메뉴 건너뛰기




Volumn 7, Issue 8, 2012, Pages

Variability in the precore and core promoter regions of HBV strains in morocco: Characterization and impact on liver disease progression

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B(E) ANTIGEN; VIRUS DNA;

EID: 84865058919     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042891     Document Type: Article
Times cited : (35)

References (53)
  • 1
    • 77956417628 scopus 로고    scopus 로고
    • Hepatitis B vaccines
    • World Health Organization
    • World Health Organization ((2009)) Hepatitis B vaccines. Weekly Epidemiological Record 40:: 405--420.
    • (2009) Weekly Epidemiological Record , vol.40 , pp. 405-420
  • 2
    • 1642410856 scopus 로고    scopus 로고
    • Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures
    • Lavanchy D, ((2004)) Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J Viral Hepat 11:: 97--107.
    • (2004) J Viral Hepat , vol.11 , pp. 97-107
    • Lavanchy, D.1
  • 5
    • 57049098860 scopus 로고    scopus 로고
    • Epidémiologie de l′infection par les hépatites virales B et C
    • Mrani S, Sakhsokh Y, Gille Y, Baaj A, ((2002)) Epidémiologie de l′infection par les hépatites virales B et C. Cah Med. 4:: 87--88.
    • (2002) Cah Med , vol.4 , pp. 87-88
    • Mrani, S.1    Sakhsokh, Y.2    Gille, Y.3    Baaj, A.4
  • 6
    • 0021669955 scopus 로고
    • Acute viral hepatitis and hepatitis B virus markers in chronic liver disease and primary cancer of the liver
    • Sebti MF (1984) Acute viral hepatitis and hepatitis B virus markers in chronic liver disease and primary cancer of the liver. IARC Sci Publ: 227-236.
    • (1984) IARC Sci Publ , pp. 227-236
    • Sebti, M.F.1
  • 7
    • 34447325879 scopus 로고    scopus 로고
    • The Pro variant of the p53 codon 72 polymorphism is associated with hepatocellular carcinoma in Moroccan population
    • Ezzikouri S, El Feydi AE, Chafik A, Benazzouz M, El Kihal L, et al. ((2007)) The Pro variant of the p53 codon 72 polymorphism is associated with hepatocellular carcinoma in Moroccan population. Hepatol Res 37:: 748--754.
    • (2007) Hepatol Res , vol.37 , pp. 748-754
    • Ezzikouri, S.1    El Feydi, A.E.2    Chafik, A.3    Benazzouz, M.4    El Kihal, L.5
  • 8
    • 79959582910 scopus 로고    scopus 로고
    • Hepatitis B genotypes/subgenotypes and MHR variants among Moroccan chronic carriers
    • Kitab B, El Feydi AE, Afifi R, Derdabi O, Cherradi Y, et al. ((2011)) Hepatitis B genotypes/subgenotypes and MHR variants among Moroccan chronic carriers. J Infect 63:: 66--75.
    • (2011) J Infect , vol.63 , pp. 66-75
    • Kitab, B.1    El Feydi, A.E.2    Afifi, R.3    Derdabi, O.4    Cherradi, Y.5
  • 9
    • 84861925793 scopus 로고    scopus 로고
    • HBV genotypes prevalence, precore and basal core mutants in Morocco
    • Baha W, Ennaji MM, Lazar F, Melloul M, El Fahime E, et al. ((2012)) HBV genotypes prevalence, precore and basal core mutants in Morocco. Infect Genet Evol 12:: 1157--1162.
    • (2012) Infect Genet Evol , vol.12 , pp. 1157-1162
    • Baha, W.1    Ennaji, M.M.2    Lazar, F.3    Melloul, M.4    El Fahime, E.5
  • 10
    • 1542316127 scopus 로고    scopus 로고
    • Hepatitis B virus infection-natural history and clinical consequences
    • Ganem D, Prince AM, ((2004)) Hepatitis B virus infection-natural history and clinical consequences. N Engl J Med 350:: 1118--1129.
    • (2004) N Engl J Med , vol.350 , pp. 1118-1129
    • Ganem, D.1    Prince, A.M.2
  • 11
    • 79958796264 scopus 로고    scopus 로고
    • Natural history of chronic hepatitis B in Euro- Mediterranean and African countries
    • Hadziyannis SJ, ((2011)) Natural history of chronic hepatitis B in Euro- Mediterranean and African countries. J Hepatol 55:: 183--191.
    • (2011) J Hepatol , vol.55 , pp. 183-191
    • Hadziyannis, S.J.1
  • 12
    • 0036902495 scopus 로고    scopus 로고
    • World-wide epidemiology of HBeAg-negative chronic hepatitis B and associated precore and core promoter variants
    • Funk ML, Rosenberg DM, Lok AS (2002) World-wide epidemiology of HBeAg-negative chronic hepatitis B and associated precore and core promoter variants. J Viral Hepat 9: 52-61.
    • (2002) J Viral Hepat , vol.9 , pp. 52-61
    • Funk, M.L.1    Rosenberg, D.M.2    Lok, A.S.3
  • 13
    • 0031771112 scopus 로고    scopus 로고
    • Structure and function of the encapsidation signal of hepadnaviridae
    • Kramvis A, Kew MC, ((1998)) Structure and function of the encapsidation signal of hepadnaviridae. J Viral Hepat 5:: 357--367.
    • (1998) J Viral Hepat , vol.5 , pp. 357-367
    • Kramvis, A.1    Kew, M.C.2
  • 14
    • 0024427902 scopus 로고
    • Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection
    • Carman WF, Jacyna MR, Hadziyannis S, Karayiannis P, McGarvey MJ, et al. ((1989)) Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection. Lancet 2:: 588--591.
    • (1989) Lancet , vol.2 , pp. 588-591
    • Carman, W.F.1    Jacyna, M.R.2    Hadziyannis, S.3    Karayiannis, P.4    McGarvey, M.J.5
  • 15
    • 0032731871 scopus 로고    scopus 로고
    • The core promoter of hepatitis B virus
    • Kramvis A, Kew MC, ((1999)) The core promoter of hepatitis B virus. J Viral Hepat 6:: 415--427.
    • (1999) J Viral Hepat , vol.6 , pp. 415-427
    • Kramvis, A.1    Kew, M.C.2
  • 16
    • 14744299915 scopus 로고    scopus 로고
    • Relationship of genotypes of hepatitis B virus to mutations, disease progression and response to antiviral therapy
    • Kramvis A, Kew MC, ((2005)) Relationship of genotypes of hepatitis B virus to mutations, disease progression and response to antiviral therapy. J Viral Hepat 12:: 456--464.
    • (2005) J Viral Hepat , vol.12 , pp. 456-464
    • Kramvis, A.1    Kew, M.C.2
  • 17
    • 36348986710 scopus 로고    scopus 로고
    • Basal core promoter T1762/A1764 and precore A1896 gene mutations in hepatitis B surface antigen-positive hepatocellular carcinoma: a comparison with chronic carriers
    • Tong MJ, Blatt LM, Kao JH, Cheng JT, Corey WG, ((2007)) Basal core promoter T1762/A1764 and precore A1896 gene mutations in hepatitis B surface antigen-positive hepatocellular carcinoma: a comparison with chronic carriers. Liver Int 27:: 1356--1363.
    • (2007) Liver Int , vol.27 , pp. 1356-1363
    • Tong, M.J.1    Blatt, L.M.2    Kao, J.H.3    Cheng, J.T.4    Corey, W.G.5
  • 18
    • 33747076653 scopus 로고    scopus 로고
    • Influence of genotypes and precore mutations on fulminant or chronic outcome of acute hepatitis B virus infection
    • Ozasa A, Tanaka Y, Orito E, Sugiyama M, Kang JH, et al. ((2006)) Influence of genotypes and precore mutations on fulminant or chronic outcome of acute hepatitis B virus infection. Hepatology 44:: 326--334.
    • (2006) Hepatology , vol.44 , pp. 326-334
    • Ozasa, A.1    Tanaka, Y.2    Orito, E.3    Sugiyama, M.4    Kang, J.H.5
  • 19
    • 79953172877 scopus 로고    scopus 로고
    • Results of a novel real-time PCR, sequence analysis, Inno-LiPA line probe assays in the detection of hepatitis B virus G1896A precore mutation in French blood donors
    • Ducancelle A, Servant-Delmas A, Beuvelet T, Balan V, Pivert A, et al. ((2011)) Results of a novel real-time PCR, sequence analysis, Inno-LiPA line probe assays in the detection of hepatitis B virus G1896A precore mutation in French blood donors. Pathol Biol (Paris) 59:: 21--27.
    • (2011) Pathol Biol (Paris) , vol.59 , pp. 21-27
    • Ducancelle, A.1    Servant-Delmas, A.2    Beuvelet, T.3    Balan, V.4    Pivert, A.5
  • 20
    • 0141427987 scopus 로고    scopus 로고
    • Hepatitis B virus: prevalence of precore/core promoter mutants in different clinical categories of Indian patients
    • Gandhe SS, Chadha MS, Walimbe AM, Arankalle VA, ((2003)) Hepatitis B virus: prevalence of precore/core promoter mutants in different clinical categories of Indian patients. J Viral Hepat 10:: 367--382.
    • (2003) J Viral Hepat , vol.10 , pp. 367-382
    • Gandhe, S.S.1    Chadha, M.S.2    Walimbe, A.M.3    Arankalle, V.A.4
  • 21
    • 68249152595 scopus 로고    scopus 로고
    • Associations between hepatitis B virus mutations and the risk of hepatocellular carcinoma: a meta-analysis
    • Liu S, Zhang H, Gu C, Yin J, He Y, et al. ((2009)) Associations between hepatitis B virus mutations and the risk of hepatocellular carcinoma: a meta-analysis. J Natl Cancer Inst 101:: 1066--1082.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1066-1082
    • Liu, S.1    Zhang, H.2    Gu, C.3    Yin, J.4    He, Y.5
  • 22
    • 84984549253 scopus 로고    scopus 로고
    • Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers
    • Kao JH, Chen PJ, Lai MY, Chen DS, ((2003)) Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers. Gastroenterology 124:: 327--334.
    • (2003) Gastroenterology , vol.124 , pp. 327-334
    • Kao, J.H.1    Chen, P.J.2    Lai, M.Y.3    Chen, D.S.4
  • 23
    • 0032758291 scopus 로고    scopus 로고
    • Polymorphism of precore region of hepatitis B virus DNA among patients with chronic HBV infection in Turkey
    • Bozdayi AM, Bozkaya H, Turkyilmaz A, Aslan N, Verdi H, et al. ((1999)) Polymorphism of precore region of hepatitis B virus DNA among patients with chronic HBV infection in Turkey. Infection 27:: 357--360.
    • (1999) Infection , vol.27 , pp. 357-360
    • Bozdayi, A.M.1    Bozkaya, H.2    Turkyilmaz, A.3    Aslan, N.4    Verdi, H.5
  • 24
    • 56649089786 scopus 로고    scopus 로고
    • Combined mutations in pre-s/surface and core promoter/precore regions of hepatitis B virus increase the risk of hepatocellular carcinoma: a case-control study
    • Chen CH, Changchien CS, Lee CM, Hung CH, Hu TH, et al. ((2008)) Combined mutations in pre-s/surface and core promoter/precore regions of hepatitis B virus increase the risk of hepatocellular carcinoma: a case-control study. J Infect Dis 198:: 1634--1642.
    • (2008) J Infect Dis , vol.198 , pp. 1634-1642
    • Chen, C.H.1    Changchien, C.S.2    Lee, C.M.3    Hung, C.H.4    Hu, T.H.5
  • 25
    • 0029992086 scopus 로고    scopus 로고
    • Mutations in the core promoter region of hepatitis B virus in patients with chronic hepatitis B. J Med Virol
    • Kurosaki M, Enomoto N, Asahina Y, Sakuma I, Ikeda T, et al. ((1996)) Mutations in the core promoter region of hepatitis B virus in patients with chronic hepatitis B. J Med Virol. 49:: 115--123.
    • (1996) , vol.49 , pp. 115-123
    • Kurosaki, M.1    Enomoto, N.2    Asahina, Y.3    Sakuma, I.4    Ikeda, T.5
  • 26
    • 79952115426 scopus 로고    scopus 로고
    • Temporal acquisition of sequential mutations in the enhancer II and basal core promoter of HBV in individuals at high risk for hepatocellular carcinoma
    • Bai X, Zhu Y, Jin Y, Guo X, Qian G, et al. ((2011)) Temporal acquisition of sequential mutations in the enhancer II and basal core promoter of HBV in individuals at high risk for hepatocellular carcinoma. Carcinogenesis 32:: 63--68.
    • (2011) Carcinogenesis , vol.32 , pp. 63-68
    • Bai, X.1    Zhu, Y.2    Jin, Y.3    Guo, X.4    Qian, G.5
  • 27
    • 53249091947 scopus 로고    scopus 로고
    • Sequential accumulation of the mutations in core promoter of hepatitis B virus is associated with the development of hepatocellular carcinoma in Qidong, China
    • Guo X, Jin Y, Qian G, Tu H, ((2008)) Sequential accumulation of the mutations in core promoter of hepatitis B virus is associated with the development of hepatocellular carcinoma in Qidong, China. J Hepatol 49:: 718--725.
    • (2008) J Hepatol , vol.49 , pp. 718-725
    • Guo, X.1    Jin, Y.2    Qian, G.3    Tu, H.4
  • 28
    • 0027281126 scopus 로고
    • Pre-core mutation associated with lack of hepatitis B e antigenaemia in Moroccan asymptomatic carriers of the virus
    • Benjelloun S, Tong S, Li J, Menfalout L, Trepo C, et al. ((1993)) Pre-core mutation associated with lack of hepatitis B e antigenaemia in Moroccan asymptomatic carriers of the virus. Res Virol 144:: 159--167.
    • (1993) Res Virol , vol.144 , pp. 159-167
    • Benjelloun, S.1    Tong, S.2    Li, J.3    Menfalout, L.4    Trepo, C.5
  • 29
    • 49049112904 scopus 로고    scopus 로고
    • Novel subgenotypes of hepatitis B virus genotypes C and D in Papua, Indonesia
    • Lusida MI, Nugrahaputra VE, Soetjipto, Handajani R, Nagano-Fujii M, et al. ((2008)) Novel subgenotypes of hepatitis B virus genotypes C and D in Papua, Indonesia. J Clin Microbiol 46:: 2160--2166.
    • (2008) J Clin Microbiol , vol.46 , pp. 2160-2166
    • Lusida, M.I.1    Nugrahaputra, V.E.2    Soetjipto, H.R.3    Nagano-Fujii, M.4
  • 30
    • 0025058478 scopus 로고
    • An automatic modified polymerase chain reaction procedure for hepatitis B virus DNA detection
    • Larzul D, Chevrier D, Thiers V, Guesdon JL, ((1990)) An automatic modified polymerase chain reaction procedure for hepatitis B virus DNA detection. J Virol Methods 27:: 49--60.
    • (1990) J Virol Methods , vol.27 , pp. 49-60
    • Larzul, D.1    Chevrier, D.2    Thiers, V.3    Guesdon, J.L.4
  • 32
    • 0002051540 scopus 로고    scopus 로고
    • BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT
    • Hall TA, ((1999)) BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucl Acids Symp 41:: 95--98.
    • (1999) Nucl Acids Symp , vol.41 , pp. 95-98
    • Hall, T.A.1
  • 33
    • 0036892321 scopus 로고    scopus 로고
    • Influence of hepatitis B virus genotype on the long-term outcome of chronic hepatitis B in western patients
    • Sanchez-Tapias JM, Costa J, Mas A, Bruguera M, Rodes J, ((2002)) Influence of hepatitis B virus genotype on the long-term outcome of chronic hepatitis B in western patients. Gastroenterology 123:: 1848--1856.
    • (2002) Gastroenterology , vol.123 , pp. 1848-1856
    • Sanchez-Tapias, J.M.1    Costa, J.2    Mas, A.3    Bruguera, M.4    Rodes, J.5
  • 34
    • 10744220477 scopus 로고    scopus 로고
    • Mutations in the basic core promoter region of hepatitis B virus. Relationship with precore variants and HBV genotypes in a Spanish population of HBV carriers
    • Jardi R, Rodriguez F, Buti M, Costa X, Valdes A, et al. ((2004)) Mutations in the basic core promoter region of hepatitis B virus. Relationship with precore variants and HBV genotypes in a Spanish population of HBV carriers. J Hepatol 40:: 507--514.
    • (2004) J Hepatol , vol.40 , pp. 507-514
    • Jardi, R.1    Rodriguez, F.2    Buti, M.3    Costa, X.4    Valdes, A.5
  • 35
    • 59649095213 scopus 로고    scopus 로고
    • Characteristics of hepatitis B viral strains in chronic carrier patients from North-East Algeria
    • Khelifa F, Thibault V, ((2009)) Characteristics of hepatitis B viral strains in chronic carrier patients from North-East Algeria. Pathol Biol (Paris) 57:: 107--113.
    • (2009) Pathol Biol (Paris) , vol.57 , pp. 107-113
    • Khelifa, F.1    Thibault, V.2
  • 36
    • 33644661975 scopus 로고    scopus 로고
    • Hepatitis B genotypes, precore and core promoter mutants circulating in Tunisia
    • Bahri O, Cheikh I, Hajji N, Djebbi A, Maamouri N, et al. ((2006)) Hepatitis B genotypes, precore and core promoter mutants circulating in Tunisia. J Med Virol 78:: 353--357.
    • (2006) J Med Virol , vol.78 , pp. 353-357
    • Bahri, O.1    Cheikh, I.2    Hajji, N.3    Djebbi, A.4    Maamouri, N.5
  • 37
    • 0035095207 scopus 로고    scopus 로고
    • Nucleotide divergences in the core promoter and precore region of genotype D hepatitis B virus in patients with persistently elevated or normal ALT levels
    • Bozdayi AM, Bozkaya H, Turkyilmaz AR, Sarýodlu M, Cetinkaya H, et al. ((2001)) Nucleotide divergences in the core promoter and precore region of genotype D hepatitis B virus in patients with persistently elevated or normal ALT levels. J Clin Virol 21:: 91--101.
    • (2001) J Clin Virol , vol.21 , pp. 91-101
    • Bozdayi, A.M.1    Bozkaya, H.2    Turkyilmaz, A.R.3    Sarýodlu, M.4    Cetinkaya, H.5
  • 38
    • 4544278706 scopus 로고    scopus 로고
    • A case-control study for differences among hepatitis B virus infections of genotypes A (subtypes Aa and Ae) and D
    • Tanaka Y, Hasegawa I, Kato T, Orito E, Hirashima N, et al. ((2004)) A case-control study for differences among hepatitis B virus infections of genotypes A (subtypes Aa and Ae) and D. Hepatology. 40:: 747--755.
    • (2004) Hepatology , vol.40 , pp. 747-755
    • Tanaka, Y.1    Hasegawa, I.2    Kato, T.3    Orito, E.4    Hirashima, N.5
  • 39
    • 40349103941 scopus 로고    scopus 로고
    • Virological and clinical implication of core promoter C1752/V1753 and T1764/G1766 mutations in hepatitis B virus genotype D infection in Mongolia
    • Elkady A, Tanaka Y, Kurbanov F, Oynsuren T, Mizokami M, ((2008)) Virological and clinical implication of core promoter C1752/V1753 and T1764/G1766 mutations in hepatitis B virus genotype D infection in Mongolia. J Gastroenterol Hepatol 23:: 474--481.
    • (2008) J Gastroenterol Hepatol , vol.23 , pp. 474-481
    • Elkady, A.1    Tanaka, Y.2    Kurbanov, F.3    Oynsuren, T.4    Mizokami, M.5
  • 40
    • 51049117284 scopus 로고    scopus 로고
    • Associations between hepatitis B virus genotype and mutants and the risk of hepatocellular carcinoma
    • Yang HI, Yeh SH, Chen PJ, Iloeje UH, Jen CL, et al. ((2008)) Associations between hepatitis B virus genotype and mutants and the risk of hepatocellular carcinoma. J Natl Cancer Inst 100:: 1134--1143.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1134-1143
    • Yang, H.I.1    Yeh, S.H.2    Chen, P.J.3    Iloeje, U.H.4    Jen, C.L.5
  • 41
    • 35649014367 scopus 로고    scopus 로고
    • Pre-S deletion and complex mutations of hepatitis B virus related to advanced liver disease in HBeAg-negative patients
    • Chen CH, Hung CH, Lee CM, Hu TH, Wang JH, et al. ((2007)) Pre-S deletion and complex mutations of hepatitis B virus related to advanced liver disease in HBeAg-negative patients. Gastroenterology 133:: 1466--1474.
    • (2007) Gastroenterology , vol.133 , pp. 1466-1474
    • Chen, C.H.1    Hung, C.H.2    Lee, C.M.3    Hu, T.H.4    Wang, J.H.5
  • 42
    • 0029844860 scopus 로고    scopus 로고
    • Hepatitis B virus carriers without precore mutations in hepatitis B e antigen-negative stage show more severe liver damage
    • Lindh M, Horal P, Dhillon AP, Furuta Y, Norkrans G, ((1996)) Hepatitis B virus carriers without precore mutations in hepatitis B e antigen-negative stage show more severe liver damage. Hepatology 24:: 494--501.
    • (1996) Hepatology , vol.24 , pp. 494-501
    • Lindh, M.1    Horal, P.2    Dhillon, A.P.3    Furuta, Y.4    Norkrans, G.5
  • 43
    • 45549106460 scopus 로고    scopus 로고
    • Effect of basal core promoter and pre-core mutations on hepatitis B virus replication
    • Jammeh S, Tavner F, Watson R, Thomas HC, Karayiannis P, ((2008)) Effect of basal core promoter and pre-core mutations on hepatitis B virus replication. J Gen Virol 89:: 901--909.
    • (2008) J Gen Virol , vol.89 , pp. 901-909
    • Jammeh, S.1    Tavner, F.2    Watson, R.3    Thomas, H.C.4    Karayiannis, P.5
  • 44
    • 0037230412 scopus 로고    scopus 로고
    • Precore and core promoter mutations of hepatitis B virus and hepatitis B e antigen-negative chronic hepatitis B in Korea
    • Yoo BC, Park JW, Kim HJ, Lee DH, Cha YJ, et al. ((2003)) Precore and core promoter mutations of hepatitis B virus and hepatitis B e antigen-negative chronic hepatitis B in Korea. J Hepatol 38:: 98--103.
    • (2003) J Hepatol , vol.38 , pp. 98-103
    • Yoo, B.C.1    Park, J.W.2    Kim, H.J.3    Lee, D.H.4    Cha, Y.J.5
  • 45
    • 84984550857 scopus 로고    scopus 로고
    • Hepatitis B virus basal core promoter mutation and DNA load correlate with expression of hepatitis B core antigen in patients with chronic hepatitis B
    • Liu CJ, Jeng YM, Chen CL, Cheng HR, Chen PJ, et al. ((2009)) Hepatitis B virus basal core promoter mutation and DNA load correlate with expression of hepatitis B core antigen in patients with chronic hepatitis B. J Infect Dis. 199:: 742--749.
    • (2009) J Infect Dis , vol.199 , pp. 742-749
    • Liu, C.J.1    Jeng, Y.M.2    Chen, C.L.3    Cheng, H.R.4    Chen, P.J.5
  • 46
    • 33646773989 scopus 로고    scopus 로고
    • The degrees of hepatocyte cytoplasmic expression of hepatitis B core antigen correlate with histologic activity of liver disease in the young patients with chronic hepatitis B infection
    • Kim TH, Cho EY, Oh HJ, Choi CS, Kim JW, et al. ((2006)) The degrees of hepatocyte cytoplasmic expression of hepatitis B core antigen correlate with histologic activity of liver disease in the young patients with chronic hepatitis B infection. J Korean Med Sci 21:: 279--283.
    • (2006) J Korean Med Sci , vol.21 , pp. 279-283
    • Kim, T.H.1    Cho, E.Y.2    Oh, H.J.3    Choi, C.S.4    Kim, J.W.5
  • 47
    • 33748288087 scopus 로고    scopus 로고
    • Molecular functions and biological roles of hepatitis B virus x protein
    • Tang H, Oishi N, Kaneko S, Murakami S, ((2006)) Molecular functions and biological roles of hepatitis B virus x protein. Cancer Sci 97:: 977--983.
    • (2006) Cancer Sci , vol.97 , pp. 977-983
    • Tang, H.1    Oishi, N.2    Kaneko, S.3    Murakami, S.4
  • 48
    • 0942289920 scopus 로고    scopus 로고
    • Characterization of HBV integrants in 14 hepatocellular carcinomas: association of truncated X gene and hepatocellular carcinogenesis
    • Wang Y, Lau SH, Sham JS, Wu MC, Wang T, et al. ((2004)) Characterization of HBV integrants in 14 hepatocellular carcinomas: association of truncated X gene and hepatocellular carcinogenesis. Oncogene 23:: 142--148.
    • (2004) Oncogene , vol.23 , pp. 142-148
    • Wang, Y.1    Lau, S.H.2    Sham, J.S.3    Wu, M.C.4    Wang, T.5
  • 49
    • 0036708285 scopus 로고    scopus 로고
    • Precore and core promoter mutations, hepatitis B virus DNA levels and progressive liver injury in chronic hepatitis B
    • Yotsuyanagi H, Hino K, Tomita E, Toyoda J, Yasuda K, et al. ((2002)) Precore and core promoter mutations, hepatitis B virus DNA levels and progressive liver injury in chronic hepatitis B. J Hepatol. 37:: 355--363.
    • (2002) J Hepatol , vol.37 , pp. 355-363
    • Yotsuyanagi, H.1    Hino, K.2    Tomita, E.3    Toyoda, J.4    Yasuda, K.5
  • 50
    • 0037942914 scopus 로고    scopus 로고
    • Genome replication, virion secretion, and e antigen expression of naturally occurring hepatitis B virus core promoter mutants
    • Parekh S, Zoulim F, Ahn SH, Tsai A, Li J, et al. ((2003)) Genome replication, virion secretion, and e antigen expression of naturally occurring hepatitis B virus core promoter mutants. J Virol 77:: 6601--6612.
    • (2003) J Virol , vol.77 , pp. 6601-6612
    • Parekh, S.1    Zoulim, F.2    Ahn, S.H.3    Tsai, A.4    Li, J.5
  • 51
    • 0032979682 scopus 로고    scopus 로고
    • Different hepatitis B virus genotypes are associated with different mutations in the core promoter and precore regions during hepatitis B e antigen seroconversion
    • Chan HL, Hussain M, Lok AS, ((1999)) Different hepatitis B virus genotypes are associated with different mutations in the core promoter and precore regions during hepatitis B e antigen seroconversion. Hepatology 29:: 976--984.
    • (1999) Hepatology , vol.29 , pp. 976-984
    • Chan, H.L.1    Hussain, M.2    Lok, A.S.3
  • 52
    • 33749075767 scopus 로고    scopus 로고
    • Specific mutations in enhancer II/core promoter of hepatitis B virus subgenotypes C1/C2 increase the risk of hepatocellular carcinoma
    • Tanaka Y, Mukaide M, Orito E, Yuen MF, Ito K, et al. ((2006)) Specific mutations in enhancer II/core promoter of hepatitis B virus subgenotypes C1/C2 increase the risk of hepatocellular carcinoma. J Hepatol 45:: 646--653.
    • (2006) J Hepatol , vol.45 , pp. 646-653
    • Tanaka, Y.1    Mukaide, M.2    Orito, E.3    Yuen, M.F.4    Ito, K.5
  • 53
    • 0029829534 scopus 로고    scopus 로고
    • Two core promotor mutations identified in a hepatitis B virus strain associated with fulminant hepatitis result in enhanced viral replication
    • Baumert TF, Rogers SA, Hasegawa K, Liang TJ, ((1996)) Two core promotor mutations identified in a hepatitis B virus strain associated with fulminant hepatitis result in enhanced viral replication. J Clin Invest 98:: 2268--2276.
    • (1996) J Clin Invest , vol.98 , pp. 2268-2276
    • Baumert, T.F.1    Rogers, S.A.2    Hasegawa, K.3    Liang, T.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.