-
1
-
-
0025908557
-
The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor
-
Wiley H.S., et al. The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor. J. Biol. Chem. 1991, 266:11083-11094.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 11083-11094
-
-
Wiley, H.S.1
-
2
-
-
0031059468
-
Regulatory mechanisms that modulate signalling by G-protein-coupled receptors
-
Bo S.K., et al. Regulatory mechanisms that modulate signalling by G-protein-coupled receptors. Biochem. J. 1997, 322:1-18.
-
(1997)
Biochem. J.
, vol.322
, pp. 1-18
-
-
Bo, S.K.1
-
3
-
-
3142592401
-
Not just a sink: endosomes in control of signal transduction
-
Miaczynska M., et al. Not just a sink: endosomes in control of signal transduction. Curr. Opin. Cell Biol. 2004, 16:400-406.
-
(2004)
Curr. Opin. Cell Biol.
, vol.16
, pp. 400-406
-
-
Miaczynska, M.1
-
4
-
-
0842333853
-
Signaling endosome hypothesis: a cellular mechanism for long distance communication
-
Howe C.L., Mobley W.C. Signaling endosome hypothesis: a cellular mechanism for long distance communication. J. Neurobiol. 2004, 58:207-216.
-
(2004)
J. Neurobiol.
, vol.58
, pp. 207-216
-
-
Howe, C.L.1
Mobley, W.C.2
-
5
-
-
13444263549
-
Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling
-
Le Roy C., Wrana J.L. Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling. Nat. Rev. Mol. Cell Biol. 2005, 6:112-126.
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 112-126
-
-
Le Roy, C.1
Wrana, J.L.2
-
6
-
-
33644769212
-
Endocytosis conducts the cell signaling orchestra
-
Polo S., Di Fiore P.P. Endocytosis conducts the cell signaling orchestra. Cell 2006, 124:897-900.
-
(2006)
Cell
, vol.124
, pp. 897-900
-
-
Polo, S.1
Di Fiore, P.P.2
-
7
-
-
84858000255
-
Modeling the signaling endosome hypothesis: why a drive to the nucleus is better than a (random) walk
-
Howe C.L. Modeling the signaling endosome hypothesis: why a drive to the nucleus is better than a (random) walk. Theor. Biol. Med. Model. 2005, 15:1-15.
-
(2005)
Theor. Biol. Med. Model.
, vol.15
, pp. 1-15
-
-
Howe, C.L.1
-
8
-
-
78650484935
-
Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes
-
Taelman V.F., et al. Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes. Cell 2010, 143:1136-1148.
-
(2010)
Cell
, vol.143
, pp. 1136-1148
-
-
Taelman, V.F.1
-
9
-
-
84355162786
-
Endocytic control of growth factor signalling: multivesicular bodies as signalling organelles
-
Dobrowolski R., De Robertis E.M. Endocytic control of growth factor signalling: multivesicular bodies as signalling organelles. Nat. Rev. Mol. Cell Biol. 2011, 13:53-60.
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 53-60
-
-
Dobrowolski, R.1
De Robertis, E.M.2
-
10
-
-
80052231028
-
Regulation of developmental intercellular signalling by intracellular trafficking
-
Shilo B.-Z., Schejter E.D. Regulation of developmental intercellular signalling by intracellular trafficking. EMBO J. 2011, 30:3516-3526.
-
(2011)
EMBO J.
, vol.30
, pp. 3516-3526
-
-
Shilo, B.-Z.1
Schejter, E.D.2
-
11
-
-
68549087161
-
Scaffolds: interaction platforms for cellular signalling circuits
-
Zeke A., et al. Scaffolds: interaction platforms for cellular signalling circuits. Trends Cell Biol. 2009, 19:364-374.
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 364-374
-
-
Zeke, A.1
-
12
-
-
62049084764
-
The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes
-
Nada S., et al. The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes. EMBO J. 2009, 28:477-489.
-
(2009)
EMBO J.
, vol.28
, pp. 477-489
-
-
Nada, S.1
-
13
-
-
33845709128
-
P14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis
-
Teis D., et al. p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis. J. Cell Biol. 2006, 175:861-868.
-
(2006)
J. Cell Biol.
, vol.175
, pp. 861-868
-
-
Teis, D.1
-
14
-
-
78449282900
-
Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts
-
Stasyk T., et al. Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts. Proteomics 2010, 10:4117-41127.
-
(2010)
Proteomics
, vol.10
, pp. 4117-41127
-
-
Stasyk, T.1
-
15
-
-
77951768486
-
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
-
Sancak Y., et al. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell 2010, 141:290-303.
-
(2010)
Cell
, vol.141
, pp. 290-303
-
-
Sancak, Y.1
-
16
-
-
0037124028
-
Early endosomal regulation of Smad-dependent signaling in endothelial cells
-
Panopoulou E., et al. Early endosomal regulation of Smad-dependent signaling in endothelial cells. J. Biol. Chem. 2002, 277:18046-18052.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18046-18052
-
-
Panopoulou, E.1
-
17
-
-
34248149074
-
Endofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signaling
-
Chen Y.-G., et al. Endofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signaling. J. Biol. Chem. 2007, 282:9688-9695.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 9688-9695
-
-
Chen, Y.-G.1
-
18
-
-
33746363486
-
Domains, motifs, and scaffolds: the role of modular interactions in the evolution and wiring of cell signaling circuits
-
Bhattacharyya R.P., et al. Domains, motifs, and scaffolds: the role of modular interactions in the evolution and wiring of cell signaling circuits. Annu. Rev. Biochem. 2006, 75:655-680.
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 655-680
-
-
Bhattacharyya, R.P.1
-
19
-
-
13444278821
-
Reconstruction of cellular signalling networks and analysis of their properties
-
Papin J.A., et al. Reconstruction of cellular signalling networks and analysis of their properties. Nat. Rev. Mol. Cell Biol. 2005, 6:99-111.
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 99-111
-
-
Papin, J.A.1
-
20
-
-
1842507650
-
Axin: a master scaffold for multiple signaling pathways
-
Luo W., Lin S.-C. Axin: a master scaffold for multiple signaling pathways. Neurosignals 2004, 13:99-113.
-
(2004)
Neurosignals
, vol.13
, pp. 99-113
-
-
Luo, W.1
Lin, S.-C.2
-
21
-
-
35649013184
-
MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3β
-
Abell A.N., et al. MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3β. J. Biol. Chem. 2007, 282:30476-30484.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 30476-30484
-
-
Abell, A.N.1
-
22
-
-
0037513408
-
A role of Dishevelled in relocating Axin to the plasma membrane during wingless signaling
-
Cliffe A., et al. A role of Dishevelled in relocating Axin to the plasma membrane during wingless signaling. Curr. Biol. 2003, 13:960-966.
-
(2003)
Curr. Biol.
, vol.13
, pp. 960-966
-
-
Cliffe, A.1
-
23
-
-
34250827150
-
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
-
Bilic J., et al. Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation. Science 2007, 316:1619-1622.
-
(2007)
Science
, vol.316
, pp. 1619-1622
-
-
Bilic, J.1
-
24
-
-
0034947962
-
Axin facilitates Smad3 activation in the transforming growth factor β signaling pathway
-
Furuhashi M., et al. Axin facilitates Smad3 activation in the transforming growth factor β signaling pathway. Mol. Cell. Biol. 2001, 21:5132-5141.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5132-5141
-
-
Furuhashi, M.1
-
25
-
-
42949092018
-
The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development
-
Schenck A., et al. The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development. Cell 2008, 133:486-497.
-
(2008)
Cell
, vol.133
, pp. 486-497
-
-
Schenck, A.1
-
26
-
-
78951483248
-
Early endosomal antigen 1 (EEA1) is an obligate scaffold for angiotensin ii-induced, PKC-α-dependent Akt activation in endosomes
-
Nazarewicz R.R., et al. Early endosomal antigen 1 (EEA1) is an obligate scaffold for angiotensin ii-induced, PKC-α-dependent Akt activation in endosomes. J. Biol. Chem. 2011, 286:2886-2895.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 2886-2895
-
-
Nazarewicz, R.R.1
-
27
-
-
80054835350
-
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hgs) is involved in BMP signaling through phosphorylation of smads and TAK1 in early mouse embryo
-
Miura S., Mishina Y. Hepatocyte growth factor-regulated tyrosine kinase substrate (Hgs) is involved in BMP signaling through phosphorylation of smads and TAK1 in early mouse embryo. Dev. Dyn. 2011, 240:2474-2481.
-
(2011)
Dev. Dyn.
, vol.240
, pp. 2474-2481
-
-
Miura, S.1
Mishina, Y.2
-
28
-
-
0037223971
-
The evolution of signalling pathways in animal development
-
Pires-daSilva A., Sommer R.J. The evolution of signalling pathways in animal development. Nat. Rev. Genet. 2003, 4:39-49.
-
(2003)
Nat. Rev. Genet.
, vol.4
, pp. 39-49
-
-
Pires-daSilva, A.1
Sommer, R.J.2
-
29
-
-
0032869218
-
1998 Warkany lecture: signaling pathways in development
-
Gerhart J. 1998 Warkany lecture: signaling pathways in development. Teratology 1999, 60:226-239.
-
(1999)
Teratology
, vol.60
, pp. 226-239
-
-
Gerhart, J.1
-
30
-
-
62849094483
-
Navigating the network: signaling cross-talk in hematopoietic cells
-
Fraser I.D.C., Germain R.N. Navigating the network: signaling cross-talk in hematopoietic cells. Nat. Immunol. 2009, 10:327-331.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 327-331
-
-
Fraser, I.D.C.1
Germain, R.N.2
-
31
-
-
33744809296
-
A global analysis of cross-talk in a mammalian cellular signalling network
-
Natarajan M., et al. A global analysis of cross-talk in a mammalian cellular signalling network. Nat. Cell Biol. 2006, 8:571-580.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 571-580
-
-
Natarajan, M.1
-
32
-
-
36249018809
-
Cooperation of signalling pathways in embryonic mammary gland development
-
Robinson G.W. Cooperation of signalling pathways in embryonic mammary gland development. Nat. Rev. Genet. 2007, 8:963-972.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 963-972
-
-
Robinson, G.W.1
-
33
-
-
34249725570
-
Predictive modeling of signaling crosstalk during C. elegans vulval development
-
Fisher J., et al. Predictive modeling of signaling crosstalk during C. elegans vulval development. PLoS Comput. Biol. 2007, 3:e92.
-
(2007)
PLoS Comput. Biol.
, vol.3
-
-
Fisher, J.1
-
34
-
-
32044451325
-
Cancer: a systems biology disease
-
Hornberg J.J., et al. Cancer: a systems biology disease. Biosystems 2006, 83:81-90.
-
(2006)
Biosystems
, vol.83
, pp. 81-90
-
-
Hornberg, J.J.1
-
35
-
-
33244464562
-
Critical nodes in signalling pathways: insights into insulin action
-
Taniguchi C.M., et al. Critical nodes in signalling pathways: insights into insulin action. Nat. Rev. Mol. Cell Biol. 2006, 7:85-96.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 85-96
-
-
Taniguchi, C.M.1
-
36
-
-
69749086899
-
Identification of rare cancer driver mutations by network reconstruction
-
Torkamani A., Schork N.J. Identification of rare cancer driver mutations by network reconstruction. Genome Res. 2009, 19:1570-1578.
-
(2009)
Genome Res.
, vol.19
, pp. 1570-1578
-
-
Torkamani, A.1
Schork, N.J.2
-
37
-
-
34447122100
-
A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK pathways
-
Kim D., et al. A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK pathways. Oncogene 2007, 26:4571-4579.
-
(2007)
Oncogene
, vol.26
, pp. 4571-4579
-
-
Kim, D.1
-
38
-
-
34548065794
-
How to design multi-target drugs: target search options in cellular networks
-
Korcsmáros T., et al. How to design multi-target drugs: target search options in cellular networks. Expert Opin. Drug Discov. 2007, 2:1-10.
-
(2007)
Expert Opin. Drug Discov.
, vol.2
, pp. 1-10
-
-
Korcsmáros, T.1
-
39
-
-
44249090908
-
Multipathway model enables prediction of kinase inhibitor cross-talk effects on migration of Her2-overexpressing mammary epithelial cells
-
Kumar N., et al. Multipathway model enables prediction of kinase inhibitor cross-talk effects on migration of Her2-overexpressing mammary epithelial cells. Mol. Pharmacol. 2008, 73:1668-1678.
-
(2008)
Mol. Pharmacol.
, vol.73
, pp. 1668-1678
-
-
Kumar, N.1
-
40
-
-
77955444349
-
Uniformly curated signaling pathways reveal tissue-specific cross-talks and support drug target discovery
-
Korcsmáros T., et al. Uniformly curated signaling pathways reveal tissue-specific cross-talks and support drug target discovery. Bioinformatics 2010, 26:2042-2050.
-
(2010)
Bioinformatics
, vol.26
, pp. 2042-2050
-
-
Korcsmáros, T.1
-
41
-
-
77955802924
-
Ultrasensitive responses and specificity in cell signaling
-
Haney S., et al. Ultrasensitive responses and specificity in cell signaling. BMC Syst. Biol. 2010, 4:119.
-
(2010)
BMC Syst. Biol.
, vol.4
, pp. 119
-
-
Haney, S.1
-
42
-
-
28444439900
-
Organelle identity and the signposts for membrane traffic
-
Behnia R., Munro S. Organelle identity and the signposts for membrane traffic. Nature 2005, 438:597-604.
-
(2005)
Nature
, vol.438
, pp. 597-604
-
-
Behnia, R.1
Munro, S.2
-
43
-
-
77954983113
-
Appl1 is essential for the survival of Xenopus pancreas, duodenum, and stomach progenitor cells
-
Wen L., et al. Appl1 is essential for the survival of Xenopus pancreas, duodenum, and stomach progenitor cells. Dev. Dyn. 2010, 239:2198-2207.
-
(2010)
Dev. Dyn.
, vol.239
, pp. 2198-2207
-
-
Wen, L.1
-
44
-
-
78650795768
-
APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway
-
Xin X., et al. APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway. Am. J. Physiol. Endocrinol. Metab. 2011, 300:E103-E110.
-
(2011)
Am. J. Physiol. Endocrinol. Metab.
, vol.300
-
-
Xin, X.1
-
45
-
-
27744577296
-
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
-
Shim J.-H., et al. TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo. Genes Dev. 2005, 19:2668-2681.
-
(2005)
Genes Dev.
, vol.19
, pp. 2668-2681
-
-
Shim, J.-H.1
-
46
-
-
58149193222
-
Human Protein Reference Database - 2009 update
-
Prasad T.S.K., et al. Human Protein Reference Database - 2009 update. Nucleic Acids Res. 2009, 37:D767-D772.
-
(2009)
Nucleic Acids Res.
, vol.37
-
-
Prasad, T.S.K.1
-
47
-
-
84859699831
-
The Gene Ontology: enhancements for 2011
-
The Gene Ontology Consortium
-
The Gene Ontology Consortium The Gene Ontology: enhancements for 2011. Nucleic Acids Res. 2012, 40:D559-D564.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
-
48
-
-
78651328883
-
The BioGRID Interaction Database: 2011 update
-
Stark C., et al. The BioGRID Interaction Database: 2011 update. Nucleic Acids Res. 2011, 39:D698-D704.
-
(2011)
Nucleic Acids Res.
, vol.39
-
-
Stark, C.1
-
49
-
-
78651324347
-
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
-
Szklarczyk D., et al. The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored. Nucleic Acids Res. 2011, 39:D561-D568.
-
(2011)
Nucleic Acids Res.
, vol.39
-
-
Szklarczyk, D.1
-
50
-
-
25144498379
-
A human protein-protein interaction network: a resource for annotating the proteome
-
Stelzl U., et al. A human protein-protein interaction network: a resource for annotating the proteome. Cell 2005, 122:957-968.
-
(2005)
Cell
, vol.122
, pp. 957-968
-
-
Stelzl, U.1
-
51
-
-
0033607141
-
Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the β1-adrenergic receptor
-
Tang Y., et al. Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the β1-adrenergic receptor. Proc. Natl Acad. Sci. U.S.A. 1999, 96:12559-12564.
-
(1999)
Proc. Natl Acad. Sci. U.S.A.
, vol.96
, pp. 12559-12564
-
-
Tang, Y.1
-
52
-
-
0037075547
-
Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors
-
Soubeyran P., et al. Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. Nature 2002, 416:183-187.
-
(2002)
Nature
, vol.416
, pp. 183-187
-
-
Soubeyran, P.1
-
53
-
-
0842307321
-
Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein
-
Yam J.W.P., et al. Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein. Blood 2004, 103:1445-1453.
-
(2004)
Blood
, vol.103
, pp. 1445-1453
-
-
Yam, J.W.P.1
-
54
-
-
3543143101
-
Functional proteomics mapping of a human signaling pathway
-
Colland F., et al. Functional proteomics mapping of a human signaling pathway. Genome Res. 2004, 7:1324-1332.
-
(2004)
Genome Res.
, vol.7
, pp. 1324-1332
-
-
Colland, F.1
-
55
-
-
79951855236
-
Compartmentalized CDK2 is connected with SHP-1 and β-catenin and regulates insulin internalization
-
Fiset A., et al. Compartmentalized CDK2 is connected with SHP-1 and β-catenin and regulates insulin internalization. Cell. Signal. 2011, 23:911-919.
-
(2011)
Cell. Signal.
, vol.23
, pp. 911-919
-
-
Fiset, A.1
-
56
-
-
67650540827
-
Endosomal adaptor proteins APPL1 and APPL2 are novel activators of β-catenin/TCF-mediated transcription
-
Rashid S., et al. Endosomal adaptor proteins APPL1 and APPL2 are novel activators of β-catenin/TCF-mediated transcription. J. Biol. Chem. 2009, 284:18115-18128.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 18115-18128
-
-
Rashid, S.1
-
57
-
-
77950553992
-
Smad3 prevents β-catenin degradation and facilitates β-catenin nuclear translocation in chondrocytes
-
Zhang M., et al. Smad3 prevents β-catenin degradation and facilitates β-catenin nuclear translocation in chondrocytes. J. Biol. Chem. 2010, 285:8703-8710.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 8703-8710
-
-
Zhang, M.1
-
58
-
-
77952903562
-
Signalling ballet in space and time
-
Kholodenko B.N., et al. Signalling ballet in space and time. Nat. Rev. Mol. Cell Biol. 2010, 11:414-426.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 414-426
-
-
Kholodenko, B.N.1
-
59
-
-
40849100220
-
Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics
-
Bashor C.J., et al. Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics. Science 2008, 319:1539-1543.
-
(2008)
Science
, vol.319
, pp. 1539-1543
-
-
Bashor, C.J.1
-
60
-
-
77952944052
-
Designing customized cell signalling circuits
-
Lim W.A. Designing customized cell signalling circuits. Nat. Rev. Mol. Cell Biol. 2010, 11:393-403.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 393-403
-
-
Lim, W.A.1
-
61
-
-
62849097694
-
New roles for endosomes: from vesicular carriers to multi-purpose platforms
-
Gould G.W., Lippincott-Schwartz J. New roles for endosomes: from vesicular carriers to multi-purpose platforms. Nat. Rev. Mol. Cell Biol. 2009, 10:287-292.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 287-292
-
-
Gould, G.W.1
Lippincott-Schwartz, J.2
-
62
-
-
0036787904
-
Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival
-
Wang Y., et al. Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival. Mol. Cell. Biol. 2002, 22:7279-7290.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7279-7290
-
-
Wang, Y.1
-
63
-
-
70449552889
-
Endosomes: a legitimate platform for the signaling train
-
Murphy J.E., et al. Endosomes: a legitimate platform for the signaling train. Proc. Natl Acad. Sci. U.S.A. 2009, 106:17615-17622.
-
(2009)
Proc. Natl Acad. Sci. U.S.A.
, vol.106
, pp. 17615-17622
-
-
Murphy, J.E.1
-
64
-
-
84860428078
-
Endocytic trafficking of neurotrophins in neural development
-
Ascano M., et al. Endocytic trafficking of neurotrophins in neural development. Trends Cell Biol. 2012, 22:266-273.
-
(2012)
Trends Cell Biol.
, vol.22
, pp. 266-273
-
-
Ascano, M.1
-
65
-
-
47749089820
-
Regulation of TNFR1 and CD95 signalling by receptor compartmentalization
-
Schütze S., et al. Regulation of TNFR1 and CD95 signalling by receptor compartmentalization. Nat. Rev. Mol. Cell Biol. 2008, 9:655-662.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 655-662
-
-
Schütze, S.1
-
66
-
-
79960081111
-
The STAT3 beacon: IL-6 recurrently activates STAT 3 from endosomal structures
-
German C.L., et al. The STAT3 beacon: IL-6 recurrently activates STAT 3 from endosomal structures. Exp. Cell Res. 2011, 317:1955-1969.
-
(2011)
Exp. Cell Res.
, vol.317
, pp. 1955-1969
-
-
German, C.L.1
-
67
-
-
35048878660
-
Live cell imaging of interleukin-6-induced targeting of " transcription factor" STAT3 to sequestering endosomes in the cytoplasm
-
Xu F., et al. Live cell imaging of interleukin-6-induced targeting of " transcription factor" STAT3 to sequestering endosomes in the cytoplasm. Am. J Physiol. Cell Physiol. 2007, 293:C1374-C1382.
-
(2007)
Am. J Physiol. Cell Physiol.
, vol.293
-
-
Xu, F.1
-
68
-
-
84872212844
-
Spatiotemporal regulation of MyD88 - IRF-7 signalling for robust type-I interferon induction
-
Ohba Y., et al. Spatiotemporal regulation of MyD88 - IRF-7 signalling for robust type-I interferon induction. Nature 2005, 2:1-6.
-
(2005)
Nature
, vol.2
, pp. 1-6
-
-
Ohba, Y.1
-
69
-
-
51649130231
-
Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation
-
Kermorgant S., Parker P.J. Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation. J. Cell Biol. 2008, 182:855-863.
-
(2008)
J. Cell Biol.
, vol.182
, pp. 855-863
-
-
Kermorgant, S.1
Parker, P.J.2
-
70
-
-
77952382637
-
Endocytic pathway is required for Drosophila Toll innate immune signaling
-
Huang H.-R., et al. Endocytic pathway is required for Drosophila Toll innate immune signaling. Proc. Natl Acad. Sci. U.S.A. 2010, 107:8322-8327.
-
(2010)
Proc. Natl Acad. Sci. U.S.A.
, vol.107
, pp. 8322-8327
-
-
Huang, H.-R.1
-
71
-
-
35649018124
-
The endocytic control of JAK/STAT signalling in Drosophila
-
Devergne O., et al. The endocytic control of JAK/STAT signalling in Drosophila. J. Cell Sci. 2007, 120:3457-3464.
-
(2007)
J. Cell Sci.
, vol.120
, pp. 3457-3464
-
-
Devergne, O.1
-
72
-
-
78049363486
-
Negative regulation of Drosophila JAK-STAT signalling by endocytic trafficking
-
Vidal O.M., et al. Negative regulation of Drosophila JAK-STAT signalling by endocytic trafficking. J. Cell Sci. 2010, 123:3457-3466.
-
(2010)
J. Cell Sci.
, vol.123
, pp. 3457-3466
-
-
Vidal, O.M.1
-
73
-
-
33846109356
-
A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14
-
Bohn G., et al. A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14. Nat. Med. 2007, 13:38-45.
-
(2007)
Nat. Med.
, vol.13
, pp. 38-45
-
-
Bohn, G.1
-
74
-
-
34547750315
-
Endosomal transport of neurotrophins: roles in signaling and neurodegenerative diseases
-
Bronfman F.C., et al. Endosomal transport of neurotrophins: roles in signaling and neurodegenerative diseases. Dev. Neurobiol. 2007, 67:1183-1203.
-
(2007)
Dev. Neurobiol.
, vol.67
, pp. 1183-1203
-
-
Bronfman, F.C.1
-
75
-
-
56149094041
-
Endocytosis and cancer: an " insider" network with dangerous liaisons
-
Lanzetti L., Di Fiore P.P. Endocytosis and cancer: an " insider" network with dangerous liaisons. Traffic 2008, 9:2011-2021.
-
(2008)
Traffic
, vol.9
, pp. 2011-2021
-
-
Lanzetti, L.1
Di Fiore, P.P.2
-
76
-
-
0032797695
-
Differential expression of RAB5A in human lung adenocarcinoma cells with different metastasis potential
-
Yu L., et al. Differential expression of RAB5A in human lung adenocarcinoma cells with different metastasis potential. Clin. Exp. Metastasis 1999, 17:213-219.
-
(1999)
Clin. Exp. Metastasis
, vol.17
, pp. 213-219
-
-
Yu, L.1
-
77
-
-
34548649469
-
Expression of Rab5a in hepatocellular carcinoma: possible involvement in epidermal growth factor signaling
-
Fukui K., et al. Expression of Rab5a in hepatocellular carcinoma: possible involvement in epidermal growth factor signaling. Hepatol. Res. 2007, 37:957-965.
-
(2007)
Hepatol. Res.
, vol.37
, pp. 957-965
-
-
Fukui, K.1
-
78
-
-
44449127738
-
Endosomal sorting complex required for transport proteins in cancer pathogenesis, vesicular transport, and non-endosomal functions
-
Tanaka N., et al. Endosomal sorting complex required for transport proteins in cancer pathogenesis, vesicular transport, and non-endosomal functions. Cancer Sci. 2008, 99:1293-1303.
-
(2008)
Cancer Sci.
, vol.99
, pp. 1293-1303
-
-
Tanaka, N.1
-
79
-
-
34547114456
-
Pathways of clathrin-independent endocytosis
-
Mayor S., Pagano R.E. Pathways of clathrin-independent endocytosis. Nat. Rev. Mol. Cell Biol. 2007, 8:603-612.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 603-612
-
-
Mayor, S.1
Pagano, R.E.2
-
80
-
-
38549092474
-
Membrane recognition by phospholipid-binding domains
-
Lemmon M.A. Membrane recognition by phospholipid-binding domains. Nat. Rev. Mol. Cell Biol. 2008, 9:99-111.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 99-111
-
-
Lemmon, M.A.1
-
81
-
-
30944461203
-
Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions
-
Michell R.H., et al. Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions. Trends Biochem. Sci. 2006, 31:52-63.
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 52-63
-
-
Michell, R.H.1
-
82
-
-
72549101543
-
Finding scaffold proteins in interactomes
-
Ramírez F., Albrecht M. Finding scaffold proteins in interactomes. Trends Cell Biol. 2010, 20:2-4.
-
(2010)
Trends Cell Biol.
, vol.20
, pp. 2-4
-
-
Ramírez, F.1
Albrecht, M.2
-
83
-
-
84858077472
-
The Pfam protein families database
-
Punta M., et al. The Pfam protein families database. Nucleic Acids Res. 2012, 40:D290-D301.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Punta, M.1
-
84
-
-
84862192725
-
The UniProt-GO Annotation database in 2011
-
Dimmer E.C., et al. The UniProt-GO Annotation database in 2011. Nucleic Acids Res. 2012, 40:D565-D570.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Dimmer, E.C.1
-
85
-
-
84860439064
-
Linking proteins to signaling pathways for experiment design and evaluation
-
Farkas I.J., et al. Linking proteins to signaling pathways for experiment design and evaluation. PLoS ONE 2012, 7:e36202.
-
(2012)
PLoS ONE
, vol.7
-
-
Farkas, I.J.1
-
86
-
-
84858983547
-
KEGG for integration and interpretation of large-scale molecular data sets
-
Kanehisa M., et al. KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res. 2012, 40:D109-D114.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Kanehisa, M.1
-
87
-
-
78651275182
-
Reactome: a database of reactions, pathways and biological processes
-
Croft D., et al. Reactome: a database of reactions, pathways and biological processes. Nucleic Acids Res. 2011, 39:D691-D697.
-
(2011)
Nucleic Acids Res.
, vol.39
-
-
Croft, D.1
|