Accelerated skin wound healing in plasminogen activator inhibitor-1-deficient mice

American Journal of Pathology

Volumn 159, Issue 5, 2001, Pages 1681-1688

  Chan, Joyce C Y ^a   Duszczyszyn, Danielle A ^a   Castellino, Francis J ^a   Ploplis, Victoria A ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN; MATRIX PROTEIN; PLASMINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; FEMALE; FIBRINOLYSIS; KERATINOCYTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN BIOPSY; STRAIN DIFFERENCE; WOUND HEALING;

EID: 0035153146     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63015-5     Document Type: Article

References (27)

1. Differential expression of urokinase-type plasminogen activator and its type-1 inhibitor during healing of mouse skin wounds
2. Targeted inhibition of wound-induced PAI-1 expression alters migration and differentiation in human epidermal keratinocytes
3. Impaired wound healing in mice with a disrupted plasminogen gene
4. Loss of fibrinogen rescues mice from pleiotropic effects of plasminogen deficiency
5. Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: A gene targeting and gene transfer study in mice
6. Plasminogen activator inhibitor-1 deficiency protects against atherosclerosis progression in the mouse carotid artery
7. Remodeling of vessel wall after copper-induced injury is highly attenuated in mice with a total deficiency of plasminogen activator inhibitor-1
8. Plasminogen activator inhibitor-1 gene deficient mice. I: Generation by homologous recombination
9. Trichrome stainings and their preliminary technique
10. Ayoub-Shklar method for keratin and prekeratin
11. Histological and histochemical uses of periodic acid
12. Expression of vascular permeability factor (vascular endothelial growth factor) by epidermal keratinocytes during wound healing
13. Functional overlap between two classes of matrix-degrading proteases in wound healing
14. PAI-1 gene expression is growth state-regulated in cultured human epidermal keratinocytes during progression to confluence and post-wounding
15. Factors responsible for impaired fibrinolysis in obese subjects and NIDDM patients
16. Diabetes and wound healing
17. Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1
18. Epidermal plasminogen activator inhibitor (PAI) is immunologically identical to placental-type PAI-2
19. The plasminogen activator inhibitor-2 gene is not required for normal murine development or survival
20. A new family of 10 murine ovalbumin serpins includes two homologs of proteinase inhibitor 8 and two homologs of the granzyme B inhibitor (proteinase inhibitor 9)
21. Proteinase inhibitor 6 (PI-6) expression in human skin: Induction of PI-6 and a PI-6/proteinase complex during keratinocyte differentiation
22. Sequence, organization, chromosomal localization, and alternative splicing of the human serine protease inhibitor gene hurpin (PI13) which is up-regulated in psoriasis
23. Transient functional expression of alpha V beta 3 on vascular cells during wound repair
24. Urokinase and tissue-type plasminogen activators in keratinocytes during wound reepithelialization in vivo
25. Effects of plasminogen activator on epidermal cell migration
26. The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectin
27. Vitronectin is associated with increased wound fibrinolysis and decreased microvascular angiogenesis in mice