메뉴 건너뛰기




Volumn 7, Issue 9, 2012, Pages

A Polymeric Protein Induces Specific Cytotoxicity in a TLR4 Dependent Manner in the Absence of Adjuvants

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; HERMES ANTIGEN; INTERLEUKIN 7 RECEPTOR ALPHA; LUMAZINE SYNTHASE; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

EID: 84866719309     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0045705     Document Type: Article
Times cited : (17)

References (59)
  • 1
    • 0035059416 scopus 로고    scopus 로고
    • Cross-presentation, dendritic cells, tolerance and immunity
    • Heath WR, Carbone FR, (2001) Cross-presentation, dendritic cells, tolerance and immunity. Annu Rev Immunol 19: 47-64.
    • (2001) Annu Rev Immunol , vol.19 , pp. 47-64
    • Heath, W.R.1    Carbone, F.R.2
  • 2
    • 0033062377 scopus 로고    scopus 로고
    • Mechanisms of exogenous antigen presentation by MHC class I molecules in vitro and in vivo: implications for generating CD8+ T cell responses to infectious agents, tumors, transplants, and vaccines
    • Yewdell JW, Norbury CC, Bennink JR, (1999) Mechanisms of exogenous antigen presentation by MHC class I molecules in vitro and in vivo: implications for generating CD8+ T cell responses to infectious agents, tumors, transplants, and vaccines. Adv Immunol 73: 1-77.
    • (1999) Adv Immunol , vol.73 , pp. 1-77
    • Yewdell, J.W.1    Norbury, C.C.2    Bennink, J.R.3
  • 3
    • 0033458754 scopus 로고    scopus 로고
    • Alternative pathways for processing exogenous and endogenous antigens that can generate peptides for MHC class I-restricted presentation
    • Reimann J, Schirmbeck R, (1999) Alternative pathways for processing exogenous and endogenous antigens that can generate peptides for MHC class I-restricted presentation. Immunol Rev 172: 131-152.
    • (1999) Immunol Rev , vol.172 , pp. 131-152
    • Reimann, J.1    Schirmbeck, R.2
  • 4
    • 34548101966 scopus 로고    scopus 로고
    • A lymphocytic choriomeningitis virus glycoprotein variant that is retained in the endoplasmic reticulum efficiently cross-primes CD8(+) T cell responses
    • Freigang S, Eschli B, Harris N, Geuking M, Quirin K, et al. (2007) A lymphocytic choriomeningitis virus glycoprotein variant that is retained in the endoplasmic reticulum efficiently cross-primes CD8(+) T cell responses. Proc Natl Acad Sci U S A 104: 13426-13431.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 13426-13431
    • Freigang, S.1    Eschli, B.2    Harris, N.3    Geuking, M.4    Quirin, K.5
  • 5
    • 0035106473 scopus 로고    scopus 로고
    • MHC-I-restricted presentation of HIV-1 virion antigens without viral replication
    • Buseyne F, Le Gall S, Boccaccio C, Abastado JP, Lifson JD, et al. (2001) MHC-I-restricted presentation of HIV-1 virion antigens without viral replication. Nat Med 7: 344-349.
    • (2001) Nat Med , vol.7 , pp. 344-349
    • Buseyne, F.1    Le Gall, S.2    Boccaccio, C.3    Abastado, J.P.4    Lifson, J.D.5
  • 6
    • 0029845430 scopus 로고    scopus 로고
    • Virus-like particles induce MHC class I-restricted T-cell responses. Lessons learned from the hepatitis B small surface antigen
    • Schirmbeck R, Bohm W, Reimann J, (1996) Virus-like particles induce MHC class I-restricted T-cell responses. Lessons learned from the hepatitis B small surface antigen. Intervirology 39: 111-119.
    • (1996) Intervirology , vol.39 , pp. 111-119
    • Schirmbeck, R.1    Bohm, W.2    Reimann, J.3
  • 7
    • 0030273342 scopus 로고    scopus 로고
    • MHC class I-restricted CTL responses to exogenous antigens
    • Jondal M, Schirmbeck R, Reimann J, (1996) MHC class I-restricted CTL responses to exogenous antigens. Immunity 5: 295-302.
    • (1996) Immunity , vol.5 , pp. 295-302
    • Jondal, M.1    Schirmbeck, R.2    Reimann, J.3
  • 8
    • 12344328544 scopus 로고    scopus 로고
    • Access of soluble antigens to the endoplasmic reticulum can explain cross-presentation by dendritic cells
    • Ackerman AL, Kyritsis C, Tampé R, Cresswell P, (2005) Access of soluble antigens to the endoplasmic reticulum can explain cross-presentation by dendritic cells. Nat Immunol 6: 107-113.
    • (2005) Nat Immunol , vol.6 , pp. 107-113
    • Ackerman, A.L.1    Kyritsis, C.2    Tampé, R.3    Cresswell, P.4
  • 9
    • 23244440946 scopus 로고    scopus 로고
    • Cross-presentation of the long-lived lymphocytic choriomeningitis virus nucleoprotein does not require neosynthesis and is enhanced via heat shock proteins
    • Basta S, Stoessel R, Basler M, van den Broek M, Groettrup M, (2005) Cross-presentation of the long-lived lymphocytic choriomeningitis virus nucleoprotein does not require neosynthesis and is enhanced via heat shock proteins. J Immunol 175: 796-805.
    • (2005) J Immunol , vol.175 , pp. 796-805
    • Basta, S.1    Stoessel, R.2    Basler, M.3    van den Broek, M.4    Groettrup, M.5
  • 12
    • 1542357672 scopus 로고    scopus 로고
    • Cellular protein is the source of cross-priming antigen in vivo
    • Shen L, Rock KL, (2004) Cellular protein is the source of cross-priming antigen in vivo. Proc Natl Acad Sci U S A 101: 3035-3040.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 3035-3040
    • Shen, L.1    Rock, K.L.2
  • 13
    • 67149133632 scopus 로고    scopus 로고
    • Heat shock proteins and immune system
    • Tsan MF, Gao B, (2009) Heat shock proteins and immune system. J Leukoc Biol 85: 905-910.
    • (2009) J Leukoc Biol , vol.85 , pp. 905-910
    • Tsan, M.F.1    Gao, B.2
  • 14
    • 34948820602 scopus 로고    scopus 로고
    • Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
    • Apetoh L, Ghiringhelli F, Tesniere A, Obeid M, Ortiz C, et al. (2007) Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med 13: 1050-1059.
    • (2007) Nat Med , vol.13 , pp. 1050-1059
    • Apetoh, L.1    Ghiringhelli, F.2    Tesniere, A.3    Obeid, M.4    Ortiz, C.5
  • 15
    • 0034073872 scopus 로고    scopus 로고
    • Immunostimulatory DNA-based vaccines induce cytotoxic lymphocyte activity by a T-helper cell-independent mechanism
    • Cho HJ, Takabayashi K, Cheng PM, Nguyen MD, Corr M, et al. (2000) Immunostimulatory DNA-based vaccines induce cytotoxic lymphocyte activity by a T-helper cell-independent mechanism. Nat Biotechnol 18: 509-514.
    • (2000) Nat Biotechnol , vol.18 , pp. 509-514
    • Cho, H.J.1    Takabayashi, K.2    Cheng, P.M.3    Nguyen, M.D.4    Corr, M.5
  • 16
    • 15444378922 scopus 로고    scopus 로고
    • Protective CD8 T cell immunity triggered by CpG-protein conjugates competes with the efficacy of live vaccines
    • Heit A, Schmitz F, O'Keeffe M, Staib C, Busch DH, et al. (2005) Protective CD8 T cell immunity triggered by CpG-protein conjugates competes with the efficacy of live vaccines. J Immunol 174: 4373-4380.
    • (2005) J Immunol , vol.174 , pp. 4373-4380
    • Heit, A.1    Schmitz, F.2    O'Keeffe, M.3    Staib, C.4    Busch, D.H.5
  • 17
    • 0242495551 scopus 로고    scopus 로고
    • Antigenic epitopes fused to cationic peptide bound to oligonucleotides facilitate Toll-like receptor 9-dependent, but CD4+ T cell help-independent, priming of CD8+ T cells
    • Schirmbeck R, Riedl P, Zurbriggen R, Akira S, Reimann J, (2003) Antigenic epitopes fused to cationic peptide bound to oligonucleotides facilitate Toll-like receptor 9-dependent, but CD4+ T cell help-independent, priming of CD8+ T cells. J Immunol 171: 5198-5207.
    • (2003) J Immunol , vol.171 , pp. 5198-5207
    • Schirmbeck, R.1    Riedl, P.2    Zurbriggen, R.3    Akira, S.4    Reimann, J.5
  • 18
    • 27244443079 scopus 로고    scopus 로고
    • HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates
    • Wille-Reece U, Flynn BJ, Lore K, Koup RA, Kedl RM, et al. (2005) HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates. Proc Natl Acad Sci U S A 102: 15190-15194.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 15190-15194
    • Wille-Reece, U.1    Flynn, B.J.2    Lore, K.3    Koup, R.A.4    Kedl, R.M.5
  • 19
    • 1642566566 scopus 로고    scopus 로고
    • Nonmethylated CG motifs packaged into virus-like particles induce protective cytotoxic T cell responses in the absence of systemic side effects
    • Storni T, Ruedl C, Schwarz K, Schwendener RA, Renner WA, et al. (2004) Nonmethylated CG motifs packaged into virus-like particles induce protective cytotoxic T cell responses in the absence of systemic side effects. J Immunol 172: 1777-1785.
    • (2004) J Immunol , vol.172 , pp. 1777-1785
    • Storni, T.1    Ruedl, C.2    Schwarz, K.3    Schwendener, R.A.4    Renner, W.A.5
  • 20
    • 34247334988 scopus 로고    scopus 로고
    • TLR ligands differentially affect uptake and presentation of cellular antigens
    • Weck MM, Grunebach F, Werth D, Sinzger C, Bringmann A, et al. (2007) TLR ligands differentially affect uptake and presentation of cellular antigens. Blood 109: 3890-3894.
    • (2007) Blood , vol.109 , pp. 3890-3894
    • Weck, M.M.1    Grunebach, F.2    Werth, D.3    Sinzger, C.4    Bringmann, A.5
  • 21
    • 0029862025 scopus 로고    scopus 로고
    • Humoral immune response against lipopolysaccharide and cytoplasmic proteins of Brucella abortus in cattle vaccinated with B. abortus S19 or experimentally infected with Yersinia enterocolitica serotype 0:9
    • Baldi PC, Giambartolomei GH, Goldbaum FA, Abdon LF, Velikovsky CA, et al. (1996) Humoral immune response against lipopolysaccharide and cytoplasmic proteins of Brucella abortus in cattle vaccinated with B. abortus S19 or experimentally infected with Yersinia enterocolitica serotype 0:9. Clin Diagn Lab Immunol 3: 472-476.
    • (1996) Clin Diagn Lab Immunol , vol.3 , pp. 472-476
    • Baldi, P.C.1    Giambartolomei, G.H.2    Goldbaum, F.A.3    Abdon, L.F.4    Velikovsky, C.A.5
  • 22
    • 0027198208 scopus 로고
    • Characterization of an 18-kilodalton Brucella cytoplasmic protein which appears to be a serological marker of active infection of both human and bovine brucellosis
    • Goldbaum FA, Leoni J, Wallach JC, Fossati CA, (1993) Characterization of an 18-kilodalton Brucella cytoplasmic protein which appears to be a serological marker of active infection of both human and bovine brucellosis. J Clin Microbiol 31: 2141-2145.
    • (1993) J Clin Microbiol , vol.31 , pp. 2141-2145
    • Goldbaum, F.A.1    Leoni, J.2    Wallach, J.C.3    Fossati, C.A.4
  • 23
    • 0141780959 scopus 로고    scopus 로고
    • Brucella lumazine synthase elicits a mixed Th1-Th2 immune response and reduces infection in mice challenged with Brucella abortus 544 independently of the adjuvant formulation used
    • Velikovsky CA, Goldbaum FA, Cassataro J, Estein S, Bowden RA, et al. (2003) Brucella lumazine synthase elicits a mixed Th1-Th2 immune response and reduces infection in mice challenged with Brucella abortus 544 independently of the adjuvant formulation used. Infect Immun 71: 5750-5755.
    • (2003) Infect Immun , vol.71 , pp. 5750-5755
    • Velikovsky, C.A.1    Goldbaum, F.A.2    Cassataro, J.3    Estein, S.4    Bowden, R.A.5
  • 24
    • 0036121919 scopus 로고    scopus 로고
    • A DNA vaccine encoding lumazine synthase from Brucella abortus induces protective immunity in BALB/c mice
    • Velikovsky CA, Cassataro J, Giambartolomei GH, Goldbaum FA, Estein S, et al. (2002) A DNA vaccine encoding lumazine synthase from Brucella abortus induces protective immunity in BALB/c mice. Infect Immun 70: 2507-2511.
    • (2002) Infect Immun , vol.70 , pp. 2507-2511
    • Velikovsky, C.A.1    Cassataro, J.2    Giambartolomei, G.H.3    Goldbaum, F.A.4    Estein, S.5
  • 25
    • 20144383493 scopus 로고    scopus 로고
    • Brucella spp. lumazine synthase: a novel antigen delivery system
    • Sciutto E, Toledo A, Cruz C, Rosas G, Meneses G, et al. (2005) Brucella spp. lumazine synthase: a novel antigen delivery system. Vaccine 23: 2784-2790.
    • (2005) Vaccine , vol.23 , pp. 2784-2790
    • Sciutto, E.1    Toledo, A.2    Cruz, C.3    Rosas, G.4    Meneses, G.5
  • 26
    • 56949092460 scopus 로고    scopus 로고
    • Brucella spp. lumazine synthase as a bovine rotavirus antigen delivery system
    • Bellido D, Craig PO, Mozgovoj MV, Gonzalez DD, Wigdorovitz A, et al. (2009) Brucella spp. lumazine synthase as a bovine rotavirus antigen delivery system. Vaccine 27: 136-145.
    • (2009) Vaccine , vol.27 , pp. 136-145
    • Bellido, D.1    Craig, P.O.2    Mozgovoj, M.V.3    Gonzalez, D.D.4    Wigdorovitz, A.5
  • 27
    • 0034693388 scopus 로고    scopus 로고
    • Single-shot plasmid DNA intrasplenic immunization for the production of monoclonal antibodies. Persistent expression of DNA
    • Velikovsky CA, Cassataro J, Sanchez M, Fossati CA, Fainboim L, et al. (2000) Single-shot plasmid DNA intrasplenic immunization for the production of monoclonal antibodies. Persistent expression of DNA. J Immunol Methods 244: 1-7.
    • (2000) J Immunol Methods , vol.244 , pp. 1-7
    • Velikovsky, C.A.1    Cassataro, J.2    Sanchez, M.3    Fossati, C.A.4    Fainboim, L.5
  • 28
    • 10344256120 scopus 로고    scopus 로고
    • Engineering of a polymeric bacterial protein as a scaffold for the multiple display of peptides
    • Laplagne DA, Zylberman V, Ainciart N, Steward MW, Sciutto E, et al. (2004) Engineering of a polymeric bacterial protein as a scaffold for the multiple display of peptides. Proteins 57: 820-828.
    • (2004) Proteins , vol.57 , pp. 820-828
    • Laplagne, D.A.1    Zylberman, V.2    Ainciart, N.3    Steward, M.W.4    Sciutto, E.5
  • 29
    • 28644447706 scopus 로고    scopus 로고
    • Multiple display of a protein domain on a bacterial polymeric scaffold
    • Craig PO, Berguer PM, Ainciart N, Zylberman V, Thomas MG, et al. (2005) Multiple display of a protein domain on a bacterial polymeric scaffold. Proteins 61: 1089-1100.
    • (2005) Proteins , vol.61 , pp. 1089-1100
    • Craig, P.O.1    Berguer, P.M.2    Ainciart, N.3    Zylberman, V.4    Thomas, M.G.5
  • 30
    • 0034646571 scopus 로고    scopus 로고
    • Divergence in macromolecular assembly: X-ray crystallographic structure analysis of lumazine synthase from Brucella abortus
    • Braden BC, Velikovsky CA, Cauerhff AA, Polikarpov I, Goldbaum FA, (2000) Divergence in macromolecular assembly: X-ray crystallographic structure analysis of lumazine synthase from Brucella abortus. J Mol Biol 297: 1031-1036.
    • (2000) J Mol Biol , vol.297 , pp. 1031-1036
    • Braden, B.C.1    Velikovsky, C.A.2    Cauerhff, A.A.3    Polikarpov, I.4    Goldbaum, F.A.5
  • 31
    • 1542379660 scopus 로고    scopus 로고
    • High order quaternary arrangement confers increased structural stability to Brucella sp. lumazine synthase
    • Zylberman V, Craig PO, Klinke S, Braden BC, Cauerhff A, et al. (2004) High order quaternary arrangement confers increased structural stability to Brucella sp. lumazine synthase. J Biol Chem 279: 8093-8101.
    • (2004) J Biol Chem , vol.279 , pp. 8093-8101
    • Zylberman, V.1    Craig, P.O.2    Klinke, S.3    Braden, B.C.4    Cauerhff, A.5
  • 32
    • 32044471572 scopus 로고    scopus 로고
    • A polymeric bacterial protein activates dendritic cells via TLR4
    • Berguer PM, Mundiñano J, Piazzon I, Goldbaum FA, (2006) A polymeric bacterial protein activates dendritic cells via TLR4. J Immunol 176: 2366-2372.
    • (2006) J Immunol , vol.176 , pp. 2366-2372
    • Berguer, P.M.1    Mundiñano, J.2    Piazzon, I.3    Goldbaum, F.A.4
  • 34
    • 0003633755 scopus 로고    scopus 로고
    • Institute of Laboratory Animal Resources, National Academy Press, Washington DC
    • Institute of Laboratory Animal Resources (1996) Guide for the care and use of laboratory animals. National Academy Press, Washington DC.
    • (1996) Guide for the care and use of laboratory animals
  • 35
    • 0032877992 scopus 로고    scopus 로고
    • The 18-kDa cytoplasmic protein of Brucella species -an antigen useful for diagnosis-is a lumazine synthase
    • Goldbaum FA, Velikovsky CA, Baldi PC, Mortl S, Bacher A, et al. (1999) The 18-kDa cytoplasmic protein of Brucella species -an antigen useful for diagnosis-is a lumazine synthase. J Med Microbiol 48: 833-839.
    • (1999) J Med Microbiol , vol.48 , pp. 833-839
    • Goldbaum, F.A.1    Velikovsky, C.A.2    Baldi, P.C.3    Mortl, S.4    Bacher, A.5
  • 36
    • 0034699367 scopus 로고    scopus 로고
    • Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution
    • Lyons AB, (2000) Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution. J Immunol Methods 243: 147-154.
    • (2000) J Immunol Methods , vol.243 , pp. 147-154
    • Lyons, A.B.1
  • 37
    • 0034548713 scopus 로고    scopus 로고
    • In vivo cross-presentation of a soluble protein antigen: kinetics, distribution, and generation of effector CTL recognizing dominant and subdominant epitopes
    • Nelson D, Bundell C, Robinson B, (2000) In vivo cross-presentation of a soluble protein antigen: kinetics, distribution, and generation of effector CTL recognizing dominant and subdominant epitopes. J Immunol 165: 6123-6132.
    • (2000) J Immunol , vol.165 , pp. 6123-6132
    • Nelson, D.1    Bundell, C.2    Robinson, B.3
  • 38
    • 0141449974 scopus 로고    scopus 로고
    • CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses
    • Suvas S, Kumaraguru U, Pack CD, Lee S, Rouse BT, (2003) CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses. J Exp Med 198: 889-901.
    • (2003) J Exp Med , vol.198 , pp. 889-901
    • Suvas, S.1    Kumaraguru, U.2    Pack, C.D.3    Lee, S.4    Rouse, B.T.5
  • 39
    • 40749151913 scopus 로고    scopus 로고
    • Antigen delivered by anthrax lethal toxin induces the development of memory CD8+ T cells that can be rapidly boosted and display effector functions
    • Shaw CA, Starnbach MN, (2008) Antigen delivered by anthrax lethal toxin induces the development of memory CD8+ T cells that can be rapidly boosted and display effector functions. Infect Immun 76: 1214-1222.
    • (2008) Infect Immun , vol.76 , pp. 1214-1222
    • Shaw, C.A.1    Starnbach, M.N.2
  • 40
    • 1842681952 scopus 로고    scopus 로고
    • Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets
    • Huster KM, Busch V, Schiemann M, Linkemann K, Kerksiek KM, et al. (2004) Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets. Proc Natl Acad Sci U S A 101: 5610-5615.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 5610-5615
    • Huster, K.M.1    Busch, V.2    Schiemann, M.3    Linkemann, K.4    Kerksiek, K.M.5
  • 41
    • 0347382593 scopus 로고    scopus 로고
    • Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
    • Kaech SM, Tan JT, Wherry EJ, Konieczny BT, Surh CD, et al. (2003) Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat Immunol 4: 1191-1198.
    • (2003) Nat Immunol , vol.4 , pp. 1191-1198
    • Kaech, S.M.1    Tan, J.T.2    Wherry, E.J.3    Konieczny, B.T.4    Surh, C.D.5
  • 42
  • 43
    • 0038655228 scopus 로고    scopus 로고
    • Cytokine control of memory T-cell development and survival
    • Schluns KS, Lefrancois L, (2003) Cytokine control of memory T-cell development and survival. Nat Rev Immunol 3: 269-279.
    • (2003) Nat Rev Immunol , vol.3 , pp. 269-279
    • Schluns, K.S.1    Lefrancois, L.2
  • 44
    • 0020285790 scopus 로고
    • Evidence for a major cluster of lymphocyte differentiation antigens on murine chromosome 2
    • Meruelo D, Offer M, Rossomando A, (1982) Evidence for a major cluster of lymphocyte differentiation antigens on murine chromosome 2. Proc Natl Acad Sci U S A 79: 7460-7464.
    • (1982) Proc Natl Acad Sci U S A , vol.79 , pp. 7460-7464
    • Meruelo, D.1    Offer, M.2    Rossomando, A.3
  • 45
    • 0023860826 scopus 로고
    • Characterization of an anti-Ly-6 monoclonal antibody which defines and activates cytolytic T lymphocytes
    • Havran WL, Lancki DW, Moldwin RL, Dialynas DP, Fitch FW, (1988) Characterization of an anti-Ly-6 monoclonal antibody which defines and activates cytolytic T lymphocytes. J Immunol 140: 1034-1042.
    • (1988) J Immunol , vol.140 , pp. 1034-1042
    • Havran, W.L.1    Lancki, D.W.2    Moldwin, R.L.3    Dialynas, D.P.4    Fitch, F.W.5
  • 46
    • 0034087703 scopus 로고    scopus 로고
    • Genetic evidence for the role of the Lv locus in early susceptibility but not IL-10 synthesis in experimental coccidioidomycosis in C57BL mice
    • Fierer J, Walls L, Kirkland TN, (2000) Genetic evidence for the role of the Lv locus in early susceptibility but not IL-10 synthesis in experimental coccidioidomycosis in C57BL mice. J Infect Dis 181: 681-685.
    • (2000) J Infect Dis , vol.181 , pp. 681-685
    • Fierer, J.1    Walls, L.2    Kirkland, T.N.3
  • 47
    • 77951684508 scopus 로고    scopus 로고
    • Shaping Successful and Unsuccessful CD8 T Cell Responses Following Infection
    • Cox MA, Zajac AJ, (2010) Shaping Successful and Unsuccessful CD8 T Cell Responses Following Infection. J Biomed Biotechnol DOI:10.1155/2010/159152.
    • (2010) J Biomed Biotechnol
    • Cox, M.A.1    Zajac, A.J.2
  • 48
    • 84856354852 scopus 로고    scopus 로고
    • An alternative signal 3: CD8+ T cell memory independent of IL-12 and type I IFN is dependent on CD27/OX40 signaling
    • Sanchez PJ, Kedl RM, (2012) An alternative signal 3: CD8+ T cell memory independent of IL-12 and type I IFN is dependent on CD27/OX40 signaling. Vaccine 30: 1154-1161.
    • (2012) Vaccine , vol.30 , pp. 1154-1161
    • Sanchez, P.J.1    Kedl, R.M.2
  • 49
    • 0035903326 scopus 로고    scopus 로고
    • Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
    • Hawiger D, Inaba K, Dorsett Y, Guo M, Mahnke K, et al. (2001) Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med 194: 769-779.
    • (2001) J Exp Med , vol.194 , pp. 769-779
    • Hawiger, D.1    Inaba, K.2    Dorsett, Y.3    Guo, M.4    Mahnke, K.5
  • 50
    • 0037122011 scopus 로고    scopus 로고
    • Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance
    • Bonifaz L, Bonnyay D, Mahnke K, Rivera M, Nussenzweig MC, et al. (2002) Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J Exp Med 196: 1627-1638.
    • (2002) J Exp Med , vol.196 , pp. 1627-1638
    • Bonifaz, L.1    Bonnyay, D.2    Mahnke, K.3    Rivera, M.4    Nussenzweig, M.C.5
  • 52
    • 2342525996 scopus 로고    scopus 로고
    • Regulation of phagosome maturation by signals from toll-like receptors
    • Blander JM, Medzhitov R, (2004) Regulation of phagosome maturation by signals from toll-like receptors. Science 304: 1014-1018.
    • (2004) Science , vol.304 , pp. 1014-1018
    • Blander, J.M.1    Medzhitov, R.2
  • 53
    • 33645734929 scopus 로고    scopus 로고
    • Toll-dependent selection of microbial antigens for presentation by dendritic cells
    • Blander JM, Medzhitov R, (2006) Toll-dependent selection of microbial antigens for presentation by dendritic cells. Nature 440: 808-812.
    • (2006) Nature , vol.440 , pp. 808-812
    • Blander, J.M.1    Medzhitov, R.2
  • 54
    • 33748879305 scopus 로고    scopus 로고
    • Toll-like receptor recognition regulates immunodominance in an antimicrobial CD4+ T cell response
    • Yarovinsky F, Kanzler H, Hieny S, Coffman RL, Sher A, (2006) Toll-like receptor recognition regulates immunodominance in an antimicrobial CD4+ T cell response. Immunity 25: 655-664.
    • (2006) Immunity , vol.25 , pp. 655-664
    • Yarovinsky, F.1    Kanzler, H.2    Hieny, S.3    Coffman, R.L.4    Sher, A.5
  • 55
    • 74249107488 scopus 로고    scopus 로고
    • Innate signaling regulates cross-priming at the level of DC licensing and not antigen presentation
    • Keller SA, Schwarz K, Manolova V, von Allmen CE, Kinzler MG, et al. (2010) Innate signaling regulates cross-priming at the level of DC licensing and not antigen presentation. Eur J Immunol 40: 103-112.
    • (2010) Eur J Immunol , vol.40 , pp. 103-112
    • Keller, S.A.1    Schwarz, K.2    Manolova, V.3    von Allmen, C.E.4    Kinzler, M.G.5
  • 56
    • 78049511069 scopus 로고    scopus 로고
    • The capacity to induce cross-presentation dictates the success of a TLR7 agonist-conjugate vaccine for eliciting cellular immunity
    • Oh JZ, Kedl RM, (2010) The capacity to induce cross-presentation dictates the success of a TLR7 agonist-conjugate vaccine for eliciting cellular immunity. J Immunol 185: 4602-4608.
    • (2010) J Immunol , vol.185 , pp. 4602-4608
    • Oh, J.Z.1    Kedl, R.M.2
  • 57
    • 0030865632 scopus 로고    scopus 로고
    • Peptide-induced deletion of CD8 T cells in vivo occurs via apoptosis in situ
    • Koniaras C, Bennett SR, Carbone FR, Heath WR, Lew AM, (1997) Peptide-induced deletion of CD8 T cells in vivo occurs via apoptosis in situ. Int Immunol 9: 1601-1605.
    • (1997) Int Immunol , vol.9 , pp. 1601-1605
    • Koniaras, C.1    Bennett, S.R.2    Carbone, F.R.3    Heath, W.R.4    Lew, A.M.5
  • 58
    • 0037108790 scopus 로고    scopus 로고
    • Class I negative CD8 T cells reveal the confounding role of peptide-transfer onto CD8 T cells stimulated with soluble H2-Kb molecules
    • Schott E, Bertho N, Ge Q, Maurice MM, Ploegh HL, (2002) Class I negative CD8 T cells reveal the confounding role of peptide-transfer onto CD8 T cells stimulated with soluble H2-Kb molecules. Proc Natl Acad Sci U S A 99: 13735-13740.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 13735-13740
    • Schott, E.1    Bertho, N.2    Ge, Q.3    Maurice, M.M.4    Ploegh, H.L.5
  • 59
    • 38449106129 scopus 로고    scopus 로고
    • CD8+ CTL priming by exact peptide epitopes in incomplete Freund's adjuvant induces a vanishing CTL response, whereas long peptides induce sustained CTL reactivity
    • Bijker MS, van den Eeden SJ, Franken KL, Melief CJ, Offringa R, et al. (2007) CD8+ CTL priming by exact peptide epitopes in incomplete Freund's adjuvant induces a vanishing CTL response, whereas long peptides induce sustained CTL reactivity. J Immunol 179: 5033-5040.
    • (2007) J Immunol , vol.179 , pp. 5033-5040
    • Bijker, M.S.1    van den Eeden, S.J.2    Franken, K.L.3    Melief, C.J.4    Offringa, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.