메뉴 건너뛰기




Volumn 9, Issue 4, 2012, Pages 425-436

Protein biomarkers of alcohol abuse

Author keywords

alcohol abuse and dependence; biomarkers; DIGE; ethanol; mass spectrometry; proteomics

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; 5 HYDROXYTRYPTOPHOL; ACETALDEHYDE; ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; BETA N ACETYLHEXOSAMINIDASE; BIOLOGICAL MARKER; CARBOHYDRATE DEFICIENT TRANSFERRIN; CYTOKINE; ETHYL GLUCURONIDE; GAMMA GLUTAMYLTRANSFERASE; PHOSPHATIDYLETHANOLAMINE; PROTEIN; SIALIC ACID;

EID: 84866315167     PISSN: 14789450     EISSN: 17448387     Source Type: Journal    
DOI: 10.1586/epr.12.38     Document Type: Review
Times cited : (27)

References (99)
  • 1
    • 80052758517 scopus 로고    scopus 로고
    • Alcohol consumption and non-communicable diseases: Epidemiology and policy implications
    • Parry CD, Patra J, Rehm J. Alcohol consumption and non-communicable diseases: Epidemiology and policy implications. Addiction 106(10), 1718-1724 (2011).
    • (2011) Addiction , vol.106 , Issue.10 , pp. 1718-1724
    • Parry, C.D.1    Patra, J.2    Rehm, J.3
  • 4
    • 67649116613 scopus 로고    scopus 로고
    • Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders
    • Rehm J, Mathers C, Popova S, Thavorncharoensap M, Teerawattananon Y, Patra J. Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders. Lancet 373(9682), 2223-2233 (2009).
    • (2009) Lancet , vol.373 , Issue.9682 , pp. 2223-2233
    • Rehm, J.1    Mathers, C.2    Popova, S.3    Thavorncharoensap, M.4    Teerawattananon, Y.5    Patra, J.6
  • 6
    • 0021199110 scopus 로고
    • Detecting alcoholism. The CAGE questionnaire
    • DOI 10.1001/jama.252.14.1905
    • Ewing JA. Detecting alcoholism. The CAGE questionnaire. JAMA 252(14), 1905-1907 (1984). (Pubitemid 14002155)
    • (1984) Journal of the American Medical Association , vol.252 , Issue.14 , pp. 1905-1907
    • Ewing, J.A.1
  • 7
    • 77952923654 scopus 로고    scopus 로고
    • Editorial commentary: Alcohol biomarker papers
    • Anton RF. Editorial commentary: Alcohol biomarker papers. Alcohol. Clin. Exp. Res. 34(6), 939-940 (2010).
    • (2010) Alcohol. Clin. Exp. Res. , vol.34 , Issue.6 , pp. 939-940
    • Anton, R.F.1
  • 8
    • 0023918463 scopus 로고
    • Validity of self-report in alcoholism research: Results of a Veterans Administration Cooperative Study
    • Fuller RK, Lee KK, Gordis E. Validity of self-report in alcoholism research: Results of a Veterans Administration Cooperative Study. Alcohol. Clin. Exp. Res. 12(2), 201-205 (1988).
    • (1988) Alcohol. Clin. Exp. Res. , vol.12 , Issue.2 , pp. 201-205
    • Fuller, R.K.1    Lee, K.K.2    Gordis, E.3
  • 9
    • 84866340315 scopus 로고    scopus 로고
    • Review of current clinical biomarkers for the detection of alcohol dependence
    • Tavakoli HR, Hull M, Michael Okasinski L. Review of current clinical biomarkers for the detection of alcohol dependence. Innov. Clin. Neurosci. 8(3), 26-33 (2011).
    • (2011) Innov. Clin. Neurosci. , vol.8 , Issue.3 , pp. 26-33
    • Tavakoli, H.R.1    Hull, M.2    Michael Okasinski, L.3
  • 10
    • 61649089246 scopus 로고    scopus 로고
    • Novel objective biomarkers of alcohol use: Potential diagnostic and treatment management tools in dual diagnosis care
    • Kalapatapu RK, Chambers R. Novel objective biomarkers of alcohol use: potential diagnostic and treatment management tools in dual diagnosis care. J. Dual Diagn. 5(1), 57-82 (2009).
    • (2009) J. Dual Diagn. , vol.5 , Issue.1 , pp. 57-82
    • Kalapatapu, R.K.1    Chambers, R.2
  • 11
    • 77952912527 scopus 로고    scopus 로고
    • Future prospects for biomarkers of alcohol consumption and alcohol-induced disorders
    • Freeman WM, Vrana KE. Future prospects for biomarkers of alcohol consumption and alcohol-induced disorders. Alcohol. Clin. Exp. Res. 34(6), 946-954 (2010).
    • (2010) Alcohol. Clin. Exp. Res. , vol.34 , Issue.6 , pp. 946-954
    • Freeman, W.M.1    Vrana, K.E.2
  • 13
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
    • Biomarkers Working Group. Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin. Pharmacol. Ther. 69(3), 89-95 (2001).
    • (2001) Clin. Pharmacol. Ther. , vol.69 , Issue.3 , pp. 89-95
  • 14
    • 77956112961 scopus 로고    scopus 로고
    • Recommendations for biomarker identification and qualification in clinical proteomics
    • Mischak H, Allmaier G, Apweiler R et al. Recommendations for biomarker identification and qualification in clinical proteomics. Sci. Transl. Med. 2(46), 46ps42 (2010).
    • (2010) Sci. Transl. Med. , vol.2 , Issue.46
    • Mischak, H.1    Allmaier, G.2    Apweiler, R.3
  • 15
    • 38349113522 scopus 로고    scopus 로고
    • Grand rounds in proteomics at the FDA white oak, silver spring, MD, USA, April 3, 2007
    • Goodsaid F, Bandow JE, Mischak H. Grand rounds in proteomics at the FDA white oak, silver spring, MD, USA, April 3, 2007. Proteomics. Clin. Appl. 1(12), 1526-1531 (2007).
    • (2007) Proteomics. Clin. Appl. , vol.1 , Issue.12 , pp. 1526-1531
    • Goodsaid, F.1    Bandow, J.E.2    Mischak, H.3
  • 16
    • 0346964414 scopus 로고    scopus 로고
    • Self-report and biochemical measures of alcohol consumption
    • Litten RZ, Fertig J. Self-report and biochemical measures of alcohol consumption. Addiction 98(Suppl. 2), iii-iiv (2003).
    • (2003) Addiction , vol.98 , Issue.SUPPL. 2
    • Litten, R.Z.1    Fertig, J.2
  • 17
    • 77952931598 scopus 로고    scopus 로고
    • Alcohol biomarkers in applied settings: Recent advances and future research opportunities
    • Litten RZ, Bradley AM, Moss HB. Alcohol biomarkers in applied settings: Recent advances and future research opportunities. Alcohol. Clin. Exp. Res. 34(6), 955-967 (2010).
    • (2010) Alcohol. Clin. Exp. Res. , vol.34 , Issue.6 , pp. 955-967
    • Litten, R.Z.1    Bradley, A.M.2    Moss, H.B.3
  • 18
    • 84865092441 scopus 로고    scopus 로고
    • Determination of maternal-fetal biomarkers of prenatal exposure to ethanol: A review
    • Joya X, Friguls B, Ortigosa S et al. Determination of maternal-fetal biomarkers of prenatal exposure to ethanol: A review. J. Pharm. Biomed. Anal. 69, 209-222 (2012).
    • (2012) J. Pharm. Biomed. Anal. , vol.69 , pp. 209-222
    • Joya, X.1    Friguls, B.2    Ortigosa, S.3
  • 20
    • 33845400236 scopus 로고    scopus 로고
    • Biomarkers in alcoholism
    • Niemelä O. Biomarkers in alcoholism. Clin. Chim. Acta 377(1-2), 39-49 (2007).
    • (2007) Clin. Chim. Acta , vol.377 , Issue.1-2 , pp. 39-49
    • Niemela, O.1
  • 21
    • 47149087864 scopus 로고    scopus 로고
    • Ethylglucuronide as a biomarker for ethanol detection
    • DOI 10.1592/phco.28.6.769
    • Kissack JC, Bishop J, Roper AL. Ethylglucuronide as a biomarker for ethanol detection. Pharmacotherapy 28(6), 769-781 (2008). (Pubitemid 351975380)
    • (2008) Pharmacotherapy , vol.28 , Issue.6 , pp. 769-781
    • Kissack, J.C.1    Bishop, J.2    Leatherwood Roper, A.3
  • 22
    • 85042617232 scopus 로고    scopus 로고
    • Detection times for urinary ethyl glucuronide and ethyl sulfate in heavy drinkers during alcohol detoxification
    • Helander A, Böttcher M, Fehr C, Dahmen N, Beck O. Detection times for urinary ethyl glucuronide and ethyl sulfate in heavy drinkers during alcohol detoxification. Alcohol Alcohol. 44(1), 55-61 (2009).
    • (2009) Alcohol Alcohol , vol.44 , Issue.1 , pp. 55-61
    • Helander, A.1    Böttcher, M.2    Fehr, C.3    Dahmen, N.4    Beck, O.5
  • 24
    • 64649091424 scopus 로고    scopus 로고
    • Ethyl glucuronide in hair compared with traditional alcohol biomarkers - A pilot study of heavy drinkers referred to an alcohol detoxification unit
    • Høiseth G, Morini L, Polettini A, Christophersen A, Mørland J. Ethyl glucuronide in hair compared with traditional alcohol biomarkers - a pilot study of heavy drinkers referred to an alcohol detoxification unit. Alcohol. Clin. Exp. Res. 33(5), 812-816 (2009).
    • (2009) Alcohol. Clin. Exp. Res. , vol.33 , Issue.5 , pp. 812-816
    • Høiseth, G.1    Morini, L.2    Polettini, A.3    Christophersen, A.4    Mørland, J.5
  • 26
    • 84858699433 scopus 로고    scopus 로고
    • Determination of ethyl glucuronide in nails by liquid chromatography tandem mass spectrometry as a potential new biomarker for chronic alcohol abuse and binge drinking behavior
    • Morini L, Colucci M, Ruberto MG, Groppi A. Determination of ethyl glucuronide in nails by liquid chromatography tandem mass spectrometry as a potential new biomarker for chronic alcohol abuse and binge drinking behavior. Anal. Bioanal. Chem. 402(5), 1865-1870 (2012).
    • (2012) Anal. Bioanal. Chem. , vol.402 , Issue.5 , pp. 1865-1870
    • Morini, L.1    Colucci, M.2    Ruberto, M.G.3    Groppi, A.4
  • 27
    • 65549109873 scopus 로고    scopus 로고
    • Urinary ethyl glucuronide (EtG) and ethyl sulphate (EtS) assessment: Valuable tools to improve verification of abstention in alcohol-dependent patients during in-patient treatment and at follow-ups
    • Junghanns K, Graf I, Pflüger J et al. Urinary ethyl glucuronide (EtG) and ethyl sulphate (EtS) assessment: Valuable tools to improve verification of abstention in alcohol-dependent patients during in-patient treatment and at follow-ups. Addiction 104(6), 921-926 (2009).
    • (2009) Addiction , vol.104 , Issue.6 , pp. 921-926
    • Junghanns, K.1    Graf, I.2    Pflüger, J.3
  • 28
    • 23944442971 scopus 로고    scopus 로고
    • Ethyl sulfate: A metabolite of ethanol in humans and a potential biomarker of acute alcohol intake
    • Helander A, Beck O. Ethyl sulfate: A metabolite of ethanol in humans and a potential biomarker of acute alcohol intake. J. Anal. Toxicol. 29(5), 270-274 (2005). (Pubitemid 41191694)
    • (2005) Journal of Analytical Toxicology , vol.29 , Issue.5 , pp. 270-274
    • Helander, A.1    Beck, O.2
  • 29
    • 0346199332 scopus 로고    scopus 로고
    • Current status of carbohydrate deficient transferrin, total serum sialic acid sialic acid index of apolipoprotein J and serum beta hexosaminidase as markers for alcohol consumption
    • Javors MA, Johnson BA. Current status of carbohydrate deficient transferrin, total serum sialic acid, sialic acid index of apolipoprotein J and serum beta hexosaminidase as markers for alcohol consumption. Addiction 98(Suppl. 2), 45-50 (2003).
    • (2003) Addiction , pp. 45-50
    • Javors, M.A.1    Johnson, B.A.2
  • 32
    • 35648986612 scopus 로고    scopus 로고
    • Relationship between serum sialic acid and sialylated glycoproteins in alcoholics
    • DOI 10.1093/alcalc/agm048
    • Chrostek L, Cylwik B, Krawiec A, Korcz W, Szmitkowski M. Relationship between serum sialic acid and sialylated glycoproteins in alcoholics. Alcohol Alcohol. 42(6), 588-592 (2007). (Pubitemid 350028202)
    • (2007) Alcohol and Alcoholism , vol.42 , Issue.6 , pp. 588-592
    • Chrostek, L.1    Cylwik, B.2    Krawiec, A.3    Korcz, W.4    Szmitkowski, M.5
  • 33
    • 13844256547 scopus 로고    scopus 로고
    • The effects of alcohol and smoking on serum, saliva, and urine sialic acid levels
    • Kurtul N, Cil MY, Bakan E. The effects of alcohol and smoking on serum, saliva, and urine sialic acid levels. Saudi Med. J. 25(12), 1839-1844 (2004). (Pubitemid 40253652)
    • (2004) Saudi Medical Journal , vol.25 , Issue.12 , pp. 1839-1844
    • Kurtul, N.1    Cil, M.Y.2    Bakan, E.3
  • 34
    • 78650122796 scopus 로고    scopus 로고
    • Estimation and comparative study of serum total sialic acid levels as tumor markers in oral cancer and precancer
    • Joshi M, Patil R. Estimation and comparative study of serum total sialic acid levels as tumor markers in oral cancer and precancer. J. Cancer Res. Ther. 6(3), 263-266 (2010).
    • (2010) J. Cancer Res. Ther. , vol.6 , Issue.3 , pp. 263-266
    • Joshi, M.1    Patil, R.2
  • 35
    • 84863445642 scopus 로고    scopus 로고
    • A comparison of the effect of glitazones on serum sialic acid in patients with Type 2 diabetes
    • Ur Rahman I, Idrees M, Salman M et al. A comparison of the effect of glitazones on serum sialic acid in patients with Type 2 diabetes. Diab. Vasc. Dis. Res. 9(3), 238-240 (2012).
    • (2012) Diab. Vasc. Dis. Res. , vol.9 , Issue.3 , pp. 238-240
    • Ur Rahman, I.1    Idrees, M.2    Salman, M.3
  • 37
    • 64649092110 scopus 로고    scopus 로고
    • Serum sialic acid changes in non-insulin-dependant diabetes mellitus (NIDDM) patients following bitter melon (Momordica charantia) and rosiglitazone (Avandia) treatment
    • Inayat Ur R, Malik SA, Bashir M, Khan R, Iqbal M. Serum sialic acid changes in non-insulin-dependant diabetes mellitus (NIDDM) patients following bitter melon (Momordica charantia) and rosiglitazone (Avandia) treatment. Phytomedicine 16(5), 401-405 (2009).
    • (2009) Phytomedicine , vol.16 , Issue.5 , pp. 401-405
    • Inayat Ur, R.1    Malik, S.A.2    Bashir, M.3    Khan, R.4    Iqbal, M.5
  • 38
  • 39
    • 0348090617 scopus 로고    scopus 로고
    • 5-Hydroxytryptophol as a marker for recent alcohol intake
    • DOI 10.1046/j.1359-6357.2003.00583.x
    • Beck O, Helander A. 5-hydroxytryptophol as a marker for recent alcohol intake. Addiction 98(Suppl. 2), 63-72 (2003). (Pubitemid 38030763)
    • (2003) Addiction , vol.98 , Issue.SUPPL. 2 , pp. 63-72
    • Beck, O.1    Helander, A.2
  • 40
    • 0035995992 scopus 로고    scopus 로고
    • WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence Investigators. Laboratory tests for acute alcohol consumption: Results of the WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence
    • Helander A, Eriksson CJ; WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence Investigators. Laboratory tests for acute alcohol consumption: Results of the WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence. Alcohol. Clin. Exp. Res. 26(7), 1070-1077 (2002).
    • (2002) Alcohol. Clin. Exp. Res. , vol.26 , Issue.7 , pp. 1070-1077
    • Helander, A.1    Eriksson, C.J.2
  • 42
    • 18844384624 scopus 로고    scopus 로고
    • Detection of recent ethanol intake with new markers: Comparison of fatty acid ethyl esters in serum and of ethyl glucuronide and the ratio of 5-hydroxytryptophol to 5-hydroxyindole acetic acid in urine
    • DOI 10.1097/01.ALC.0000164372.67018.EA
    • Borucki K, Schreiner R, Dierkes J et al. Detection of recent ethanol intake with new markers: Comparison of fatty acid ethyl esters in serum and of ethyl glucuronide and the ratio of 5-hydroxytryptophol to 5-hydroxyindole acetic acid in urine. Alcohol. Clin. Exp. Res. 29(5), 781-787 (2005). (Pubitemid 40686548)
    • (2005) Alcoholism: Clinical and Experimental Research , vol.29 , Issue.5 , pp. 781-787
    • Borucki, K.1    Schreiner, R.2    Dierkes, J.3    Jachau, K.4    Krause, D.5    Westphal, S.6    Wurst, F.M.7    Luley, C.8    Schmidt-Gayk, H.9
  • 43
    • 79954792504 scopus 로고    scopus 로고
    • Phosphatidylethanol in blood (B-PEth): A marker for alcohol use and abuse
    • Isaksson A, Walther L, Hansson T, Andersson A, Alling C. Phosphatidylethanol in blood (B-PEth): A marker for alcohol use and abuse. Drug Test. Anal. 3(4), 195-200 (2011).
    • (2011) Drug Test. Anal. , vol.3 , Issue.4 , pp. 195-200
    • Isaksson, A.1    Walther, L.2    Hansson, T.3    Andersson, A.4    Alling, C.5
  • 44
    • 33745684382 scopus 로고    scopus 로고
    • Phosphatidylethanol (PEth) concentrations in blood are correlated to reported alcohol intake in alcohol-dependent patients
    • Aradottir S, Asanovska G, Gjerss S, Hansson P, Alling C. Phosphatidylethanol (PEth) concentrations in blood are correlated to reported alcohol intake in alcohol-dependent patients. Alcohol Alcohol. 41(4), 431-437 (2006).
    • (2006) Alcohol Alcohol , vol.41 , Issue.4 , pp. 431-437
    • Aradottir, S.1    Asanovska, G.2    Gjerss, S.3    Hansson, P.4    Alling, C.5
  • 45
    • 33947182580 scopus 로고    scopus 로고
    • Phosphatidylethanol as a sensitive and specific biomarker - Comparison with gamma-glutamyl transpeptidase, mean corpuscular volume and carbohydrate- deficient transferrin
    • DOI 10.1111/j.1369-1600.2006.00040.x
    • Hartmann S, Aradottir S, Graf M et al. Phosphatidylethanol as a sensitive and specific biomarker: Comparison with gamma-glutamyl transpeptidase, mean corpuscular volume and carbohydratedeficient transferrin. Addict. Biol. 12(1), 81-84 (2007). (Pubitemid 46405993)
    • (2007) Addiction Biology , vol.12 , Issue.1 , pp. 81-84
    • Hartmann, S.1    Aradottir, S.2    Graf, M.3    Wiesbeck, G.4    Lesch, O.5    Ramskogler, K.6    Wolfersdorf, M.7    Alling, C.8    Wurst, F.M.9
  • 47
    • 71949091346 scopus 로고    scopus 로고
    • Phosphatidylethanol: Normalization during detoxification, gender aspects and correlation with other biomarkers and self-reports
    • Wurst FM, Thon N, Aradottir S et al. Phosphatidylethanol: Normalization during detoxification, gender aspects and correlation with other biomarkers and self-reports. Addict. Biol. 15(1), 88-95 (2010).
    • (2010) Addict. Biol. , vol.15 , Issue.1 , pp. 88-95
    • Wurst, F.M.1    Thon, N.2    Aradottir, S.3
  • 50
    • 80054881494 scopus 로고    scopus 로고
    • Comparative evaluation of capillary zone electrophoresis and HPLC in the determination of carbohydrate-deficient transferrin
    • Daves M, Cemin R, Floreani M, Pusceddu I, Cosio G, Lippi G. Comparative evaluation of capillary zone electrophoresis and HPLC in the determination of carbohydrate-deficient transferrin. Clin. Chem. Lab. Med. 49(10), 1677-1680 (2011).
    • (2011) Clin. Chem. Lab. Med. , vol.49 , Issue.10 , pp. 1677-1680
    • Daves, M.1    Cemin, R.2    Floreani, M.3    Pusceddu, I.4    Cosio, G.5    Lippi, G.6
  • 51
    • 47649095038 scopus 로고    scopus 로고
    • HPLC and mass spectrometric characterization of a candidate reference material for the alcohol biomarker carbohydrate-deficient transferrin (CDT)
    • Oberrauch W, Bergman AC, Helander A. HPLC and mass spectrometric characterization of a candidate reference material for the alcohol biomarker carbohydrate-deficient transferrin (CDT). Clin. Chim. Acta 395(1-2), 142-145 (2008).
    • (2008) Clin. Chim. Acta , vol.395 , Issue.1-2 , pp. 142-145
    • Oberrauch, W.1    Bergman, A.C.2    Helander, A.3
  • 52
    • 51749090182 scopus 로고    scopus 로고
    • Automated measurement of carbohydrate-deficient transferrin using the Bio-Rad %CDT by the HPLC test on a variant HPLC system: Evaluation and comparison with other routine procedures
    • Schellenberg F, Mennetrey L, Girre C, Nalpas B, Pagès JC. Automated measurement of carbohydrate-deficient transferrin using the Bio-Rad %CDT by the HPLC test on a variant HPLC system: Evaluation and comparison with other routine procedures. Alcohol Alcohol. 43(5), 569-576 (2008).
    • (2008) Alcohol Alcohol , vol.43 , Issue.5 , pp. 569-576
    • Schellenberg, F.1    Mennetrey, L.2    Girre, C.3    Nalpas, B.4    Pagès, J.C.5
  • 53
    • 27644471876 scopus 로고    scopus 로고
    • Carbohydrate-deficient transferrin parallels disease severity in anorexia nervosa
    • DOI 10.1016/j.psychres.2004.04.016, PII S0165178105002179
    • Reif A, Fallgatter AJ, Schmidtke A. Carbohydrate-deficient transferrin parallels disease severity in anorexia nervosa. Psychiatry Res. 137(1-2), 143-146 (2005). (Pubitemid 41550138)
    • (2005) Psychiatry Research , vol.137 , Issue.1-2 , pp. 143-146
    • Reif, A.1    Fallgatter, A.J.2    Schmidtke, A.3
  • 54
    • 78650513424 scopus 로고    scopus 로고
    • Changes in transferrin glycosylation during pregnancy may lead to false-positive carbohydrate-deficient transferrin (CDT) results in testing for riskful alcohol consumption
    • Kenan N, Larsson A, Axelsson O, Helander A. Changes in transferrin glycosylation during pregnancy may lead to false-positive carbohydrate-deficient transferrin (CDT) results in testing for riskful alcohol consumption. Clin. Chim. Acta 412(1-2), 129-133 (2011).
    • (2011) Clin. Chim. Acta , vol.412 , Issue.1-2 , pp. 129-133
    • Kenan, N.1    Larsson, A.2    Axelsson, O.3    Helander, A.4
  • 55
    • 4544275672 scopus 로고    scopus 로고
    • A review of genetic, biological, pharmacological, and clinical factors that affect carbohydrate-deficient transferrin levels
    • DOI 10.1097/01.ALC.0000139815.89794.BE
    • Fleming MF, Anton RF, Spies CD. A review of genetic, biological, pharmacological, and clinical factors that affect carbohydrate-deficient transferrin levels. Alcohol. Clin. Exp. Res. 28(9), 1347-1355 (2004). (Pubitemid 39238293)
    • (2004) Alcoholism: Clinical and Experimental Research , vol.28 , Issue.9 , pp. 1347-1355
    • Fleming, M.F.1    Anton, R.F.2    Spies, C.D.3
  • 56
    • 80755152933 scopus 로고    scopus 로고
    • Analysis of carbohydrate deficient transferrin serum levels during abstinence
    • Ridinger M, Köhl P, Gäbele E et al. Analysis of carbohydrate deficient transferrin serum levels during abstinence. Exp. Mol. Pathol. 92(1), 50-53 (2012).
    • (2012) Exp. Mol. Pathol. , vol.92 , Issue.1 , pp. 50-53
    • Ridinger, M.1    Köhl, P.2    Gäbele, E.3
  • 57
    • 0346829861 scopus 로고    scopus 로고
    • Use of biomarkers for alcohol use disorders in clinical practice
    • DOI 10.1046/j.1359-6357.2003.00587.x
    • Neumann T, Spies C. Use of biomarkers for alcohol use disorders in clinical practice. Addiction 98(Suppl. 2), 81-91 (2003). (Pubitemid 38030765)
    • (2003) Addiction , vol.98 , Issue.SUPPL. 2 , pp. 81-91
    • Neumann, T.1    Spies, C.2
  • 58
    • 76649093921 scopus 로고    scopus 로고
    • Elevated serum gamma glutamyltransferase activity is associated with increased risk of mortality, incident Type 2 diabetes, cardiovascular events, chronic kidney disease and cancer - A narrative review
    • Targher G. Elevated serum gamma glutamyltransferase activity is associated with increased risk of mortality, incident Type 2 diabetes, cardiovascular events, chronic kidney disease and cancer - a narrative review. Clin. Chem. Lab. Med. 48(2), 147-157 (2010).
    • (2010) Clin. Chem. Lab. Med. , vol.48 , Issue.2 , pp. 147-157
    • Targher, G.1
  • 59
    • 0346829864 scopus 로고    scopus 로고
    • Traditional markers of excessive alcohol use
    • DOI 10.1046/j.1359-6357.2003.00581.x
    • Conigrave KM, Davies P, Haber P, Whitfield JB. Traditional markers of excessive alcohol use. Addiction 98(Suppl. 2), 31-43 (2003). (Pubitemid 38030760)
    • (2003) Addiction , vol.98 , Issue.SUPPL. 2 , pp. 31-43
    • Conigrave, K.M.1    Davies, P.2    Haber, P.3    Whitfield, J.B.4
  • 60
    • 0025239791 scopus 로고
    • The effects of moderate drinking and abstinence on serum and urinary -hexosaminidase levels
    • DOI 10.1016/0376-8716(90)90137-4
    • Kärkkäinen P, Jokelainen K, Roine R, Suokas A, Salaspuro M. The effects of moderate drinking and abstinence on serum and urinary beta-hexosaminidase levels. Drug Alcohol Depend. 25(1), 35-38 (1990). (Pubitemid 20086951)
    • (1990) Drug and Alcohol Dependence , vol.25 , Issue.1 , pp. 35-38
    • Karkkainen, P.1    Jokelainen, K.2    Roine, R.3    Soukas, A.4    Salaspuro, M.5
  • 61
    • 0025161417 scopus 로고
    • Serum and urinary -hexosaminidase as markers of heavy drinking
    • Kärkkäinen P. Serum and urinary beta-hexosaminidase as markers of heavy drinking. Alcohol Alcohol. 25(4), 365-369 (1990). (Pubitemid 20285201)
    • (1990) Alcohol and Alcoholism , vol.25 , Issue.4 , pp. 365-369
    • Karkkainen, P.1
  • 62
    • 27744530929 scopus 로고    scopus 로고
    • Biomarkers for alcohol use and abuse: A summary
    • Peterson K. Biomarkers for alcohol use and abuse - a summary. Alcohol Res. Health 28(1), 30-37 (2004). (Pubitemid 41595218)
    • (2004) Alcohol Research and Health , vol.28 , Issue.1 , pp. 30-37
    • Peterson, K.1
  • 63
    • 69449100196 scopus 로고    scopus 로고
    • A new CE-ESI-MS method for the detection of stable hemoglobin acetaldehyde adducts, potential biomarkers of alcohol abuse
    • De Benedetto GE, Fanigliulo M. A new CE-ESI-MS method for the detection of stable hemoglobin acetaldehyde adducts, potential biomarkers of alcohol abuse. Electrophoresis 30(10), 1798-1807 (2009).
    • (2009) Electrophoresis , vol.30 , Issue.10 , pp. 1798-1807
    • De Benedetto, G.E.1    Fanigliulo, M.2
  • 65
    • 33749079901 scopus 로고    scopus 로고
    • IgAs against acetaldehyde-modified red cell protein as a marker of ethanol consumption in male alcoholic subjects, moderate drinkers, and abstainers
    • DOI 10.1111/j.1530-0277.2006.00204.x
    • Hietala J, Koivisto H, Latvala J, Anttila P, Niemelä O. IgAs against acetaldehydemodified red cell protein as a marker of ethanol consumption in male alcoholic subjects, moderate drinkers, and abstainers. Alcohol. Clin. Exp. Res. 30(10), 1693-1698 (2006). (Pubitemid 44465608)
    • (2006) Alcoholism: Clinical and Experimental Research , vol.30 , Issue.10 , pp. 1693-1698
    • Hietala, J.1    Koivisto, H.2    Latvala, J.3    Anttila, P.4    Niemela, O.5
  • 66
    • 0035711126 scopus 로고    scopus 로고
    • Plasma sialic-acid index of apolipoprotein J (SIJ): A new alcohol intake marker
    • DOI 10.1016/S0741-8329(01)00187-2, PII S0741832901001872
    • Ghosh P, Hale EA, Lakshman MR. Plasma sialic-acid index of apolipoprotein J (SIJ): A new alcohol intake marker. Alcohol 5(3), 173-179 (2001). (Pubitemid 34143114)
    • (2001) Alcohol , vol.25 , Issue.3 , pp. 173-179
    • Ghosh, P.1    Hale, E.A.2    Lakshman, M.R.3
  • 67
    • 77249131163 scopus 로고    scopus 로고
    • Circulating cytokines as biomarkers of alcohol abuse and alcoholism
    • Achur RN, Freeman WM, Vrana KE. Circulating cytokines as biomarkers of alcohol abuse and alcoholism. J. Neuroimmune Pharmacol. 5(1), 83-91 (2010).
    • (2010) J. Neuroimmune Pharmacol. , vol.5 , Issue.1 , pp. 83-91
    • Achur, R.N.1    Freeman, W.M.2    Vrana, K.E.3
  • 68
    • 50249163076 scopus 로고    scopus 로고
    • Serum TNF-alpha levels in relation to alcohol consumption and common TNF gene polymorphisms
    • Gonzalez-Quintela A, Campos J, Loidi L, Quinteiro C, Perez LF, Gude F. Serum TNF-alpha levels in relation to alcohol consumption and common TNF gene polymorphisms. Alcohol 42(6), 513-518 (2008).
    • (2008) Alcohol , vol.42 , Issue.6 , pp. 513-518
    • Gonzalez-Quintela, A.1    Campos, J.2    Loidi, L.3    Quinteiro, C.4    Perez, L.F.5    Gude, F.6
  • 69
    • 35748976584 scopus 로고    scopus 로고
    • Production of inflammatory cytokines by peripheral blood monocytes in chronic alcoholism: Relationship with ethanol intake and liver disease
    • DOI 10.1002/cyto.b.20169
    • Laso FJ, Vaquero JM, Almeida J, Marcos M, Orfao A. Production of inflammatory cytokines by peripheral blood monocytes in chronic alcoholism: Relationship with ethanol intake and liver disease. Cytometry B. Clin. Cytom. 72(5), 408-415 (2007). (Pubitemid 350194358)
    • (2007) Cytometry Part B - Clinical Cytometry , vol.72 , Issue.5 , pp. 408-415
    • Laso, F.J.1    Vaquero, J.M.2    Almeida, J.3    Marcos, M.4    Orfao, A.5
  • 70
    • 10744222980 scopus 로고    scopus 로고
    • Combining carbohydrate-deficient transferrin and gamma- glutamyltransferase to increase diagnostic accuracy for problem drinking
    • World Health Organization
    • Chen J, Conigrave KM, Macaskill P, Whitfield JB, Irwig L; World Health Organization and the International Society for Biomedical Research on Alcoholism Collaborative Group. Combining carbohydrate-deficient transferrin and gamma-glutamyltransferase to increase diagnostic accuracy for problem drinking. Alcohol Alcohol. 38(6), 574-582 (2003).
    • (2003) Alcohol Alcohol. , vol.38 , Issue.6 , pp. 574-582
    • Chen, J.1    Conigrave, K.M.2    Macaskill, P.3    Whitfield, J.B.4    Irwig, L.5
  • 71
    • 0035063271 scopus 로고    scopus 로고
    • Improved diagnostic classification of alcohol abusers by combining carbohydrate-deficient transferrin and -glutamyltransferase
    • Sillanaukee P, Olsson U. Improved diagnostic classification of alcohol abusers by combining carbohydrate-deficient transferrin and gamma- glutamyltransferase. Clin. Chem. 47(4), 681-685 (2001). (Pubitemid 32275811)
    • (2001) Clinical Chemistry , vol.47 , Issue.4 , pp. 681-685
    • Sillanaukee, P.1    Olsson, U.2
  • 72
    • 0036667836 scopus 로고    scopus 로고
    • Carbohydrate-deficient transferrin and -glutamyltransferase for the detection and monitoring of alcohol use: Results from a multisite study
    • Anton RF, Lieber C, Tabakoff B; CDTect Study Group. Carbohydrate- deficient transferrin and gamma-glutamyltransferase for the detection and monitoring of alcohol use: Results from a multisite study. Alcohol. Clin. Exp. Res. 26(8), 1215-1222 (2002). (Pubitemid 34913207)
    • (2002) Alcoholism: Clinical and Experimental Research , vol.26 , Issue.8 , pp. 1215-1222
    • Anton, R.F.1    Lieber, C.2    Tabakoff, B.3
  • 73
    • 34247154303 scopus 로고    scopus 로고
    • Combinations of carbohydrate-deficient transferrin, mean corpuscular erythrocyte volume, gamma-glutamyltransferase, homocysteine and folate increase the significance of biological markers in alcohol dependent patients
    • DOI 10.1016/j.drugalcdep.2006.11.022, PII S0376871606004650
    • Rinck D, Frieling H, Freitag A et al. Combinations of carbohydrate-deficient transferrin, mean corpuscular erythrocyte volume, gamma-glutamyltransferase, homocysteine and folate increase the significance of biological markers in alcohol dependent patients. Drug Alcohol Depend. 89(1), 60-65 (2007). (Pubitemid 46602876)
    • (2007) Drug and Alcohol Dependence , vol.89 , Issue.1 , pp. 60-65
    • Rinck, D.1    Frieling, H.2    Freitag, A.3    Hillemacher, T.4    Bayerlein, K.5    Kornhuber, J.6    Bleich, S.7
  • 74
    • 82955203410 scopus 로고    scopus 로고
    • Comprehensive chromatographic separations in proteomics
    • Donato P, Cacciola F, Mondello L, Dugo P. Comprehensive chromatographic separations in proteomics. J. Chromatogr. A 1218(49), 8777-8790 (2011).
    • (2011) J. Chromatogr. A , vol.1218 , Issue.49 , pp. 8777-8790
    • Donato, P.1    Cacciola, F.2    Mondello, L.3    Dugo, P.4
  • 76
    • 0021274194 scopus 로고
    • Effects of alcohol abuse on human serum proteins revealed by two-dimensional electrophoresis
    • Marshall T, Vesterberg O, Williams K. Effects of alcohol abuse on human serum proteins revealed by two-dimensional electrophoresis. Electrophoresis 5, 122-128 (1984). (Pubitemid 14107028)
    • (1984) Electrophoresis , vol.5 , Issue.2 , pp. 122-128
    • Marshall, T.1    Vesterberg, O.2    Williams, K.M.3
  • 77
    • 0029130646 scopus 로고
    • Two-dimensional protein electrophoresis and multiple hypothesis testing to detect potential serum protein biomarkers in children with fetal alcohol syndrome
    • Robinson MK, Myrick JE, Henderson LO et al. Two-dimensional protein electrophoresis and multiple hypothesis testing to detect potential serum protein biomarkers in children with fetal alcohol syndrome. Electrophoresis 16(7), 1176-1183 (1995).
    • (1995) Electrophoresis , vol.16 , Issue.7 , pp. 1176-1183
    • Robinson, M.K.1    Myrick, J.E.2    Henderson, L.O.3
  • 78
    • 0034923505 scopus 로고    scopus 로고
    • Analysis of proteins and proteomes by mass spectrometry
    • DOI 10.1146/annurev.biochem.70.1.437
    • Mann M, Hendrickson RC, Pandey A. Analysis of proteins and proteomes by mass spectrometry. Annu. Rev. Biochem. 70, 437-473 (2001). (Pubitemid 32662217)
    • (2001) Annual Review of Biochemistry , vol.70 , pp. 437-473
    • Mann, M.1    Hendrickson, R.C.2    Pandey, A.3
  • 80
    • 45349093858 scopus 로고    scopus 로고
    • Proteomic approaches for studying alcoholism and alcohol-induced organ damage
    • Hiller-Sturmhöfel S, Sobin J, Mayfield RD. Proteomic approaches for studying alcoholism and alcohol-induced organ damage. Alcohol. Res. Health 31(1), 36-48 (2008).
    • (2008) Alcohol. Res. Health , vol.31 , Issue.1 , pp. 36-48
    • Hiller-Sturmhöfel, S.1    Sobin, J.2    Mayfield, R.D.3
  • 82
    • 0038063029 scopus 로고    scopus 로고
    • Proteome analysis by two-dimensional gel electrophoresis and mass spectrometry: Strengths and limitations
    • DOI 10.1016/S0165-9936(03)00508-9
    • Beranova-Giorgianni S. Proteome analysis by two-dimensional gel electrophoresis and mass spectrometry: Strengths and limitations. Trends. Analyt. Chem. 22(5), 273-281 (2003). (Pubitemid 36555941)
    • (2003) TrAC - Trends in Analytical Chemistry , vol.22 , Issue.5 , pp. 273-281
    • Beranova-Giorgianni, S.1
  • 83
    • 82955219743 scopus 로고    scopus 로고
    • Separation science is the key to successful biopharmaceuticals
    • Guiochon G, Beaver LA. Separation science is the key to successful biopharmaceuticals. J. Chromatogr. A 1218(49), 8836-8858 (2011).
    • (2011) J. Chromatogr. A , vol.1218 , Issue.49 , pp. 8836-8858
    • Guiochon, G.1    Beaver, L.A.2
  • 84
    • 0035106351 scopus 로고    scopus 로고
    • Large-scale analysis of the yeast proteome by multidimensional protein identification technology
    • DOI 10.1038/85686
    • Washburn MP, Wolters D, Yates JR 3rd. Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat. Biotechnol. 19(3), 242-247 (2001). (Pubitemid 32220565)
    • (2001) Nature Biotechnology , vol.19 , Issue.3 , pp. 242-247
    • Washburn, M.P.1    Wolters, D.2    Yates, J.R.3
  • 85
    • 79951522491 scopus 로고    scopus 로고
    • Proteomic investigation of epigenetics in neuropsychiatric disorders: A missing link between genetics and behavior?
    • Plazas-Mayorca MD, Vrana KE. Proteomic investigation of epigenetics in neuropsychiatric disorders: A missing link between genetics and behavior? J. Proteome Res. 10(1), 58-65 (2011).
    • (2011) J. Proteome Res. , vol.10 , Issue.1 , pp. 58-65
    • Plazas-Mayorca, M.D.1    Vrana, K.E.2
  • 86
    • 4444335470 scopus 로고    scopus 로고
    • The ABC's (and XYZ's) of peptide sequencing
    • DOI 10.1038/nrm1468
    • Steen H, Mann M. The ABC's (and XYZ's) of peptide sequencing. Nat. Rev. Mol. Cell Biol. 5(9), 699-711 (2004). (Pubitemid 39208180)
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , Issue.9 , pp. 699-711
    • Steen, H.1    Mann, M.2
  • 87
    • 77952314463 scopus 로고    scopus 로고
    • Microbial fingerprinting using matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) applications and challenges
    • Giebel R, Worden C, Rust SM, Kleinheinz GT, Robbins M, Sandrin TR. Microbial fingerprinting using matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) applications and challenges. Adv. Appl. Microbiol. 71, 149-184 (2010).
    • (2010) Adv. Appl. Microbiol. , vol.71 , pp. 149-184
    • Giebel, R.1    Worden, C.2    Rust, S.M.3    Kleinheinz, G.T.4    Robbins, M.5    Sandrin, T.R.6
  • 88
    • 11144353824 scopus 로고    scopus 로고
    • Identification of novel and downregulated biomarkers for alcoholism by surface enhanced laser desorption/ionization-mass spectrometry
    • DOI 10.1002/pmic.200300674
    • Nomura F, Tomonaga T, Sogawa K et al. Identification of novel and downregulated biomarkers for alcoholism by surface enhanced laser desorption/ionization-mass spectrometry. Proteomics 4(4), 1187-1194 (2004). (Pubitemid 38445975)
    • (2004) Proteomics , vol.4 , Issue.4 , pp. 1187-1194
    • Nomura, F.1    Tomonaga, T.2    Sogawa, K.3    Ohashi, T.4    Nezu, M.5    Sunaga, M.6    Kondo, N.7    Iyo, M.8    Shimada, H.9    Ochiai, T.10
  • 89
    • 33646180812 scopus 로고    scopus 로고
    • Apo-AII is an elevated biomarker of chronic non-human primate ethanol self-administration
    • Freeman WM, Gooch RS, Lull ME et al. Apo-AII is an elevated biomarker of chronic non-human primate ethanol self-administration. Alcohol Alcohol. 41(3), 300-305 (2006).
    • (2006) Alcohol Alcohol , vol.41 , Issue.3 , pp. 300-305
    • Freeman, W.M.1    Gooch, R.S.2    Lull, M.E.3
  • 90
    • 33846934658 scopus 로고    scopus 로고
    • Opportunities and limitations of SELDI-TOF-MS in biomedical research: Practical advices
    • DOI 10.1586/14789450.4.1.51
    • Poon TC. Opportunities and limitations of SELDI-TOF-MS in biomedical research: practical advices. Expert Rev. Proteomics 4(1), 51-65 (2007). (Pubitemid 46239472)
    • (2007) Expert Review of Proteomics , vol.4 , Issue.1 , pp. 51-65
    • Poon, T.C.W.1
  • 91
    • 79952163192 scopus 로고    scopus 로고
    • Comparison of MALDI-TOF-MS and HPLC-ESI-MS/MS for endopeptidase activity-based quantification of anthrax lethal factor in serum
    • Kuklenyik Z, Boyer AE, Lins R et al. Comparison of MALDI-TOF-MS and HPLC-ESI-MS/MS for endopeptidase activity-based quantification of anthrax lethal factor in serum. Anal. Chem. 83(5), 1760-1765 (2011).
    • (2011) Anal. Chem. , vol.83 , Issue.5 , pp. 1760-1765
    • Kuklenyik, Z.1    Boyer, A.E.2    Lins, R.3
  • 92
    • 66849089268 scopus 로고    scopus 로고
    • Protein microarrays: High-throughput tools for proteomics
    • Stoevesandt O, Taussig MJ, He M. Protein microarrays: high-throughput tools for proteomics. Expert Rev. Proteomics 6(2), 145-157 (2009).
    • (2009) Expert Rev. Proteomics , vol.6 , Issue.2 , pp. 145-157
    • Stoevesandt, O.1    Taussig, M.J.2    He, M.3
  • 93
    • 33645463194 scopus 로고    scopus 로고
    • Multiplexed protein measurement: Technologies and applications of protein and antibody arrays
    • Kingsmore SF. Multiplexed protein measurement: Technologies and applications of protein and antibody arrays. Nat. Rev. Drug Discov. 5(4), 310-320 (2006).
    • (2006) Nat. Rev. Drug Discov. , vol.5 , Issue.4 , pp. 310-320
    • Kingsmore, S.F.1
  • 94
    • 33846305075 scopus 로고    scopus 로고
    • Diagnostic values of surface-enhanced laser desorption/ionization technology for screening of habitual drinkers
    • Sogawa K, Itoga S, Tomonaga T, Nomura F. Diagnostic values of surface-enhanced laser desorption/ionization technology for screening of habitual drinkers. Alcohol. Clin. Exp. Res. 31(Suppl. 1), S22-S26 (2007).
    • (2007) Alcohol. Clin. Exp. Res. , vol.31 , Issue.SUPPL. 1
    • Sogawa, K.1    Itoga, S.2    Tomonaga, T.3    Nomura, F.4
  • 95
    • 70350089209 scopus 로고    scopus 로고
    • A search for novel markers of alcohol abuse using magnetic beads and MALDI-TOF/TOF mass spectrometry
    • Sogawa K, Satoh M, Kodera Y, Tomonaga T, Iyo M, Nomura F. A search for novel markers of alcohol abuse using magnetic beads and MALDI-TOF/TOF mass spectrometry. Proteomics. Clin. Appl. 3(7), 821-828 (2009).
    • (2009) Proteomics. Clin. Appl. , vol.3 , Issue.7 , pp. 821-828
    • Sogawa, K.1    Satoh, M.2    Kodera, Y.3    Tomonaga, T.4    Iyo, M.5    Nomura, F.6
  • 96
    • 78851469730 scopus 로고    scopus 로고
    • Increased serum levels of pigment epithelium-derived factor by excessive alcohol consumption-detection and identification by a three-step serum proteome analysis
    • Sogawa K, Kodera Y, Satoh M et al. Increased serum levels of pigment epithelium-derived factor by excessive alcohol consumption-detection and identification by a three-step serum proteome analysis. Alcohol. Clin. Exp. Res. 35(2), 211-217 (2011).
    • (2011) Alcohol. Clin. Exp. Res. , vol.35 , Issue.2 , pp. 211-217
    • Sogawa, K.1    Kodera, Y.2    Satoh, M.3
  • 97
    • 69449104538 scopus 로고    scopus 로고
    • A proteomic workflow for discovery of serum carrier protein-bound biomarker candidates of alcohol abuse using LC-MS/MS
    • Lai X, Liangpunsakul S, Crabb DW, Ringham HN, Witzmann FA. A proteomic workflow for discovery of serum carrier protein-bound biomarker candidates of alcohol abuse using LC-MS/MS. Electrophoresis 30(12), 2207-2214 (2009).
    • (2009) Electrophoresis , vol.30 , Issue.12 , pp. 2207-2214
    • Lai, X.1    Liangpunsakul, S.2    Crabb, D.W.3    Ringham, H.N.4    Witzmann, F.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.