Zerumbone suppresses IKKα, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells

Journal of Biomedical Science

Volumn 19, Issue 1, 2012, Pages

  Weng, Hsing Yu ^a,b   Hsu, Ming Jen ^c   Wang, Ching Chung ^a   Chen, Bing Chang ^c   Hong, Chuang Ye ^d   Chen, Mei Chieh ^c   Chiu, Wen Ta ^a   Lin, Chien Huang ^c  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Akt; FOXO1; Glioblastoma multiforme; IKK; Zerumbone

Indexed keywords

CASPASE 3; I KAPPA B KINASE ALPHA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; ZERUMBONE; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; I KAPPA B KINASE; ONCOPROTEIN; SESQUITERPENE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL DESTRUCTION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVATION; FLOW CYTOMETRY; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GINGER; METABOLISM; PHOSPHORYLATION; TUMOR CELL LINE;

ZINGIBER OFFICINALE; ZINGIBER ZERUMBET;

APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GINGER; GLIOBLASTOMA; HUMANS; I-KAPPA B KINASE; ONCOGENE PROTEIN V-AKT; PHOSPHORYLATION; SESQUITERPENES; SIGNAL TRANSDUCTION;

EID: 84867002680     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1186/1423-0127-19-86     Document Type: Article

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