Structure of the Ca2+/S100B/NDR Kinase Peptide Complex: Insights into S100 Target Specificity and Activation of the Kinase

Biochemistry

Volumn 42, Issue 49, 2003, Pages 14416-14426

  Bhattacharya, Shibani ^a   Large, Edward ^a   Heizmann, Claus W ^b   Hemmings, Brian ^c   Chazin, Walter J ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; COMPLEXATION; CONFORMATIONS; ELECTROSTATICS; ENZYMES; HYDROPHOBICITY; MOLECULAR STRUCTURE; STOICHIOMETRY;

AUTOINHIBITION; PHOSPHORYLATION;

BIOCHEMISTRY;

CALCIUM; CALMODULIN; CALMODULIN DEPENDENT KINASE; DBF2 KINASE; DIMER; NUCLEAR DBF2 RELATED KINASE; PEPTIDE DERIVATIVE; PHOSPHOTRANSFERASE; PROTEIN S 100; PROTEIN S100B; PROTEIN SERINE THREONINE KINASE; PROTEIN SUBUNIT; REGULATOR PROTEIN; SERINE; THREONINE; UNCLASSIFIED DRUG; BRD2 PROTEIN, HUMAN; NERVE GROWTH FACTOR; PEPTIDE FRAGMENT; S 100 CALCIUM BINDING PROTEIN BETA SUBUNIT; S-100 CALCIUM-BINDING PROTEIN BETA SUBUNIT;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING ASSAY; CARBOXY TERMINAL SEQUENCE; CELL PROLIFERATION; CELL STRUCTURE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; ELECTRIC POTENTIAL; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBUNIT; HUMAN; MOLECULAR INTERACTION; MOLECULAR MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; STOICHIOMETRY; STRUCTURE ANALYSIS; ANIMAL; CATTLE; CHEMISTRY; COMPARATIVE STUDY; DIMERIZATION; HYDROPHOBICITY; MACROMOLECULE; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; SEQUENCE ALIGNMENT; STRUCTURAL HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CATTLE; DIMERIZATION; HUMANS; HYDROPHOBICITY; MACROMOLECULAR SUBSTANCES; MOLECULAR SEQUENCE DATA; NERVE GROWTH FACTORS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN-SERINE-THREONINE KINASES; S100 PROTEINS; SEQUENCE ALIGNMENT; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 0347481143     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035089a     Document Type: Article

References (82)

1. Zimmer, D. B., Cornwall, E. H., Landar, A., and Song, W. (1995) Brain Res. Bull. 37, 417-429.
2. Heizmann, C. W., and Cox, J. A. (1998) Biometals 11, 383-97.
3. Donato, R. (2001) Int. J. Biochem. Cell Biol. 33, 637-668.
4. Heizmann, C. W., Fritz, G., and Schäfer, B. W. (2002) Frontiers Biosci. 7, 1356-1368.
5. Mrak, R. E., Sheng, J. G., and Griffin, W. S. (1995) Hum. Pathol. 26, 816-823.
6. Castets, F., Griffin, W. S., Marks, A., and Van Eldik, L. J. (1997) Brain Res. Mol. Brain Res. 46, 208-16.
7. Heizmann, C. W. (1999) Neurochem. Res. 24, 1097-100.
8. Ikura, M., Osawa, M., and Ames, J. B. (2002) Bioessays 24, 625-636.
9. Huttunen, H. J., Kuja-Panula, J., Sorci, G., Agneletti, A. L., Donato, R., and Rauvala, H. (2000) J. Biol. Chem. 275, 40096-40105.
10. Schmidt, A. M., Yan, S. D., Yan, S. F., and Stern, D. M. (2001) J. Clin. Invest. 708, 949-955.
11. Bucciarelli, L. G., Wendt, T., Rong, L., Lalla, E., Hofmann, M. A., Goova, M. T., Taguchi, A., Yan, S. F., Yan, S. D., and Stem, D. M. (2002) Cell. Mol. Life Sci. 59, 1117-1128.
12. Millward, T., Cron, P., and Hemmings, B. A. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 5022-6.
13. Millward, T. A., Heizmann, C. W., Schäfer, B. W., and Hemmings, B. A. (1998) EMBO J. 17, 5913-22.
14. Selinfreund, R. H., Barger, S. W., Welsh, M. J., and Van Eldik, L. J. (1990) J. Cell Biol. 111, 2021-2028.
15. Geng, W., He, B., Wang, M., and Adler, P. N. (2000) Genetics 156, 1817-28.
16. Zallen, J. A., Peckol, E. L., Tobin, D. M., and Bargmann, C. I. (2000) Mol. Biol. Cell 11, 3177-90.
17. Verde. F., Wiley, D. J., and Nurse, P. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 7526-7531.
18. Bidlingmaier, S., Weiss, E. L., Seidel, C., Drubin, D. G., and Snyder, M. (2001) Mol. Cell. Biol. 21, 2449-62.
19. Hanks, S. K., and Hunter, T. (1995) FASEB J. 9, 576-596.
20. Millward, T. A., Hess, D., and Hemmings, B. A. (1999) J. Biol. Chem. 274, 33847-50.
21. Tamaskovic, R., Bichsel, S. J., Rogniaux, H., Stegert, M. R., and Hemmings, B. A. (2003) J. Biol. Chem. 278, 6710-6718.
22. Wilmann, M., Gautel, M., and Mayans, O. (2000) Cell. Mol. Biol. 46, 883-894.
23. Fritz, G., and Heizmann, C. W. (2003) 3D-Structures of the calciam and zinc binding S100 proteins, Vol. 3, John Wiley & Sons, Chichester, New York, Weinheim, Brisbane, Singapore, Toronto.
24. Drohat, A. C., Amburgey, J. C., Abildgaard, F., Starich, M. R., Baldisseri, D., and Weber, D. J. (1996) Biochemistry 35, 11577-88.
25. Kilby, P. M., Van Eldik, L. J., and Roberts, G. C. (1996) Structure 4, 1041-52.
26. Drohat, A. C., Baldisseri, D. M., Rustandi, R. R., and Weber, D. J. (1998) Biochemistry 37, 2729-40.
27. Matsumura, H., Shiba, T., Inoue, T., Harada, S., and Kai, Y. (1998) Structure 6, 233-41.
28. Smith, S. P., and Shaw, G. S. (1998) Structure 6, 211-22.
29. Rety, S., Osterloh, D., Arie, J. P., Tabaries, S., Seeman, J., Russo-Marie, F., Gerke, V., and Lewit-Bentley, A. (2000) Struct. Fold. Des. 8, 175-84.
30. Van Eldik, L. J., Staecker, J. L., and Winningham-Major, F. (1988) J. Biol. Chem. 263, 7830-7837.
31. Wingfield, P. T., Palmer, I., Liang, S.-M., and Pain, R. H. (2002) in Current Protocols in Protein Science (Coligan, J. E., Dunn, B. M., Speicher, D. W., and Wingfield, P. T., Eds.) John Wiley and Sons, New York.
32. Muhandiram, D. R., and Kay, L. E. (1994) J. Magn. Reson., Ser. B 103, 203-216.
33. Cavanagh, J., Fairbrother, W. J., Palmer, A. G. I., and Skelton, N. J. (1996). Protein NMR spectroscopy: Principles and practice, Academic Press, San Diego.
34. Sattler, M., Schleucher, J., and Greisinger, C. (1999) Prog. NMR Spectrosc. 34, 93-158.
35. Kay, L. E., Xu, G. Y., Singer, A. U., Muhandiram, D. R., and Forman-Kay, J. D. (1993) J. Magn. Reson., B 101, 333-337.
36. Muhandiram, D. R., Farrow, N. A., Xu, G. Y., Smallcombe, S. H., and Kay, L. E. (1993) J. Magn. Reson., B 102, 317-321.
37. Talluri, S., and Wagner, G. (1996) J. Magn. Reson, B 112, 200-205.
38. Mori, S., Abeygunawardana, C., Johnson, M. O., and van Zijli, P. C. (1995) J. Magn. Reson., B 108, 94-98.
39. Rustandi, R. R., Baldisseri, D. M., and Weber, D. J. (2000) Nat. Struct. Biol. 7, 570-4.
40. Inman, K. G., Yang, R., Rustandi, R. R., Miller, K. E., Baldisseri, D. M., and Weber, D. J. (2002) J. Mol. Biol. 24, 1003-1014.
41. McClintock, K. A., and Shaw, G. S. (2002) J. Biol. Chem. 278, 6251-6257.
42. Ikura, M., and Bax, A. (1992) J. Am. Chem. Soc. 114, 2433-2440.
43. Lee, W., Revington, M. J., Arrowsmith, C., and Kay, L. E. (1994) FEBS Lett. 350, 87-90.
44. Vuister, G. W., Kim, S.-J., Wu, C., and Bax, A. (1994) J. Am. Chem. Soc. 116, 9206-9210.
45. Zwahlen, C., Legault, P., Vincent, S. J. F., Greenbalt, J., Konrat, R., and Kay, L. E. (1997) J. Am. Chem. Soc. 119, 6711-6721.
46. Duggan, B. M., Legge, G. B., Dyson, H. J., and Wright, P. E. (2001) J. Biomol. NMR 19, 321-329.
47. Wüthrich, K., Billeter, M., and Braun, M. (1983) J. Mol. Biol. 169, 949-961.
48. Güntert, P., Braun, W., and Wüthrich, K. (1991) J. Mol. Biol. 217, 517-530.
49. Güntert, P., Mumenthaler, C., and Wüthrich, K. (1997) J. Mol. Biol. 273, 283-298.
50. Cornilescu, G., Delaglio, F., and Bax, A. (1999) J. Biomol. NMR 13, 289-302.
51. Weiner, S. J., Kollman, P. A., Nguyen, D. T., and Case, D. A. (1986) J. Comput. Chem. 7, 230-252.
52. Pearlman, D. A., Case, D. A., Caldwell, J. C., Seibel, G. L., Singh, U. C., Weiner, P., and Kollman, P. A. (1991) AMBER, University of California.
53. Macke, T. J. (1996) Ph.D. Thesis, The Scripps Research Institute, La Jolla, CA.
54. Sastry, M., Ketchem, R. R., Crescenzi, O., Weber, C., Lubienski, M. J., Hidaka, H., and Chazin, W. J. (1998) Structure 6, 223-31.
55. Mäler, L., Potts, B. C., and Chazin, W. J. (1999) J. Biomol. NMR 13, 233-47.
56. Smith, J., Paloma, L. G., Case, D. A., and Chazin, W. J. (1996) Magn. Reson. Chem. 34, 147-155.
57. Laskowski, R. A., Rullman, J. A. C., MacArthur, M. W., Kaptein, R., and Thomton, J. M. (1996) J. Biomol. NMR 8, 477-486.
58. Koradi, R., Billeter, M., and Wüthrich, K. (1996) J. Mol. Graphics 14, 51-55.
59. Rety, S., Sopkova, J., Renouard, M., Osterloh, D., Gerke, V., Tabaries, S., Russo-Marie, F., and Lewit-Bentley, A. (1999) Nat. Struct. Biol. 6, 89-95.
60. McClintock, K. A., Van Eldik, L. J., and Shaw, G. S. (2002) Biochemistry 41, 5421-5428.
61. Landar, A., Rustandi, R. R., Weber, D. J., and Zimmer, D. B. (1998) Biochemistry 37, 17429-17438.
62. Garbuglia, M., Verzini, M., Rustandi, R. R., Osterloh, D., Weber, D. J., Gerke, V., and Donato, R. (1999) Biochem. Biophys. Res. Commun. 254, 36-41.
63. Seeman, J., Weber, K., and Gerke, V. (1996) Biochem. J. 319, 123-129.
64. Sopalla, C., Leukert, N., Sorg, C., and Kerkhoff, C. (2002) Biol. Chem. 383, 1895-1905.
65. Christakos, S., Gabrielides, C., and Rhoten, W. B. (1989) Endocr. Rev. 10, 3-26.
66. Ivanenkov, V. V., Jamieson, G. A., Gruenstein, E., and Dimlich, R. V. W. (1995) J. Biol. Chem. 270, 14651-14658.
67. McClintock, K. A., and Shaw, G. S. (2000) Protein Sci. 9, 2043-2046.
68. Brokx, R. D., Lopez, M. M., Vogel, H. J., and Makhatadze, G. I. (2001) J. Biol. Chem. 276, 14083-14091.
69. Rustandi, R. R., Baldisseri, D. M., Drohat, A. C., and Weber, D. J. (1999) Protein Sci. 8, 1743-51.
70. Peersen, O. B., Madsen, T. S., and Falke, J. J. (1997) Protein Sci. 6, 794-807.
71. Rustandi, R. R., Drohat, A. C., Baldisseri, D. M., Wilder, P. T., and Weber, D. J. (1998) Biochemistry 37, 1951-60.
72. Heierhorst, J., Kobe, B., Feil, S. C., Parker, M. W., Benian, G. M., Weiss, K. R., and Kemp, B. E. (1996) Nature 380, 636-9.
73. Heierhorst, J., Mann, R. J., and Kemp, B. E. (1997) Eur. J. Biochem. 249, 127-133.
74. Goldberg, J., Naim, A. C., and Kuriyan, J. (1996) Cell 84, 857-887.
75. Huse, M., and Kuriyan, J. (2002) Cell 109, 275-282.
76. Thompson, J. D., Gibson, T. J., Plewniak, F., Jeanmougin, F., and Higgins, D. J. (1997) Nucleic Acids Res. 24, 4876-4882.
77. Sali, A., and Blundell, T. L. (1993) J. Mol. Biol. 234, 779-815.
78. Knighton, D. R., Zheng, J. H., Ten Eyck, L. F., Xuong, N. H., Taylor, S. S., and Sowadski, J. M. (1991) Science 253, 414-420.
79. Knighton, D. R., Zheng, J. H., Ten Eyck, L. F., Ashford, V. A., Xuong, N. H., Taylor, S. S., and Sowadski, J. M. (1991) Science 253, 407-414.
80. Bossemeyer, D., Engh, R. A., Kinzel, V., Ponstingl, H., and Huber, R. (1993) EMBO J. 12, 849-859.
81. Yang, J., Cron, P., Good, V. M., Thompson, V., Hemmings, B. A., and Barford, D. (2002) Nat. Struct. Biol. 9, 940-944.
82. Wybenga-Groot, L. E., Baskin, B., Ong, S. H., Tong, J., Pawson, T., and Sicheri, F. (2001). Cell 106, 745-757.