In inflammatory reactive astrocytes co-cultured with brain endothelial cells nicotine-evoked Ca2+ transients are attenuated due to interleukin-1β release and rearrangement of actin filaments

Neuroscience

Volumn 159, Issue 2, 2009, Pages 770-779

  Delbro, D ^a,b   Westerlund, A ^c   Bjorklund U ^c   Hansson, E ^c  

^a LINNAEUS UNIVERSITY   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

co cultured astrocytes; glial cells; LPS; neuroinflammation; nicotine; nicotinic receptors

Indexed keywords

BUNGAROTOXIN RECEPTOR; CALCITONIN; CALCIUM; F ACTIN; FURA 2; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; NICOTINE; NICOTINIC RECEPTOR ALPHA4BETA2; PHALLOIDIN; RYANODINE; SUBSTANCE P;

ACTIN FILAMENT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTROCYTE; BRAIN CELL; COCULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; INFLAMMATION; MALE; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; BRAIN; CALCITONIN GENE-RELATED PEPTIDE; CALCIUM; CELLS, CULTURED; COCULTURE TECHNIQUES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENDOTHELIAL CELLS; INTERLEUKIN-1BETA; LEPTIN; LIPOPOLYSACCHARIDES; MALE; MICROFILAMENTS; NICOTINE; NICOTINIC AGONISTS; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANCE P; TIME FACTORS;

EID: 60849089605     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.01.005     Document Type: Article

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