Sex steroid induced negative mood may be explained by the paradoxical effect mediated by GABAA modulators

Psychoneuroendocrinology

Volumn 34, Issue 8, 2009, Pages 1121-1132

  Andréen, Lotta ^a   Nyberg, Sigrid ^a   Turkmen, Sharuh ^a   van Wingen, Guido ^b   Fernández, Guillen ^b   Bäckström, Torbjörn ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Allopregnanolone; Bimodal; GABAA receptor; Hormone therapy; Negative mood; PMDD

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; ALCOHOL; ALFAXALONE; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE DERIVATIVE; DIAZEPAM; ESTROGEN; FLUMAZENIL; GESTAGEN; MEDROXYPROGESTERONE ACETATE; MIDAZOLAM; ORAL CONTRACEPTIVE AGENT; PLACEBO; PROGESTERONE; SEX HORMONE;

AGGRESSION; CONFUSION; CONTRACEPTION; DEPRESSION; DISORIENTATION; DOSE RESPONSE; DRUG ANTAGONISM; DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG MEGADOSE; DRUG WITHDRAWAL; GABAERGIC SYSTEM; HORMONE ACTION; HORMONE SUBSTITUTION; HUMAN; IMPULSE CONTROL DISORDER; IRRITABILITY; LOW DRUG DOSE; MENOPAUSAL SYNDROME; MENSTRUAL CYCLE; MENTAL DISEASE; MOOD DISORDER; NONHUMAN; PREMENSTRUAL DYSPHORIC DISORDER; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; RISK FACTOR; SEDATION; SIDE EFFECT; TRANQUILIZING ACTIVITY; VIOLENCE;

AFFECT; ANIMALS; BRAIN; CONTRACEPTIVES, ORAL; FEMALE; GABA AGENTS; GONADAL STEROID HORMONES; HUMANS; MICE; MODELS, PSYCHOLOGICAL; PREGNANOLONE; PREMENSTRUAL SYNDROME;

EID: 67650585823     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2009.02.003     Document Type: Review

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