY SITE; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUICIDE GENE THERAPY; TREATMENT PLANNING; VALIDATION PROCESS;

ADENOCARCINOMA; ADENOVIRUSES, HUMAN; ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; AZIRIDINES; BYSTANDER EFFECT; COLORECTAL NEOPLASMS; COMBINED MODALITY THERAPY; CYTOMEGALOVIRUS; DEFECTIVE VIRUSES; DRUG RESISTANCE, NEOPLASM; ESCHERICHIA COLI PROTEINS; FEMALE; GENE THERAPY; GENES; GENES, SYNTHETIC; GENETIC VECTORS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; IMMUNOTHERAPY; MESOTHELIOMA; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; NITROREDUCTASES; PRODRUGS; SPECIFIC PATHOGEN-FREE ORGANISMS; TUMOR CELLS, CULTURED;

EID: 0037430141     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10916     Document Type: Article

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