Determination of progesterone and some of its neuroactive ring A-reduced metabolites in human serum

Journal of Steroid Biochemistry and Molecular Biology

Volumn 74, Issue 3, 2000, Pages 137-142

  Pearson Murphy, Beverley E ^a,b,c   Allison, Cyndie M ^b  

^a MCGILL UNIVERSITY   (Canada)

^b Allan Memorial Institute   (Canada)

^c MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

High performance liquid chromatography (HPLC); Neuroactive steroids; Pregnanedione; Pregnanolone; Pregnenolone; Progesterone; Progesterone metabolites; Radioimmunoassay

Indexed keywords

5ALPHA PREGNANE 3,20 DIONE; ELTANOLONE; PREGNANEDIONE; PREGNENOLONE; PROGESTERONE; TETRAHYDROPROGESTERONE;

ADULT; ARTICLE; CROSS REACTION; FEMALE; FOLLICULAR PHASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE BLOOD LEVEL; HORMONE DETERMINATION; HUMAN; MALE; MENSTRUAL CYCLE; NORMAL HUMAN; PREGNANCY;

ADOLESCENT; ADULT; ANTIBODY SPECIFICITY; BINDING, COMPETITIVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROSS REACTIONS; FEMALE; HUMANS; IMMUNE SERA; MALE; MENSTRUAL CYCLE; MIDDLE AGED; PREGNANCY; PREGNANEDIONES; PREGNANOLONE; PROGESTERONE; RADIOIMMUNOASSAY; REFERENCE STANDARDS; SOLVENTS;

EID: 0033736883     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(00)00098-4     Document Type: Article

References (25)

1. Correlations between the chemical structures and the pharmacological actions of the steroids
2. Central activity and structure in a series of water-soluble steroids
3. Progesterone and 5α-pregnane-3,20-dione in peripheral blood of normal young women. Daily measurements throughout the menstrual cycle
4. The human corpus luteum secretes 5α-pregnane-3,20-dione
5. Hormone production during pregnancy in the primigravid patient
6. Serum concentrations of progesterone and 5α-dihydroprogesterone during labor and early postpartum
7. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor
8. Circulating levels of anxiolytic steroids in the luteal phase in women with premenstrual syndrome and in control subjects
9. Relationship between symptom severity and steroid variation in women with premenstrual syndrome: Study on serum pregnenolone, pregnenolone sulfate, 5α-pregnane-3,20-dione and 3α-hydroxy-5α-pregnane-20-one
10. Circulating levels of allopregnanolone in humans: Gender, age, and endocrine influences
11. High performance liquid chromatography of the reduction products of progesterone
12. Competitive binding to multiple stereospecific binding agents as a means of verifying the identity of a ligand. Application to cortisol in human umbilical cord blood
13. Metabolism of progesterone by human lymphocytes: Production of neuroactive steroids
14. The conversion of progesterone into 5 alpha-pregnane-3,20-dione, 3 beta-hydroxy-5 alpha-pregnan-20-one, and its fatty acid esters by preparations of bovine corpora lutea
15. Radioimmunoassay of 3-α-hydroxy-5-α-pregnan-20-one in rat and human plasma
16. Studies on the pattern of circulating steroids in the normal menstrual cycle. 3. Circadian variation in the peri-ovulatory period
17. Seventy-two hour infusions of LHRH in normal men: Gonadotropin and testicular steroid responses
18. Dexamethasone suppressibility of plasma prenenolone (3β-hydroxy-5-pregnen-20-one) in normal men
19. Plasma pregnenolone and 17-ON-pregnenolone in patients with adrenal tumors, ACTH excess, or idiopathic hirsutism
20. Response of the pituitary-adrenal axis to hypoglycemic stress in women with polycystic ovary syndrome
21. Contrasting effects of 5α- and 5β-pregnane-3,20-dione on the motor activity of ovariectomized rats
22. Determination of some neuroactive progesterone metabolites in pregnancy
23. Conversion of progesterone to 5β-pregnane-3,20-dione by brain tissue