Thermodynamic and kinetic analysis of peptides derived from CapZ, NDR, p53, HDM2, and HDM4 binding to human S100B

Biochemistry

Volumn 51, Issue 36, 2012, Pages 7189-7201

  Wafer, Lucas N ^a   Streicher, Werner W ^a,b   McCallum, Scott A ^a   Makhatadze, George I ^a  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER'S DISEASE; BINDING AFFINITIES; CONFORMATIONAL CHANGE; DISSOCIATION CONSTANT; EF-HAND; EXTRACELLULAR; HYDROPHOBIC BINDING; ISOTHERMAL TITRATION CALORIMETRY; KINETIC BINDING; LINE SHAPE; MALIGNANT MELANOMA; NANOMOLAR RANGE; NEURODEGENERATIVE; PARKINSON'S DISEASE; TARGET PROTEINS; THERMODYNAMIC AND KINETIC ANALYSIS;

BINDING ENERGY; DISSOCIATION; KINETICS; NEURODEGENERATIVE DISEASES; RATE CONSTANTS;

PEPTIDES;

HDM4 PROTEIN; LIGASE; NUCLEAR DBF2 RELATED KINASE; PHOSPHOTRANSFERASE; PROTEIN CAPZ; PROTEIN MDM2; PROTEIN P53; PROTEIN S100B; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BINDING AFFINITY; ENZYME BINDING; HUMAN; ISOTHERMAL TITRATION CALORIMETRY; KINETICS; MOLECULAR RECOGNITION; NITROGEN NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTON NUCLEAR MAGNETIC RESONANCE; THERMODYNAMICS;

AMINO ACID SEQUENCE; CAPZ ACTIN CAPPING PROTEIN; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NERVE GROWTH FACTORS; NUCLEAR PROTEINS; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; S100 PROTEINS; THERMODYNAMICS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84866110486     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300865g     Document Type: Article

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