Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway Protects against Interleukin-3 Starvation but Not DNA Damage-induced Apoptosis

Journal of Biological Chemistry

Volumn 276, Issue 14, 2001, Pages 10935-10942

  Mathieu, Anne Laure ^a   Gonin, Sandrine ^a   Leverrier, Yann ^a   Blanquier, Bariza ^a   Thomas, Joëlle ^a   Dantin, Carole ^a   Martin, Guy ^a   Baverel, Gabriel ^a   Marvel, Jacqueline ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; DNA; ENZYME INHIBITION; MUTAGENESIS; PROTEINS;

ANTI-APOPTOTIC PATHWAYS; PHOSPHORYLATION;

BIOCHEMISTRY;

DNA; INTERLEUKIN 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL X; PROTEIN KINASE B; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVATION; GAMMA IRRADIATION; GLYCOLYSIS; MOUSE; MUTAGENESIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RETROVIRUS; ANIMAL; CELL DIVISION; CELL LINE; GENETICS; HUMAN; METABOLISM; MUTATION; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALIA; UNIDENTIFIED RETROVIRUS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; CELL DIVISION; CELL LINE; CELL SURVIVAL; DNA DAMAGE; ENZYME ACTIVATION; HUMANS; INTERLEUKIN-3; MUTATION; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 0035815701     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M007147200     Document Type: Article

References (51)

1. Rodriguez-Tarduchy, G., Collins, M., and Lopez-Rivas, A. (1990) EMBO J. 9, 2997-3002
2. Miyajima, A., Ito, Y., and Kinoshita, T. (1999) Int. J. Hematol. 69, 137-146
3. Gotoh, N., Tojo, A., and Shibuya, M. (1996) EMBO J. 15, 6197-6204
4. Ikushima, S., Inukai, T., Inaba, T., Nimer, S. D., Cleveland, J. L., and Look, A. T. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 2609-2614
5. Datta, S. R., Brunet, A., and Greenberg, M. E. (1999) Genes Dev. 13, 2905-2927
6. Datta, S. R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y., and Greenberg, M. E. (1997) Cell 91, 231-241
7. Zha, J., Harada, H., Yang, E., Jockel, J., and Korsmeyer, S. J. (1996) Cell 87, 619-628
8. Cardone, M. H., Roy, N., Stennicke, H. R., Salvesen, G. S., Franke, T. F., Stanbridge, E., Frisch, S., and Reed, J. C. (1998) Science 282, 1318-1321
9. Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J., and Greenberg, M. E. (1999) Cell 96, 857-868
10. Kops, G. J., de Ruiter, N. D., De Vries-Smits, A. M., Powell, D. R., Bos, J. L., and Burgering, B. M. (1999) Nature 398, 630-634
11. Frasca, D., Pioli, C., Guidi, F., Pucci, S., Arbitrio, M., Leter, G., and Doria, G. (1996) Int. Immunol. 8, 1651-1657
12. Mor, F., and Cohen, I. R. (1996) J. Immunol. 156, 515-522
13. Collins, M. K., Marvel, J., Malde, P., and Lopez-Rivas, A. (1992) J. Exp. Med. 176, 1043-1051
14. Canman, C. E., Gilmer, T. M., Coutts, S. B., and Kastan, M. B. (1995) Genes Dev. 9, 600-611
15. Silva, A., Wyllie, A., and Collins, M. K. (1997) Blood 89, 2717-2722
16. Amundson, S. A., Myers, T. G., and Fornace, A. J., Jr. (1998) Oncogene 17, 3287-3299
17. Lakin, N. D., and Jackson, S. P. (1999) Oncogene 18, 7644-7655
18. Sionov, R. V., and Haupt, Y. (1999) Oncogene 18, 6145-6157
19. Miyashita, T., Krajewski, S., Krajewska, M., Wang, H. G., Lin, H. K., Liebermann, D. A., Hoffman, B., and Reed, J. C. (1994) Oncogene 9, 1799-1805
20. Owen-Schaub, L. B., Zhang, W., Cusack, J. C., Angelo, L. S., Santee, S. M., Fujiwara, T., Roth, J. A., Deisseroth, A. B., Zhang, W. W., Kruzel, E., and Radinsky, R. (1995) Mol. Cell. Biol. 15, 3032-3040
21. Attardi, L. D., Reczek, E. E., Cosmas, C., Demicco, E. G., McCurrach, M. E., Lowe, S. W., and Jacks, T. (2000) Genes Dev. 14, 704-718
22. Brady, H. J., Salomons, G. S., Bobeldijk, R. C., and Berns, A. J. (1996) EMBO J. 15, 1221-1230
23. Soengas, M. S., Alarcon, R. M., Yoshida, H., Giaccia, A. J., Hakem, R., Mak, T. W., and Lowe, S. W. (1999) Science 284, 156-159
24. Quelle, F. W., Wang, J., Feng, J., Wang, D., Cleveland, J. L., Ihle, J. N., and Zambetti, G. P. (1998) Genes Dev. 12, 1099-1107
25. Sabbatini, P., and McCormick, F. (1999) J. Biol. Chem. 274, 24263-24269
26. Gottlieb, E., and Oren, M. (1998) EMBO J. 17, 3587-3596
27. Thomas, J., Leverrier, Y., and Marvel, J. (1998) Oncogene 16, 1399-1408
28. Garland, J. M. (1984) Lymphokines 9, 153-200
29. Marvel, J., Perkins, G., Lopez Rivas, A., and Collins, M. (1994) Oncogene 9, 1117-1122
30. Stocking, C., Bergholz, U., Friel, J., Klingler, K., Wagener, T., Starke, C., Kitamura, T., Miyajima, A., and Ostertag, W. (1993) Growth Factors 8, 197-209
31. Krebs, H. A., and Henseleit, K. (1932) Physiol. Chem. 210, 33
32. Baverel, G., and Lund, P. (1979) Biochem. J. 184, 599-606
33. Baverel, G., Bonnard, M., D'Armagnac de Castanet, E., and Pellet, M. (1978) Kidney Int 14, 567-575
34. Minn, A. J., Rudin, C. M., Boise, L. H., and Thompson, C. B. (1995) Blood 86, 1903-1910
35. Hasthorpe, S., Carver, J. A., Rees, D., and Campbell, I. D. (1987) J. Cell. Physiol. 133, 351-357
36. Garland, J. M., and Halestrap, A. (1997) J. Biol. Chem. 272, 4680-4688
37. Deprez, J., Vertommen, D., Alessi, D. R., Hue, L., and Rider, M. H. (1997) J. Biol. Chem. 272, 17269-17275
38. Cross, D. A., Alessi, D. R., Cohen, P., Andjelkovich, M., and Hemmings, B. A. (1995) Nature 378, 785-789
39. Summers, S. A., Garza, L. A., Zhou, H., and Birnbaum, M. J. (1998) Mol. Cell. Biol. 18, 5457-5464
40. Wang, Q., Somwar, R., Bilan, P. J., Liu, Z., Jin, J., Woodgett, J. R., and Klip, A. (1999) Mol. Cell. Biol. 19, 4008-4018
41. Hill, M. M., Clark, S. F., Tucker, D. F., Birnbaum, M. J., James, D. E., and Macaulay, S. L. (1999) Mol. Cell. Biol. 19, 7771-7781
42. Franke, T. F., Kaplan, D. R., Cantley, L. C., and Toker, A. (1997) Science 275, 665-668
43. Leverrier, Y., Thomas, J., Mathieu, A. L., Low, W., Blanquier, B., and Marvel, J. (1999) Cell Death Differ. 6, 290-296
44. Guo, S., Rena, G., Cichy, S., He, X., Cohen, P., and Unterman, T. (1999) J. Biol. Chem. 274, 17184-17192
45. Leverrier, Y., Thomas, J., Perkins, G. R., Mangeney, M., Collins, M. K., and Marvel, J. (1997) Oncogene 14, 425-430
46. Socolovsky, M., Fallon, A. E., Wang, S., Brugnara, C., and Lodish, H. F. (1999) Cell 98, 181-191
47. Dumon, S., Santos, S. C., Debierre-Grockiego, F., Gouilleux-Gruart, V., Cocault, L., Boucheron, C., Mollat, P., Gisselbrecht, S., and Gouilleux, F. (1999) Oncogene 18, 4191-4199
48. Yang, F. C., Kapur, R., King, A. J., Tao, W., Kim, C., Borneo, J., Breese, R., Marshall, M., Dinauer, M. C., and Williams, D. A. (2000) Immunity 12, 557-568
49. Shim, H., Chun, Y. S., Lewis, B. C., and Dang, C. V. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 1511-1516
50. Rathmell, J. C., Vander Heiden, M. G., Harris, M. H., Frauwirth, K. A., and Thompson, C. B. (2000) Mol Cell 6, 683-692
51. Dang, C. V., and Semenza, G. L. (1999) Trends Biochem. Sci. 24, 68-72