Biomarkers for alcohol use and abuse: A summary

Alcohol Research and Health

Volumn 28, Issue 1, 2004, Pages 30-37

  Peterson, Karen ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

Alcohol related biochemical markers; Alcohol related biological markers; Alcohol related genetic markers; Pattern of AOD use; Screening and diagnostic method for AOD (alcohol and other drug) use

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; GAMMA GLUTAMYLTRANSFERASE; N ACETYLNEURAMINIC ACID;

ALCOHOLISM; BLOOD; HUMAN; REVIEW;

ALANINE TRANSAMINASE; ALCOHOLISM; ASPARTATE AMINOTRANSFERASES; BIOLOGICAL MARKERS; GAMMA-GLUTAMYLTRANSFERASE; HUMANS; N-ACETYLNEURAMINIC ACID;

EID: 27744530929     PISSN: 0090838X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (30)

1. ANTTILA, P.; JARVI, K.; LATVALA, J.; AND NIEMELA, O. Method-dependent characteristics of carbohydrate-deficient transferrin measurements in the follow-up of alcoholics. Alcohol and Alcoholism 39(1): 59-63, 2004.
2. ARNDT, T. Carbohydrate-deficient transferrin as a marker of chronic alcohol abuse: A critical review of preanalysis, analysis, and interpretation. Clinical Chemistry 47(1):13-27, 2000.
3. BALLDIN, J.; ALLING, C.; GOTTFRIES, C.G.; ET AL. Changes in dopamine receptor sensitivity in humans after heavy alcohol intake. Psychopharmacology 86:142-146, 1985.
4. BEAN, P.; HARASYMIW, J.; PETERSON, C.M.; AND JAVORS, M. Innovative technologies for the diagnosis of alcohol abuse and monitoring abstinence. Alcoholism: Clinical and Experimental Research 25(2):309-316, 2001.
5. BECK, O., AND HELANDER, A. 5-hydroxytryptophol as a marker for recent alcohol intake. Addiction 98(Suppl. 2):63-72, 2003.
6. CHEN, J.; CONIGRAVE, K.M.; MACASKILL, P.; ET AL. on behalf of the World Health Organization and the International Society for Biomedical Research on Alcoholism Collaborative Group. Combining carbohydrate-deficient transferrin and gamma-glutamyltransferase to increase diagnostic accuracy for problem drinking. Alcohol and Alcoholism 38(6):574-582, 2003.
7. CONIGRAVE, K.M.; DAVIES, P.; HABER, P.; AND WHITFIELD, J.B. Traditional markers of excessive alcohol use. Addiction 98(Suppl. 2):31-43, 2003.
8. GEORGE, D.T.; RAWLINGS, R.R.; ECKARDT, M.J.; ET AL. Buspirone treatment of alcoholism: Age of onset, and cerebrospinal fluid 5-hydroxyindolacetic acid and homovanillic acid concentrations, but not medication treatment, predict return to drinking. Alcoholism: Clinical and Experimental Research 23(2):272-278, 1999.
9. HABER, H.; JAHN, H.; EHRENREICH, H.; AND MELZIG, M.F. Assay of salsolinol in peripheral blood mononuclear cells of alcoholics and healthy subjects by gas chromatography-mass spectrometry. Addiction Biology 7(4):403-407, 2002.
10. HALVORSON, M.R.; CAMPBELL, J.L.; SPRAGUE, G.; ET AL. Comparative evaluation of the clinical utility of three markers of ethanol intake: The effect of gender. Alcoholism: Clinical and Experimental Research 17(2):225-229, 1993.
11. HOFFMAN, P.L.; GLANZ, J.; TABAKOFF, B.; and the WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence Investigators. Platelet adenylyl cyclase activity as a state or trait marker in alcohol dependence: Results of the WHO/ISBRA study on state and trait markers of alcohol use and dependence. Alcoholism: Clinical and Experimental Research 26(7):1078-1087, 2002.
12. JAVORS, M.A., AND JOHNSON, B.A. Current status of carbohydrate-deficient transferrin, total serum sialic acid, sialic acid index of apolipoprotein J and serum beta-hexosaminidase as markers for alcohol consumption. Addiction 98(Suppl. 2):45-50, 2003.
13. JOHNSON, R.D.; LEWIS, R.J.; CANFIELD, D.V.; AND BLANK, C. L. Accurate assignment of ethanol origin in postmortem urine: Liquid chromatographic-mass spectrometric determination of serotonin metabolites. Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences 805(2):223-234, 2004.
14. MIHIC, S.J., AND HARRIS, R.A. Alcohol actions at the GABA-A receptor/chloride channel complex. In: Deitrich, R.A., and Erwin, V.G., eds. Pharmacological Effects of Ethanol on the Nervous System. Boca Raton: CRC Press, 1996. pp. 51-72.
15. MUSSHOFF, F.; LACHENMEIER, D.W.; SCHMIDT, P.; ET AL. Systematic regional study of dopamine, nor-salsolinol, and (R/S)-salsolinol levels in human brain areas of alcoholics. Alcoholism: Clinical and Experimental Research 29(1):46-52, 2005.
16. NEUMANN, T., AND SPIES, C. Use of biomarkers for alcohol use disorders in clinical practice. Addiction 98(Suppl. 2):81-91, 2003.
17. NOMURA, F.; TOMONAGA, T.; SOGAWA, K.; ET AL. Identification of novel and downregulated biomarkers for alcoholism by surface-enhanced laser desorption/ionization-mass spectrometry. Proteomics 4(4):1187-1194, 2004.
18. OROSZI, G., AND GOLDMAN, D. Alcoholism: Genes and mechanisms. Pharmacogenomics 5(8): 1037-1048, 2004.
19. OSWALD, L.M., AND WAND, G.S. Opioids and alcoholism. Physiological Behavior 81(2):339-358, 2004.
20. PETERSON, C.M., AND POLIZZI, C.M. Improved method for acetaldehyde in plasma and hemoglobin-associated acetaldehyde: Results in teetotalers and alcoholics reporting for treatment. Alcohol 4(6):477-480, 1987.
21. PETRAKIS, I.L.; TREVISAN, L.; D'SOUZA, C.; ET AL. CSF monoamine metabolite and beta endorphin levels in recently detoxified alcoholics and healthy controls: Prediction of alcohol cue-induced craving. Alcoholism: Clinical and Experimental Research 23(8):1336-1341, 1999.
22. RATSMA, J.E.; VAN DER STELT, O.; AND GUNNING, W.B. Neurochemical markers of alcoholism vulnerability in humans. Alcohol and Alcoholism 37(6): 522-533, 2002.
23. SALEM, R.O.; REFAAI, M.A.; CLUETT-BROWN, J.E.; ET AL. Fatty acid ethyl esters in liver and adipose tissues as postmortem markers for ethanol intake. Clinical Chemistry 47(4):722-725, 2001.
24. STOWELL, L.; STOWELL, A.; GARRETT, N.; AND ROBINSON, G. Comparison of serum beta-hexosaminidase isoenzyme B activity with serum carbohydrate-deficient transferrin and other markers of alcohol abuse. Alcohol and Alcoholism 32(6):702-714, 1997.
25. SWANN, A.C.; JOHNSON, B.A.; CLONINGER, C.R.; AND CHEN, Y.R. Relationships of plasma tryptophan availability to course of illness and clinical features of alcoholism: A preliminary study. Psychopharmacology 143(4):380-384, 1999.
26. VOLPICELLI, J.; O'BRIEN, C.; ALTERMAN, A.; AND HAYSHIDA, M. Naltrexone in the treatment of alcohol dependence: Initial observations. In: Reid, L.D., ed. Opioids, Bulimia, and Alcohol Abuse and Alcoholism. New York: Springer-Verlag, 1990. pp. 195-214.
27. WURST, F.M.; SKIPPER, G.E.; AND WEINMANN, W. Ethyl glucuronide - The direct ethanol metabolite on the threshold from science to routine use. Addiction 98(Suppl. 2):51-61, 2003.
28. WURST, F.M.; ALEXSON, S.; WOLFERSDORF, M.; ET AL. Concentration of fatty acid ethyl esters in hair of alcoholics: Comparison to other biological state markers and self-reported ethanol intake. Alcohol and Alcoholism 39(1):33-38, 2004.
29. YEGLES, M.; LABARTHE, A.; AUWARTER, V.; ET AL. Comparison of ethyl glucuronide and fatty acid ethyl ester concentrations in hair of alcoholics, social drinkers and teetotalers. Forensic Science International 145(2/3):167-173, 2004.
30. ZALEWSKA-KASZUBSKA, J., AND CZARNECKA, E. Deficit in beta-endorphin peptide and tendency to alcohol abuse. Peptides 26(4):701-705, 2005.