메뉴 건너뛰기




Volumn 72, Issue 2, 2012, Pages 167-174

Accelerating progress in induced pluripotent stem cell research for neurological diseases

Author keywords

[No Author keywords available]

Indexed keywords

ADRENOLEUKODYSTROPHY; ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BECKER MUSCULAR DYSTROPHY; DEGENERATIVE DISEASE; DISEASE MODEL; DUCHENNE MUSCULAR DYSTROPHY; FRAGILE X SYNDROME; FRIEDREICH ATAXIA; GAUCHER DISEASE; HUMAN; HUNTINGTON CHOREA; LESCH NYHAN SYNDROME; MACHADO JOSEPH DISEASE; NERVE CELL; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NONHUMAN; NUCLEAR REPROGRAMMING; PARKINSON DISEASE; PATHOGENESIS; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REGENERATIVE MEDICINE; SCHIZOPHRENIA; SPINAL MUSCULAR ATROPHY; STEM CELL RESEARCH;

EID: 84865612436     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.23596     Document Type: Article
Times cited : (35)

References (70)
  • 1
    • 33747195353 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
    • DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
    • Takahashi K, Yamanaka S,. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-676. (Pubitemid 44233629)
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 2
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline-competent induced pluripotent stem cells
    • DOI 10.1038/nature05934, PII NATURE05934
    • Okita K, Ichisaka T, Yamanaka S,. Generation of germline-competent induced pluripotent stem cells. Nature 2007; 448: 313-317. (Pubitemid 47080336)
    • (2007) Nature , vol.448 , Issue.7151 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 4
    • 36248966518 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
    • DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
    • Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131: 861-872. (Pubitemid 350138099)
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 5
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 2007; 318: 1917-1920.
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3
  • 6
    • 66049135249 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells using recombinant proteins
    • Zhou H, Wu S, Joo JY, et al. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 2009; 4: 381-384.
    • (2009) Cell Stem Cell , vol.4 , pp. 381-384
    • Zhou, H.1    Wu, S.2    Joo, J.Y.3
  • 7
    • 66049143859 scopus 로고    scopus 로고
    • Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
    • Kim D, Kim CH, Moon JI, et al. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 2009; 4: 472-476.
    • (2009) Cell Stem Cell , vol.4 , pp. 472-476
    • Kim, D.1    Kim, C.H.2    Moon, J.I.3
  • 8
    • 55849117368 scopus 로고    scopus 로고
    • Generation of mouse induced pluripotent stem cells without viral vectors
    • Okita K, Nakagawa M, Hyenjong H, et al. Generation of mouse induced pluripotent stem cells without viral vectors. Science 2008; 322: 949-953.
    • (2008) Science , vol.322 , pp. 949-953
    • Okita, K.1    Nakagawa, M.2    Hyenjong, H.3
  • 9
    • 77749320143 scopus 로고    scopus 로고
    • Generation of mouse-induced pluripotent stem cells with plasmid vectors
    • Okita K, Hong H, Takahashi K, Yamanaka S,. Generation of mouse-induced pluripotent stem cells with plasmid vectors. Nat Protoc 2010; 5: 418-428.
    • (2010) Nat Protoc , vol.5 , pp. 418-428
    • Okita, K.1    Hong, H.2    Takahashi, K.3    Yamanaka, S.4
  • 10
    • 80052157957 scopus 로고    scopus 로고
    • Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors
    • Ban H, Nishishita N, Fusaki N, et al. Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. Proc Natl Acad Sci U S A 2011; 108: 14234-14239.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 14234-14239
    • Ban, H.1    Nishishita, N.2    Fusaki, N.3
  • 11
    • 70450265981 scopus 로고    scopus 로고
    • Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
    • Fusaki N, Ban H, Nishiyama A, et al. Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc Jpn Acad Ser B Phys Biol Sci 2009; 85: 348-362.
    • (2009) Proc Jpn Acad ser B Phys Biol Sci , vol.85 , pp. 348-362
    • Fusaki, N.1    Ban, H.2    Nishiyama, A.3
  • 12
    • 66149160608 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs promote induced pluripotency
    • Judson RL, Babiarz JE, Venere M, Blelloch R,. Embryonic stem cell-specific microRNAs promote induced pluripotency. Nat Biotechnol 2009; 27: 459-461.
    • (2009) Nat Biotechnol , vol.27 , pp. 459-461
    • Judson, R.L.1    Babiarz, J.E.2    Venere, M.3    Blelloch, R.4
  • 13
    • 79957855262 scopus 로고    scopus 로고
    • Reprogramming of mouse and human cells to pluripotency using mature microRNAs
    • Miyoshi N, Ishii H, Nagano H, et al. Reprogramming of mouse and human cells to pluripotency using mature microRNAs. Cell Stem Cell 2011; 8: 633-638.
    • (2011) Cell Stem Cell , vol.8 , pp. 633-638
    • Miyoshi, N.1    Ishii, H.2    Nagano, H.3
  • 14
    • 46949085597 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
    • DOI 10.1038/nbt1418, PII NBT1418
    • Huangfu D, Maehr R, Guo W, et al. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol 2008; 26: 795-797. (Pubitemid 351961456)
    • (2008) Nature Biotechnology , vol.26 , Issue.7 , pp. 795-797
    • Huangfu, D.1    Maehr, R.2    Guo, W.3    Eijkelenboom, A.4    Snitow, M.5    Chen, A.E.6    Melton, D.A.7
  • 15
    • 79958292714 scopus 로고    scopus 로고
    • Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
    • Maekawa M, Yamaguchi K, Nakamura T, et al. Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1. Nature 2011; 474: 225-229.
    • (2011) Nature , vol.474 , pp. 225-229
    • Maekawa, M.1    Yamaguchi, K.2    Nakamura, T.3
  • 16
    • 69349100179 scopus 로고    scopus 로고
    • Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
    • Hong H, Takahashi K, Ichisaka T, et al. Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 2009; 460: 1132-1135.
    • (2009) Nature , vol.460 , pp. 1132-1135
    • Hong, H.1    Takahashi, K.2    Ichisaka, T.3
  • 17
    • 55749089875 scopus 로고    scopus 로고
    • Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes
    • Aasen T, Raya A, Barrero MJ, et al. Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nat Biotechnol 2008; 26: 1276-1284.
    • (2008) Nat Biotechnol , vol.26 , pp. 1276-1284
    • Aasen, T.1    Raya, A.2    Barrero, M.J.3
  • 18
    • 70349687407 scopus 로고    scopus 로고
    • Direct reprogramming of human neural stem cells by OCT4
    • Kim JB, Greber B, Arauzo-Bravo MJ, et al. Direct reprogramming of human neural stem cells by OCT4. Nature 2009; 461: 649-643.
    • (2009) Nature , vol.461 , pp. 649-643
    • Kim, J.B.1    Greber, B.2    Arauzo-Bravo, M.J.3
  • 19
    • 77957671713 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells
    • Seki T, Yuasa S, Oda M, et al. Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells. Cell Stem Cell 2010; 7: 11-14.
    • (2010) Cell Stem Cell , vol.7 , pp. 11-14
    • Seki, T.1    Yuasa, S.2    Oda, M.3
  • 20
    • 79952710923 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: A new revolution for clinical neurology?
    • Mattis VB, Svendsen CN,. Induced pluripotent stem cells: a new revolution for clinical neurology? Lancet Neurol 2011; 10: 383-394.
    • (2011) Lancet Neurol , vol.10 , pp. 383-394
    • Mattis, V.B.1    Svendsen, C.N.2
  • 21
    • 50149098605 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
    • Dimos JT, Rodolfa KT, Niakan KK, et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 2008; 321: 1218-1221.
    • (2008) Science , vol.321 , pp. 1218-1221
    • Dimos, J.T.1    Rodolfa, K.T.2    Niakan, K.K.3
  • 22
    • 50549089957 scopus 로고    scopus 로고
    • Disease-specific induced pluripotent stem cells
    • Park IH, Arora N, Huo H, et al. Disease-specific induced pluripotent stem cells. Cell 2008; 134: 877-886.
    • (2008) Cell , vol.134 , pp. 877-886
    • Park, I.H.1    Arora, N.2    Huo, H.3
  • 23
    • 58249110796 scopus 로고    scopus 로고
    • Induced pluripotent stem cells from a spinal muscular atrophy patient
    • Ebert AD, Yu J, Rose FF Jr, et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 2009; 457: 277-280.
    • (2009) Nature , vol.457 , pp. 277-280
    • Ebert, A.D.1    Yu, J.2    Rose, Jr.F.F.3
  • 24
    • 84873337576 scopus 로고    scopus 로고
    • Characterization of human Huntington's disease cell model from induced pluripotent stem cells
    • Zhang N, An MC, Montoro D, Ellerby LM,. Characterization of human Huntington's disease cell model from induced pluripotent stem cells. PLoS Curr 2010; 2: RRN1193.
    • (2010) PLoS Curr , vol.2
    • Zhang, N.1    An, M.C.2    Montoro, D.3    Ellerby, L.M.4
  • 25
    • 79956016292 scopus 로고    scopus 로고
    • Huntington's and myotonic dystrophy hESCs: Down-regulated trinucleotide repeat instability and mismatch repair machinery expression upon differentiation
    • Seriola A, Spits C, Simard JP, et al. Huntington's and myotonic dystrophy hESCs: down-regulated trinucleotide repeat instability and mismatch repair machinery expression upon differentiation. Hum Mol Genet 2011; 20: 176-185.
    • (2011) Hum Mol Genet , vol.20 , pp. 176-185
    • Seriola, A.1    Spits, C.2    Simard, J.P.3
  • 26
    • 78049512763 scopus 로고    scopus 로고
    • Friedreich's ataxia induced pluripotent stem cells model intergenerational GAATTC triplet repeat instability
    • Ku S, Soragni E, Campau E, et al. Friedreich's ataxia induced pluripotent stem cells model intergenerational GAATTC triplet repeat instability. Cell Stem Cell 2010; 7: 631-637.
    • (2010) Cell Stem Cell , vol.7 , pp. 631-637
    • Ku, S.1    Soragni, E.2    Campau, E.3
  • 27
    • 79955884485 scopus 로고    scopus 로고
    • Modelling schizophrenia using human induced pluripotent stem cells
    • Brennand KJ, Simone A, Jou J, et al. Modelling schizophrenia using human induced pluripotent stem cells. Nature 2011; 473: 221-225.
    • (2011) Nature , vol.473 , pp. 221-225
    • Brennand, K.J.1    Simone, A.2    Jou, J.3
  • 28
    • 80052579389 scopus 로고    scopus 로고
    • Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients
    • Jang J, Kang HC, Kim HS, et al. Induced pluripotent stem cell models from X-linked adrenoleukodystrophy patients. Ann Neurol 2011; 70: 402-409.
    • (2011) Ann Neurol , vol.70 , pp. 402-409
    • Jang, J.1    Kang, H.C.2    Kim, H.S.3
  • 29
    • 81255169342 scopus 로고    scopus 로고
    • Modeling familial Alzheimer's disease with induced pluripotent stem cells
    • Yagi T, Ito D, Okada Y, et al. Modeling familial Alzheimer's disease with induced pluripotent stem cells. Hum Mol Genet 2011; 20: 4530-4539.
    • (2011) Hum Mol Genet , vol.20 , pp. 4530-4539
    • Yagi, T.1    Ito, D.2    Okada, Y.3
  • 30
    • 80052225992 scopus 로고    scopus 로고
    • Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients
    • Mitne-Neto M, Machado-Costa M, Marchetto MC, et al. Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients. Hum Mol Genet 2011; 20: 3642-3652.
    • (2011) Hum Mol Genet , vol.20 , pp. 3642-3652
    • Mitne-Neto, M.1    MacHado-Costa, M.2    Marchetto, M.C.3
  • 31
    • 77956214743 scopus 로고    scopus 로고
    • Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells
    • Urbach A, Bar-Nur O, Daley GQ, Benvenisty N,. Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Cell Stem Cell 2010; 6: 407-411.
    • (2010) Cell Stem Cell , vol.6 , pp. 407-411
    • Urbach, A.1    Bar-Nur, O.2    Daley, G.Q.3    Benvenisty, N.4
  • 32
    • 79960833952 scopus 로고    scopus 로고
    • Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations
    • Soldner F, Laganiere J, Cheng AW, et al. Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. Cell 2011; 146: 318-331.
    • (2011) Cell , vol.146 , pp. 318-331
    • Soldner, F.1    Laganiere, J.2    Cheng, A.W.3
  • 33
    • 79952172335 scopus 로고    scopus 로고
    • LRRK2 mutant iPSC-derived da neurons demonstrate increased susceptibility to oxidative stress
    • Nguyen HN, Byers B, Cord B, et al. LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress. Cell Stem Cell 2011; 8: 267-280.
    • (2011) Cell Stem Cell , vol.8 , pp. 267-280
    • Nguyen, H.N.1    Byers, B.2    Cord, B.3
  • 34
    • 79955786943 scopus 로고    scopus 로고
    • Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells
    • Seibler P, Graziotto J, Jeong H, et al. Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells. J Neurosci 2011; 31: 5970-5976.
    • (2011) J Neurosci , vol.31 , pp. 5970-5976
    • Seibler, P.1    Graziotto, J.2    Jeong, H.3
  • 35
    • 80052419902 scopus 로고    scopus 로고
    • Parkinson's disease induced pluripotent stem cells with triplication of the alpha-synuclein locus
    • Devine MJ, Ryten M, Vodicka P, et al. Parkinson's disease induced pluripotent stem cells with triplication of the alpha-synuclein locus. Nat Commun 2011; 2: 440.
    • (2011) Nat Commun , vol.2 , pp. 440
    • Devine, M.J.1    Ryten, M.2    Vodicka, P.3
  • 36
    • 84863393846 scopus 로고    scopus 로고
    • Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells
    • Jiang H, Ren Y, Yuen EY, et al. Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells. Nat Commun 2012; 3: 668.
    • (2012) Nat Commun , vol.3 , pp. 668
    • Jiang, H.1    Ren, Y.2    Yuen, E.Y.3
  • 37
    • 79960009804 scopus 로고    scopus 로고
    • Gaucher disease glucocerebrosidase and alpha-synuclein form a bidirectional pathogenic loop in synucleinopathies
    • Mazzulli JR, Xu YH, Sun Y, et al. Gaucher disease glucocerebrosidase and alpha-synuclein form a bidirectional pathogenic loop in synucleinopathies. Cell 2011; 146: 37-52.
    • (2011) Cell , vol.146 , pp. 37-52
    • Mazzulli, J.R.1    Xu, Y.H.2    Sun, Y.3
  • 38
    • 84856956771 scopus 로고    scopus 로고
    • Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells
    • Israel MA, Yuan SH, Bardy C, et al. Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature 2012; 482: 216-220.
    • (2012) Nature , vol.482 , pp. 216-220
    • Israel, M.A.1    Yuan, S.H.2    Bardy, C.3
  • 39
    • 84355161952 scopus 로고    scopus 로고
    • Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease
    • Koch P, Breuer P, Peitz M, et al. Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease. Nature 2011; 480: 543-546.
    • (2011) Nature , vol.480 , pp. 543-546
    • Koch, P.1    Breuer, P.2    Peitz, M.3
  • 40
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • DOI 10.1126/science.1072994
    • Hardy J, Selkoe DJ,. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002; 297: 353-356. (Pubitemid 34790756)
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 41
    • 13944276825 scopus 로고    scopus 로고
    • Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective
    • DOI 10.1016/j.cell.2005.02.008
    • Tanzi RE, Bertram L,. Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 2005; 120: 545-555. (Pubitemid 40269768)
    • (2005) Cell , vol.120 , Issue.4 , pp. 545-555
    • Tanzi, R.E.1    Bertram, L.2
  • 42
    • 68249087053 scopus 로고    scopus 로고
    • Variation in the safety of induced pluripotent stem cell lines
    • Miura K, Okada Y, Aoi T, et al. Variation in the safety of induced pluripotent stem cell lines. Nat Biotechnol 2009; 27: 743-745.
    • (2009) Nat Biotechnol , vol.27 , pp. 743-745
    • Miura, K.1    Okada, Y.2    Aoi, T.3
  • 43
    • 77955454021 scopus 로고    scopus 로고
    • Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury
    • Tsuji O, Miura K, Okada Y, et al. Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury. Proc Natl Acad Sci U S A 2010; 107: 12704-12709.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 12704-12709
    • Tsuji, O.1    Miura, K.2    Okada, Y.3
  • 44
    • 84873343065 scopus 로고    scopus 로고
    • Steps toward safe cell therapy using induced pluripotent stem cells
    • (in press)
    • Okano H, Nakamura M, Yoshida K, et al. Steps toward safe cell therapy using induced pluripotent stem cells. Circ Res (in press).
    • Circ Res
    • Okano, H.1    Nakamura, M.2    Yoshida, K.3
  • 45
    • 79957807595 scopus 로고    scopus 로고
    • Immunogenicity of induced pluripotent stem cells
    • Zhao T, Zhang ZN, Rong Z, Xu Y,. Immunogenicity of induced pluripotent stem cells. Nature 2011; 474: 212-215.
    • (2011) Nature , vol.474 , pp. 212-215
    • Zhao, T.1    Zhang, Z.N.2    Rong, Z.3    Xu, Y.4
  • 46
    • 76249112734 scopus 로고    scopus 로고
    • Complete Genetic Correction of iPS Cells from Duchenne Muscular Dystrophy
    • Kazuki Y, Hiratsuka M, Takiguchi M, et al. Complete Genetic Correction of iPS Cells From Duchenne Muscular Dystrophy. Mol Ther 2010; 18: 386-393.
    • (2010) Mol Ther , vol.18 , pp. 386-393
    • Kazuki, Y.1    Hiratsuka, M.2    Takiguchi, M.3
  • 47
    • 67649170378 scopus 로고    scopus 로고
    • Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells
    • Zou J, Maeder ML, Mali P, et al. Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell 2009; 5: 97-110.
    • (2009) Cell Stem Cell , vol.5 , pp. 97-110
    • Zou, J.1    Maeder, M.L.2    Mali, P.3
  • 48
    • 70249114821 scopus 로고    scopus 로고
    • Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases
    • Hockemeyer D, Soldner F, Beard C, et al. Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nat Biotechnol 2009; 27: 851-857.
    • (2009) Nat Biotechnol , vol.27 , pp. 851-857
    • Hockemeyer, D.1    Soldner, F.2    Beard, C.3
  • 49
    • 80054987997 scopus 로고    scopus 로고
    • Targeted gene correction of alpha1-antitrypsin deficiency in induced pluripotent stem cells
    • Yusa K, Rashid ST, Strick-Marchand H, et al. Targeted gene correction of alpha1-antitrypsin deficiency in induced pluripotent stem cells. Nature. 2011; 478: 391-394.
    • (2011) Nature , vol.478 , pp. 391-394
    • Yusa, K.1    Rashid, S.T.2    Strick-Marchand, H.3
  • 50
    • 37549030199 scopus 로고    scopus 로고
    • Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
    • Hanna J, Wernig M, Markoulaki S, et al. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 2007; 318: 1920-1923.
    • (2007) Science , vol.318 , pp. 1920-1923
    • Hanna, J.1    Wernig, M.2    Markoulaki, S.3
  • 52
    • 77952884942 scopus 로고    scopus 로고
    • Functional improvement of focal cerebral ischemia injury by subdural transplantation of induced pluripotent stem cells with fibrin glue
    • Chen SJ, Chang CM, Tsai SK, et al. Functional improvement of focal cerebral ischemia injury by subdural transplantation of induced pluripotent stem cells with fibrin glue. Stem Cells Dev 2010; 19: 1757-1767.
    • (2010) Stem Cells Dev , vol.19 , pp. 1757-1767
    • Chen, S.J.1    Chang, C.M.2    Tsai, S.K.3
  • 53
    • 84861903354 scopus 로고    scopus 로고
    • Human Induced Pluripotent Stem Cells form Functional Neurons and Improve Recovery after Grafting in Stroke-Damaged Brain
    • (in press)
    • Oki K, Tatarishvili J, Woods J, et al. Human Induced Pluripotent Stem Cells form Functional Neurons and Improve Recovery After Grafting in Stroke-Damaged Brain. Stem Cells. (in press).
    • Stem Cells.
    • Oki, K.1    Tatarishvili, J.2    Woods, J.3
  • 54
    • 80053628732 scopus 로고    scopus 로고
    • Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice
    • Nori S, Okada Y, Yasuda A, et al. Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice. Proc Natl Acad Sci U S A 2011; 108: 16825-16830.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 16825-16830
    • Nori, S.1    Okada, Y.2    Yasuda, A.3
  • 55
    • 67650077008 scopus 로고    scopus 로고
    • Transmission and spreading of tauopathy in transgenic mouse brain
    • Clavaguera F, Bolmont T, Crowther RA, et al. Transmission and spreading of tauopathy in transgenic mouse brain. Nat Cell Biol 2009; 11: 909-913.
    • (2009) Nat Cell Biol , vol.11 , pp. 909-913
    • Clavaguera, F.1    Bolmont, T.2    Crowther, R.A.3
  • 57
    • 69149089854 scopus 로고    scopus 로고
    • Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein
    • Desplats P, Lee HJ, Bae EJ, et al. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein. Proc Natl Acad Sci U S A 2009; 106: 13010-13015.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 13010-13015
    • Desplats, P.1    Lee, H.J.2    Bae, E.J.3
  • 58
    • 78049376559 scopus 로고    scopus 로고
    • Seeded aggregation and toxicity of {alpha}-synuclein and tau: Cellular models of neurodegenerative diseases
    • Nonaka T, Watanabe ST, Iwatsubo T, Hasegawa M,. Seeded aggregation and toxicity of {alpha}-synuclein and tau: cellular models of neurodegenerative diseases. J Biol Chem 2010; 285: 34885-34898.
    • (2010) J Biol Chem , vol.285 , pp. 34885-34898
    • Nonaka, T.1    Watanabe, S.T.2    Iwatsubo, T.3    Hasegawa, M.4
  • 59
    • 43249114934 scopus 로고    scopus 로고
    • Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
    • DOI 10.1038/nm1747, PII NM1747
    • Kordower JH, Chu Y, Hauser RA, et al. Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease. Nat Med 2008; 14: 504-506. (Pubitemid 351655212)
    • (2008) Nature Medicine , vol.14 , Issue.5 , pp. 504-506
    • Kordower, J.H.1    Chu, Y.2    Hauser, R.A.3    Freeman, T.B.4    Olanow, C.W.5
  • 60
    • 77649162059 scopus 로고    scopus 로고
    • Direct conversion of fibroblasts to functional neurons by defined factors
    • Vierbuchen T, Ostermeier A, Pang ZP, et al. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 2010; 463: 1035-1041.
    • (2010) Nature , vol.463 , pp. 1035-1041
    • Vierbuchen, T.1    Ostermeier, A.2    Pang, Z.P.3
  • 61
    • 79960854285 scopus 로고    scopus 로고
    • Induction of human neuronal cells by defined transcription factors
    • Pang ZP, Yang N, Vierbuchen T, et al. Induction of human neuronal cells by defined transcription factors. Nature 2011; 476: 220-223.
    • (2011) Nature , vol.476 , pp. 220-223
    • Pang, Z.P.1    Yang, N.2    Vierbuchen, T.3
  • 62
    • 80051684096 scopus 로고    scopus 로고
    • MicroRNA-mediated conversion of human fibroblasts to neurons
    • Yoo AS, Sun AX, Li L, et al. MicroRNA-mediated conversion of human fibroblasts to neurons. Nature 2011; 476: 228-231.
    • (2011) Nature , vol.476 , pp. 228-231
    • Yoo, A.S.1    Sun, A.X.2    Li, L.3
  • 63
    • 79961173182 scopus 로고    scopus 로고
    • Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions
    • Ambasudhan R, Talantova M, Coleman R, et al. Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions. Cell Stem Cell 2011; 9: 113-118.
    • (2011) Cell Stem Cell , vol.9 , pp. 113-118
    • Ambasudhan, R.1    Talantova, M.2    Coleman, R.3
  • 64
    • 79956357347 scopus 로고    scopus 로고
    • Direct reprogramming of mouse fibroblasts to neural progenitors
    • Kim J, Efe JA, Zhu S, et al. Direct reprogramming of mouse fibroblasts to neural progenitors. Proc Natl Acad Sci U S A 2011; 108: 7838-7843.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 7838-7843
    • Kim, J.1    Efe, J.A.2    Zhu, S.3
  • 65
    • 84861899082 scopus 로고    scopus 로고
    • Neural stem cells directly differentiated from partially reprogrammed fibroblasts rapidly acquire gliogenic competency
    • (in press)
    • Matsui T, Takano M, Yoshida K, et al. Neural stem cells directly differentiated from partially reprogrammed fibroblasts rapidly acquire gliogenic competency. Stem Cells (in press).
    • Stem Cells
    • Matsui, T.1    Takano, M.2    Yoshida, K.3
  • 66
    • 84857136772 scopus 로고    scopus 로고
    • Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
    • Lujan E, Chanda S, Ahlenius H, et al. Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. Proc Natl Acad Sci U S A 2012; 109: 2527-2532.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 2527-2532
    • Lujan, E.1    Chanda, S.2    Ahlenius, H.3
  • 67
    • 79961131135 scopus 로고    scopus 로고
    • Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons
    • Qiang L, Fujita R, Yamashita T, et al. Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons. Cell 2011; 146: 359-371.
    • (2011) Cell , vol.146 , pp. 359-371
    • Qiang, L.1    Fujita, R.2    Yamashita, T.3
  • 68
    • 80051674431 scopus 로고    scopus 로고
    • Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
    • Caiazzo M, Dell'Anno MT, Dvoretskova E, et al. Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. Nature 2011; 476: 224-227.
    • (2011) Nature , vol.476 , pp. 224-227
    • Caiazzo, M.1    Dell'Anno, M.T.2    Dvoretskova, E.3
  • 69
    • 79959951387 scopus 로고    scopus 로고
    • Direct conversion of human fibroblasts to dopaminergic neurons
    • Pfisterer U, Kirkeby A, Torper O, et al. Direct conversion of human fibroblasts to dopaminergic neurons. Proc Natl Acad Sci U S A 2011; 108: 10343-10348.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 10343-10348
    • Pfisterer, U.1    Kirkeby, A.2    Torper, O.3
  • 70
    • 80052295767 scopus 로고    scopus 로고
    • Conversion of mouse and human fibroblasts into functional spinal motor neurons
    • Son EY, Ichida JK, Wainger BJ, et al. Conversion of mouse and human fibroblasts into functional spinal motor neurons. Cell Stem Cell 2011; 9: 205-218.
    • (2011) Cell Stem Cell , vol.9 , pp. 205-218
    • Son, E.Y.1    Ichida, J.K.2    Wainger, B.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.