Analysis of carbohydrate deficient transferrin serum levels during abstinence

Experimental and Molecular Pathology

Volumn 92, Issue 1, 2012, Pages 50-53

  Ridinger, Monika ^a   Köhl, Philiph ^a   Gäbele, Erwin ^a   Wodarz, Norbert ^a   Schmitz, Gerd ^a   Kiefer, Paul ^a   Hellerbrand, Claus ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Alcoholism; Biomarker; CDT

Indexed keywords

CARBOHYDRATE DEFICIENT TRANSFERRIN; GAMMA GLUTAMYLTRANSFERASE;

ADULT; ALCOHOL ABSTINENCE; ALCOHOL ABUSE; ALCOHOL BLOOD LEVEL; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRINKING BEHAVIOR; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HUMAN; IMMUNODETECTION; ION EXCHANGE; MALE; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL;

ADULT; ALCOHOL DRINKING; ALCOHOLISM; BIOLOGICAL MARKERS; FEMALE; HUMANS; MALE; MIDDLE AGED; TEMPERANCE; TIME FACTORS; TRANSFERRIN;

EID: 80755152933     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2011.10.005     Document Type: Article

References (31)

1. Aalto M., Seppa K. Use of laboratory markers and the audit questionnaire by primary care physicians to detect alcohol abuse by patients. Alcohol Alcohol. 2005, 40:520-523.
2. Allen J.P., Litten R.Z. Recommendations on use of biomarkers in alcoholism treatment trials. Alcohol. Clin. Exp. Res. 2003, 27:1667-1670.
3. Alling C., Chick J.D., Anton R., et al. Revealing alcohol abuse: to ask or to test?. Alcohol. Clin. Exp. Res. 2005, 29:1257-1263.
4. American Psychiatric Association Diagnostisches und Statistisches Manual Psychischer Störungen 1996, DSM-IV, Hogrefe, Göttingen, Bern, Toronto.
5. Anttila P., Jarvi K., Latvala J., Blake J.E., Niemela O. A new modified gamma-%CDT method improves the detection of problem drinking: studies in alcoholics with or without liver disease. Clin. Chim. Acta 2003, 338:45-51.
6. Arndt T., Kropf J. Alcohol abuse and carbohydrate-deficient transferrin analysis: are screening and confirmatory analysis required. Clin. Chem. 2002, 48:2072-2074.
7. DiMartini A., Day N., Lane T., Beisler A.T., Dew M.A., Anton R. Carbohydrate deficient transferrin in abstaining patients with end-stage liver disease. Alcohol. Clin. Exp. Res. 2001, 25:1729-1733.
8. Hartmann S., Aradottir S., Graf M., et al. Phosphatidylethanol as a sensitive and specific biomarker: comparison with gamma-glutamyl transpeptidase, mean corpuscular volume and carbohydrate-deficient transferrin. Addict. Biol. 2007, 12:81-84.
9. Helander A. Absolute or relative measurement of carbohydrate-deficient transferrin in serum? Experiences with three immunological assays. Clin. Chem. 1999, 45:131-135.
10. Helander A., Tabakoff B. Biochemical markers of alcohol use and abuse: experiences from the Pilot Study of the WHO/ISBRA Collaborative Project on state and trait markers of alcohol. International Society for Biomedical Research on Alcoholism. Alcohol Alcohol. 1997, 32:133-144.
11. Helander A., Eriksson G., Stibler H., Jeppsson J.O. Interference of transferrin isoform types with carbohydrate-deficient transferrin quantification in the identification of alcohol abuse. Clin. Chem. 2001, 47:1225-1233.
12. Hietala J., Koivisto H., Anttila P., Niemela O. Comparison of the combined marker GGT-CDT and the conventional laboratory markers of alcohol abuse in heavy drinkers, moderate drinkers and abstainers. Alcohol Alcohol. 2006, 41:528-533.
13. Huseby N.E., Nilssen O., Erfurth A., Wetterling T., Kanitz R.D. Carbohydrate-deficient transferrin and alcohol dependency: variation in response to alcohol intake among different groups of patients. Alcohol. Clin. Exp. Res. 1997, 21:201-205.
14. Kwoh-Gain I., Fletcher L.M., Price J., Powell L.W., Halliday J.W. Desialylated transferrin and mitochondrial aspartate aminotransferase compared as laboratory markers of excessive alcohol consumption. Clin. Chem. 1990, 36:841-845.
15. Lachner G., Wittchen H.U., Perkonigg A., et al. Structure, content and reliability of the Munich-Composite International Diagnostic Interview (M-CIDI) substance use sections. Eur. Addict. Res. 1998, 4:28-41.
16. Lesch O.M., Walter H., Antal J., et al. Carbohydrate-deficient transferrin as a marker of alcohol intake: a study with healthy subjects. Alcohol Alcohol. 1996, 31:265-271.
17. Lieber C.S. Medical disorders of alcoholism. N. Engl. J. Med. 1995, 19(333):1058-1065.
18. Miller W.R. Form 90. A structured assessment interview for drinking and related behaviors. Test Manual. NIAAA Project MATCH Monograph Series, Vol.5.US. NIH Pub.NO.96-4004 1996, U.S. Government Printing Office, Washington, DC.
19. Mundle G., Munkes J., Ackermann K., Mann K. Sex differences of carbohydrate-deficient transferrin, gamma-glutamyltransferase, and mean corpuscular volume in alcohol-dependent patients. Alcohol. Clin. Exp. Res. 2000, 24:1400-1405.
20. Niemela O. Biomarkers in alcoholism. Clin. Chim. Acta 2007, 377:39-49.
21. Niemela O., Sorvajarvi K., Blake J.E., Israel Y. Carbohydrate-deficient transferrin as a marker of alcohol abuse: relationship to alcohol consumption, severity of liver disease, and fibrogenesis. Alcohol. Clin. Exp. Res. 1995, 19:1203-1208.
22. Salmela K.S., Laitinen K., Nystrom M., Salaspuro M. Carbohydrate-deficient transferrin during 3 weeks' heavy alcohol consumption. Alcohol. Clin. Exp. Res. 1994, 18:228-230.
23. Schellenberg F., Schwan R., Mennetrey L., Loiseaux M.N., Pages J.C., Reynaud M. Dose-effect relation between daily ethanol intake in the range 0-70grams and %CDT value: validation of a cut-off value. Alcohol Alcohol. 2005, 40:531-534.
24. Scheurich A. MTDMMJTBWHDMHM&SA. Form 90: Strukturierte Interviews zur Erhebung der aktuellen Trinkmenge und des aktuellen Trinkverhaltens (Brief Form 90). Elektonisches Handbuch zu Erhebungsinstrumenten im Suchtbereich (EHES), Version 2.00 2002, Zentren f.Umfragen, Methoden und Analysen, Mannheim. A. Glöckner-Rist, F. Rist, H. Kufner (Eds.).
25. Sillanaukee P., Olsson U. Improved diagnostic classification of alcohol abusers by combining carbohydrate-deficient transferrin and gamma-glutamyltransferase. Clin. Chem. 2001, 47:681-685.
26. Sillanaukee P., Massot N., Jousilahti P., et al. Dose response of laboratory markers to alcohol consumption in a general population. Am. J. Epidemiol. 2000, 152:747-751.
27. Stibler H. Carbohydrate-deficient transferrin in serum: a new marker of potentially harmful alcohol consumption reviewed. Clin. Chem. 1991, 37:2029-2037.
28. Storey E.L., Anderson G.J., Mack U., Powell L.W., Halliday J.W. Desialylated transferrin as a serological marker of chronic excessive alcohol ingestion. Lancet 1987, 1:1292-1294.
29. Wittchen H.U. Reliability and validity studies of the WHO-Composite International Diagnostic Interview (CIDI): a critical review. J. Psychiatr. Res. 1994, 28:57-84.
30. World Health Organization The ICD-10 Classification of Mental and Behavioural disorders 1992, Clinical Descriptions and Diagnostic Guidelines, Genf.
31. Wurst F.M., Alling C., Aradottir S., et al. Emerging biomarkers: new directions and clinical applications. Alcohol. Clin. Exp. Res. 2005, 29:465-473.