The structural basis of αβ T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function

Immunological Reviews

Volumn 250, Issue 1, 2012, Pages 102-119

  Wang, Jia huai ^a   Reinherz, Ellis L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Adaptive immunity; CD4; CD8; Mechanoreceptor; Structural immunology; T cell receptor

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEIN P56; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

AMINO ACID SEQUENCE; ANTIGEN ANTIBODY COMPLEX; ANTIGEN ANTIBODY REACTION; ANTIGEN RECOGNITION; ARTICLE; BETA SHEET; COMPLEX FORMATION; CYTOTOXIC T LYMPHOCYTE; HELPER CELL; HUMAN; MAJOR HISTOCOMPATIBILITY COMPLEX; MECHANOTRANSDUCTION; MOLECULAR DOCKING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE; RECEPTOR BINDING; STOICHIOMETRY;

ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS; ANTIGENS, CD3; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; HUMANS; MAJOR HISTOCOMPATIBILITY COMPLEX; MECHANOTRANSDUCTION, CELLULAR; MICE; MODELS, MOLECULAR; PEPTIDES; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA;

EID: 84867412117     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/j.1600-065X.2012.01161.x     Document Type: Article

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