-
1
-
-
39349096526
-
Hematopoiesis: An evolving para-digm for stem cell biology
-
Orkin SH, Zon LI. Hematopoiesis: an evolving para-digm for stem cell biology. Cell. 2008;132:631-644.
-
(2008)
Cell
, vol.132
, pp. 631-644
-
-
Orkin, S.H.1
Zon, L.I.2
-
2
-
-
33750439078
-
The journey of developing hematopoietic stem cells
-
Mikkola HK, Orkin SH. The journey of developing hematopoietic stem cells. Development. 2006; 133:3733-3744.
-
(2006)
Development
, vol.133
, pp. 3733-3744
-
-
Mikkola, H.K.1
Orkin, S.H.2
-
3
-
-
33646671496
-
Transcriptional activa-tors, repressors, and epigenetic modifiers con-trolling hematopoietic stem cell development
-
Teitell MA, Mikkola HK. Transcriptional activa-tors, repressors, and epigenetic modifiers con-trolling hematopoietic stem cell development. Pediatr Res. 2006;59:33R-39R.
-
(2006)
Pediatr Res
, vol.59
-
-
Teitell, M.A.1
Mikkola, H.K.2
-
4
-
-
0033119549
-
Intersections between blood cell devel-opment and leukemia genes
-
discussion
-
Orkin SH, Porcher C, FujiwaraY, Visvader J, Wang LC. Intersections between blood cell devel-opment and leukemia genes. Cancer Res. 1999; 59[suppl]:1784S-1787S; discussion 1788S.
-
(1787)
Cancer Res. 1999
, vol.59
, Issue.SUPPL. 1784S
-
-
Orkin, S.H.1
Porcher, C.2
Fujiwara, Y.3
Visvader, J.4
Wang, L.C.5
-
5
-
-
0034045599
-
A transitional stage in the commitment of mesoderm to hematopoiesis requiring the transcription factor SCL/tal-1
-
Robertson SM, Kennedy M, Shannon JM, Keller G. A transitional stage in the commitment of mesoderm to hematopoiesis requiring the transcription factor SCL/tal-1. Development. 2000;127:2447-2459.
-
(2000)
Development
, vol.127
, pp. 2447-2459
-
-
Robertson, S.M.1
Kennedy, M.2
Shannon, J.M.3
Keller, G.4
-
6
-
-
0030750409
-
He- matopoietic-specific genes are not induced dur-ing in vitro differentiation of scl-null embryonic stem cells
-
ElefantyAG, Robb L, Birner R, Begley CG. He- matopoietic-specific genes are not induced dur-ing in vitro differentiation of scl-null embryonic stem cells. Blood. 1997;90:1435-1447.
-
(1997)
Blood
, vol.90
, pp. 1435-1447
-
-
Elefanty, A.G.1
Robb, L.2
Birner, R.3
Begley, C.G.4
-
7
-
-
0028858855
-
Absence of blood formation in mice lacking the T-cell leukae-mia oncoprotein tal-1/SCL
-
Shivdasani RA, Mayer EL, Orkin SH. Absence of blood formation in mice lacking the T-cell leukae-mia oncoprotein tal-1/SCL. Nature. 1995;373: 432-434.
-
(1995)
Nature
, vol.373
, pp. 432-434
-
-
Shivdasani, R.A.1
Mayer, E.L.2
Orkin, S.H.3
-
8
-
-
0029781248
-
Thescl gene product is required for the generation of all hematopoietic lineages in the adult mouse
-
Robb L, Elwood NJ, ElefantyAG, etal.Thescl gene product is required for the generation of all hematopoietic lineages in the adult mouse. EMBO J. 1996;15:4123-4129.
-
(1996)
EMBO J
, vol.15
, pp. 4123-4129
-
-
Robb, L.1
Elwood, N.J.2
Elefanty, A.G.3
-
9
-
-
0037438975
-
Expression of CD41 marks the initia-tion of definitive hematopoiesis in the mouse em-bryo
-
Mikkola HK, Fujiwara Y, Schlaeger TM, Traver D, Orkin SH. Expression of CD41 marks the initia-tion of definitive hematopoiesis in the mouse em-bryo. Blood. 2003;101:508-516.
-
(2003)
Blood
, vol.101
, pp. 508-516
-
-
Mikkola, H.K.1
Fujiwara, Y.2
Schlaeger, T.M.3
Traver, D.4
Orkin, S.H.5
-
10
-
-
18544364934
-
Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCLAaH)- dependent window during hematopoietic stem- cell development
-
SchlaegerTM, Mikkola HK, Gekas C, Helgadottir HB, Orkin SH. Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCLAaH)- dependent window during hematopoietic stem- cell development. Blood. 2005;105:3871-3874.
-
(2005)
Blood
, vol.105
, pp. 3871-3874
-
-
Schlaeger, T.M.1
Mikkola, H.K.2
Gekas, C.3
Helgadottir, H.B.4
Orkin, S.H.5
-
11
-
-
22544471496
-
Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia gene
-
Hall MA, Slater NJ, Begley CG, et al. Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia gene. Mol Cell Biol.2005;25:6355-6362.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 6355-6362
-
-
Hall, M.A.1
Slater, N.J.2
Begley, C.G.3
-
12
-
-
0037417892
-
The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythro- poiesis, and lineage choice in CFU-S12
-
Hall MA, Curtis DJ, Metcalf D, et al. The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythro- poiesis, and lineage choice in CFU-S12. Proc Natl Acad Sci USA. 2003;100:992-997.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 992-997
-
-
Hall, M.A.1
Curtis, D.J.2
Metcalf, D.3
-
13
-
-
33749364706
-
A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis
-
McCormack MP, Hall MA, Schoenwaelder SM, et al. A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis. Blood. 2006;108:2248-2256.
-
(2006)
Blood
, vol.108
, pp. 2248-2256
-
-
McCormack, M.P.1
Hall, M.A.2
Schoenwaelder, S.M.3
-
14
-
-
0142091497
-
Identification of aTAL1 target gene reveals a positive role for the LIM domain-binding protein Ldb1 in erythroid gene expression and differentia-ion
-
Xu Z, Huang S, Chang LS, Agulnick AD, Brandt SJ. Identification of aTAL1 target gene reveals a positive role for the LIM domain-binding protein Ldb1 in erythroid gene expression and differentia-ion. Mol Cell Biol. 2003;23:7585-7599.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7585-7599
-
-
Xu, Z.1
Huang, S.2
Chang, L.S.3
Agulnick, A.D.4
Brandt, S.J.5
-
15
-
-
0842304226
-
SCL as-embles a multifactorial complex that determines glycophorin A expression
-
Lahlil R, Lecuyer E, Herblot S, Hoang T. SCL as-embles a multifactorial complex that determines glycophorin A expression. Mol Cell Biol. 2004;24:1439-1452.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1439-1452
-
-
Lahlil, R.1
Lecuyer, E.2
Herblot, S.3
Hoang, T.4
-
16
-
-
0032722671
-
Specification of hematopoietic and vascular de-elopment by the bHLH transcription factor SCL without direct DNA binding
-
Porcher C, Liao EC, FujiwaraY, Zon LI, Orkin SH. Specification of hematopoietic and vascular de-elopment by the bHLH transcription factor SCL without direct DNA binding. Development. 1999;126:4603-4615.
-
(1999)
Development
, vol.126
, pp. 4603-4615
-
-
Porcher, C.1
Liao, E.C.2
Fujiwara, Y.3
Zon, L.I.4
Orkin, S.H.5
-
17
-
-
0032147039
-
-
Keller G, Wall C, Fong AZ, HawleyTS, Hawley RG. Overexpression of HOX11 leads to the im-mortalization of embryonic precursors with both primitive and definitive hematopoietic potential.Blood. 1998;92:877-887.
-
Keller G, Wall C, Fong AZ, HawleyTS, Hawley RG. Overexpression of HOX11 leads to the im-mortalization of embryonic precursors with both primitive and definitive hematopoietic potential.Blood. 1998;92:877-887.
-
-
-
-
18
-
-
0037208166
-
TRANSFAC: Transcriptional regulation, from pat-erns to profiles
-
Matys V, Fricke E, Geffers R, et al. (2003). TRANSFAC: transcriptional regulation, from pat-erns to profiles. Nucleic Acids Res. 2003;31:374-378.
-
(2003)
Nucleic Acids Res. 2003
, vol.31
, pp. 374-378
-
-
Matys, V.1
Fricke, E.2
Geffers, R.3
-
19
-
-
0021145261
-
Complete transformation by adenovirus 2 requires both E1A proteins
-
Montell C, Courtois G, Eng C, Berk A. Complete transformation by adenovirus 2 requires both E1A proteins. Cell. 1984;36:951-961.
-
(1984)
Cell
, vol.36
, pp. 951-961
-
-
Montell, C.1
Courtois, G.2
Eng, C.3
Berk, A.4
-
20
-
-
0031675951
-
Requirement of the MADS-box transcription factor MEF2C for vascular development
-
Lin Q, Lu J, Yanagisawa H, et al. Requirement of the MADS-box transcription factor MEF2C for vascular development. Development. 1998;125:4565-4574.
-
(1998)
Development
, vol.125
, pp. 4565-4574
-
-
Lin, Q.1
Lu, J.2
Yanagisawa, H.3
-
21
-
-
33847183440
-
MEF2C transcription factor controls chondrocyte hyper-trophy and bone development
-
Arnold MA, Kim Y, Czubryt MP, et al. MEF2C transcription factor controls chondrocyte hyper-trophy and bone development. Dev Cell. 2007;12:377-389.
-
(2007)
Dev Cell
, vol.12
, pp. 377-389
-
-
Arnold, M.A.1
Kim, Y.2
Czubryt, M.P.3
-
22
-
-
0037472895
-
Haemato-oietic stem cells retain long-term repopulating activity and multipotency in the absence of stem- cell leukaemia SCL/tal-1 gene
-
Mikkola HK, Klintman J, Yang H, et al. Haemato-oietic stem cells retain long-term repopulating activity and multipotency in the absence of stem- cell leukaemia SCL/tal-1 gene. Nature. 2003;421:547-551.
-
(2003)
Nature
, vol.421
, pp. 547-551
-
-
Mikkola, H.K.1
Klintman, J.2
Yang, H.3
-
23
-
-
39149100564
-
The emer-ence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation
-
Rhodes KE, Gekas C, Wang Y, et al. The emer-ence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation. Cell Stem Cell. 2008;2:252-263.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 252-263
-
-
Rhodes, K.E.1
Gekas, C.2
Wang, Y.3
-
25
-
-
0030911475
-
Control of mouse cardiac morphogenesis and myogen- esis by transcription factor MEF2C
-
Lin Q, Schwarz J, Bucana C, Olson EN. Control of mouse cardiac morphogenesis and myogen- esis by transcription factor MEF2C. Science.1997;276:1404-1407.
-
(1997)
Science
, vol.276
, pp. 1404-1407
-
-
Lin, Q.1
Schwarz, J.2
Bucana, C.3
Olson, E.N.4
-
26
-
-
0033566045
-
The transcription factor MEF2C-null mouse exhibits complex vas-ular malformations and reduced cardiac expression of angiopoietin 1 and VEGF
-
Bi W, Drake CJ, Schwarz JJ. The transcription factor MEF2C-null mouse exhibits complex vas-ular malformations and reduced cardiac expression of angiopoietin 1 and VEGF. Dev Biol. 1999;211:255-267.
-
(1999)
Dev Biol
, vol.211
, pp. 255-267
-
-
Bi, W.1
Drake, C.J.2
Schwarz, J.J.3
-
27
-
-
0034813102
-
Intraembryonic, but not yolk sac hemato- poietic precursors, isolated before circulation, provide long-term multilineage reconstitution
-
Cumano A, Ferraz JC, Klaine M, Di Santo JP, Godin I. Intraembryonic, but not yolk sac hemato- poietic precursors, isolated before circulation, provide long-term multilineage reconstitution. Im-unity. 2001;15:477-485.
-
(2001)
Im-unity
, vol.15
, pp. 477-485
-
-
Cumano, A.1
Ferraz, J.C.2
Klaine, M.3
Di Santo, J.P.4
Godin, I.5
-
28
-
-
0028842147
-
Emergence of multipotent hemopoietic cells in the yolk sac and paraaortic splanchnopleura in mouse embryos, beginning at 8.5 days postcoitus
-
S A
-
Godin I, Dieterlen-Lievre F, Cumano A. Emergence of multipotent hemopoietic cells in the yolk sac and paraaortic splanchnopleura in mouse embryos, beginning at 8.5 days postcoitus. Pro catl Acad Sci U S A. 1995;92:773-777.
-
(1995)
Pro catl Acad Sci U
, vol.92
, pp. 773-777
-
-
Godin, I.1
Dieterlen-Lievre, F.2
Cumano, A.3
-
29
-
-
0032520080
-
Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
-
Visvader JE, Fujiwara Y, Orkin SH. Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development. Genes Dev. 1998;12:473-479.
-
(1998)
Genes Dev
, vol.12
, pp. 473-479
-
-
Visvader, J.E.1
Fujiwara, Y.2
Orkin, S.H.3
-
30
-
-
0033566045
-
The transcription factor MEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expres-sion of angiopoietin 1 and VEGF
-
Bi W, Drake CJ, Schwarz JJ. The transcription factor MEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expres-sion of angiopoietin 1 and VEGF. Dev Biol. 1999;211:255-267.
-
(1999)
Dev Biol
, vol.211
, pp. 255-267
-
-
Bi, W.1
Drake, C.J.2
Schwarz, J.J.3
-
31
-
-
13444267759
-
Assessing the role of hemato- poietic plasticity for endothelial and hepatocyte development by non-invasive lineage tracing
-
Stadtfeld M, Graf T. Assessing the role of hemato- poietic plasticity for endothelial and hepatocyte development by non-invasive lineage tracing. De-velopment. 2005;132:203-213.
-
(2005)
De-velopment
, vol.132
, pp. 203-213
-
-
Stadtfeld, M.1
Graf, T.2
-
34
-
-
0036669273
-
-
marks the earliest lymphocyte progenitors in bone marrow. Immunity. 2002;17:117-130.
-
marks the earliest lymphocyte progenitors in bone marrow. Immunity. 2002;17:117-130.
-
-
-
-
35
-
-
43049102041
-
Gene-ontology driven transcriptional analysis of CD34+-cell initi-ated megakaryocyte cultures identifies new tran- scriptional regulators of megakaryopoiesis
-
Fuhrken PG, Chen C, Apostolidis PA, Wang M, Miller WM, Papoutsakis ET. Gene-ontology driven transcriptional analysis of CD34+-cell initi-ated megakaryocyte cultures identifies new tran- scriptional regulators of megakaryopoiesis. Physiol Genomics. 2008;22:159-169.
-
(2008)
Physiol Genomics
, vol.22
, pp. 159-169
-
-
Fuhrken, P.G.1
Chen, C.2
Apostolidis, P.A.3
Wang, M.4
Miller, W.M.5
Papoutsakis, E.T.6
-
36
-
-
0029590104
-
Co-operative activation of muscle gene expression by MEF2 and myogenic bHLH proteins
-
Molkentin JD, Black BL, Martin JF, Olson EN. Co-operative activation of muscle gene expression by MEF2 and myogenic bHLH proteins. Cell. 1995;83:1125-1136.
-
(1995)
Cell
, vol.83
, pp. 1125-1136
-
-
Molkentin, J.D.1
Black, B.L.2
Martin, J.F.3
Olson, E.N.4
-
37
-
-
0029841389
-
Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factors
-
Molkentin JD, Olson EN. Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factors. Proc Natl Acad Sci U S A. 1996;93:9366-9373.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 9366-9373
-
-
Molkentin, J.D.1
Olson, E.N.2
-
38
-
-
0141449169
-
mef2c is activated directly by myogenic basic helix-loop-helix pro-teins during skeletal muscle development in vivo
-
Dodou E, Xu SM, Black BL. mef2c is activated directly by myogenic basic helix-loop-helix pro-teins during skeletal muscle development in vivo. Mech Dev. 2003;120:1021-1032.
-
(2003)
Mech Dev
, vol.120
, pp. 1021-1032
-
-
Dodou, E.1
Xu, S.M.2
Black, B.L.3
-
39
-
-
0035203948
-
The Mef2c gene is a direct transcrip- tional target of myogenic bHLH and MEF2 pro-teins during skeletal muscle development
-
Wang DZ, Valdez MR, McAnally J, Richardson J, Olson EN. The Mef2c gene is a direct transcrip- tional target of myogenic bHLH and MEF2 pro-teins during skeletal muscle development. Development. 2001;128:4623-4633.
-
(2001)
Development
, vol.128
, pp. 4623-4633
-
-
Wang, D.Z.1
Valdez, M.R.2
McAnally, J.3
Richardson, J.4
Olson, E.N.5
-
40
-
-
0345647074
-
Characterization of myocyte enhancer factor 2 (MEF2) expression in B and T cells: MEF2C is a B cell-restricted transcription factor in lymphocytes
-
Swanson BJ, Jack HM, Lyons GE. Characterization of myocyte enhancer factor 2 (MEF2) expression in B and T cells: MEF2C is a B cell-restricted transcription factor in lymphocytes. Mol Immunol.1998;35:445-458.
-
(1998)
Mol Immunol
, vol.35
, pp. 445-458
-
-
Swanson, B.J.1
Jack, H.M.2
Lyons, G.E.3
-
41
-
-
20344400589
-
B cells, E2A, and aging
-
Riley RL, Blomberg BB, Frasca D. B cells, E2A, and aging. Immunol Rev. 2005;205:30-47.
-
(2005)
Immunol Rev
, vol.205
, pp. 30-47
-
-
Riley, R.L.1
Blomberg, B.B.2
Frasca, D.3
-
43
-
-
0031719473
-
Increased apoptosis of bone mar-row pre-B cells in old mice associated with their low number
-
Kirman I, Zhao K, Wang Y, Szabo P, Telford W, Weksler ME. Increased apoptosis of bone mar-row pre-B cells in old mice associated with their low number. Int Immunol. 1998;10:1385-1392.
-
(1998)
Int Immunol
, vol.10
, pp. 1385-1392
-
-
Kirman, I.1
Zhao, K.2
Wang, Y.3
Szabo, P.4
Telford, W.5
Weksler, M.E.6
-
44
-
-
0037291739
-
B cell precursors in senescent mice exhibit decreased recruitment into proliferative compartments and altered ex-pression of Bcl-2 family members
-
Sherwood EM, Xu W, Riley RL. B cell precursors in senescent mice exhibit decreased recruitment into proliferative compartments and altered ex-pression of Bcl-2 family members. Mech Ageing Dev. 2003;124:147-153.
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 147-153
-
-
Sherwood, E.M.1
Xu, W.2
Riley, R.L.3
-
45
-
-
44049105823
-
Tran-scription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimu-lation
-
Wilker PR, Kohyama M, Sandau MM, et al. Tran-scription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimu-lation. Nat Immunol. 2008;9:603-612.
-
(2008)
Nat Immunol
, vol.9
, pp. 603-612
-
-
Wilker, P.R.1
Kohyama, M.2
Sandau, M.M.3
-
46
-
-
47149093377
-
The MADS transcription factor Mef2c is a pivotal modulator of myeloid cell fate
-
Schuler A, Schwieger M, Engelmann A, et al. The MADS transcription factor Mef2c is a pivotal modulator of myeloid cell fate. Blood. 2008;111:4532-4541.
-
(2008)
Blood
, vol.111
, pp. 4532-4541
-
-
Schuler, A.1
Schwieger, M.2
Engelmann, A.3
-
47
-
-
27144554190
-
Cooperating cancer gene identification via onco- genic retrovirus-induced insertional mutagenesis
-
Du Y, Spence SE, Jenkins NA, Copeland NG. Cooperating cancer gene identification via onco- genic retrovirus-induced insertional mutagenesis. Blood. 2005;106:2498-2505.
-
(2005)
Blood
, vol.106
, pp. 2498-2505
-
-
Du, Y.1
Spence, S.E.2
Jenkins, N.A.3
Copeland, N.G.4
-
48
-
-
33746498580
-
Transfor-mation from committed progenitor to leukaemia stem cell initiated by MLL-AF9
-
Krivtsov AV, Twomey D, Feng Z, et al. Transfor-mation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature. 2006;442: 818-822.
-
(2006)
Nature
, vol.442
, pp. 818-822
-
-
Krivtsov, A.V.1
Twomey, D.2
Feng, Z.3
-
49
-
-
40749115609
-
MEF2C is activated by multiple mechanisms in a subset of T-acute lym- phoblastic leukemia cell lines
-
Nagel S, Meyer C, Quentmeier H, Kaufmann M, Drexler HG, Macleod RA. MEF2C is activated by multiple mechanisms in a subset of T-acute lym- phoblastic leukemia cell lines. Leukemia. 2008;22:600-607.
-
(2008)
Leukemia
, vol.22
, pp. 600-607
-
-
Nagel, S.1
Meyer, C.2
Quentmeier, H.3
Kaufmann, M.4
Drexler, H.G.5
Macleod, R.A.6
-
50
-
-
0036725051
-
New genes in-volved in cancer identified by retroviral tagging
-
Suzuki T, Shen H, Akagi K, et al. New genes in-volved in cancer identified by retroviral tagging. Nat Genet. 2002;32:166-174.
-
(2002)
Nat Genet
, vol.32
, pp. 166-174
-
-
Suzuki, T.1
Shen, H.2
Akagi, K.3
|