Protective action of hepatocyte growth factor on transforming growth factor β-1-induced α-smooth muscle actin and extracellular matrix in cultured human peritoneal fibroblasts

Case Reports and Clinical Practice Review

Volumn 16, Issue 8, 2010, Pages

  Jiang, Dapeng ^a   Xu, Changqing ^a   Li, Zhaozhu ^a   Zhang, Yubo ^a   Han, Fuyou ^a   Jiang, Zhitao ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

smooth muscle actin; Adhesion; Extracellular matrix; Hepatocyte growth factor; Transforming growth factor

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; FIBRONECTIN; SCATTER FACTOR; SCLEROPROTEIN; TRANSFORMING GROWTH FACTOR BETA1; ACTIN; PROTECTIVE AGENT;

ADULT; ARTICLE; CLINICAL ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; PERITONEUM ADHESION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; SUPERNATANT; WESTERN BLOTTING; CONCENTRATION RESPONSE; DRUG EFFECT; EXTRACELLULAR MATRIX; FIBROBLAST; PERITONEUM; PROTEIN SYNTHESIS; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; METABOLISM; MIDDLE AGED;

ACTINS; ADULT; CELLS, CULTURED; COLLAGEN TYPE I; EXTRACELLULAR MATRIX; FIBROBLASTS; FIBRONECTINS; HEPATOCYTE GROWTH FACTOR; HUMANS; MIDDLE AGED; PERITONEUM; PROTECTIVE AGENTS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 77956202599     PISSN: 15076164     EISSN: 16433742     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Dijkstra FR, Nieuwenhuijzen M, Reijnen MM, van Goor H: Recent clinical developments in pathophysiology, epidemiology, diagnosis and treatment of intra-abdominal adhesions. Scand J Gastroenterol Suppl, 2000; 232: 52-59
2. Saed GM, Zhang W, Diamond MP: Molecular characterization of fibroblasts isolated from human peritoneum and adhesions. Fertil Steril, 2001; 75: 763-68
3. Thaler K, Mack JA, Zhao RH et al: Expression of connective tissue growth factor in intra-abdominal adhesions. Dis Colon Rectum, 2002; 45: 1510-19
4. Ghellai AM, Stucchi AF, Chegini N et al: Role of Transforming Growth Factor Beta-l in Peritonitis-Induced Adhesions. J Gastrointest Surg, 2000; 4: 316-23
5. Rout UK, Saed GM, Diamond MP: Transforming growth factor-beta1 modulates expression of adhesion and cytoskeletal proteins in human peritoneal fibroblasts. Fertil Steril, 2002; 78: 154-61
6. Klein MB, Yalamanchi N, Pham H et al: Flexor tendon healing in vitro: effects of TGF-beta on tendon cell collagen production. J Hand Surg Am, 2002; 27: 615-20
7. Michalik M, Pierzchalska M, Legutko A et al: Asthmatic bronchial fibroblasts demonstrate enhanced potential to differentiate into myofibroblasts in culture. Med Sci Monit, 2009; 15(7): BR194-201
8. Xu X, Rivkind A, Pappo O et al: Role of mast cells and myofibroblasts in human peritoneal adhesion formation. Ann Sur, 2002; 236: 593-601
9. Nedelec B, Ghahary A, Scott PG, Tredget EE: Control of wound contraction. Basic and clinical features. Hand Clin, 2000; 16: 289-302
10. Saed GM, Diamond MP: Differential expression of alpha smooth muscle cell actin in human fibroblasts isolated from intraperitoneal adhesions and normal peritoneal tissues. Fertil Steril, 2004; 82: 1188-92
11. Liu HJ, Wu CT, Duan HF et al: Adenoviral-mediated gene expression of hepatocyte growth factor prevents postoperative peritoneal adhesion in a rat model. Surgery, 2006; 140: 441-47
12. Naiki Y, Matsuo K, Matsuoka T, Maeda Y: Possible role of hepatocyte growth factor in regeneration of human peritoneal mesothelial cells. Int J Artif Organs, 2005; 28: 141-49
13. Dai C, Liu Y: Hepatocyte growth factor antagonizes the profibrotic action of TGF-beta1 in mesangial cells by stabilizing Smad transcriptional corepressor TGIF. J Am Soc Nephrol, 2004; 15: 1402-12
14. Saed GM, Collins KL, Diamond MP: Transforming growth factors beta1, beta2 and beta3 and their receptors are differentially expressed in human peritoneal fibroblasts in response to hypoxia. Am J Reprod Immunol, 2002; 48: 387-93
15. Jiang D, Jiang Z, Han F et al: HGF suppresses the production of collagen type III and alpha-SMA induced by TGF-beta1 in healing fibroblasts. Eur J Appl Physiol, 2008; 103: 489-93
16. Attard JA, MacLean AR: Adhesive small bowel obstruction: epidemiology, biology and prevention. Can J Surg, 2007; 50: 291-300
17. Gorvy DA, Herrick SE, Shah M, Ferguson MW: Experimental manipulation of transforming growth factor-beta isoforms significantly affects adhesion formation in a murine surgical model. Am J Pathol, 2005; 167: 1005-19
18. Yang J, Dai C, Liu Y: Hepatocyte growth factor suppresses renal interstitial myofibroblast activation and intercepts Smad signal transduction. Am J Pathol, 2003; 163: 621-32
19. Virtanen I, Vartio T, Badley RA, Lehto VP: Fibronectin in adhesion, spreading and cytoskeletal organization of cultured fibroblasts. Nature, 1982; 298: 660-63
20. Agarwal C, Britton ZT, Alaseirlis DA et al: Healing and normal fibroblasts exhibit differential proliferation, collagen production, alpha-SMA expression, and contraction. Ann Biomed Eng, 2006; 34: 653-59
21. Gong R, Rifai A, Tolbert EM et al: Hepatocyte growth factor modulates matrix metalloproteinases and plasminogen activator/plasmin proteolytic pathways in progressive renal interstitial fibrosis. J Am Soc Nephrol, 2003; 14: 3047-60