The energetic basis underpinning T-cell receptor recognition of a super-bulged peptide bound to a major histocompatibility complex class I molecule

Journal of Biological Chemistry

Volumn 287, Issue 15, 2012, Pages 12267-12276

  Liu, Yu Chih ^a   Chen, Zhenjun ^b   Burrows, Scott R ^c   Purcell, Anthony W ^b   McCluskeys, James ^b   Rossjohn, Jamie ^a   Gras, Stephanie ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AFFINITY MEASUREMENT; ALANINE-SCANNING MUTAGENESIS; COMPLEMENTARITY-DETERMINING REGION 3; COMPLEMENTARITY-DETERMINING REGIONS; HUMAN LEUKOCYTE ANTIGEN; MAJOR HISTOCOMPATIBILITY COMPLEX CLASS; T-CELL RECEPTORS; TETRAMERS; VIRAL PEPTIDES;

AMINO ACIDS; CELL MEMBRANES; CRYSTAL STRUCTURE; OLIGOMERS;

PEPTIDES;

HLA B ANTIGEN; LEUCYLPROLYLGLUTAMYLPROLYLLEUCYLPROLYLGLUTAMINYLGLYCYLGLUTAMINYLLEUCYLTHREONYLALANYLTYROSINE PEPTIDE; PEPTIDE; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; ANTIGEN RECOGNITION; ARTICLE; BINDING SITE; COMPLEMENTARITY DETERMINING REGION; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENERGY TRANSFER; MUTATIONAL ANALYSIS; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOOTPRINTING; PROTEIN PROTEIN INTERACTION; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CRYSTALLOGRAPHY, X-RAY; HLA-B35 ANTIGEN; HUMANS; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PEPTIDES; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ANTIGEN, T-CELL; SURFACE PLASMON RESONANCE; SURFACE PROPERTIES; THERMODYNAMICS; VIRAL PROTEINS;

EID: 84859510074     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.344689     Document Type: Article

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