메뉴 건너뛰기




Volumn 16, Issue 2, 2004, Pages 123-126

How can transforming growth factor beta be targeted usefully to combat liver fibrosis?

Author keywords

Antifibrotic; Collagen; Connective tissue growth factor; Extracellular matrix; Fibrosis; Matrix metalloproteinase; Tissue inhibitor of matrix metalloproteinases; Transforming growth factor beta

Indexed keywords

CYTOKINE; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; PLASMINOGEN ACTIVATOR INHIBITOR; PROTEINASE INHIBITOR; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA; TGFB1 PROTEIN, HUMAN; TGFB1 PROTEIN, MOUSE; TGFB1 PROTEIN, RAT; THIOACETAMIDE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 2642585736     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-200402000-00001     Document Type: Article
Times cited : (135)

References (21)
  • 1
  • 2
    • 0029997830 scopus 로고    scopus 로고
    • Transdifferentiation of hepatic stellate cells (Ito cells) to myofibroblasts: A key event in hepatic fibrogenesis
    • Gressner AM. Transdifferentiation of hepatic stellate cells (Ito cells) to myofibroblasts: a key event in hepatic fibrogenesis. Kidney Int Suppl 1996; 54:339-45.
    • (1996) Kidney Int Suppl , vol.54 , pp. 339-345
    • Gressner, A.M.1
  • 3
    • 0032952079 scopus 로고    scopus 로고
    • Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver: Regulation by TNF-alpha and TGF-beta1
    • Knittel T, Mehde M, Kobold D, Saile B, Dinter C, Ramadori G. Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver: regulation by TNF-alpha and TGF-beta1. J Hepatol 1999; 30:48-60.
    • (1999) J Hepatol , vol.30 , pp. 48-60
    • Knittel, T.1    Mehde, M.2    Kobold, D.3    Saile, B.4    Dinter, C.5    Ramadori, G.6
  • 4
    • 0038374866 scopus 로고    scopus 로고
    • Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis
    • Ueberham E, Low R, Ueberham U, Schonig K, Bujard H. Conditional tetracycline-regulated expression of TGF-beta1 in liver of transgenic mice leads to reversible intermediary fibrosis. Hepatology 2003; 37: 1067-1078.
    • (2003) Hepatology , vol.37 , pp. 1067-1078
    • Ueberham, E.1    Low, R.2    Ueberham, U.3    Schonig, K.4    Bujard, H.5
  • 5
    • 0023751476 scopus 로고
    • Thioacetamide-induced cirrhosis-like liver lesions in rats - Usefulness and reliability of this animal model
    • Muller A, Machnik F, Zimmermann T, Schubert H. Thioacetamide-induced cirrhosis-like liver lesions in rats - usefulness and reliability of this animal model. Exp Pathol 1988; 34:229-236.
    • (1988) Exp Pathol , vol.34 , pp. 229-236
    • Muller, A.1    Machnik, F.2    Zimmermann, T.3    Schubert, H.4
  • 6
    • 0033515099 scopus 로고    scopus 로고
    • Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat
    • Qi Z, Atsuchi N, Ooshima A, Takeshita A, Ueno H. Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat. Proc Natl Acad Sci U S A 1999; 96:2345-2349.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 2345-2349
    • Qi, Z.1    Atsuchi, N.2    Ooshima, A.3    Takeshita, A.4    Ueno, H.5
  • 7
    • 0028953768 scopus 로고
    • Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions
    • Sanderson N, Factor V, Nagy P, Kopp J, Kondaiah P, Wakefield L, et al. Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions. Proc Natl Acad Sci U S A 1995; 92:2572-2576.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 2572-2576
    • Sanderson, N.1    Factor, V.2    Nagy, P.3    Kopp, J.4    Kondaiah, P.5    Wakefield, L.6
  • 8
    • 0033607304 scopus 로고    scopus 로고
    • In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: A potential new therapy for hepatic fibrosis
    • George J, Roulot D, Koteliansky VE, Bissell DM. In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: a potential new therapy for hepatic fibrosis. Proc Natl Acad Sci U S A 1999;96:12719-12724.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12719-12724
    • George, J.1    Roulot, D.2    Koteliansky, V.E.3    Bissell, D.M.4
  • 9
    • 0033109090 scopus 로고    scopus 로고
    • TGF-beta1 in liver fibrosis: An inducible transgenic mouse model to study liver fibrogenesis
    • Kanzler S, Lohse AW, Keil A, Henninger J, Dienes HP, Schirmacher P, et al. TGF-beta1 in liver fibrosis: an inducible transgenic mouse model to study liver fibrogenesis. Am J Physiol 1999; 276:G1059-G1068.
    • (1999) Am J Physiol , vol.276
    • Kanzler, S.1    Lohse, A.W.2    Keil, A.3    Henninger, J.4    Dienes, H.P.5    Schirmacher, P.6
  • 10
    • 0035899396 scopus 로고    scopus 로고
    • Hepatocellular expression of a dominant-negative mutant TGF-beta type II receptor accelerates chemically induced hepatocarcinogenesis
    • Kanzler S, Meyer E, Lohse AW, Schirmacher P, Henninger J, Galle PR, et al. Hepatocellular expression of a dominant-negative mutant TGF-beta type II receptor accelerates chemically induced hepatocarcinogenesis. Oncogene 2001; 20:5015-5024.
    • (2001) Oncogene , vol.20 , pp. 5015-5024
    • Kanzler, S.1    Meyer, E.2    Lohse, A.W.3    Schirmacher, P.4    Henninger, J.5    Galle, P.R.6
  • 11
    • 0035022130 scopus 로고    scopus 로고
    • Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-beta
    • Okuno M, Akita K, Moriwaki H; Kawada N, Ikeda K, Kaneda K, et al. Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-beta. Gastroenterology 2001; 120:1784-1800.
    • (2001) Gastroenterology , vol.120 , pp. 1784-1800
    • Okuno, M.1    Akita, K.2    Moriwaki, H.3    Kawada, N.4    Ikeda, K.5    Kaneda, K.6
  • 12
    • 0030987180 scopus 로고    scopus 로고
    • Biology of TGF-beta in knockout and transgenic mouse models
    • Bottinger EP, Letterio JJ, Roberts AB. Biology of TGF-beta in knockout and transgenic mouse models. Kidney Int 1997; 51:1355-1360.
    • (1997) Kidney Int , vol.51 , pp. 1355-1360
    • Bottinger, E.P.1    Letterio, J.J.2    Roberts, A.B.3
  • 13
    • 0028859738 scopus 로고
    • Onset and progression of pathological lesions in transforming growth factor-beta 1-deficient mice
    • Boivin GP, O'Toole BA, Orsmby IE, Diebold RJ, Eis MJ, Doetschman T, et al. Onset and progression of pathological lesions in transforming growth factor-beta 1-deficient mice. Am J Pathol 1995; 146:276-288.
    • (1995) Am J Pathol , vol.146 , pp. 276-288
    • Boivin, G.P.1    O'Toole, B.A.2    Orsmby, I.E.3    Diebold, R.J.4    Eis, M.J.5    Doetschman, T.6
  • 14
    • 0012979585 scopus 로고    scopus 로고
    • Connective tissue growth factor: An attractive therapeutic target in fibrotic renal disease
    • Crean JK, Lappin D, Godson C, Brady HR. Connective tissue growth factor: an attractive therapeutic target in fibrotic renal disease. Expert Opin Ther Targets 2001; 5:519-530.
    • (2001) Expert Opin Ther Targets , vol.5 , pp. 519-530
    • Crean, J.K.1    Lappin, D.2    Godson, C.3    Brady, H.R.4
  • 15
    • 0036098613 scopus 로고    scopus 로고
    • Expression of transforming growth factor-beta 1 by pancreatic stellate cells and its implications for matrix secretion and turnover in chronic pancreatitis
    • Shek FW, Benyon RC, Walker FM, McCrudden PR, Pender SL, Williams EJ, et al. Expression of transforming growth factor-beta 1 by pancreatic stellate cells and its implications for matrix secretion and turnover in chronic pancreatitis. Am J Pathol 2002; 160:1787-1798.
    • (2002) Am J Pathol , vol.160 , pp. 1787-1798
    • Shek, F.W.1    Benyon, R.C.2    Walker, F.M.3    McCrudden, P.R.4    Pender, S.L.5    Williams, E.J.6
  • 16
    • 20644465610 scopus 로고    scopus 로고
    • Progelatinase a is produced and activated by rat hepatic stellate cells and promotes their proliferation
    • Benyon RC, Novell CJ, Da Gaca M, Jones EH, Iredale JP, Arthur MJ. Progelatinase A is produced and activated by rat hepatic stellate cells and promotes their proliferation. Hepatology 1999; 30:977-986.
    • (1999) Hepatology , vol.30 , pp. 977-986
    • Benyon, R.C.1    Novell, C.J.2    Da Gaca, M.3    Jones, E.H.4    Iredale, J.P.5    Arthur, M.J.6
  • 17
    • 0032765483 scopus 로고    scopus 로고
    • MMP2 activation by collagen I and concanavalin A in cultured human hepatic stellate cells
    • Theret N, Lehti K, Musso O, Clement B. MMP2 activation by collagen I and concanavalin A in cultured human hepatic stellate cells. Hepatology 1999; 30:462-468.
    • (1999) Hepatology , vol.30 , pp. 462-468
    • Theret, N.1    Lehti, K.2    Musso, O.3    Clement, B.4
  • 18
    • 0036479206 scopus 로고    scopus 로고
    • Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2
    • Olaso E, Labrador JP, Wang L, Ikeda K, Eng FJ, Klein R, et al. Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2. J Biol Chem 2002; 277:3606-3613.
    • (2002) J Biol Chem , vol.277 , pp. 3606-3613
    • Olaso, E.1    Labrador, J.P.2    Wang, L.3    Ikeda, K.4    Eng, F.J.5    Klein, R.6
  • 19
    • 0037268098 scopus 로고    scopus 로고
    • Mutation in collagen-1 that confers resistance to the action of collagenase results in failure of recovery from CCI4-induced liver fibrosis, persistence of activated hepatic stellate cells, and diminished hepatocyte regeneration
    • Issa R, Zhou X, Trim N, Millward-Sadler H, Krane S, Benyon C, et al. Mutation in collagen-1 that confers resistance to the action of collagenase results in failure of recovery from CCI4-induced liver fibrosis, persistence of activated hepatic stellate cells, and diminished hepatocyte regeneration. FASEB J 2003; 17:47-49.
    • (2003) FASEB J , vol.17 , pp. 47-49
    • Issa, R.1    Zhou, X.2    Trim, N.3    Millward-Sadler, H.4    Krane, S.5    Benyon, C.6
  • 20
    • 0032557461 scopus 로고    scopus 로고
    • Identification of a transforming growth factor-betal/ bone morphogenetic protein 4 (TGF-beta1/BMP4) response element within the mouse tissue transglutaminase gene promoter
    • Ritter SJ, Davies PJ. Identification of a transforming growth factor-betal/ bone morphogenetic protein 4 (TGF-beta1/BMP4) response element within the mouse tissue transglutaminase gene promoter. J Biol Chem 1998; 273:12798-12806.
    • (1998) J Biol Chem , vol.273 , pp. 12798-12806
    • Ritter, S.J.1    Davies, P.J.2
  • 21
    • 0036901574 scopus 로고    scopus 로고
    • Transglutaminases: Nature's biological glues
    • Griffin M, Casadio R, Bergamini CM. Transglutaminases: nature's biological glues. Biochem J 2002; 368:377-396.
    • (2002) Biochem J , vol.368 , pp. 377-396
    • Griffin, M.1    Casadio, R.2    Bergamini, C.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.