The i-motif in the bcl-2 P1 promoter forms an unexpectedly stable structure with a unique 8:5:7 loop folding pattern

Journal of the American Chemical Society

Volumn 131, Issue 48, 2009, Pages 17667-17676

  Kendrick, Samantha ^a   Akiyama, Yoshitsugu ^d   Hecht, Sidney M ^d   Hurley, Laurence H ^a,b,c,e  

^a UNIVERSITY OF ARIZONA   (United States)

^b BIO5 Institute   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d ARIZONA STATE UNIVERSITY   (United States)

^e University of Arizona   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPPING STRUCTURE; DNA CONFORMATIONS; DNA SECONDARY STRUCTURES; FOLDING PATTERNS; FOOTPRINTING; G-QUADRUPLEX STRUCTURE; G-QUADRUPLEXES; I-MOTIF; INTRAMOLECULAR I-MOTIF; LATERAL LOOPS; LOOP CONFORMATION; LOOP REGIONS; POLYPYRIMIDINE; PROMOTER ACTIVITIES; PROMOTER REGION; REGULATORY PROTEIN; SMALL MOLECULES; STABLE STRUCTURES; THERMAL STABILITY; TRANSCRIPTIONAL REGULATION;

BROMINE; CONFORMATIONS; GENES; LAWS AND LEGISLATION; NUCLEIC ACIDS; POSITIVE IONS; PROTEINS; TRANSCRIPTION;

DNA;

BROMINE; COMPLEMENTARY DNA; CYTOSINE; GUANINE; PROTEIN BCL 2; PYRIMIDINE; THYMINE;

ARTICLE; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; DNA CONFORMATION; DNA FOOTPRINTING; DNA STRUCTURE; GC RICH SEQUENCE; HUMAN; NUCLEOTIDE SEQUENCE; PH; PROMOTER REGION; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; THERMOSTABILITY; TRANSCRIPTION REGULATION;

BASE PAIRING; BASE SEQUENCE; BROMINE; CIRCULAR DICHROISM; DEOXYURIDINE; DNA; DNA MUTATIONAL ANALYSIS; FLUORESCENT DYES; GC RICH SEQUENCE; HUMANS; HYDROGEN-ION CONCENTRATION; MOLECULAR SEQUENCE DATA; MUTATION; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-BCL-2; SEQUENCE DELETION; TEMPERATURE; THYMINE;

EID: 72249093969     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9076292     Document Type: Article

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