Hepatitis B genotypes/subgenotypes and MHR variants among Moroccan chronic carriers

Journal of Infection

Volumn 63, Issue 1, 2011, Pages 66-75

  Kitab, Bouchra ^a   El Feydi, Abdellah Essaid ^b   Afifi, Rajaa ^b   Derdabi, Omar ^b   Cherradi, Younes ^b   Benazzouz, Mustapha ^b   Rebbani, Khadija ^a   Brahim, Ikram ^a   Salih Alj, Hanane ^c   Zoulim, Fabien ^d   Trepo, Christian ^d   Chemin, Isabelle ^d   Ezzikouri, Sayeh ^a   Benjelloun, Soumaya ^a  

^a Institut Pasteur du Maroc   (Morocco)

^b IBN SINA HOSPITAL   (Morocco)

^c FACULTÉ DES SCIENCES BEN M SIK   (Morocco)

^d INSERM   (France)

Author keywords

Ayw2; Hepatitis B virus; MHR variant; Morocco; Subgenotype D7

Indexed keywords

HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN;

ADOLESCENT; ADULT; AGED; AGING; ARTICLE; CONTROLLED STUDY; FEMALE; GENDER; GENE AMPLIFICATION; GENE SEQUENCE; GENETIC VARIABILITY; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; MAJOR CLINICAL STUDY; MAJOR HYDROPHILIC REGION; MALE; MOROCCO; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PHYLOGENY; S GENE; UNINDEXED SEQUENCE; VIRUS GENE; VIRUS LOAD; VIRUS STRAIN;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CARRIER STATE; DNA PRIMERS; FEMALE; GENE FREQUENCY; GENOTYPE; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; MALE; MIDDLE AGED; MOROCCO; MUTATION; PHYLOGENY; SEQUENCE ANALYSIS; YOUNG ADULT;

EID: 79959582910     PISSN: 01634453     EISSN: 15322742     Source Type: Journal    
DOI: 10.1016/j.jinf.2011.05.007     Document Type: Article

References (49)

1. Hepatitis B 2008 2008, World Health Organization, Accessed 10.04.10, at. http://www.who.int/mediacentre/factsheets/fs204/en.
2. Mrani S., Sakhsokh Y., Gille Y., Baaj A. Épidémiologie de l'infection par les hépatites virales B et C. Cah Med 2002, 4:87-88.
3. Djeriri K., Laurichesse H., Merle J.L., Charof R., Abouyoub A., Fontana L., et al. Hepatitis B in Moroccan health care workers. Occup Med (Lond) 2008, 58:419-424.
4. Ganem D., Prince A.M. Hepatitis B virus infection-natural history and clinical consequences. N Engl J Med 2004, 350:1118-1129.
5. Seeger C., Mason W.S. Hepatitis B virus biology. Microbiol Mol Biol Rev 2000, 64:51-68.
6. Magnius L.O., Norder H. Subtypes, genotypes and molecular epidemiology of the hepatitis B virus as reflected by sequence variability of the S-gene. Intervirology 1995, 38:24-34.
7. Norder H., Courouce A.M., Coursaget P., Echevarria J.M., Lee S.D., Mushahwar I.K., et al. Genetic diversity of hepatitis B virus strains derived worldwide: genotypes, subgenotypes, and HBsAg subtypes. Intervirology 2004, 47:289-309.
8. Tran T.T., Trinh T.N., Abe K. New complex recombinant genotype of hepatitis B virus identified in Vietnam. J Virol 2008, 82:5657-5663.
9. Tatematsu K., Tanaka Y., Kurbanov F., Sugauchi F., Mano S., Maeshiro T., et al. A genetic variant of hepatitis B virus divergent from known human and ape genotypes isolated from a Japanese patient and provisionally assigned to new genotype J. J Virol 2009, 83:10538-10547.
10. Schaefer S., Magnius L., Norder H. Under construction: classification of hepatitis B virus genotypes and subgenotypes. Intervirology 2009, 52:323-325.
11. Kramvis A., Kew M., Francois G. Hepatitis B virus genotypes. Vaccine 2005, 23:2409-2423. 10.1016/j.vaccine.2004.10.045.
12. Cao G.W. Clinical relevance and public health significance of hepatitis B virus genomic variations. World J Gastroenterol 2009, 15:5761-5769.
13. Norder H., Courouce A.M., Magnius L.O. Molecular basis of hepatitis B virus serotype variations within the four major subtypes. J Gen Virol 1992, 73:3141-3145.
14. McMahon B.J. The influence of hepatitis B virus genotype and subgenotype on the natural history of chronic hepatitis B. Hepatol Int 2009, 3:334-342.
15. Yu M.W., Yeh S.H., Chen P.J., Liaw Y.F., Lin C.L., Liu C.J., et al. Hepatitis B virus genotype and DNA level and hepatocellular carcinoma: a prospective study in men. J Natl Cancer Inst 2005, 97:265-272.
16. Kao J.H., Chen P.J., Lai M.Y., Chen D.S. Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B. Gastroenterology 2000, 118:554-559.
17. Toan N.L., Song le H., Kremsner P.G., Duy D.N., Binh V.Q., Koeberlein B., et al. Impact of the hepatitis B virus genotype and genotype mixtures on the course of liver disease in Vietnam. Hepatology 2006, 43:1375-1384.
18. Thakur V., Guptan R.C., Kazim S.N., Malhotra V., Sarin S.K. Profile, spectrum and significance of HBV genotypes in chronic liver disease patients in the Indian subcontinent. J Gastroenterol Hepatol 2002, 17:165-170.
19. Livingston S.E., Simonetti J.P., McMahon B.J., Bulkow L.R., Hurlburt K.J., Homan C.E., et al. Hepatitis B virus genotypes in Alaska native people with hepatocellular carcinoma: preponderance of genotype F. J Infect Dis 2007, 195:5-11.
20. Raimondi S., Maisonneuve P., Bruno S., Mondelli M.U. Is response to antiviral treatment influenced by hepatitis B virus genotype?. J Hepatol 2010, 52:441-449.
21. Carman W.F. The clinical significance of surface antigen variants of hepatitis B virus. J Viral Hepat 1997, 4:11-20.
22. Echevarria J.M., Avellon A. Hepatitis B virus genetic diversity. J Med Virol 2006, 78:S36-S42.
23. Avellon A., Echevarria J.M. Frequency of hepatitis B virus 'a' determinant variants in unselected Spanish chronic carriers. J Med Virol 2006, 78:24-36.
24. Sayiner A.A., Ozcan A., Sengonul A. Naturally occurring MHR variants in Turkish patients infected with hepatitis B virus. J Med Virol 2008, 80:405-410.
25. Song B.C., Kim S.H., Kim H., Ying Y.H., Kim H.J., Kim Y.J., et al. Prevalence of naturally occurring surface antigen variants of hepatitis B virus in Korean patients infected chronically. J Med Virol 2005, 76:194-202.
26. Sbai A., Bennani A., Benjouad A., Hassar M. HBV genotypes in Morocco. J Clin Virol 2007, 38:184-185. 10.1016/j.jcv.2006.09.011.
27. Ezzikouri S., Chemin I., Chafik A., Wakrim L., Nourlil J., Malki A.E., et al. Genotype determination in Moroccan hepatitis B chronic carriers. Infect Genet Evol 2008, 8:306-312. 10.1016/j.meegid.2008.01.010.
28. Chemin I., Zoulim F., Merle P., Arkhis A., Chevallier M., Kay A., et al. High incidence of hepatitis B infections among chronic hepatitis cases of unknown aetiology. J Hepatol 2001, 34:447-454.
29. Thompson J.D., Gibson T.J., Plewniak F., Jeanmougin F., Higgins D.G. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 1997, 25:4876-4882.
30. Tamura K., Dudley J., Nei M., Kumar S. MEGA4: molecular Evolutionary genetics analysis (MEGA) software version 4.0. Mol Biol Evol 2007, 24:1596-1599.
31. Hall T.A. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucl Acids Symp 1999, 41:95-98.
32. Robertson B.H., Margolis H.S. Primate hepatitis B viruses-genetic diversity, geography and evolution. Rev Med Virol 2002, 12:133-141.
33. Meldal B.H., Moula N.M., Barnes I.H., Boukef K., Allain J.P. A novel hepatitis B virus subgenotype, D7, in Tunisian blood donors. J Gen Virol 2009, 90:1622-1628.
34. Dupinay T., Restorp K., Leutscher P., Rousset D., Chemin I., Migliani R., et al. High prevalence of hepatitis B virus genotype E in Northern Madagascar indicates a West-African lineage. J Med Virol 2010, 82:1515-1526.
35. Bekondi C., Olinger C.M., Boua N., Talarmin A., Venard V., Muller C.P., et al. Characterization of hepatitis B virus strains from the Central African Republic: preliminary results. Pathol Biol (Paris) 2008, 56:310-313. 10.1016/j.patbio.2007.12.007.
36. Laoi B.N., Crowley B. Molecular characterization of hepatitis B virus (HBV) isolates, including identification of a novel recombinant, in patients with acute HBV infection attending an Irish hospital. J Med Virol 2008, 80:1554-1564.
37. Tallo T., Tefanova V., Priimagi L., Schmidt J., Katargina O., Michailov M., et al. D2: major subgenotype of hepatitis B virus in Russia and the Baltic region. J Gen Virol 2008, 89:1829-1839.
38. Gerlich W.H. Diagnostic problems caused by HBsAg mutants-a consensus report of an expert meeting. Intervirology 2004, 47:310-313.
39. De Maddalena C., Giambelli C., Tanzi E., Colzani D., Schiavini M., Milazzo L., et al. High level of genetic heterogeneity in S and P genes of genotype D hepatitis B virus. Virology 2007, 365:113-124.
40. Pineiro Y.L.F.G., Pezzano S.C., Torres C., Rodriguez C.E., Eugenia Garay M., Fainboim H.A., et al. Hepatitis B virus genetic diversity in Argentina: dissimilar genotype distribution in two different geographical regions; description of hepatitis B surface antigen variants. J Clin Virol 2008, 42:381-388.
41. Mohebbi S.R., Amini-Bavil-Olyaee S., Zali N., Noorinayer B., Derakhshan F., Chiani M., et al. Molecular epidemiology of hepatitis B virus in Iran. Clin Microbiol Infect 2008, 14:858-866.
42. Ogura Y., Kurosaki M., Asahina Y., Enomoto N., Marumo F., Sato C. Prevalence and significance of naturally occurring mutations in the surface and polymerase genes of hepatitis B virus. J Infect Dis 1999, 180:1444-1451.
43. Bahramali G., Sadeghizadeh M., Amini-Bavil-Olyaee S., Alavian S., Behzad-Behbahani A., Adeli A., et al. Clinical, virologic and phylogenetic features of hepatitis B infection in Iranian patients. World J Gastroenterol 2008, 14:5448-5453.
44. Lazarevic I., Cupic M., Delic D., Svirtlih N.S., Simonovic J., Jovanovic T. Prevalence of hepatitis B virus MHR mutations and their correlation with genotypes and antiviral therapy in chronically infected patients in Serbia. J Med Virol 2010, 82:1160-1167.
45. Stramer S.L., Wend U., Candotti D., Foster G.A., Hollinger F.B., Dodd R.Y., et al. Nucleic acid testing to detect HBV infection in blood donors. N Engl J Med 2011, 364:236-247.
46. Oon C.J., Lim G.K., Ye Z., Goh K.T., Tan K.L., Yo S.L., et al. Molecular epidemiology of hepatitis B virus vaccine variants in Singapore. Vaccine 1995, 13:699-702. 10.1016/0264-410X (94)00080-7.
47. Roque-Afonso A.M., Ferey M.P., Ly T.D., Graube A., Costa-Faria L., Samuel D., et al. Viral and clinical factors associated with surface gene variants among hepatitis B virus carriers. Antivir Ther 2007, 12:1255-1263.
48. Zaaijer H.L., van Hemert F.J., Koppelman M.H., Lukashov V.V. Independent evolution of overlapping polymerase and surface protein genes of hepatitis B virus. J Gen Virol 2007, 88:2137-2143.
49. Torresi J. The virological and clinical significance of mutations in the overlapping envelope and polymerase genes of hepatitis B virus. J Clin Virol 2002, 25:97-106.