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Volumn 22, Issue 9, 2012, Pages 447-456

Endosomal crosstalk: Meeting points for signaling pathways

Author keywords

[No Author keywords available]

Indexed keywords

AXIN; EPIDERMAL GROWTH FACTOR RECEPTOR; JANUS KINASE; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITIDE; PROTEIN CCNE1; PROTEIN GRB1; PROTEOME; SCAFFOLD PROTEIN; SMAD ANCHOR FOR RECEPTOR ACTIVATION; SONIC HEDGEHOG PROTEIN; STAT PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 84865599600     PISSN: 09628924     EISSN: 18793088     Source Type: Journal    
DOI: 10.1016/j.tcb.2012.06.004     Document Type: Review
Times cited : (97)

References (88)
  • 1
    • 0025908557 scopus 로고
    • The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor
    • Wiley H.S., et al. The role of tyrosine kinase activity in endocytosis, compartmentation, and down-regulation of the epidermal growth factor receptor. J. Biol. Chem. 1991, 266:11083-11094.
    • (1991) J. Biol. Chem. , vol.266 , pp. 11083-11094
    • Wiley, H.S.1
  • 2
    • 0031059468 scopus 로고    scopus 로고
    • Regulatory mechanisms that modulate signalling by G-protein-coupled receptors
    • Bo S.K., et al. Regulatory mechanisms that modulate signalling by G-protein-coupled receptors. Biochem. J. 1997, 322:1-18.
    • (1997) Biochem. J. , vol.322 , pp. 1-18
    • Bo, S.K.1
  • 3
    • 3142592401 scopus 로고    scopus 로고
    • Not just a sink: endosomes in control of signal transduction
    • Miaczynska M., et al. Not just a sink: endosomes in control of signal transduction. Curr. Opin. Cell Biol. 2004, 16:400-406.
    • (2004) Curr. Opin. Cell Biol. , vol.16 , pp. 400-406
    • Miaczynska, M.1
  • 4
    • 0842333853 scopus 로고    scopus 로고
    • Signaling endosome hypothesis: a cellular mechanism for long distance communication
    • Howe C.L., Mobley W.C. Signaling endosome hypothesis: a cellular mechanism for long distance communication. J. Neurobiol. 2004, 58:207-216.
    • (2004) J. Neurobiol. , vol.58 , pp. 207-216
    • Howe, C.L.1    Mobley, W.C.2
  • 5
    • 13444263549 scopus 로고    scopus 로고
    • Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling
    • Le Roy C., Wrana J.L. Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling. Nat. Rev. Mol. Cell Biol. 2005, 6:112-126.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 112-126
    • Le Roy, C.1    Wrana, J.L.2
  • 6
    • 33644769212 scopus 로고    scopus 로고
    • Endocytosis conducts the cell signaling orchestra
    • Polo S., Di Fiore P.P. Endocytosis conducts the cell signaling orchestra. Cell 2006, 124:897-900.
    • (2006) Cell , vol.124 , pp. 897-900
    • Polo, S.1    Di Fiore, P.P.2
  • 7
    • 84858000255 scopus 로고    scopus 로고
    • Modeling the signaling endosome hypothesis: why a drive to the nucleus is better than a (random) walk
    • Howe C.L. Modeling the signaling endosome hypothesis: why a drive to the nucleus is better than a (random) walk. Theor. Biol. Med. Model. 2005, 15:1-15.
    • (2005) Theor. Biol. Med. Model. , vol.15 , pp. 1-15
    • Howe, C.L.1
  • 8
    • 78650484935 scopus 로고    scopus 로고
    • Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes
    • Taelman V.F., et al. Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes. Cell 2010, 143:1136-1148.
    • (2010) Cell , vol.143 , pp. 1136-1148
    • Taelman, V.F.1
  • 9
    • 84355162786 scopus 로고    scopus 로고
    • Endocytic control of growth factor signalling: multivesicular bodies as signalling organelles
    • Dobrowolski R., De Robertis E.M. Endocytic control of growth factor signalling: multivesicular bodies as signalling organelles. Nat. Rev. Mol. Cell Biol. 2011, 13:53-60.
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 53-60
    • Dobrowolski, R.1    De Robertis, E.M.2
  • 10
    • 80052231028 scopus 로고    scopus 로고
    • Regulation of developmental intercellular signalling by intracellular trafficking
    • Shilo B.-Z., Schejter E.D. Regulation of developmental intercellular signalling by intracellular trafficking. EMBO J. 2011, 30:3516-3526.
    • (2011) EMBO J. , vol.30 , pp. 3516-3526
    • Shilo, B.-Z.1    Schejter, E.D.2
  • 11
    • 68549087161 scopus 로고    scopus 로고
    • Scaffolds: interaction platforms for cellular signalling circuits
    • Zeke A., et al. Scaffolds: interaction platforms for cellular signalling circuits. Trends Cell Biol. 2009, 19:364-374.
    • (2009) Trends Cell Biol. , vol.19 , pp. 364-374
    • Zeke, A.1
  • 12
    • 62049084764 scopus 로고    scopus 로고
    • The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes
    • Nada S., et al. The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes. EMBO J. 2009, 28:477-489.
    • (2009) EMBO J. , vol.28 , pp. 477-489
    • Nada, S.1
  • 13
    • 33845709128 scopus 로고    scopus 로고
    • P14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis
    • Teis D., et al. p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis. J. Cell Biol. 2006, 175:861-868.
    • (2006) J. Cell Biol. , vol.175 , pp. 861-868
    • Teis, D.1
  • 14
    • 78449282900 scopus 로고    scopus 로고
    • Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts
    • Stasyk T., et al. Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts. Proteomics 2010, 10:4117-41127.
    • (2010) Proteomics , vol.10 , pp. 4117-41127
    • Stasyk, T.1
  • 15
    • 77951768486 scopus 로고    scopus 로고
    • Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
    • Sancak Y., et al. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell 2010, 141:290-303.
    • (2010) Cell , vol.141 , pp. 290-303
    • Sancak, Y.1
  • 16
    • 0037124028 scopus 로고    scopus 로고
    • Early endosomal regulation of Smad-dependent signaling in endothelial cells
    • Panopoulou E., et al. Early endosomal regulation of Smad-dependent signaling in endothelial cells. J. Biol. Chem. 2002, 277:18046-18052.
    • (2002) J. Biol. Chem. , vol.277 , pp. 18046-18052
    • Panopoulou, E.1
  • 17
    • 34248149074 scopus 로고    scopus 로고
    • Endofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signaling
    • Chen Y.-G., et al. Endofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signaling. J. Biol. Chem. 2007, 282:9688-9695.
    • (2007) J. Biol. Chem. , vol.282 , pp. 9688-9695
    • Chen, Y.-G.1
  • 18
    • 33746363486 scopus 로고    scopus 로고
    • Domains, motifs, and scaffolds: the role of modular interactions in the evolution and wiring of cell signaling circuits
    • Bhattacharyya R.P., et al. Domains, motifs, and scaffolds: the role of modular interactions in the evolution and wiring of cell signaling circuits. Annu. Rev. Biochem. 2006, 75:655-680.
    • (2006) Annu. Rev. Biochem. , vol.75 , pp. 655-680
    • Bhattacharyya, R.P.1
  • 19
    • 13444278821 scopus 로고    scopus 로고
    • Reconstruction of cellular signalling networks and analysis of their properties
    • Papin J.A., et al. Reconstruction of cellular signalling networks and analysis of their properties. Nat. Rev. Mol. Cell Biol. 2005, 6:99-111.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 99-111
    • Papin, J.A.1
  • 20
    • 1842507650 scopus 로고    scopus 로고
    • Axin: a master scaffold for multiple signaling pathways
    • Luo W., Lin S.-C. Axin: a master scaffold for multiple signaling pathways. Neurosignals 2004, 13:99-113.
    • (2004) Neurosignals , vol.13 , pp. 99-113
    • Luo, W.1    Lin, S.-C.2
  • 21
    • 35649013184 scopus 로고    scopus 로고
    • MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3β
    • Abell A.N., et al. MEKK4 stimulation of p38 and JNK activity is negatively regulated by GSK3β. J. Biol. Chem. 2007, 282:30476-30484.
    • (2007) J. Biol. Chem. , vol.282 , pp. 30476-30484
    • Abell, A.N.1
  • 22
    • 0037513408 scopus 로고    scopus 로고
    • A role of Dishevelled in relocating Axin to the plasma membrane during wingless signaling
    • Cliffe A., et al. A role of Dishevelled in relocating Axin to the plasma membrane during wingless signaling. Curr. Biol. 2003, 13:960-966.
    • (2003) Curr. Biol. , vol.13 , pp. 960-966
    • Cliffe, A.1
  • 23
    • 34250827150 scopus 로고    scopus 로고
    • Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
    • Bilic J., et al. Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation. Science 2007, 316:1619-1622.
    • (2007) Science , vol.316 , pp. 1619-1622
    • Bilic, J.1
  • 24
    • 0034947962 scopus 로고    scopus 로고
    • Axin facilitates Smad3 activation in the transforming growth factor β signaling pathway
    • Furuhashi M., et al. Axin facilitates Smad3 activation in the transforming growth factor β signaling pathway. Mol. Cell. Biol. 2001, 21:5132-5141.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 5132-5141
    • Furuhashi, M.1
  • 25
    • 42949092018 scopus 로고    scopus 로고
    • The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development
    • Schenck A., et al. The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development. Cell 2008, 133:486-497.
    • (2008) Cell , vol.133 , pp. 486-497
    • Schenck, A.1
  • 26
    • 78951483248 scopus 로고    scopus 로고
    • Early endosomal antigen 1 (EEA1) is an obligate scaffold for angiotensin ii-induced, PKC-α-dependent Akt activation in endosomes
    • Nazarewicz R.R., et al. Early endosomal antigen 1 (EEA1) is an obligate scaffold for angiotensin ii-induced, PKC-α-dependent Akt activation in endosomes. J. Biol. Chem. 2011, 286:2886-2895.
    • (2011) J. Biol. Chem. , vol.286 , pp. 2886-2895
    • Nazarewicz, R.R.1
  • 27
    • 80054835350 scopus 로고    scopus 로고
    • Hepatocyte growth factor-regulated tyrosine kinase substrate (Hgs) is involved in BMP signaling through phosphorylation of smads and TAK1 in early mouse embryo
    • Miura S., Mishina Y. Hepatocyte growth factor-regulated tyrosine kinase substrate (Hgs) is involved in BMP signaling through phosphorylation of smads and TAK1 in early mouse embryo. Dev. Dyn. 2011, 240:2474-2481.
    • (2011) Dev. Dyn. , vol.240 , pp. 2474-2481
    • Miura, S.1    Mishina, Y.2
  • 28
    • 0037223971 scopus 로고    scopus 로고
    • The evolution of signalling pathways in animal development
    • Pires-daSilva A., Sommer R.J. The evolution of signalling pathways in animal development. Nat. Rev. Genet. 2003, 4:39-49.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 39-49
    • Pires-daSilva, A.1    Sommer, R.J.2
  • 29
    • 0032869218 scopus 로고    scopus 로고
    • 1998 Warkany lecture: signaling pathways in development
    • Gerhart J. 1998 Warkany lecture: signaling pathways in development. Teratology 1999, 60:226-239.
    • (1999) Teratology , vol.60 , pp. 226-239
    • Gerhart, J.1
  • 30
    • 62849094483 scopus 로고    scopus 로고
    • Navigating the network: signaling cross-talk in hematopoietic cells
    • Fraser I.D.C., Germain R.N. Navigating the network: signaling cross-talk in hematopoietic cells. Nat. Immunol. 2009, 10:327-331.
    • (2009) Nat. Immunol. , vol.10 , pp. 327-331
    • Fraser, I.D.C.1    Germain, R.N.2
  • 31
    • 33744809296 scopus 로고    scopus 로고
    • A global analysis of cross-talk in a mammalian cellular signalling network
    • Natarajan M., et al. A global analysis of cross-talk in a mammalian cellular signalling network. Nat. Cell Biol. 2006, 8:571-580.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 571-580
    • Natarajan, M.1
  • 32
    • 36249018809 scopus 로고    scopus 로고
    • Cooperation of signalling pathways in embryonic mammary gland development
    • Robinson G.W. Cooperation of signalling pathways in embryonic mammary gland development. Nat. Rev. Genet. 2007, 8:963-972.
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 963-972
    • Robinson, G.W.1
  • 33
    • 34249725570 scopus 로고    scopus 로고
    • Predictive modeling of signaling crosstalk during C. elegans vulval development
    • Fisher J., et al. Predictive modeling of signaling crosstalk during C. elegans vulval development. PLoS Comput. Biol. 2007, 3:e92.
    • (2007) PLoS Comput. Biol. , vol.3
    • Fisher, J.1
  • 34
    • 32044451325 scopus 로고    scopus 로고
    • Cancer: a systems biology disease
    • Hornberg J.J., et al. Cancer: a systems biology disease. Biosystems 2006, 83:81-90.
    • (2006) Biosystems , vol.83 , pp. 81-90
    • Hornberg, J.J.1
  • 35
    • 33244464562 scopus 로고    scopus 로고
    • Critical nodes in signalling pathways: insights into insulin action
    • Taniguchi C.M., et al. Critical nodes in signalling pathways: insights into insulin action. Nat. Rev. Mol. Cell Biol. 2006, 7:85-96.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 85-96
    • Taniguchi, C.M.1
  • 36
    • 69749086899 scopus 로고    scopus 로고
    • Identification of rare cancer driver mutations by network reconstruction
    • Torkamani A., Schork N.J. Identification of rare cancer driver mutations by network reconstruction. Genome Res. 2009, 19:1570-1578.
    • (2009) Genome Res. , vol.19 , pp. 1570-1578
    • Torkamani, A.1    Schork, N.J.2
  • 37
    • 34447122100 scopus 로고    scopus 로고
    • A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK pathways
    • Kim D., et al. A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK pathways. Oncogene 2007, 26:4571-4579.
    • (2007) Oncogene , vol.26 , pp. 4571-4579
    • Kim, D.1
  • 38
    • 34548065794 scopus 로고    scopus 로고
    • How to design multi-target drugs: target search options in cellular networks
    • Korcsmáros T., et al. How to design multi-target drugs: target search options in cellular networks. Expert Opin. Drug Discov. 2007, 2:1-10.
    • (2007) Expert Opin. Drug Discov. , vol.2 , pp. 1-10
    • Korcsmáros, T.1
  • 39
    • 44249090908 scopus 로고    scopus 로고
    • Multipathway model enables prediction of kinase inhibitor cross-talk effects on migration of Her2-overexpressing mammary epithelial cells
    • Kumar N., et al. Multipathway model enables prediction of kinase inhibitor cross-talk effects on migration of Her2-overexpressing mammary epithelial cells. Mol. Pharmacol. 2008, 73:1668-1678.
    • (2008) Mol. Pharmacol. , vol.73 , pp. 1668-1678
    • Kumar, N.1
  • 40
    • 77955444349 scopus 로고    scopus 로고
    • Uniformly curated signaling pathways reveal tissue-specific cross-talks and support drug target discovery
    • Korcsmáros T., et al. Uniformly curated signaling pathways reveal tissue-specific cross-talks and support drug target discovery. Bioinformatics 2010, 26:2042-2050.
    • (2010) Bioinformatics , vol.26 , pp. 2042-2050
    • Korcsmáros, T.1
  • 41
    • 77955802924 scopus 로고    scopus 로고
    • Ultrasensitive responses and specificity in cell signaling
    • Haney S., et al. Ultrasensitive responses and specificity in cell signaling. BMC Syst. Biol. 2010, 4:119.
    • (2010) BMC Syst. Biol. , vol.4 , pp. 119
    • Haney, S.1
  • 42
    • 28444439900 scopus 로고    scopus 로고
    • Organelle identity and the signposts for membrane traffic
    • Behnia R., Munro S. Organelle identity and the signposts for membrane traffic. Nature 2005, 438:597-604.
    • (2005) Nature , vol.438 , pp. 597-604
    • Behnia, R.1    Munro, S.2
  • 43
    • 77954983113 scopus 로고    scopus 로고
    • Appl1 is essential for the survival of Xenopus pancreas, duodenum, and stomach progenitor cells
    • Wen L., et al. Appl1 is essential for the survival of Xenopus pancreas, duodenum, and stomach progenitor cells. Dev. Dyn. 2010, 239:2198-2207.
    • (2010) Dev. Dyn. , vol.239 , pp. 2198-2207
    • Wen, L.1
  • 44
    • 78650795768 scopus 로고    scopus 로고
    • APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway
    • Xin X., et al. APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway. Am. J. Physiol. Endocrinol. Metab. 2011, 300:E103-E110.
    • (2011) Am. J. Physiol. Endocrinol. Metab. , vol.300
    • Xin, X.1
  • 45
    • 27744577296 scopus 로고    scopus 로고
    • TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
    • Shim J.-H., et al. TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo. Genes Dev. 2005, 19:2668-2681.
    • (2005) Genes Dev. , vol.19 , pp. 2668-2681
    • Shim, J.-H.1
  • 46
    • 58149193222 scopus 로고    scopus 로고
    • Human Protein Reference Database - 2009 update
    • Prasad T.S.K., et al. Human Protein Reference Database - 2009 update. Nucleic Acids Res. 2009, 37:D767-D772.
    • (2009) Nucleic Acids Res. , vol.37
    • Prasad, T.S.K.1
  • 47
    • 84859699831 scopus 로고    scopus 로고
    • The Gene Ontology: enhancements for 2011
    • The Gene Ontology Consortium
    • The Gene Ontology Consortium The Gene Ontology: enhancements for 2011. Nucleic Acids Res. 2012, 40:D559-D564.
    • (2012) Nucleic Acids Res. , vol.40
  • 48
    • 78651328883 scopus 로고    scopus 로고
    • The BioGRID Interaction Database: 2011 update
    • Stark C., et al. The BioGRID Interaction Database: 2011 update. Nucleic Acids Res. 2011, 39:D698-D704.
    • (2011) Nucleic Acids Res. , vol.39
    • Stark, C.1
  • 49
    • 78651324347 scopus 로고    scopus 로고
    • The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
    • Szklarczyk D., et al. The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored. Nucleic Acids Res. 2011, 39:D561-D568.
    • (2011) Nucleic Acids Res. , vol.39
    • Szklarczyk, D.1
  • 50
    • 25144498379 scopus 로고    scopus 로고
    • A human protein-protein interaction network: a resource for annotating the proteome
    • Stelzl U., et al. A human protein-protein interaction network: a resource for annotating the proteome. Cell 2005, 122:957-968.
    • (2005) Cell , vol.122 , pp. 957-968
    • Stelzl, U.1
  • 51
    • 0033607141 scopus 로고    scopus 로고
    • Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the β1-adrenergic receptor
    • Tang Y., et al. Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the β1-adrenergic receptor. Proc. Natl Acad. Sci. U.S.A. 1999, 96:12559-12564.
    • (1999) Proc. Natl Acad. Sci. U.S.A. , vol.96 , pp. 12559-12564
    • Tang, Y.1
  • 52
    • 0037075547 scopus 로고    scopus 로고
    • Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors
    • Soubeyran P., et al. Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors. Nature 2002, 416:183-187.
    • (2002) Nature , vol.416 , pp. 183-187
    • Soubeyran, P.1
  • 53
    • 0842307321 scopus 로고    scopus 로고
    • Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein
    • Yam J.W.P., et al. Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein. Blood 2004, 103:1445-1453.
    • (2004) Blood , vol.103 , pp. 1445-1453
    • Yam, J.W.P.1
  • 54
    • 3543143101 scopus 로고    scopus 로고
    • Functional proteomics mapping of a human signaling pathway
    • Colland F., et al. Functional proteomics mapping of a human signaling pathway. Genome Res. 2004, 7:1324-1332.
    • (2004) Genome Res. , vol.7 , pp. 1324-1332
    • Colland, F.1
  • 55
    • 79951855236 scopus 로고    scopus 로고
    • Compartmentalized CDK2 is connected with SHP-1 and β-catenin and regulates insulin internalization
    • Fiset A., et al. Compartmentalized CDK2 is connected with SHP-1 and β-catenin and regulates insulin internalization. Cell. Signal. 2011, 23:911-919.
    • (2011) Cell. Signal. , vol.23 , pp. 911-919
    • Fiset, A.1
  • 56
    • 67650540827 scopus 로고    scopus 로고
    • Endosomal adaptor proteins APPL1 and APPL2 are novel activators of β-catenin/TCF-mediated transcription
    • Rashid S., et al. Endosomal adaptor proteins APPL1 and APPL2 are novel activators of β-catenin/TCF-mediated transcription. J. Biol. Chem. 2009, 284:18115-18128.
    • (2009) J. Biol. Chem. , vol.284 , pp. 18115-18128
    • Rashid, S.1
  • 57
    • 77950553992 scopus 로고    scopus 로고
    • Smad3 prevents β-catenin degradation and facilitates β-catenin nuclear translocation in chondrocytes
    • Zhang M., et al. Smad3 prevents β-catenin degradation and facilitates β-catenin nuclear translocation in chondrocytes. J. Biol. Chem. 2010, 285:8703-8710.
    • (2010) J. Biol. Chem. , vol.285 , pp. 8703-8710
    • Zhang, M.1
  • 58
    • 77952903562 scopus 로고    scopus 로고
    • Signalling ballet in space and time
    • Kholodenko B.N., et al. Signalling ballet in space and time. Nat. Rev. Mol. Cell Biol. 2010, 11:414-426.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 414-426
    • Kholodenko, B.N.1
  • 59
    • 40849100220 scopus 로고    scopus 로고
    • Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics
    • Bashor C.J., et al. Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics. Science 2008, 319:1539-1543.
    • (2008) Science , vol.319 , pp. 1539-1543
    • Bashor, C.J.1
  • 60
    • 77952944052 scopus 로고    scopus 로고
    • Designing customized cell signalling circuits
    • Lim W.A. Designing customized cell signalling circuits. Nat. Rev. Mol. Cell Biol. 2010, 11:393-403.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 393-403
    • Lim, W.A.1
  • 61
    • 62849097694 scopus 로고    scopus 로고
    • New roles for endosomes: from vesicular carriers to multi-purpose platforms
    • Gould G.W., Lippincott-Schwartz J. New roles for endosomes: from vesicular carriers to multi-purpose platforms. Nat. Rev. Mol. Cell Biol. 2009, 10:287-292.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 287-292
    • Gould, G.W.1    Lippincott-Schwartz, J.2
  • 62
    • 0036787904 scopus 로고    scopus 로고
    • Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival
    • Wang Y., et al. Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival. Mol. Cell. Biol. 2002, 22:7279-7290.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 7279-7290
    • Wang, Y.1
  • 63
    • 70449552889 scopus 로고    scopus 로고
    • Endosomes: a legitimate platform for the signaling train
    • Murphy J.E., et al. Endosomes: a legitimate platform for the signaling train. Proc. Natl Acad. Sci. U.S.A. 2009, 106:17615-17622.
    • (2009) Proc. Natl Acad. Sci. U.S.A. , vol.106 , pp. 17615-17622
    • Murphy, J.E.1
  • 64
    • 84860428078 scopus 로고    scopus 로고
    • Endocytic trafficking of neurotrophins in neural development
    • Ascano M., et al. Endocytic trafficking of neurotrophins in neural development. Trends Cell Biol. 2012, 22:266-273.
    • (2012) Trends Cell Biol. , vol.22 , pp. 266-273
    • Ascano, M.1
  • 65
    • 47749089820 scopus 로고    scopus 로고
    • Regulation of TNFR1 and CD95 signalling by receptor compartmentalization
    • Schütze S., et al. Regulation of TNFR1 and CD95 signalling by receptor compartmentalization. Nat. Rev. Mol. Cell Biol. 2008, 9:655-662.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 655-662
    • Schütze, S.1
  • 66
    • 79960081111 scopus 로고    scopus 로고
    • The STAT3 beacon: IL-6 recurrently activates STAT 3 from endosomal structures
    • German C.L., et al. The STAT3 beacon: IL-6 recurrently activates STAT 3 from endosomal structures. Exp. Cell Res. 2011, 317:1955-1969.
    • (2011) Exp. Cell Res. , vol.317 , pp. 1955-1969
    • German, C.L.1
  • 67
    • 35048878660 scopus 로고    scopus 로고
    • Live cell imaging of interleukin-6-induced targeting of " transcription factor" STAT3 to sequestering endosomes in the cytoplasm
    • Xu F., et al. Live cell imaging of interleukin-6-induced targeting of " transcription factor" STAT3 to sequestering endosomes in the cytoplasm. Am. J Physiol. Cell Physiol. 2007, 293:C1374-C1382.
    • (2007) Am. J Physiol. Cell Physiol. , vol.293
    • Xu, F.1
  • 68
    • 84872212844 scopus 로고    scopus 로고
    • Spatiotemporal regulation of MyD88 - IRF-7 signalling for robust type-I interferon induction
    • Ohba Y., et al. Spatiotemporal regulation of MyD88 - IRF-7 signalling for robust type-I interferon induction. Nature 2005, 2:1-6.
    • (2005) Nature , vol.2 , pp. 1-6
    • Ohba, Y.1
  • 69
    • 51649130231 scopus 로고    scopus 로고
    • Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation
    • Kermorgant S., Parker P.J. Receptor trafficking controls weak signal delivery: a strategy used by c-Met for STAT3 nuclear accumulation. J. Cell Biol. 2008, 182:855-863.
    • (2008) J. Cell Biol. , vol.182 , pp. 855-863
    • Kermorgant, S.1    Parker, P.J.2
  • 70
    • 77952382637 scopus 로고    scopus 로고
    • Endocytic pathway is required for Drosophila Toll innate immune signaling
    • Huang H.-R., et al. Endocytic pathway is required for Drosophila Toll innate immune signaling. Proc. Natl Acad. Sci. U.S.A. 2010, 107:8322-8327.
    • (2010) Proc. Natl Acad. Sci. U.S.A. , vol.107 , pp. 8322-8327
    • Huang, H.-R.1
  • 71
    • 35649018124 scopus 로고    scopus 로고
    • The endocytic control of JAK/STAT signalling in Drosophila
    • Devergne O., et al. The endocytic control of JAK/STAT signalling in Drosophila. J. Cell Sci. 2007, 120:3457-3464.
    • (2007) J. Cell Sci. , vol.120 , pp. 3457-3464
    • Devergne, O.1
  • 72
    • 78049363486 scopus 로고    scopus 로고
    • Negative regulation of Drosophila JAK-STAT signalling by endocytic trafficking
    • Vidal O.M., et al. Negative regulation of Drosophila JAK-STAT signalling by endocytic trafficking. J. Cell Sci. 2010, 123:3457-3466.
    • (2010) J. Cell Sci. , vol.123 , pp. 3457-3466
    • Vidal, O.M.1
  • 73
    • 33846109356 scopus 로고    scopus 로고
    • A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14
    • Bohn G., et al. A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14. Nat. Med. 2007, 13:38-45.
    • (2007) Nat. Med. , vol.13 , pp. 38-45
    • Bohn, G.1
  • 74
    • 34547750315 scopus 로고    scopus 로고
    • Endosomal transport of neurotrophins: roles in signaling and neurodegenerative diseases
    • Bronfman F.C., et al. Endosomal transport of neurotrophins: roles in signaling and neurodegenerative diseases. Dev. Neurobiol. 2007, 67:1183-1203.
    • (2007) Dev. Neurobiol. , vol.67 , pp. 1183-1203
    • Bronfman, F.C.1
  • 75
    • 56149094041 scopus 로고    scopus 로고
    • Endocytosis and cancer: an " insider" network with dangerous liaisons
    • Lanzetti L., Di Fiore P.P. Endocytosis and cancer: an " insider" network with dangerous liaisons. Traffic 2008, 9:2011-2021.
    • (2008) Traffic , vol.9 , pp. 2011-2021
    • Lanzetti, L.1    Di Fiore, P.P.2
  • 76
    • 0032797695 scopus 로고    scopus 로고
    • Differential expression of RAB5A in human lung adenocarcinoma cells with different metastasis potential
    • Yu L., et al. Differential expression of RAB5A in human lung adenocarcinoma cells with different metastasis potential. Clin. Exp. Metastasis 1999, 17:213-219.
    • (1999) Clin. Exp. Metastasis , vol.17 , pp. 213-219
    • Yu, L.1
  • 77
    • 34548649469 scopus 로고    scopus 로고
    • Expression of Rab5a in hepatocellular carcinoma: possible involvement in epidermal growth factor signaling
    • Fukui K., et al. Expression of Rab5a in hepatocellular carcinoma: possible involvement in epidermal growth factor signaling. Hepatol. Res. 2007, 37:957-965.
    • (2007) Hepatol. Res. , vol.37 , pp. 957-965
    • Fukui, K.1
  • 78
    • 44449127738 scopus 로고    scopus 로고
    • Endosomal sorting complex required for transport proteins in cancer pathogenesis, vesicular transport, and non-endosomal functions
    • Tanaka N., et al. Endosomal sorting complex required for transport proteins in cancer pathogenesis, vesicular transport, and non-endosomal functions. Cancer Sci. 2008, 99:1293-1303.
    • (2008) Cancer Sci. , vol.99 , pp. 1293-1303
    • Tanaka, N.1
  • 79
    • 34547114456 scopus 로고    scopus 로고
    • Pathways of clathrin-independent endocytosis
    • Mayor S., Pagano R.E. Pathways of clathrin-independent endocytosis. Nat. Rev. Mol. Cell Biol. 2007, 8:603-612.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 603-612
    • Mayor, S.1    Pagano, R.E.2
  • 80
    • 38549092474 scopus 로고    scopus 로고
    • Membrane recognition by phospholipid-binding domains
    • Lemmon M.A. Membrane recognition by phospholipid-binding domains. Nat. Rev. Mol. Cell Biol. 2008, 9:99-111.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 99-111
    • Lemmon, M.A.1
  • 81
    • 30944461203 scopus 로고    scopus 로고
    • Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions
    • Michell R.H., et al. Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions. Trends Biochem. Sci. 2006, 31:52-63.
    • (2006) Trends Biochem. Sci. , vol.31 , pp. 52-63
    • Michell, R.H.1
  • 82
    • 72549101543 scopus 로고    scopus 로고
    • Finding scaffold proteins in interactomes
    • Ramírez F., Albrecht M. Finding scaffold proteins in interactomes. Trends Cell Biol. 2010, 20:2-4.
    • (2010) Trends Cell Biol. , vol.20 , pp. 2-4
    • Ramírez, F.1    Albrecht, M.2
  • 83
    • 84858077472 scopus 로고    scopus 로고
    • The Pfam protein families database
    • Punta M., et al. The Pfam protein families database. Nucleic Acids Res. 2012, 40:D290-D301.
    • (2012) Nucleic Acids Res. , vol.40
    • Punta, M.1
  • 84
    • 84862192725 scopus 로고    scopus 로고
    • The UniProt-GO Annotation database in 2011
    • Dimmer E.C., et al. The UniProt-GO Annotation database in 2011. Nucleic Acids Res. 2012, 40:D565-D570.
    • (2012) Nucleic Acids Res. , vol.40
    • Dimmer, E.C.1
  • 85
    • 84860439064 scopus 로고    scopus 로고
    • Linking proteins to signaling pathways for experiment design and evaluation
    • Farkas I.J., et al. Linking proteins to signaling pathways for experiment design and evaluation. PLoS ONE 2012, 7:e36202.
    • (2012) PLoS ONE , vol.7
    • Farkas, I.J.1
  • 86
    • 84858983547 scopus 로고    scopus 로고
    • KEGG for integration and interpretation of large-scale molecular data sets
    • Kanehisa M., et al. KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res. 2012, 40:D109-D114.
    • (2012) Nucleic Acids Res. , vol.40
    • Kanehisa, M.1
  • 87
    • 78651275182 scopus 로고    scopus 로고
    • Reactome: a database of reactions, pathways and biological processes
    • Croft D., et al. Reactome: a database of reactions, pathways and biological processes. Nucleic Acids Res. 2011, 39:D691-D697.
    • (2011) Nucleic Acids Res. , vol.39
    • Croft, D.1
  • 88


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