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Volumn 3, Issue 11, 2008, Pages

Progestin receptor-mediated reduction of anxiety-like behavior in male rats

Author keywords

[No Author keywords available]

Indexed keywords

MIFEPRISTONE; PROGESTERONE; PROGESTERONE RECEPTOR; TESTOSTERONE;

EID: 56749158610     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003606     Document Type: Article
Times cited : (29)

References (60)
  • 1
    • 0029056668 scopus 로고
    • Anti-anxiety effects of progesterone and some of its reduced metabolites: An evaluation using the burying behavior test
    • Picazo O, Fernandez-Guasti A (1995) Anti-anxiety effects of progesterone and some of its reduced metabolites: an evaluation using the burying behavior test. Brain Res 680: 135-141.
    • (1995) Brain Res , vol.680 , pp. 135-141
    • Picazo, O.1    Fernandez-Guasti, A.2
  • 2
    • 0025918687 scopus 로고
    • Anxiolytic effects of 3 alpha-hydroxy-5 alpha[beta]-pregnan-20-one: Endogenous metabolites of progesterone that are active at the GABAA receptor
    • Bitran D, Hilvers RJ, Kellogg CK (1991) Anxiolytic effects of 3 alpha-hydroxy-5 alpha[beta]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor. Brain Res 561: 157-161.
    • (1991) Brain Res , vol.561 , pp. 157-161
    • Bitran, D.1    Hilvers, R.J.2    Kellogg, C.K.3
  • 3
    • 0030266388 scopus 로고    scopus 로고
    • Effects of the estrous cycle and ovarian hormones on behavioral indices of anxiety in female rats
    • Mora S, Dussaubat N, Diaz-Veliz G (1996) Effects of the estrous cycle and ovarian hormones on behavioral indices of anxiety in female rats. Psychoneuroendocrinology 21: 609-620.
    • (1996) Psychoneuroendocrinology , vol.21 , pp. 609-620
    • Mora, S.1    Dussaubat, N.2    Diaz-Veliz, G.3
  • 4
    • 0034490999 scopus 로고    scopus 로고
    • Estrous cycle and sex differences in performance on anxiety tasks coincide with increases in hippocampal progesterone and 3alpha,5alpha-THP
    • Frye CA, Petralia SM, Rhodes ME (2000) Estrous cycle and sex differences in performance on anxiety tasks coincide with increases in hippocampal progesterone and 3alpha,5alpha-THP. Pharmacol Biochem Behav 67: 587-596.
    • (2000) Pharmacol Biochem Behav , vol.67 , pp. 587-596
    • Frye, C.A.1    Petralia, S.M.2    Rhodes, M.E.3
  • 6
    • 8544258089 scopus 로고    scopus 로고
    • Progesterone attenuates corticotropin-releasing factor-enhanced but not fear-potentiated startle via the activity of its neuroactive metabolite, allopregnanolone
    • Toufexis DJ, Davis C, Hammond A, Davis M (2004) Progesterone attenuates corticotropin-releasing factor-enhanced but not fear-potentiated startle via the activity of its neuroactive metabolite, allopregnanolone. J Neurosci 24: 10280-10287.
    • (2004) J Neurosci , vol.24 , pp. 10280-10287
    • Toufexis, D.J.1    Davis, C.2    Hammond, A.3    Davis, M.4
  • 7
    • 0028283503 scopus 로고
    • Molecular mechanisms of action of steroid/ thyroid receptor superfamily members
    • Tsai MJ, O'Malley BW (1994) Molecular mechanisms of action of steroid/ thyroid receptor superfamily members. Annu Rev Biochem. pp 63451-63468.
    • (1994) Annu Rev Biochem , pp. 63451-63468
    • Tsai, M.J.1    O'Malley, B.W.2
  • 8
    • 0031170877 scopus 로고    scopus 로고
    • Progesterone receptor function from a behavioral perspective
    • Mani SK, Blaustein JD, O'Malley BW (1997) Progesterone receptor function from a behavioral perspective. Horm Behav 31: 244-255.
    • (1997) Horm Behav , vol.31 , pp. 244-255
    • Mani, S.K.1    Blaustein, J.D.2    O'Malley, B.W.3
  • 9
    • 4444284496 scopus 로고    scopus 로고
    • Reproductive tissue selective actions of progesterone receptors
    • Mulac-Jericevic B, Conneely OM (2004) Reproductive tissue selective actions of progesterone receptors. Reproduction 128: 139-146.
    • (2004) Reproduction , vol.128 , pp. 139-146
    • Mulac-Jericevic, B.1    Conneely, O.M.2
  • 11
    • 0036133869 scopus 로고    scopus 로고
    • Neurosteroids: Biochemistry and clinical significance
    • Mellon SH, Griffin LD (2002) Neurosteroids: biochemistry and clinical significance. Trends Endocrinol Metab 13: 35-43.
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 35-43
    • Mellon, S.H.1    Griffin, L.D.2
  • 12
    • 0003106545 scopus 로고    scopus 로고
    • Neurosteroids: From Definition and Biochemistry to Physiopathologic Function
    • Baulieu EE, Robel P, Schumacher M, eds, New Jersey: Humana Press Inc. pp
    • Robel P, Schumacher M, Baulieu EE (1999) Neurosteroids: From Definition and Biochemistry to Physiopathologic Function. In: Baulieu EE, Robel P, Schumacher M, eds. Neurosteroids: A new regulatory function in the nervous system. New Jersey: Humana Press Inc. pp 1-25.
    • (1999) Neurosteroids: A new regulatory function in the nervous system , pp. 1-25
    • Robel, P.1    Schumacher, M.2    Baulieu, E.E.3
  • 13
    • 0026579057 scopus 로고
    • Neuroactive steroids
    • Paul SM, Purdy RH (1992) Neuroactive steroids. FASEB J 6: 2311-2322.
    • (1992) FASEB J , vol.6 , pp. 2311-2322
    • Paul, S.M.1    Purdy, R.H.2
  • 14
    • 0037293399 scopus 로고    scopus 로고
    • Neuroactive steroids: Mechanisms of action and neuropsychopharmacological properties
    • Rupprecht R (2003) Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties. Psychoneuroendocrinology 28: 139-168.
    • (2003) Psychoneuroendocrinology , vol.28 , pp. 139-168
    • Rupprecht, R.1
  • 15
    • 0025987983 scopus 로고
    • Anxiolytic activity of the progesterone metabolite 5 alpha-pregnan-3 alpha-o1-20-one
    • Wieland S, Lan NC, Mirasedeghi S, Gee KW (1991) Anxiolytic activity of the progesterone metabolite 5 alpha-pregnan-3 alpha-o1-20-one. Brain Res 565: 263-268.
    • (1991) Brain Res , vol.565 , pp. 263-268
    • Wieland, S.1    Lan, N.C.2    Mirasedeghi, S.3    Gee, K.W.4
  • 16
    • 0028916048 scopus 로고
    • Anxiolytic effect of progesterone is mediated by the neurosteroid allopregnanolone at brain GABAA receptors
    • Bitran D, Shiekh M, McLeod M (1995) Anxiolytic effect of progesterone is mediated by the neurosteroid allopregnanolone at brain GABAA receptors. J Neuroendocrinol 7: 171-177.
    • (1995) J Neuroendocrinol , vol.7 , pp. 171-177
    • Bitran, D.1    Shiekh, M.2    McLeod, M.3
  • 17
    • 0029123415 scopus 로고
    • Infusions of diazepam and allopregnanolone into the midbrain central gray facilitate open-field behavior and sexual receptivity in female rats
    • McCarthy MM, Felzenberg E, Robbins A, Pfaff DW, Schwartz-Giblin S (1995) Infusions of diazepam and allopregnanolone into the midbrain central gray facilitate open-field behavior and sexual receptivity in female rats. Horm Behav 29: 279-295.
    • (1995) Horm Behav , vol.29 , pp. 279-295
    • McCarthy, M.M.1    Felzenberg, E.2    Robbins, A.3    Pfaff, D.W.4    Schwartz-Giblin, S.5
  • 18
    • 11144284666 scopus 로고    scopus 로고
    • Anxiolytic activity of progesterone in progesterone receptor knockout mice
    • Reddy DS, O'Malley BW, Rogawski MA (2005) Anxiolytic activity of progesterone in progesterone receptor knockout mice. Neuropharmacology 48: 14-24.
    • (2005) Neuropharmacology , vol.48 , pp. 14-24
    • Reddy, D.S.1    O'Malley, B.W.2    Rogawski, M.A.3
  • 19
    • 24944582910 scopus 로고    scopus 로고
    • Enhanced sexual behaviors and androgen receptor immunoreactivity in the male progesterone receptor knockout mouse
    • Schneider JS, Burgess C, Sleiter NC, Doncarlos LL, Lydon JP, et al. (2005) Enhanced sexual behaviors and androgen receptor immunoreactivity in the male progesterone receptor knockout mouse. Endocrinology 146: 4340-4348.
    • (2005) Endocrinology , vol.146 , pp. 4340-4348
    • Schneider, J.S.1    Burgess, C.2    Sleiter, N.C.3    Doncarlos, L.L.4    Lydon, J.P.5
  • 20
    • 1642345295 scopus 로고    scopus 로고
    • Progesterone enhances motor, anxiolytic, analgesic, and antidepressive behavior of wild-type mice, but not those deficient in type 1 5 alpha-reductase
    • Frye CA, Walf AA, Rhodes ME, Harney JP (2004) Progesterone enhances motor, anxiolytic, analgesic, and antidepressive behavior of wild-type mice, but not those deficient in type 1 5 alpha-reductase. Brain Res 1004: 116-124.
    • (2004) Brain Res , vol.1004 , pp. 116-124
    • Frye, C.A.1    Walf, A.A.2    Rhodes, M.E.3    Harney, J.P.4
  • 21
    • 0033053545 scopus 로고    scopus 로고
    • Reduced progesterone metabolites are not critical for plus-maze performance of lactating female rats
    • Kellogg CK, Barrett KA (1999) Reduced progesterone metabolites are not critical for plus-maze performance of lactating female rats. Pharmacol Biochem Behav 63: 441-448.
    • (1999) Pharmacol Biochem Behav , vol.63 , pp. 441-448
    • Kellogg, C.K.1    Barrett, K.A.2
  • 22
    • 0022374863 scopus 로고
    • Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat
    • Pellow S, Chopin P, File SE, Briley M (1985) Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods 14: 149-167.
    • (1985) J Neurosci Methods , vol.14 , pp. 149-167
    • Pellow, S.1    Chopin, P.2    File, S.E.3    Briley, M.4
  • 23
    • 34347207241 scopus 로고    scopus 로고
    • The use of the elevated plus maze as an assay of anxiety-related behavior in rodents
    • Walf AA, Frye CA (2007) The use of the elevated plus maze as an assay of anxiety-related behavior in rodents. Nat Protoc 2: 322-328.
    • (2007) Nat Protoc , vol.2 , pp. 322-328
    • Walf, A.A.1    Frye, C.A.2
  • 24
    • 0014764526 scopus 로고
    • Effect of medroxyprogesterone acetate (Provera) on the metabolism and biological activity of testosterone
    • Gordon GG, Southren AL, Tochimoto S, Olivo J, Altman K, et al. (1970) Effect of medroxyprogesterone acetate (Provera) on the metabolism and biological activity of testosterone. J Clin Endocrinol Metab 30: 449-456.
    • (1970) J Clin Endocrinol Metab , vol.30 , pp. 449-456
    • Gordon, G.G.1    Southren, A.L.2    Tochimoto, S.3    Olivo, J.4    Altman, K.5
  • 25
    • 0018193850 scopus 로고
    • A direct effect of medroxyprogesterone acetate on 17 beta-hydroxysteroid dehydrogenase in adult rat testis
    • Satyaswaroop PG, Gurpide E (1978) A direct effect of medroxyprogesterone acetate on 17 beta-hydroxysteroid dehydrogenase in adult rat testis. Endocrinology 102: 1761-1765.
    • (1978) Endocrinology , vol.102 , pp. 1761-1765
    • Satyaswaroop, P.G.1    Gurpide, E.2
  • 26
    • 0018973042 scopus 로고
    • Direct effects of medroxyprogesterone acetate (MPA) and megestrol acetate (MGA) on rat testicular steroidogenesis
    • Barbieri RL, Ryan KJ (1980) Direct effects of medroxyprogesterone acetate (MPA) and megestrol acetate (MGA) on rat testicular steroidogenesis. Acta Endocrinol (Copenh) 94: 419-425.
    • (1980) Acta Endocrinol (Copenh) , vol.94 , pp. 419-425
    • Barbieri, R.L.1    Ryan, K.J.2
  • 27
    • 0023870959 scopus 로고
    • Effects of medroxyprogesterone acetate on plasma testosterone and sexual behavior in male cynomolgus monkeys (Macaca fascicularis)
    • Zumpe D, Michael RP (1988) Effects of medroxyprogesterone acetate on plasma testosterone and sexual behavior in male cynomolgus monkeys (Macaca fascicularis). Physiol Behav 42: 343-349.
    • (1988) Physiol Behav , vol.42 , pp. 343-349
    • Zumpe, D.1    Michael, R.P.2
  • 28
    • 0021265307 scopus 로고
    • Inhibition of sexual behavior in female guinea pigs by a progestin receptor antagonist
    • Brown TJ, Blaustein JD (1984) Inhibition of sexual behavior in female guinea pigs by a progestin receptor antagonist. Brain Res 301: 343-349.
    • (1984) Brain Res , vol.301 , pp. 343-349
    • Brown, T.J.1    Blaustein, J.D.2
  • 29
    • 0022516699 scopus 로고
    • Abbreviation of the period of sexual behavior in female guinea pigs by the progesterone antagonist RU 486
    • Brown TJ, Blaustein JD (1986) Abbreviation of the period of sexual behavior in female guinea pigs by the progesterone antagonist RU 486. Brain Res 373: 103-113.
    • (1986) Brain Res , vol.373 , pp. 103-113
    • Brown, T.J.1    Blaustein, J.D.2
  • 30
    • 3042679244 scopus 로고    scopus 로고
    • Different stress modalities result in distinct steroid hormone responses by male rats
    • Andersen ML, Bignotto M, Machado RB, Tufik S (2004) Different stress modalities result in distinct steroid hormone responses by male rats. Braz J Med Biol Res 37: 791-797.
    • (2004) Braz J Med Biol Res , vol.37 , pp. 791-797
    • Andersen, M.L.1    Bignotto, M.2    Machado, R.B.3    Tufik, S.4
  • 31
    • 31144476935 scopus 로고    scopus 로고
    • Microarray profiling of gene expression patterns in adult male rat brain following acute progesterone treatment
    • Auger CJ, Jessen HJ, Auger AP (2006) Microarray profiling of gene expression patterns in adult male rat brain following acute progesterone treatment. Brain Res 1067: 58-66.
    • (2006) Brain Res , vol.1067 , pp. 58-66
    • Auger, C.J.1    Jessen, H.J.2    Auger, A.P.3
  • 32
    • 0015325732 scopus 로고
    • Individual differences in sexual responsiveness to estrogen and progesterone in ovariectomized rats
    • Powers JB, Valenstein ES (1972) Individual differences in sexual responsiveness to estrogen and progesterone in ovariectomized rats. Physiol Behav 8: 673-676.
    • (1972) Physiol Behav , vol.8 , pp. 673-676
    • Powers, J.B.1    Valenstein, E.S.2
  • 33
    • 0017642430 scopus 로고
    • Sequential inhibition of sexual behavior by progesterone in female rats: Comparison with a synthetic antiestrogen
    • Blaustein JD, Wade GN (1977) Sequential inhibition of sexual behavior by progesterone in female rats: comparison with a synthetic antiestrogen. J Comp Physiol Psychol 91: 752-760.
    • (1977) J Comp Physiol Psychol , vol.91 , pp. 752-760
    • Blaustein, J.D.1    Wade, G.N.2
  • 34
    • 0017746428 scopus 로고
    • Circadian periodicities of serum androgens, progesterone, gonadotropins and luteinizing hormone-releasing hormone in male rats: The effects of hypothalamic deafferentation, castration and adrenalectomy
    • Kalra PS, Kalra SP (1977) Circadian periodicities of serum androgens, progesterone, gonadotropins and luteinizing hormone-releasing hormone in male rats: the effects of hypothalamic deafferentation, castration and adrenalectomy. Endocrinology 101: 1821-1827.
    • (1977) Endocrinology , vol.101 , pp. 1821-1827
    • Kalra, P.S.1    Kalra, S.P.2
  • 35
    • 0035032992 scopus 로고    scopus 로고
    • Corticosteroids in relation to fear, anxiety and psychopathology
    • Korte SM (2001) Corticosteroids in relation to fear, anxiety and psychopathology. Neurosci Biobehav Rev 25: 117-142.
    • (2001) Neurosci Biobehav Rev , vol.25 , pp. 117-142
    • Korte, S.M.1
  • 36
    • 0028335927 scopus 로고
    • Progesterone and the neural mechanisms of hamster sexual behavior
    • DeBold JF, Frye CA (1994) Progesterone and the neural mechanisms of hamster sexual behavior. Psychoneuroendocrinology 19: 563-579.
    • (1994) Psychoneuroendocrinology , vol.19 , pp. 563-579
    • DeBold, J.F.1    Frye, C.A.2
  • 37
    • 0028589073 scopus 로고
    • Genomic and non-genomic actions of progesterone in the control of female hamster sexual behavior
    • DeBold JF, Frye CA (1994) Genomic and non-genomic actions of progesterone in the control of female hamster sexual behavior. Horm Behav 28: 445-453.
    • (1994) Horm Behav , vol.28 , pp. 445-453
    • DeBold, J.F.1    Frye, C.A.2
  • 38
    • 33845417567 scopus 로고    scopus 로고
    • Functional significance of the rapid regulation of brain estrogen action: Where do the estrogens come from?
    • Cornil CA, Ball GF, Balthazart J (2006) Functional significance of the rapid regulation of brain estrogen action: where do the estrogens come from? Brain Res 1126: 2-26.
    • (2006) Brain Res , vol.1126 , pp. 2-26
    • Cornil, C.A.1    Ball, G.F.2    Balthazart, J.3
  • 39
    • 0026032108 scopus 로고
    • Non-genomic and genomic effects of steroids on neural activity
    • McEwen BS (1991) Non-genomic and genomic effects of steroids on neural activity. Trends Pharmacol Sci 12: 141-147.
    • (1991) Trends Pharmacol Sci , vol.12 , pp. 141-147
    • McEwen, B.S.1
  • 40
    • 0014826583 scopus 로고
    • Hormonal control of sexual receptivity during the estrous cycle of the rat
    • Powers JB (1970) Hormonal control of sexual receptivity during the estrous cycle of the rat. Physiology and Behavior 5: 831-835.
    • (1970) Physiology and Behavior , vol.5 , pp. 831-835
    • Powers, J.B.1
  • 42
    • 0025298236 scopus 로고
    • Facilitation of sexual receptivity in hamsters by simultaneous progesterone implants into the VMH and ventral mesencephalon
    • Pleim ET, Lisciotto CA, DeBold JF (1990) Facilitation of sexual receptivity in hamsters by simultaneous progesterone implants into the VMH and ventral mesencephalon. Horm Behav 24: 139-151.
    • (1990) Horm Behav , vol.24 , pp. 139-151
    • Pleim, E.T.1    Lisciotto, C.A.2    DeBold, J.F.3
  • 43
    • 0028180389 scopus 로고
    • 5 alpha-reduced progesterone metabolites are essential in hamster VTA for sexual receptivity
    • Frye CA, Leadbetter EA (1994) 5 alpha-reduced progesterone metabolites are essential in hamster VTA for sexual receptivity. Life Sci 54: 653-659.
    • (1994) Life Sci , vol.54 , pp. 653-659
    • Frye, C.A.1    Leadbetter, E.A.2
  • 44
    • 34250847013 scopus 로고    scopus 로고
    • Neurosteroids, neuroactive steroids, and symptoms of affective disorders
    • Dubrovsky B (2006) Neurosteroids, neuroactive steroids, and symptoms of affective disorders. Pharmacol Biochem Behav 84: 644-655.
    • (2006) Pharmacol Biochem Behav , vol.84 , pp. 644-655
    • Dubrovsky, B.1
  • 45
    • 0032922384 scopus 로고    scopus 로고
    • Neuropsychopharmacological properties of neuroactive steroids
    • Rupprecht R, Holsboer F (1999) Neuropsychopharmacological properties of neuroactive steroids. Steroids 64: 83-91.
    • (1999) Steroids , vol.64 , pp. 83-91
    • Rupprecht, R.1    Holsboer, F.2
  • 46
    • 0025617803 scopus 로고
    • Steroid effects on neuronal activity: When is the genome involved? Ciba Found Symp 153: 3-12; discussion
    • McEwen BS, Coirini H, Schumacher M (1990) Steroid effects on neuronal activity: when is the genome involved? Ciba Found Symp 153: 3-12; discussion 12-21: 3-12.
    • (1990) , vol.12-21 , pp. 3-12
    • McEwen, B.S.1    Coirini, H.2    Schumacher, M.3
  • 47
    • 0036080452 scopus 로고    scopus 로고
    • Progestin receptor immunoreactivity within steroid-responsive vasopressin-immunoreactive cells in the male and female rat brain
    • Auger CJ, De Vries GJ (2002) Progestin receptor immunoreactivity within steroid-responsive vasopressin-immunoreactive cells in the male and female rat brain. J Neuroendocrinol 14: 561-567.
    • (2002) J Neuroendocrinol , vol.14 , pp. 561-567
    • Auger, C.J.1    De Vries, G.J.2
  • 48
    • 1642399711 scopus 로고    scopus 로고
    • Profound impairment in social recognition and reduction in anxiety-like behavior in vasopressin V1a receptor knockout mice
    • Bielsky IF, Hu SB, Szegda KL, Westphal H, Young LJ (2004) Profound impairment in social recognition and reduction in anxiety-like behavior in vasopressin V1a receptor knockout mice. Neuropsychopharmacology 29: 483-493.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 483-493
    • Bielsky, I.F.1    Hu, S.B.2    Szegda, K.L.3    Westphal, H.4    Young, L.J.5
  • 49
    • 11844286907 scopus 로고    scopus 로고
    • The central vasopressinergic system: Examining the opportunities for psychiatric drug development
    • Ring RH (2005) The central vasopressinergic system: examining the opportunities for psychiatric drug development. Curr Pharm Des 11: 205-225.
    • (2005) Curr Pharm Des , vol.11 , pp. 205-225
    • Ring, R.H.1
  • 50
    • 0028981589 scopus 로고
    • V1 vasopressin receptor antisense oligodeoxynuclotide into septum reduces vasopressin binding, social discrimination abilities, and anxiety-related behavior in rats
    • Landgraf R, Gerstberger R, Montkowski A, Probst JC, Wotjak CT, et al. (1995) V1 vasopressin receptor antisense oligodeoxynuclotide into septum reduces vasopressin binding, social discrimination abilities, and anxiety-related behavior in rats. J Neurosci 15: 4250-4258X.
    • (1995) J Neurosci , vol.15
    • Landgraf, R.1    Gerstberger, R.2    Montkowski, A.3    Probst, J.C.4    Wotjak, C.T.5
  • 52
    • 33645843940 scopus 로고    scopus 로고
    • Progesterone treatment of adult male rats suppresses arginine vasopressin expression in the bed nucleus of the stria terminalis and the centromedial amygdala
    • Auger CJ, Vanzo RJ (2006) Progesterone treatment of adult male rats suppresses arginine vasopressin expression in the bed nucleus of the stria terminalis and the centromedial amygdala. J Neuroendocrinol 18: 187-194.
    • (2006) J Neuroendocrinol , vol.18 , pp. 187-194
    • Auger, C.J.1    Vanzo, R.J.2
  • 53
    • 0020637321 scopus 로고
    • The origin of the vasopressinergic and oxytocinergic innervation of the rat brain with special reference to the lateral septum
    • De Vries GJ, Buijs RM (1983) The origin of the vasopressinergic and oxytocinergic innervation of the rat brain with special reference to the lateral septum. Brain Res 273: 307-317.
    • (1983) Brain Res , vol.273 , pp. 307-317
    • De Vries, G.J.1    Buijs, R.M.2
  • 55
    • 0015720099 scopus 로고
    • Neurons of the hypothalamus concentrate (3H)progesterone or its metabolites
    • Sar M, Stumpf WE (1973) Neurons of the hypothalamus concentrate (3H)progesterone or its metabolites. Science 182: 1266-1268.
    • (1973) Science , vol.182 , pp. 1266-1268
    • Sar, M.1    Stumpf, W.E.2
  • 57
    • 0020377819 scopus 로고
    • Sex differences in rat brain oestrogen and progestin receptors
    • Rainbow TC, Parsons B, McEwen BS (1982) Sex differences in rat brain oestrogen and progestin receptors. Nature 300: 648-649.
    • (1982) Nature , vol.300 , pp. 648-649
    • Rainbow, T.C.1    Parsons, B.2    McEwen, B.S.3
  • 58
    • 0017919134 scopus 로고
    • Progestin binding by brain and pituitary cell nuclei and female rat sexual behavior
    • Blaustein JD, Wade GN (1978) Progestin binding by brain and pituitary cell nuclei and female rat sexual behavior. Brain Res 140: 360-367.
    • (1978) Brain Res , vol.140 , pp. 360-367
    • Blaustein, J.D.1    Wade, G.N.2
  • 59
    • 0037470082 scopus 로고    scopus 로고
    • Role of the bed nucleus of the stria terminalis versus the amygdala in fear, stress, and anxiety
    • Walker DL, Toufexis DJ, Davis M (2003) Role of the bed nucleus of the stria terminalis versus the amygdala in fear, stress, and anxiety. Eur J Pharmacol 463: 199-216.
    • (2003) Eur J Pharmacol , vol.463 , pp. 199-216
    • Walker, D.L.1    Toufexis, D.J.2    Davis, M.3
  • 60
    • 33645457804 scopus 로고    scopus 로고
    • Progesterone's effects to reduce anxiety behavior of aged mice do not require actions via intracellular progestin receptors
    • Frye CA, Sumida K, Dudek BC, Harney JP, Lydon JP, et al. (2006) Progesterone's effects to reduce anxiety behavior of aged mice do not require actions via intracellular progestin receptors. Psychopharmacology (Berl) 186: 312-322.
    • (2006) Psychopharmacology (Berl) , vol.186 , pp. 312-322
    • Frye, C.A.1    Sumida, K.2    Dudek, B.C.3    Harney, J.P.4    Lydon, J.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.