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Volumn 14, Issue 6, 2010, Pages 593-601

Targeting NF-κB for colorectal cancer

Author keywords

Colorectal cancer; Inflammation; Molecular target therapy; NF B

Indexed keywords

5 ACETAMIDOSALICYLIC ACID; I KAPPA B KINASE; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 6; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; ANTINEOPLASTIC AGENT;

EID: 77952267296     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728221003769903     Document Type: Review
Times cited : (82)

References (80)
  • 2
    • 4143123301 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of the oral fluoropyrimidine s-1 on a once-daily-for-28-day schedule in patients with advanced malignancies
    • Chu QS, Hammond LA, Schwartz G, et al. Phase I and pharmacokinetic study of the oral fluoropyrimidine S-1 on a once-daily-for-28-day schedule in patients with advanced malignancies. Clin Cancer Res 2004; 10 (15) : 4913-21
    • (2004) Clin. Cancer Res. , vol.10 , Issue.15 , pp. 4913-21
    • Chu, Q.S.1    Hammond, L.A.2    Schwartz, G.3
  • 3
    • 1342290189 scopus 로고    scopus 로고
    • FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized gercor study
    • Tournigand C, Andre T, Achille E, et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 2004; 22 (2) : 229-37
    • (2004) J. Clin. Oncol. , vol.22 , Issue.2 , pp. 229-37
    • Tournigand, C.1    Andre, T.2    Achille, E.3
  • 5
    • 55249116807 scopus 로고    scopus 로고
    • Anti-egfr monoclonal antibodies in metastatic colorectal cancer: Time for an individualized approach?
    • Fakih M. Anti-EGFR monoclonal antibodies in metastatic colorectal cancer: time for an individualized approach? Expert Rev Anticancer Ther 2008; 8 (9) : 1471-80
    • (2008) Expert Rev. Anticancer Ther. , vol.8 , Issue.9 , pp. 1471-80
    • Fakih, M.1
  • 6
    • 36348951548 scopus 로고    scopus 로고
    • New approaches in angiogenic targeting for colorectal cancer
    • Prat A, Casado E, Cortes J. New approaches in angiogenic targeting for colorectal cancer. World J Gastroenterol 2007; 13 (44) : 5857-66
    • (2007) World J. Gastroenterol , vol.13 , Issue.44 , pp. 5857-66
    • Prat, A.1    Casado, E.2    Cortes, J.3
  • 7
    • 36348963081 scopus 로고    scopus 로고
    • Combining chemotherapy and targeted therapies in metastatic colorectal cancer
    • Rodriguez J, Zarate R, Bandres E, et al. Combining chemotherapy and targeted therapies in metastatic colorectal cancer. World J Gastroenterol 2007; 13 (44) : 5867-76
    • (2007) World J. Gastroenterol , vol.13 , Issue.44 , pp. 5867-76
    • Rodriguez, J.1    Zarate, R.2    Bandres, E.3
  • 8
    • 14844327760 scopus 로고    scopus 로고
    • Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting map kinase phosphatases
    • Kamata H, Honda S, Maeda S, et al. Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 2005; 120 (5) : 649-61
    • (2005) Cell. , vol.120 , Issue.5 , pp. 649-61
    • Kamata, H.1    Honda, S.2    Maeda, S.3
  • 9
    • 43649109029 scopus 로고    scopus 로고
    • Inflammation and cancer: Role of nuclear factor-kappaB activation
    • Maeda S, Omata M. Inflammation and cancer: role of nuclear factor-kappaB activation. Cancer Sci 2008; 99 (5) : 836-42
    • (2008) Cancer Sci. , vol.99 , Issue.5 , pp. 836-42
    • Maeda, S.1    Omata, M.2
  • 10
    • 4544243747 scopus 로고    scopus 로고
    • At the crossroads of inflammation and cancer
    • Clevers H. At the crossroads of inflammation and cancer. Cell 2004; 118 (6) : 671-4
    • (2004) Cell. , vol.118 , Issue.6 , pp. 671-4
    • Clevers, H.1
  • 11
    • 0036546501 scopus 로고    scopus 로고
    • Nf-kB in cancer: From innocent bystander to major culprit
    • Karin M, Cao Y, Greten FR, Li ZW. NF-kB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002; 2 (4) : 301-10
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.4 , pp. 301-10
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 12
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-kB puzzle
    • Ghosh S, Karin M. Missing pieces in the NF-kB puzzle. Cell 2002; 109 (Suppl) : S81-96
    • (2002) Cell. , vol.109 , Issue.SUPPL.
    • Ghosh, S.1    Karin, M.2
  • 13
    • 25144459131 scopus 로고    scopus 로고
    • 5-Aminosalicylate use and colorectal cancer risk in inflammatory bowel disease: A large epidemiological study
    • van Staa TP, Card T, Logan RF, Leufkens HG. 5-Aminosalicylate use and colorectal cancer risk in inflammatory bowel disease: a large epidemiological study. Gut 2005; 54 (11) : 1573-8
    • (2005) Gut , vol.54 , Issue.11 , pp. 1573-8
    • Card, T.1    Logan, R.F.2    Leufkens, H.G.3
  • 14
    • 0035080617 scopus 로고    scopus 로고
    • The risk of colorectal cancer in ulcerative colitis: A meta-analysis
    • Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut 2001; 48 (4) : 526-35
    • (2001) Gut , vol.48 , Issue.4 , pp. 526-35
    • Eaden, J.A.1    Abrams, K.R.2    Mayberry, J.F.3
  • 15
    • 0035865012 scopus 로고    scopus 로고
    • Cancer risk in patients with inflammatory bowel disease: A population-based study
    • Bernstein CN, Blanchard JF, Kliewer E, Wajda A. Cancer risk in patients with inflammatory bowel disease: a population-based study. Cancer 2001; 91 (4) : 854-62
    • (2001) Cancer , vol.91 , Issue.4 , pp. 854-62
    • Bernstein, C.N.1    Blanchard, J.F.2    Kliewer, E.3    Wajda, A.4
  • 16
  • 17
    • 0029836444 scopus 로고    scopus 로고
    • Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kB abrogates established experimental colitis in mice
    • Neurath MF, Pettersson S, Meyer zum Buschenfelde KH, Strober W. Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kB abrogates established experimental colitis in mice. Nat Med 1996; 2 (9) : 998-1004
    • (1996) Nat. Med. , vol.2 , Issue.9 , pp. 998-1004
    • Neurath, M.F.1    Pettersson, S.2    Buschenfelde, M.Z.K.H.3    Strober, W.4
  • 18
    • 0031595210 scopus 로고    scopus 로고
    • Nuclear factor kB is activated in macrophages and epithelial cells of inflamed intestinal mucosa
    • Rogler G, Brand K, Vogl D, et al. Nuclear factor kB is activated in macrophages and epithelial cells of inflamed intestinal mucosa. Gastroenterology 1998; 115 (2) : 357-69
    • (1998) Gastroenterology , vol.115 , Issue.2 , pp. 357-69
    • Rogler, G.1    Brand, K.2    Vogl, D.3
  • 19
    • 0032437063 scopus 로고    scopus 로고
    • Cytokine gene transcription by NF-kB family members in patients with inflammatory bowel disease
    • Neurath MF, Fuss I, Schurmann G, et al. Cytokine gene transcription by NF-kB family members in patients with inflammatory bowel disease. Ann NY Acad Sci 1998;859:149-59
    • (1998) Ann. NY Acad. Sci. , vol.859 , pp. 149-59
    • Neurath, M.F.1    Fuss, I.2    Schurmann, G.3
  • 20
    • 0037043658 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • Podolsky DK. Inflammatory bowel disease. N Engl J Med 2002; 347 (6) : 417-29
    • (2002) N Engl. J. Med. , vol.347 , Issue.6 , pp. 417-29
    • Podolsky, D.K.1
  • 21
    • 0141651527 scopus 로고    scopus 로고
    • Review article: The incidence and prevalence of colorectal cancer in inflammatory bowel disease
    • Munkholm P. Review article: the incidence and prevalence of colorectal cancer in inflammatory bowel disease. Aliment Pharmacol Ther 2003; 18 (Suppl 2) : 1-5
    • (2003) Aliment Pharmacol. Ther. , vol.18 , Issue.2 SUPPL. , pp. 1-5
    • Munkholm, P.1
  • 22
    • 0033579569 scopus 로고    scopus 로고
    • Aminosalicylic acid inhibits ikb kinase alpha phosphorylation of ikBalpha in mouse intestinal epithelial cells
    • Yan F, Polk DB. Aminosalicylic acid inhibits IkB kinase alpha phosphorylation of IkBalpha in mouse intestinal epithelial cells. J Biol Chem 1999; 274 (51) : 36631-6
    • (1999) J. Biol. Chem. , vol.274 , Issue.51 , pp. 36631-6
    • Yan, F.1    Polk, D.B.2
  • 23
    • 4043088499 scopus 로고    scopus 로고
    • IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • Greten FR, Eckmann L, Greten TF, et al. IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 2004; 118 (3) : 285-96
    • (2004) Cell. , vol.118 , Issue.3 , pp. 285-96
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3
  • 24
    • 5644252874 scopus 로고    scopus 로고
    • TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling
    • Becker C, Fantini MC, Schramm C, et al. TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling. Immunity 2004; 21 (4) : 491-501
    • (2004) Immunity , vol.21 , Issue.4 , pp. 491-501
    • Becker, C.1    Fantini, M.C.2    Schramm, C.3
  • 25
    • 38449110152 scopus 로고    scopus 로고
    • Cutting edge: The IkB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis
    • Shibata W, Maeda S, Hikiba Y, et al. Cutting edge: the IkB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks inflammatory injury in murine colitis. J Immunol 2007; 179 (5) : 2681-5
    • (2007) J. Immunol. , vol.179 , Issue.5 , pp. 2681-5
    • Shibata, W.1    Maeda, S.2    Hikiba, Y.3
  • 26
    • 70349652354 scopus 로고    scopus 로고
    • Effectiveness of IkB kinase inhibitors in murine colitis-associated tumorigenesis
    • Hayakawa Y, Maeda S, Nakagawa H, et al. Effectiveness of IkB kinase inhibitors in murine colitis-associated tumorigenesis. J Gastroenterol 2009; 44 (9) : 935-43
    • (2009) J. Gastroenterol , vol.44 , Issue.9 , pp. 935-43
    • Hayakawa, Y.1    Maeda, S.2    Nakagawa, H.3
  • 28
    • 0034103928 scopus 로고    scopus 로고
    • Molecular interactions in the vogelstein model of colorectal carcinoma
    • Arends JW. Molecular interactions in the Vogelstein model of colorectal carcinoma. J Pathol 2000; 190 (4) : 412-6
    • (2000) J. Pathol. , vol.190 , Issue.4 , pp. 412-6
    • Arends, J.W.1
  • 29
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100 (1) : 57-70
    • (2000) Cell. , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 30
    • 0034744949 scopus 로고    scopus 로고
    • NF-κB and cell-cycle regulation: The cyclin connection
    • Joyce D, Albanese C, Steer J, et al. NF-κB and cell-cycle regulation: the cyclin connection. Cytokine Growth Factor Rev 2001; 12 (1) : 73-90
    • (2001) Cytokine Growth Factor Rev. , vol.12 , Issue.1 , pp. 73-90
    • Joyce, D.1    Albanese, C.2    Steer, J.3
  • 31
    • 0036694663 scopus 로고    scopus 로고
    • Regulation of cytokine signaling and inflammation
    • Hanada T, Yoshimura A. Regulation of cytokine signaling and inflammation. Cytokine Growth Factor Rev 2002; 13 (4-5) : 413-21
    • (2002) Cytokine Growth Factor Rev. , vol.13 , Issue.4-5 , pp. 413-21
    • Hanada, T.1    Yoshimura, A.2
  • 32
    • 56749175339 scopus 로고    scopus 로고
    • Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism
    • Goldring MB, Otero M, Tsuchimochi K, et al. Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism. Ann Rheum Dis 2008; 67 (Suppl 3) : 75-82
    • (2008) Ann. Rheum Dis. , vol.67 , Issue.3 SUPPL. , pp. 75-82
    • Goldring, M.B.1    Otero, M.2    Tsuchimochi, K.3
  • 33
    • 33845966735 scopus 로고    scopus 로고
    • Loss of Ikkbeta promotes migration and proliferation of mouse embryo fibroblast cells
    • Chen F, Lu Y, Castranova V, et al. Loss of Ikkbeta promotes migration and proliferation of mouse embryo fibroblast cells. J Biol Chem 2006; 281 (48) : 37142-9
    • (2006) J. Biol. Chem. , vol.281 , Issue.48 , pp. 37142-9
    • Chen, F.1    Lu, Y.2    Castranova, V.3
  • 34
    • 26444605834 scopus 로고    scopus 로고
    • IKK/NF-κB signaling: Balancing life and death-a new approach to cancer therapy
    • Luo JL, Kamata H, Karin M. IKK/NF-κB signaling: balancing life and death-a new approach to cancer therapy. J Clin Invest 2005; 115 (10) : 2625-32
    • (2005) J. Clin. Invest. , vol.115 , Issue.10 , pp. 2625-32
    • Luo, J.L.1    Kamata, H.2    Karin, M.3
  • 35
    • 0035889252 scopus 로고    scopus 로고
    • Induction of gadd45beta by NF-κB downregulates pro-apoptotic JNK signalling
    • De Smaele E, Zazzeroni F, Papa S, et al. Induction of gadd45beta by NF-κB downregulates pro-apoptotic JNK signalling. Nature 2001; 414 (6861) : 308-13
    • (2001) Nature , vol.414 , Issue.6861 , pp. 308-13
    • De Smaele, E.1    Zazzeroni, F.2    Papa, S.3
  • 36
    • 13944252061 scopus 로고    scopus 로고
    • Increased expression of the e3-ubiquitin ligase receptor subunit beta TRCP1 relates to constitutive nuclear factor-kB activation and chemoresistance in pancreatic carcinoma cells
    • Muerkoster S, Arlt A, Sipos B, et al. Increased expression of the E3-ubiquitin ligase receptor subunit beta TRCP1 relates to constitutive nuclear factor-kB activation and chemoresistance in pancreatic carcinoma cells. Cancer Res 2005; 65 (4) : 1316-24
    • (2005) Cancer Res. , vol.65 , Issue.4 , pp. 1316-24
    • Muerkoster, S.1    Arlt, A.2    Sipos, B.3
  • 37
    • 0034609728 scopus 로고    scopus 로고
    • Upregulation of Bcl-x and Bfl-1 as a potential mechanism of chemoresistance, which can be overcome by NF-κB inhibition
    • Cheng Q, Lee HH, Li Y, et al. Upregulation of Bcl-x and Bfl-1 as a potential mechanism of chemoresistance, which can be overcome by NF-κB inhibition. Oncogene 2000; 19 (42) : 4936-40
    • (2000) Oncogene , vol.19 , Issue.42 , pp. 4936-40
    • Cheng, Q.1    Lee, H.H.2    Li, Y.3
  • 38
    • 34248573808 scopus 로고    scopus 로고
    • Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-κB-regulated gene products
    • Kunnumakkara AB, Guha S, Krishnan S, et al. Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-κB-regulated gene products. Cancer Res 2007; 67 (8) : 3853-61
    • (2007) Cancer Res. , vol.67 , Issue.8 , pp. 3853-61
    • Kunnumakkara, A.B.1    Guha, S.2    Krishnan, S.3
  • 39
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2002; 2 (3) : 161-74
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.3 , pp. 161-74
    • Egeblad, M.1    Werb, Z.2
  • 40
    • 65349132693 scopus 로고    scopus 로고
    • EMT, the cytoskeleton, and cancer cell invasion
    • Yilmaz M, Christofori G. EMT, the cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev 2009; 28 (1-2) : 15-33
    • (2009) Cancer Metastasis Rev. , vol.28 , Issue.1-2 , pp. 15-33
    • Yilmaz, M.1    Christofori, G.2
  • 41
    • 4344612243 scopus 로고    scopus 로고
    • NF-κB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
    • Huber MA, Azoitei N, Baumann B, et al. NF-κB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J Clin Invest 2004; 114 (4) : 569-81
    • (2004) J. Clin. Invest. , vol.114 , Issue.4 , pp. 569-81
    • Huber, M.A.1    Azoitei, N.2    Baumann, B.3
  • 42
    • 65349092794 scopus 로고    scopus 로고
    • Stabilization of snail by NF-κB is required for inflammation-induced cell migration and invasion
    • Wu Y, Deng J, Rychahou PG, et al. Stabilization of snail by NF-κB is required for inflammation-induced cell migration and invasion. Cancer Cell 2009; 15 (5) : 416-28
    • (2009) Cancer Cell. , vol.15 , Issue.5 , pp. 416-28
    • Wu, Y.1    Deng, J.2    Rychahou, P.G.3
  • 43
    • 58149269348 scopus 로고    scopus 로고
    • Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis
    • Kim S, Takahashi H, Lin WW, et al. Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis. Nature 2009; 457 (7225) : 102-6
    • (2009) Nature , vol.457 , Issue.7225 , pp. 102-6
    • Kim, S.1    Takahashi, H.2    Lin, W.W.3
  • 44
    • 73149100826 scopus 로고    scopus 로고
    • Ik B kinasebeta/nuclear factor-kB activation controls the development of liver metastasis by way of interleukin-6 expression
    • Maeda S, Hikiba Y, Sakamoto K, et al. Ik B kinasebeta/nuclear factor-kB activation controls the development of liver metastasis by way of interleukin-6 expression. Hepatology 2009; 50 (6) : 1851-60
    • (2009) Hepatology , vol.50 , Issue.6 , pp. 1851-60
    • Maeda, S.1    Hikiba, Y.2    Sakamoto, K.3
  • 45
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350 (23) : 2335-42
    • (2004) N Engl. J. Med. , vol.350 , Issue.23 , pp. 2335-42
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 46
  • 47
    • 65249141108 scopus 로고    scopus 로고
    • Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth
    • Sakamoto K, Maeda S, Hikiba Y, et al. Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth. Clin Cancer Res 2009; 15 (7) : 2248-58
    • (2009) Clin. Cancer Res. , vol.15 , Issue.7 , pp. 2248-58
    • Sakamoto, K.1    Maeda, S.2    Hikiba, Y.3
  • 48
    • 4444319419 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition of colon carcinoma involves expression of IL-8 and CXCR-1-mediated chemotaxis
    • Bates RC, DeLeo MJ III, Mercurio AM. The epithelial-mesenchymal transition of colon carcinoma involves expression of IL-8 and CXCR-1-mediated chemotaxis. Exp Cell Res 2004; 299 (2) : 315-24
    • (2004) Exp. Cell. Res. , vol.299 , Issue.2 , pp. 315-24
    • Bates, R.C.1    Deleo III, M.J.2    Mercurio, A.M.3
  • 49
    • 33645509280 scopus 로고    scopus 로고
    • A growth-related oncogene/CXC chemokine receptor 2 autocrine loop contributes to cellular proliferation in esophageal cancer
    • Wang B, Hendricks DT, Wamunyokoli F, Parker MI. A growth-related oncogene/CXC chemokine receptor 2 autocrine loop contributes to cellular proliferation in esophageal cancer. Cancer Res 2006; 66 (6) : 3071-7
    • (2006) Cancer Res. , vol.66 , Issue.6 , pp. 3071-7
    • Wang, B.1    Hendricks, D.T.2    Wamunyokoli, F.3    Parker, M.I.4
  • 50
    • 0035793566 scopus 로고    scopus 로고
    • Nuclear factor-kB activation by the CXC chemokine melanoma growth-stimulatory activity/growth-regulated protein involves the MEKK1/p38 mitogen-activated protein kinase pathway
    • Wang D, Richmond A. Nuclear factor-kB activation by the CXC chemokine melanoma growth-stimulatory activity/growth-regulated protein involves the MEKK1/p38 mitogen-activated protein kinase pathway. J Biol Chem 2001; 276 (5) : 3650-9
    • (2001) J. Biol. Chem. , vol.276 , Issue.5 , pp. 3650-9
    • Wang, D.1    Richmond, A.2
  • 51
    • 33846859568 scopus 로고    scopus 로고
    • Mcp-1 mediates TGF-beta-induced angiogenesis by stimulating vascular smooth muscle cell migration
    • Ma J, Wang Q, Fei T, et al. MCP-1 mediates TGF-beta-induced angiogenesis by stimulating vascular smooth muscle cell migration. Blood 2007; 109 (3) : 987-94
    • (2007) Blood , vol.109 , Issue.3 , pp. 987-94
    • Ma, J.1    Wang, Q.2    Fei, T.3
  • 52
    • 36148993318 scopus 로고    scopus 로고
    • Chemokines in tumor angiogenesis and metastasis
    • Singh S, Sadanandam A, Singh RK. Chemokines in tumor angiogenesis and metastasis. Cancer Metastasis Rev 2007; 26 (3-4) : 453-67
    • (2007) Cancer Metastasis Rev. , vol.26 , Issue.3-4 , pp. 453-67
    • Singh, S.1    Sadanandam, A.2    Singh, R.K.3
  • 53
    • 11144356370 scopus 로고    scopus 로고
    • CXCL1/macrophage inflammatory protein-2-induced angiogenesis in vivo is mediated by neutrophil-derived vascular endothelial growth factor-A
    • Scapini P, Morini M, Tecchio C, et al. CXCL1/macrophage inflammatory protein-2-induced angiogenesis in vivo is mediated by neutrophil-derived vascular endothelial growth factor-A. J Immunol 2004; 172 (8) : 5034-40
    • (2004) J. Immunol. , vol.172 , Issue.8 , pp. 5034-40
    • Scapini, P.1    Morini, M.2    Tecchio, C.3
  • 54
    • 33846358581 scopus 로고    scopus 로고
    • Constitutive NF-kappab activity in colorectal cancer cells: Impact on radiation-induced NF-kappab activity, radiosensitivity, and apoptosis
    • Voboril R, Weberova-Voborilova J. Constitutive NF-kappaB activity in colorectal cancer cells: impact on radiation-induced NF-kappaB activity, radiosensitivity, and apoptosis. Neoplasma 2006; 53 (6) : 518-23
    • (2006) Neoplasma , vol.53 , Issue.6 , pp. 518-23
    • Voboril, R.1    Weberova-Voborilova, J.2
  • 55
    • 0034896686 scopus 로고    scopus 로고
    • Nuclear factor-KB is upregulated in colorectal cancer
    • Lind DS, Hochwald SN, Malaty J, et al. Nuclear factor-kB is upregulated in colorectal cancer. Surgery 2001; 130 (2) : 363-9
    • (2001) Surgery , vol.130 , Issue.2 , pp. 363-9
    • Lind, D.S.1    Hochwald, S.N.2    Malaty, J.3
  • 56
    • 53049083867 scopus 로고    scopus 로고
    • Mechanisms of proteasome inhibitor action and resistance in cancer
    • McConkey DJ, Zhu K. Mechanisms of proteasome inhibitor action and resistance in cancer. Drug Resist Updat 2008; 11 (4-5) : 164-79
    • (2008) Drug Resist Updat , vol.11 , Issue.4-5 , pp. 164-79
    • McConkey, D.J.1    Zhu, K.2
  • 57
    • 0642349188 scopus 로고    scopus 로고
    • Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts
    • Williams S, Pettaway C, Song R, et al. Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts. Mol Cancer Ther 2003; 2 (9) : 835-43
    • (2003) Mol. Cancer Ther. , vol.2 , Issue.9 , pp. 835-43
    • Williams, S.1    Pettaway, C.2    Song, R.3
  • 58
    • 33645737411 scopus 로고    scopus 로고
    • Aggresome disruption: A novel strategy to enhance bortezomib-induced apoptosis in pancreatic cancer cells
    • Nawrocki ST, Carew JS, Pino MS, et al. Aggresome disruption: a novel strategy to enhance bortezomib-induced apoptosis in pancreatic cancer cells. Cancer Res 2006; 66 (7) : 3773-81
    • (2006) Cancer Res. , vol.66 , Issue.7 , pp. 3773-81
    • Nawrocki, S.T.1    Carew, J.S.2    Pino, M.S.3
  • 59
    • 22344442683 scopus 로고    scopus 로고
    • Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, velcade) and other proteasome inhibitors
    • Zhu H, Zhang L, Dong F, et al. Bik/NBK accumulation correlates with apoptosis-induction by bortezomib (PS-341, Velcade) and other proteasome inhibitors. Oncogene 2005; 24 (31) : 4993-9
    • (2005) Oncogene , vol.24 , Issue.31 , pp. 4993-9
    • Zhu, H.1    Zhang, L.2    Dong, F.3
  • 60
    • 57649210801 scopus 로고    scopus 로고
    • An eortc phase I study of bortezomib in combination with oxaliplatin, leucovorin and 5-fluorouracil in patients with advanced colorectal cancer
    • Caponigro F, Lacombe D, Twelves C, et al. An EORTC phase I study of Bortezomib in combination with oxaliplatin, leucovorin and 5-fluorouracil in patients with advanced colorectal cancer. Eur J Cancer 2009; 45 (1) : 48-55
    • (2009) Eur. J. Cancer , vol.45 , Issue.1 , pp. 48-55
    • Caponigro, F.1    Lacombe, D.2    Twelves, C.3
  • 62
    • 67650726486 scopus 로고    scopus 로고
    • Multiple myeloma
    • Raab MS, Podar K, Breitkreutz I, et al. Multiple myeloma. Lancet 2009; 374 (9686) : 324-39
    • (2009) Lancet , vol.374 , Issue.9686 , pp. 324-39
    • Raab, M.S.1    Podar, K.2    Breitkreutz, I.3
  • 63
    • 0036963968 scopus 로고    scopus 로고
    • Thalidomide suppresses the interleukin 1beta-induced nfkb signaling pathway in colon cancer cells
    • Jin SH, Kim TI, Han DS, et al. Thalidomide suppresses the interleukin 1beta-induced NFkB signaling pathway in colon cancer cells. Ann NY Acad Sci 2002;973:414-8
    • (2002) Ann. NY Acad. Sci. , vol.973 , pp. 414-8
    • Jin, S.H.1    Kim, T.I.2    Han, D.S.3
  • 64
    • 61949441174 scopus 로고    scopus 로고
    • Management of acute promyelocytic leukemia: Recommendations from an expert panel on behalf of the European leukemianet
    • Sanz MA, Grimwade D, Tallman MS, et al. Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet. Blood 2009; 113 (9) : 1875-91
    • (2009) Blood , vol.113 , Issue.9 , pp. 1875-91
    • Sanz, M.A.1    Grimwade, D.2    Tallman, M.S.3
  • 65
    • 34547115481 scopus 로고    scopus 로고
    • Arsenic trioxide (As2O3) reduces the invasive and metastatic properties of cervical cancer cells in vitro and in vivo
    • Yu J, Qian H, Li Y, et al. Arsenic trioxide (As2O3) reduces the invasive and metastatic properties of cervical cancer cells in vitro and in vivo. Gynecol Oncol 2007; 106 (2) : 400-6
    • (2007) Gynecol Oncol. , vol.106 , Issue.2 , pp. 400-6
    • Yu, J.1    Qian, H.2    Li, Y.3
  • 66
    • 34248549243 scopus 로고    scopus 로고
    • Arsenic trioxide/ascorbic acid therapy in patients with refractory metastatic colorectal carcinoma: A clinical experience
    • Subbarayan PR, Lima M, Ardalan B. Arsenic trioxide/ascorbic acid therapy in patients with refractory metastatic colorectal carcinoma: a clinical experience. Acta Oncol 2007; 46 (4) : 557-61
    • (2007) Acta Oncol. , vol.46 , Issue.4 , pp. 557-61
    • Subbarayan, P.R.1    Lima, M.2    Ardalan, B.3
  • 67
    • 0033596126 scopus 로고    scopus 로고
    • Diverse agents act at multiple levels to inhibit the Rel/NF-κB signal transduction pathway
    • Epinat JC, Gilmore TD. Diverse agents act at multiple levels to inhibit the Rel/NF-κB signal transduction pathway. Oncogene 1999; 18 (49) : 6896-909
    • (1999) Oncogene , vol.18 , Issue.49 , pp. 6896-909
    • Epinat, J.C.1    Gilmore, T.D.2
  • 68
    • 0036242607 scopus 로고    scopus 로고
    • Glucocorticoids: Do we know how they work?
    • Saklatvala J. Glucocorticoids: do we know how they work? Arthritis Res 2002; 4 (3) : 146-50
    • (2002) Arthritis Res. , vol.4 , Issue.3 , pp. 146-50
    • Saklatvala, J.1
  • 69
    • 0036236473 scopus 로고    scopus 로고
    • Negative regulation of nuclear factor-kB activation and function by glucocorticoids
    • Almawi WY, Melemedjian OK. Negative regulation of nuclear factor-kB activation and function by glucocorticoids. J Mol Endocrinol 2002; 28 (2) : 69-78
    • (2002) J. Mol. Endocrinol , vol.28 , Issue.2 , pp. 69-78
    • Almawi, W.Y.1    Melemedjian, O.K.2
  • 70
    • 67650354362 scopus 로고    scopus 로고
    • Phase I trial of adjuvant hepatic arterial infusion (HAI) with floxuridine (FUDR) and dexamethasone plus systemic oxaliplatin, 5-fluorouracil and leucovorin in patients with resected liver metastases from colorectal cancer
    • Kemeny N, Capanu M, D'Angelica M, et al. Phase I trial of adjuvant hepatic arterial infusion (HAI) with floxuridine (FUDR) and dexamethasone plus systemic oxaliplatin, 5-fluorouracil and leucovorin in patients with resected liver metastases from colorectal cancer. Ann Oncol 2009; 20 (7) : 1236-41
    • (2009) Ann. Oncol. , vol.20 , Issue.7 , pp. 1236-41
    • Kemeny, N.1    Capanu, M.2    D'Angelica, M.3
  • 71
    • 33748626306 scopus 로고    scopus 로고
    • Clinical response is associated with elevated plasma interleukin-1 receptor antagonist during selective granulocyte and monocyte apheresis in patients with ulcerative colitis
    • Sakimura K, Omori T, Iwashita E, et al. Clinical response is associated with elevated plasma interleukin-1 receptor antagonist during selective granulocyte and monocyte apheresis in patients with ulcerative colitis. Dig Dis Sci 2006; 51 (9) : 1525-31
    • (2006) Dig Dis. Sci. , vol.51 , Issue.9 , pp. 1525-31
    • Sakimura, K.1    Omori, T.2    Iwashita, E.3
  • 72
    • 59149087630 scopus 로고    scopus 로고
    • Variations in the interleukin-1 receptor antagonist gene impact on survival of patients with advanced colorectal cancer
    • Graziano F, Ruzzo A, Canestrari E, et al. Variations in the interleukin-1 receptor antagonist gene impact on survival of patients with advanced colorectal cancer. Pharmacogenomics J 2009; 9 (1) : 78-84
    • (2009) Pharmacogenomics J. , vol.9 , Issue.1 , pp. 78-84
    • Graziano, F.1    Ruzzo, A.2    Canestrari, E.3
  • 73
    • 0346505340 scopus 로고    scopus 로고
    • The IKK NF-κB system: A treasure trove for drug development
    • Karin M, Yamamoto Y, Wang QM. The IKK NF-κB system: a treasure trove for drug development. Nat Rev Drug Discov 2004; 3 (1) : 17-26
    • (2004) Nat. Rev. Drug Discov. , vol.3 , Issue.1 , pp. 17-26
    • Karin, M.1    Yamamoto, Y.2    Wang, Q.M.3
  • 74
    • 0030707537 scopus 로고    scopus 로고
    • Ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-rel oncoprotein
    • You M, Ku PT, Hrdlickova R, Bose HR Jr. ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein. Mol Cell Biol 1997; 17 (12) : 7328-41
    • (1997) Mol. Cell. Biol. , vol.17 , Issue.12 , pp. 7328-41
    • You, M.1    Ku, P.T.2    Hrdlickova, R.3    Bose Jr., H.R.4
  • 75
    • 0032490670 scopus 로고    scopus 로고
    • Nuclear factor (NF)-kB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis
    • Stehlik C, de Martin R, Kumabashiri I, et al. Nuclear factor (NF)-kB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis. J Exp Med 1998; 188 (1) : 211-6
    • (1998) J. Exp. Med. , vol.188 , Issue.1 , pp. 211-6
    • Stehlik, C.1    De Martin, R.2    Kumabashiri, I.3
  • 76
    • 0032562085 scopus 로고    scopus 로고
    • Cytokine induced expression of porcine inhibitor of apoptosis protein (iap) family member is regulated by NF-κB
    • Stehlik C, de Martin R, Binder BR, Lipp J. Cytokine induced expression of porcine inhibitor of apoptosis protein (iap) family member is regulated by NF-κB. Biochem Biophys Res Commun 1998; 243 (3) : 827-32
    • (1998) Biochem. Biophys. Res. Commun. , vol.243 , Issue.3 , pp. 827-32
    • Stehlik, C.1    De Martin, R.2    Binder, B.R.3    Lipp, J.4
  • 77
    • 0030698127 scopus 로고    scopus 로고
    • The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
    • Roy N, Deveraux QL, Takahashi R, et al. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J 1997; 16 (23) : 6914-25
    • (1997) EMBO J. , vol.16 , Issue.23 , pp. 6914-25
    • Roy, N.1    Deveraux, Q.L.2    Takahashi, R.3
  • 78
    • 36048999753 scopus 로고    scopus 로고
    • Iap antagonists induce autoubiquitination of c-IAPS, NF-κB activation, and TNFalpha-dependent apoptosis
    • Varfolomeev E, Blankenship JW, Wayson SM, et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-κB activation, and TNFalpha-dependent apoptosis. Cell 2007; 131 (4) : 669-81
    • (2007) Cell. , vol.131 , Issue.4 , pp. 669-81
    • Varfolomeev, E.1    Blankenship, J.W.2    Wayson, S.M.3
  • 79
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1
    • Malinin NL, Boldin MP, Kovalenko AV, Wallach D. MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1. Nature 1997;385:540-4
    • (1997) Nature , vol.385 , pp. 540-4
    • Malinin, N.L.1    Boldin, M.P.2    Kovalenko, A.V.3    Wallach, D.4
  • 80
    • 5644302162 scopus 로고    scopus 로고
    • Receptor-specific signaling for both the alternative and the canonical NF-κB activation pathways by NF-B-inducing kinase
    • Ramakrishnan P, Wang W, Wallach D. Receptor-specific signaling for both the alternative and the canonical NF-κB activation pathways by NF-B-inducing kinase. Immunity 2004; 21 (4) : 477-89
    • (2004) Immunity , vol.21 , Issue.4 , pp. 477-89
    • Ramakrishnan, P.1    Wang, W.2    Wallach, D.3


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