Transcriptional control of cell cycle-dependent kinase 4 by Smad proteins-implications for Alzheimer's disease

Neurobiology of Aging

Volumn 33, Issue 12, 2012, Pages 2827-2840

  Ueberham, Uwe ^a   Hilbrich, Isabel ^a   Ueberham, Elke ^a   Rohn, Susanne ^a   Glöckner, Pia ^a   Dietrich, Katharina ^a   Brückner, Martina K ^a   Arendt, Thomas ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Alzheimer's disease; Cdk4; Cell cycle; Neurodegeneration; Promoter; Smad4

Indexed keywords

CYCLIN DEPENDENT KINASE 4; LUCIFERASE; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT2; UNCLASSIFIED DRUG;

AGED; ALZHEIMER DISEASE; ARTICLE; CELL CYCLE DEPENDENT KINASE 4 GENE; CELL CYCLE REGULATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ASSAY; GEL MOBILITY SHIFT ASSAY; GENE; GENE REPRESSION; HUMAN; HUMAN TISSUE; MOLECULAR INTERACTION; MOLECULAR PROBE; MOUSE; NERVE FIBER GROWTH; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SEQUENCE ANALYSIS; SMAD2 GENE; SMAD3 GENE; SMAD4 GENE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ANALYSIS OF VARIANCE; ANIMALS; BRAIN; BUCLADESINE; CELL DEATH; CELL DIFFERENTIATION; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; CYCLIN-DEPENDENT KINASE 4; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; GENE EXPRESSION REGULATION; HUMANS; LUCIFERASES; MALE; MICE; NEURITES; NEUROBLASTOMA; NEURONS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN SUBUNITS; RNA, SMALL INTERFERING; SMAD PROTEINS; TRANSFECTION;

EID: 84866754507     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2012.01.013     Document Type: Article

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