Intrinsically disordered p53 extreme C-terminus binds to S100B(ββ) through "fly-casting"

Journal of the American Chemical Society

Volumn 131, Issue 6, 2009, Pages 2088-2089

  Chen, Jianhan ^a  

^a KANSAS STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BINDING ENERGY; DNA SEQUENCES; FREE ENERGY; LAWS AND LEGISLATION; PROTEIN FOLDING;

ATOMISTIC SIMULATIONS; BINDING RATE; C-TERMINUS; CELLULAR REGULATION; COARSE-GRAINED MODELING; DISORDERED PROTEINS; FOLDED STATE; FUNCTIONAL PROTEINS; INITIAL CONTACT; MULTIDIMENSIONAL FREE ENERGY; PHYSICS-BASED; RESIDUAL STRUCTURE; STABLE STRUCTURES; TERTIARY STRUCTURES; THERMODYNAMIC CONTROL; UNBOUND STATE; UNDERLYING MECHANISM;

BINDING SITES;

ARGININE; CALCIUM; GLUTAMIC ACID; LYSINE; PROTEIN P53; PROTEIN S100B; NERVE GROWTH FACTOR; PROTEIN BINDING; PROTEIN S 100;

ALPHA HELIX; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; ELECTRICITY; ENERGY; ENTROPY; MOLECULAR RECOGNITION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIMULATION; SURFACE CHARGE; THERMODYNAMICS; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; KINETICS; NUCLEAR MAGNETIC RESONANCE; SURFACE PROPERTY;

COMPUTER SIMULATION; KINETICS; MODELS, MOLECULAR; NERVE GROWTH FACTORS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; S100 CALCIUM BINDING PROTEIN BETA SUBUNIT; S100 PROTEINS; SURFACE PROPERTIES; THERMODYNAMICS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 67949106402     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja809547p     Document Type: Article

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