Replication fork stalling and checkpoint activation by a PKD1 locus mirror repeat polypurine-polypyrimidine (Pu-Py) tract

Journal of Biological Chemistry

Volumn 287, Issue 40, 2012, Pages 33412-33423

  Liu, Guoqi ^a   Myers, Sheré ^a   Chen, Xiaomi ^a   Bissler, John J ^b   Sinden, Richard R ^c,d   Leffak, Michael ^a  

^a WRIGHT STATE UNIVERSITY   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c Florida Institute of Technology ^*  (United States)

^d SOUTH DAKOTA SCHOOL OF MINES AND TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT ACTIVATION; DNA DAMAGE RESPONSE; DNA REPLICATION FORKS; DNA SECONDARY STRUCTURES; G-QUADRUPLEXES; GENOMIC INSTABILITY; HOTSPOTS; HUMAN DISEASE; IN-VITRO; POLYCYSTIC KIDNEY DISEASE; PROTEIN BINDING; REPLICATION FORK; REPLICATION PROTEIN A;

BIOCHEMISTRY; DNA; GENES; PHOSPHORYLATION;

MIRRORS;

ATR PROTEIN; CHECKPOINT KINASE 1; PROTEIN RAD9; REPLICATION FACTOR A;

AMINO ACID SEQUENCE; ARTICLE; CELL CYCLE CHECKPOINT; CONTROLLED STUDY; DNA DAMAGE; DNA REPLICATION; DNA REPLICATION FORK STALLING; DNA STRUCTURE; GENOMIC INSTABILITY; HELA CELL; IN VITRO STUDY; ONCOGENE C MYC; POLYCYSTIC KIDNEY DISEASE 1 GENE; POLYPURINE POLYPYRIMIDINE MIRROR REPEAT TRACT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

CHROMATIN IMMUNOPRECIPITATION; CYTOSOL; DNA; DNA DAMAGE; DNA PRIMERS; DNA REPLICATION; GENOMIC INSTABILITY; HELA CELLS; HUMANS; INTRONS; NUCLEIC ACID CONFORMATION; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-MYC; PURINES; PYRIMIDINES; TRPP CATION CHANNELS;

EID: 84866949684     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.402503     Document Type: Article

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