Potentiation of radiation sensitivity in breast tumor cells by the vitamin D3 analogue, EB 1089, through promotion of autophagy and interference with proliferative recovery

Molecular Cancer Therapeutics

Volumn 5, Issue 11, 2006, Pages 2786-2797

  DeMasters, Gerald ^a   Di, Xu ^a   Newsham, Irene ^b   Shiu, Robert ^c   Gewirtz, David A ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; COLECALCIFEROL DERIVATIVE; GLUTATHIONE; MYC PROTEIN; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SEOCALCITOL;

APOPTOSIS; ARTICLE; AUTOPHAGY; BREAST TUMOR; CELL AGING; CELL KILLING; CELL PROLIFERATION; CELL PROTECTION; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; HUMAN; HUMAN CELL; MITOSIS; PRIORITY JOURNAL; RADIOSENSITIVITY; SIGNAL TRANSDUCTION; TUMOR CELL; WILD TYPE;

ANTINEOPLASTIC AGENTS; AUTOPHAGY; BREAST NEOPLASMS; CALCITRIOL; CASPASE 3; CELL AGING; CELL PROLIFERATION; DNA DAMAGE; DNA REPAIR; FEMALE; FREE RADICALS; HUMANS; RADIATION TOLERANCE; REACTIVE OXYGEN SPECIES; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33845192397     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-06-0316     Document Type: Article

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