Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2

Nature

Volumn 449, Issue 7160, 2007, Pages 366-369

  Dentin, Renaud ^a   Liu, Yi ^a   Koo, Seung Hoi ^b   Hedrick, Susan ^a   Vargas, Thomas ^a   Heredia, Jose ^a   Yates III, John ^c   Montminy, Marc ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b Sungkyunkwan University   (South Korea)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; LIGASE; PROTEASOME; PROTEIN; PROTEIN KINASE B BETA; PROTEIN SERINE THREONINE KINASE; PROTEIN TORC2; SERINE THREONINE PROTEIN KINASE SIK2; UBIQUITIN; UBIQUITIN PROTEIN LIGASE COP1; UNCLASSIFIED DRUG;

DIABETES; FASTING; GENE EXPRESSION; GLUCOSE; HOMEOSTASIS; INHIBITION; PROTEOMICS; RODENT; TRANSLOCATION;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DIABETES MELLITUS; DOWN REGULATION; EMBRYO; FEEDING; GENE EXPRESSION REGULATION; GLUCONEOGENESIS; GLUCOSE HOMEOSTASIS; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; UBIQUITINATION;

MUS;

EID: 34548831102     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature06128     Document Type: Article

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