-
1
-
-
79952708723
-
Endoplasmic reticulum stress in liver disease
-
H. Malhi, and R.J. Kaufman Endoplasmic reticulum stress in liver disease J Hepatol 54 2010 795 809
-
(2010)
J Hepatol
, vol.54
, pp. 795-809
-
-
Malhi, H.1
Kaufman, R.J.2
-
2
-
-
56649094325
-
Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease
-
H. Malhi, and G.J. Gores Molecular mechanisms of lipotoxicity in nonalcoholic fatty liver disease Semin Liver Dis 28 2008 360 369
-
(2008)
Semin Liver Dis
, vol.28
, pp. 360-369
-
-
Malhi, H.1
Gores, G.J.2
-
3
-
-
79960740818
-
Activating transcription factor 6 plays protective and pathological roles in steatosis due to endoplasmic reticulum stress in zebrafish
-
A. Cinaroglu, C. Gao, D. Imrie, and K.C. Sadler Activating transcription factor 6 plays protective and pathological roles in steatosis due to endoplasmic reticulum stress in zebrafish Hepatology 54 2011 495 508
-
(2011)
Hepatology
, vol.54
, pp. 495-508
-
-
Cinaroglu, A.1
Gao, C.2
Imrie, D.3
Sadler, K.C.4
-
4
-
-
9144228073
-
Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II
-
K. Yamamoto, H. Yoshida, K. Kokame, R.J. Kaufman, and K. Mori Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II J Biochem (Tokyo) 136 2004 343 350
-
(2004)
J Biochem (Tokyo)
, vol.136
, pp. 343-350
-
-
Yamamoto, K.1
Yoshida, H.2
Kokame, K.3
Kaufman, R.J.4
Mori, K.5
-
5
-
-
57049111040
-
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators
-
D.T. Rutkowski, J. Wu, S.H. Back, M.U. Callaghan, S.P. Ferris, and J. Iqbal UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators Dev Cell 15 2008 829 840
-
(2008)
Dev Cell
, vol.15
, pp. 829-840
-
-
Rutkowski, D.T.1
Wu, J.2
Back, S.H.3
Callaghan, M.U.4
Ferris, S.P.5
Iqbal, J.6
-
6
-
-
84858987289
-
Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model
-
J.S. Lee, Z. Zheng, R. Mendez, S.W. Ha, Y. Xie, and K. Zhang Pharmacologic ER stress induces non-alcoholic steatohepatitis in an animal model Toxicol Lett 211 2012 29 38
-
(2012)
Toxicol Lett
, vol.211
, pp. 29-38
-
-
Lee, J.S.1
Zheng, Z.2
Mendez, R.3
Ha, S.W.4
Xie, Y.5
Zhang, K.6
-
7
-
-
81755184374
-
The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress
-
B.F. Teske, S.A. Wek, P. Bunpo, J.K. Cundiff, J.N. McClintick, and T.G. Anthony The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress Mol Biol Cell 22 2011 4390 4405
-
(2011)
Mol Biol Cell
, vol.22
, pp. 4390-4405
-
-
Teske, B.F.1
Wek, S.A.2
Bunpo, P.3
Cundiff, J.K.4
McClintick, J.N.5
Anthony, T.G.6
-
8
-
-
79953794116
-
The unfolded protein response transducer IRE1alpha prevents ER stress-induced hepatic steatosis
-
K. Zhang, S. Wang, J. Malhotra, J.R. Hassler, S.H. Back, and G. Wang The unfolded protein response transducer IRE1alpha prevents ER stress-induced hepatic steatosis EMBO J 30 2011 1357 1375
-
(2011)
EMBO J
, vol.30
, pp. 1357-1375
-
-
Zhang, K.1
Wang, S.2
Malhotra, J.3
Hassler, J.R.4
Back, S.H.5
Wang, G.6
-
9
-
-
77449096697
-
Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance
-
R. Ye, D.Y. Jung, J.Y. Jun, J. Li, S. Luo, and H.J. Ko Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance Diabetes 59 2010 6 16
-
(2010)
Diabetes
, vol.59
, pp. 6-16
-
-
Ye, R.1
Jung, D.Y.2
Jun, J.Y.3
Li, J.4
Luo, S.5
Ko, H.J.6
-
10
-
-
78650615554
-
Sarco(endo)plasmic reticulum Ca2+-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity
-
S.W. Park, Y. Zhou, J. Lee, and U. Ozcan Sarco(endo)plasmic reticulum Ca2+-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity Proc Natl Acad Sci U S A 107 2010 19320 19325
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 19320-19325
-
-
Park, S.W.1
Zhou, Y.2
Lee, J.3
Ozcan, U.4
-
11
-
-
79957605136
-
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
-
S. Fu, L. Yang, P. Li, O. Hofmann, L. Dicker, and W. Hide Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity Nature 473 2011 528 531
-
(2011)
Nature
, vol.473
, pp. 528-531
-
-
Fu, S.1
Yang, L.2
Li, P.3
Hofmann, O.4
Dicker, L.5
Hide, W.6
-
12
-
-
0037960128
-
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice
-
C. Ji, and N. Kaplowitz Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice Gastroenterology 124 2003 1488 1499
-
(2003)
Gastroenterology
, vol.124
, pp. 1488-1499
-
-
Ji, C.1
Kaplowitz, N.2
-
13
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
U. Ozcan, Q. Cao, E. Yilmaz, A.H. Lee, N.N. Iwakoshi, and E. Ozdelen Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes Science 306 2004 457 461
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
-
14
-
-
38649124615
-
Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease
-
P. Puri, F. Mirshahi, O. Cheung, R. Natarajan, J.W. Maher, and J.M. Kellum Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease Gastroenterology 134 2008 568 576
-
(2008)
Gastroenterology
, vol.134
, pp. 568-576
-
-
Puri, P.1
Mirshahi, F.2
Cheung, O.3
Natarajan, R.4
Maher, J.W.5
Kellum, J.M.6
-
15
-
-
77953482821
-
In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C
-
T. Asselah, I. Bieche, A. Mansouri, I. Laurendeau, D. Cazals-Hatem, and G. Feldmann In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C J Pathol 221 2010 264 274
-
(2010)
J Pathol
, vol.221
, pp. 264-274
-
-
Asselah, T.1
Bieche, I.2
Mansouri, A.3
Laurendeau, I.4
Cazals-Hatem, D.5
Feldmann, G.6
-
16
-
-
16244405250
-
Hepatitis C virus, ER stress, and oxidative stress
-
K.D. Tardif, G. Waris, and A. Siddiqui Hepatitis C virus, ER stress, and oxidative stress Trends Microbiol 13 2005 159 163
-
(2005)
Trends Microbiol
, vol.13
, pp. 159-163
-
-
Tardif, K.D.1
Waris, G.2
Siddiqui, A.3
-
17
-
-
79551483434
-
Endoplasmic reticulum stress is a mediator of posttransplant injury in severely steatotic liver allografts
-
C.D. Anderson, G. Upadhya, K.D. Conzen, J. Jia, E.M. Brunt, and V. Tiriveedhi Endoplasmic reticulum stress is a mediator of posttransplant injury in severely steatotic liver allografts Liver Transpl 17 2011 189 200
-
(2011)
Liver Transpl
, vol.17
, pp. 189-200
-
-
Anderson, C.D.1
Upadhya, G.2
Conzen, K.D.3
Jia, J.4
Brunt, E.M.5
Tiriveedhi, V.6
-
18
-
-
79959544189
-
Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice
-
C. Ji, N. Kaplowitz, M.Y. Lau, E. Kao, L.M. Petrovic, and A.S. Lee Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice Hepatology 54 2011 229 239
-
(2011)
Hepatology
, vol.54
, pp. 229-239
-
-
Ji, C.1
Kaplowitz, N.2
Lau, M.Y.3
Kao, E.4
Petrovic, L.M.5
Lee, A.S.6
-
19
-
-
66449137379
-
GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice
-
H.L. Kammoun, H. Chabanon, I. Hainault, S. Luquet, C. Magnan, and T. Koike GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice J Clin Invest 119 2009 1201 1215
-
(2009)
J Clin Invest
, vol.119
, pp. 1201-1215
-
-
Kammoun, H.L.1
Chabanon, H.2
Hainault, I.3
Luquet, S.4
Magnan, C.5
Koike, T.6
-
20
-
-
45849137877
-
Regulation of hepatic lipogenesis by the transcription factor XBP1
-
A.H. Lee, E.F. Scapa, D.E. Cohen, and L.H. Glimcher Regulation of hepatic lipogenesis by the transcription factor XBP1 Science 320 2008 1492 1496
-
(2008)
Science
, vol.320
, pp. 1492-1496
-
-
Lee, A.H.1
Scapa, E.F.2
Cohen, D.E.3
Glimcher, L.H.4
-
21
-
-
77956232915
-
Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress
-
K. Yamamoto, K. Takahara, S. Oyadomari, T. Okada, T. Sato, and A. Harada Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress Mol Biol Cell 21 2010 2975 2986
-
(2010)
Mol Biol Cell
, vol.21
, pp. 2975-2986
-
-
Yamamoto, K.1
Takahara, K.2
Oyadomari, S.3
Okada, T.4
Sato, T.5
Harada, A.6
-
22
-
-
44349163999
-
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice
-
S. Oyadomari, H.P. Harding, Y. Zhang, M. Oyadomari, and D. Ron Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice Cell Metab 7 2008 520 532
-
(2008)
Cell Metab
, vol.7
, pp. 520-532
-
-
Oyadomari, S.1
Harding, H.P.2
Zhang, Y.3
Oyadomari, M.4
Ron, D.5
-
23
-
-
77955411159
-
Tauroursodeoxycholic acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women
-
M. Kars, L. Yang, M.F. Gregor, B.S. Mohammed, T.A. Pietka, and B.N. Finck Tauroursodeoxycholic acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women Diabetes 59 2010 1899 1905
-
(2010)
Diabetes
, vol.59
, pp. 1899-1905
-
-
Kars, M.1
Yang, L.2
Gregor, M.F.3
Mohammed, B.S.4
Pietka, T.A.5
Finck, B.N.6
-
24
-
-
79952410092
-
Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and {beta}-cell dysfunction in humans
-
C. Xiao, A. Giacca, and G.F. Lewis Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and {beta}-cell dysfunction in humans Diabetes 60 2011 918 924
-
(2011)
Diabetes
, vol.60
, pp. 918-924
-
-
Xiao, C.1
Giacca, A.2
Lewis, G.F.3
-
25
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
U. Ozcan, E. Yilmaz, L. Ozcan, M. Furuhashi, E. Vaillancourt, and R.O. Smith Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes Science 313 2006 1137 1140
-
(2006)
Science
, vol.313
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
|