Mycoepoxydiene, a fungal polyketide inhibits MCF-7 cells through simultaneously targeting p53 and NF-κB pathways

Biochemical Pharmacology

Volumn 84, Issue 7, 2012, Pages 891-899

  Wang, Jifeng ^a   Zhao, Baobing ^a   Yi, Yuting ^a   Zhang, Wei ^a   Wu, Xuan ^a   Zhang, Lianru ^a   Shen, Yuemao ^a,b  

^a XIAMEN UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Mycoepoxydiene; NF B; P53; Polyketide; ROS

Indexed keywords

ATM PROTEIN; HEAT SHOCK PROTEIN 27; HISTONE H2AX; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYCOEPOXYDIENE; POLYKETIDE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN MCF 7; CONTROLLED STUDY; DNA DAMAGE; DRUG MECHANISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; ASCOMYCOTA; BRIDGED COMPOUNDS; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; DNA DAMAGE; GENE EXPRESSION REGULATION; HSP27 HEAT-SHOCK PROTEINS; HUMANS; NF-KAPPA B; PYRONES; REACTIVE OXYGEN SPECIES; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84865488724     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.07.004     Document Type: Article

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