-
1
-
-
0029992810
-
Signaling in the yeast pheromone response pathway: Specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7
-
Bardwell, L., J. G. Cook, E. C. Chang, B. R. Cairns, and J. Thorner. 1996. Signaling in the yeast pheromone response pathway: specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7. Mol. Cell. Biol. 16:3637-3650.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3637-3650
-
-
Bardwell, L.1
Cook, J.G.2
Chang, E.C.3
Cairns, B.R.4
Thorner, J.5
-
2
-
-
0029913457
-
Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase
-
Blank, J. L., P. Gerwins, E. M. Elliott, S. Sather, and G. L. Johnson. 1996. Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase. J. Biol. Chem. 271:5361-5368.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5361-5368
-
-
Blank, J.L.1
Gerwins, P.2
Elliott, E.M.3
Sather, S.4
Johnson, G.L.5
-
3
-
-
0025823448
-
ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF
-
Boulton, T. G., S. H. Nye, D. J. Robbins, N. Y. Ip, E. Radziejewska, S. D. Morgenbesser, R. A. DePinho, N. Panayotatos, M. H. Cobb, and G. D. Yancopoulos. 1991. ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell 65:663-675.
-
(1991)
Cell
, vol.65
, pp. 663-675
-
-
Boulton, T.G.1
Nye, S.H.2
Robbins, D.J.3
Ip, N.Y.4
Radziejewska, E.5
Morgenbesser, S.D.6
DePinho, R.A.7
Panayotatos, N.8
Cobb, M.H.9
Yancopoulos, G.D.10
-
4
-
-
0027983908
-
Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. Cerevisiae
-
Choi, K. Y., B. Satterberg, D. M. Lyons, and E. A. Elion. 1994. Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae. Cell 78:499-512.
-
(1994)
Cell
, vol.78
, pp. 499-512
-
-
Choi, K.Y.1
Satterberg, B.2
Lyons, D.M.3
Elion, E.A.4
-
6
-
-
0029043582
-
How MAP kinases are regulated
-
Cobb, M. H., and E. J. Goldsmith. 1995. How MAP kinases are regulated. J. Biol. Chem. 270:14843-14846.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14843-14846
-
-
Cobb, M.H.1
Goldsmith, E.J.2
-
7
-
-
0032127814
-
Differential activation of stress-activated protein kinase kinases SKK4/MKK7 and SKK1/MKK4 by the mixed-lineage kinase-2 and mitogen-activated protein kinase kinase (MKK) kinase-1
-
Cuenda, A., and D. S. Dorow. 1998. Differential activation of stress-activated protein kinase kinases SKK4/MKK7 and SKK1/MKK4 by the mixed-lineage kinase-2 and mitogen-activated protein kinase kinase (MKK) kinase-1. Biochem. J. 333:11-15.
-
(1998)
Biochem. J.
, vol.333
, pp. 11-15
-
-
Cuenda, A.1
Dorow, D.S.2
-
8
-
-
0032603404
-
Signal transduction by the c-Jun N-terminal kinase
-
Davis, R. J. 1999. Signal transduction by the c-Jun N-terminal kinase. Biochem. Soc. Symp. 64:1-12.
-
(1999)
Biochem. Soc. Symp.
, vol.64
, pp. 1-12
-
-
Davis, R.J.1
-
9
-
-
0030952084
-
Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase 1 and MKK3/ p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo
-
Deacon, K., and J. L. Blank. 1997. Characterization of the mitogen-activated protein kinase kinase 4 (MKK4)/c-Jun NH2-terminal kinase 1 and MKK3/ p38 pathways regulated by MEK kinases 2 and 3. MEK kinase 3 activates MKK3 but does not cause activation of p38 kinase in vivo. J. Biol. Chem. 272:14489-14496.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14489-14496
-
-
Deacon, K.1
Blank, J.L.2
-
11
-
-
0028329953
-
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
-
Derijard, B., M. Hibi, I. H. Wu, T. Barrett, B. Su, T. Deng, M. Karin, and R. J. Davis. 1994. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76:1025-1037.
-
(1994)
Cell
, vol.76
, pp. 1025-1037
-
-
Derijard, B.1
Hibi, M.2
Wu, I.H.3
Barrett, T.4
Su, B.5
Deng, T.6
Karin, M.7
Davis, R.J.8
-
12
-
-
0028935974
-
Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms
-
Erratum, 269:17, 1995
-
Derijard, B., J. Raingeaud, T. Barrett, I. H. Wu, J. Han, R. J. Ulevitch, and R. J. Davis. 1995. Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. Science 267:682-685. (Erratum, 269:17, 1995.)
-
(1995)
Science
, vol.267
, pp. 682-685
-
-
Derijard, B.1
Raingeaud, J.2
Barrett, T.3
Wu, I.H.4
Han, J.5
Ulevitch, R.J.6
Davis, R.J.7
-
13
-
-
0032508546
-
Routing MAP kinase cascades
-
Elion, E. A. 1998. Routing MAP kinase cascades. Science 281:1625-1626.
-
(1998)
Science
, vol.281
, pp. 1625-1626
-
-
Elion, E.A.1
-
14
-
-
0031044561
-
MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: Upstream regulators of the c-Jun amino-terminal kinases?
-
Fanger, G. R., P. Gerwins, C. Widmann, M. B. Jarpe, and G. L. Johnson. 1997. MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases? Curr. Opin. Genet. Dev. 7:67-74.
-
(1997)
Curr. Opin. Genet. Dev.
, vol.7
, pp. 67-74
-
-
Fanger, G.R.1
Gerwins, P.2
Widmann, C.3
Jarpe, M.B.4
Johnson, G.L.5
-
15
-
-
0032502772
-
Human mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuli
-
Foltz, I. N., R. E. Gerl, J. S. Wieler, M. Luckach, R. A. Salmon, and J. W. Schrader. 1998. Human mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuli. J. Biol. Chem. 273:9344-9351.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9344-9351
-
-
Foltz, I.N.1
Gerl, R.E.2
Wieler, J.S.3
Luckach, M.4
Salmon, R.A.5
Schrader, J.W.6
-
16
-
-
0032910168
-
Organization and regulation of mitogen-activated protein kinase signaling pathways
-
Garrington, T. P., and G. L. Johnson. 1999. Organization and regulation of mitogen-activated protein kinase signaling pathways. Curr. Opin. Cell Biol. 11:211-218.
-
(1999)
Curr. Opin. Cell Biol.
, vol.11
, pp. 211-218
-
-
Garrington, T.P.1
Johnson, G.L.2
-
17
-
-
0030934694
-
Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway
-
Gerwins, P., J. L. Blank, and G. L. Johnson. 1997. Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway. J. Biol. Chem. 272:8288-8295.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 8288-8295
-
-
Gerwins, P.1
Blank, J.L.2
Johnson, G.L.3
-
18
-
-
0027936755
-
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
-
Han, J., J. D. Lee, L. Bibbs, and R. J. Ulevitch. 1994. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265:808-811.
-
(1994)
Science
, vol.265
, pp. 808-811
-
-
Han, J.1
Lee, J.D.2
Bibbs, L.3
Ulevitch, R.J.4
-
19
-
-
0028985079
-
MAP kinase pathways in yeast: For mating and more
-
Herskowitz, I. 1995. MAP kinase pathways in yeast: for mating and more. Cell 80:187-197.
-
(1995)
Cell
, vol.80
, pp. 187-197
-
-
Herskowitz, I.1
-
20
-
-
0028897113
-
Transcriptional regulation by extracellular signals: Mechanisms and specificity
-
Hill, C. S., and R. Treisman. 1995. Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell 80:199-211.
-
(1995)
Cell
, vol.80
, pp. 199-211
-
-
Hill, C.S.1
Treisman, R.2
-
21
-
-
0032571362
-
Differential activation of two JNK activators, MKK7 and SEK1, by MKN28-derived nonreceptor serine/threonine kinase/ mixed lineage kinase 2
-
Hirai, S., K. Noda, T. Moriguchi, E. Nishida, A. Yamashita, T. Deyama, K. Fukuyama, and S. Ohno. 1998. Differential activation of two JNK activators, MKK7 and SEK1, by MKN28-derived nonreceptor serine/threonine kinase/ mixed lineage kinase 2. J. Biol. Chem. 273:7406-7412.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 7406-7412
-
-
Hirai, S.1
Noda, K.2
Moriguchi, T.3
Nishida, E.4
Yamashita, A.5
Deyama, T.6
Fukuyama, K.7
Ohno, S.8
-
22
-
-
0030825190
-
MKK7 is a stress-activated mitogen-activated protein kinase kinase functionally related to hemipterous
-
Holland, P. M., M. Suzanne, J. S. Campbell, S. Noselli, and J. A. Cooper. 1997. MKK7 is a stress-activated mitogen-activated protein kinase kinase functionally related to hemipterous. J. Biol. Chem. 272:24994-24998.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24994-24998
-
-
Holland, P.M.1
Suzanne, M.2
Campbell, J.S.3
Noselli, S.4
Cooper, J.A.5
-
23
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
Ichijo, H., E. Nishida, K. Irie, P. ten Dijke, M. Saitoh, T. Moriguchi, M. Takagi, K. Matsumoto, K. Mijazono, and Y. Gotoh. 1997. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275:90-94.
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
Ten Dijke, P.4
Saitoh, M.5
Moriguchi, T.6
Takagi, M.7
Matsumoto, K.8
Mijazono, K.9
Gotoh, Y.10
-
24
-
-
0032054723
-
Signal transduction by the c-Jun N-terminal kinase (JNK) - From inflammation to development
-
Ip, Y. T., and R. J. Davis. 1998. Signal transduction by the c-Jun N-terminal kinase (JNK) - from inflammation to development. Curr. Opin. Cell Biol. 10:205-219.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 205-219
-
-
Ip, Y.T.1
Davis, R.J.2
-
25
-
-
0031825424
-
Mitogen-activated protein kinase cascades as regulators of stress responses
-
Karin, M. 1998. Mitogen-activated protein kinase cascades as regulators of stress responses. Ann. N. Y. Acad. Sci. 851:139-146.
-
(1998)
Ann. N. Y. Acad. Sci.
, vol.851
, pp. 139-146
-
-
Karin, M.1
-
26
-
-
0029328342
-
Transcriptional control by protein phosphorylation: Signal transmission from the cell surface to the nucleus
-
Karin, M., and T. Hunter. 1995. Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus. Curr. Biol. 5:747-757.
-
(1995)
Curr. Biol.
, vol.5
, pp. 747-757
-
-
Karin, M.1
Hunter, T.2
-
27
-
-
0027215820
-
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
-
Lange-Carter, C. A., C. M. Pleiman, A. M. Gardner, K. J. Blunter, and G. L. Johnson. 1993. A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf. Science 260:315-319.
-
(1993)
Science
, vol.260
, pp. 315-319
-
-
Lange-Carter, C.A.1
Pleiman, C.M.2
Gardner, A.M.3
Blunter, K.J.4
Johnson, G.L.5
-
28
-
-
0032585615
-
Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro
-
Lawler, S., Y. Fleming, M. Goedert, and P. Cohen. 1998. Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro. Curr. Biol. 8:1387-1390.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1387-1390
-
-
Lawler, S.1
Fleming, Y.2
Goedert, M.3
Cohen, P.4
-
29
-
-
0030581626
-
The primary structure of p38 gamma: A new member of p38 group of MAP kinases
-
Li, Z., Y. Jiang, R. J. Ulevitch, and J. Han. 1996. The primary structure of p38 gamma: a new member of p38 group of MAP kinases. Biochem. Biophys. Res. Commun. 228:334-340.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.228
, pp. 334-340
-
-
Li, Z.1
Jiang, Y.2
Ulevitch, R.J.3
Han, J.4
-
30
-
-
0028943245
-
Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2
-
Lin, A., A. Minden, H. Martinetto, F. X. Claret, C. Lange-Carter, F. Mercurio, G. L. Johnson, and M. Karin. 1995. Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2. Science 268:286-290.
-
(1995)
Science
, vol.268
, pp. 286-290
-
-
Lin, A.1
Minden, A.2
Martinetto, H.3
Claret, F.X.4
Lange-Carter, C.5
Mercurio, F.6
Johnson, G.L.7
Karin, M.8
-
31
-
-
0030770419
-
Identification of c-Jun NH2-terminal protein kinase (JNK)-activating kinase 2 as an activator of JNK but not p38
-
Lu, X., S. Nemoto, and A. Lin. 1997. Identification of c-Jun NH2-terminal protein kinase (JNK)-activating kinase 2 as an activator of JNK but not p38. J. Biol. Chem. 272:24751-24754.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24751-24754
-
-
Lu, X.1
Nemoto, S.2
Lin, A.3
-
32
-
-
0027991228
-
Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module
-
Marcus, S., A. Polverino, M. Barr, and M. Wigler. 1994. Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module. Proc. Natl. Acad. Sci. USA 91:7762-7766.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7762-7766
-
-
Marcus, S.1
Polverino, A.2
Barr, M.3
Wigler, M.4
-
33
-
-
0028872649
-
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
-
Marshall, C. J. 1995. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80:179-185.
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
34
-
-
0033538003
-
The mixed lineage kinase DLK utilizes MKK7 and not MKK4 as substrate
-
Merrill, S. E., M. Mata, D. Nihalani, C. Zhu, X. Hu, and L. B. Holzman. 1999. The mixed lineage kinase DLK utilizes MKK7 and not MKK4 as substrate. J. Biol. Chem. 274:10195-10202.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10195-10202
-
-
Merrill, S.E.1
Mata, M.2
Nihalani, D.3
Zhu, C.4
Hu, X.5
Holzman, L.B.6
-
35
-
-
0030703604
-
Regulation and function of the JNK subgroup of MAP kinases
-
Minden, A., and M. Karin. 1997. Regulation and function of the JNK subgroup of MAP kinases. Biochim. Biophys. Acta 1333:F85-F104.
-
(1997)
Biochim. Biophys. Acta
, vol.1333
-
-
Minden, A.1
Karin, M.2
-
36
-
-
0028568217
-
Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MeKK
-
Minden, A., A. Lin, M. McMahon, C. Lange-Carter, B. Derijard, R. J. Davis, G. L. Johnson, and M. Karin. 1994. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. Science 266:1719-1723.
-
(1994)
Science
, vol.266
, pp. 1719-1723
-
-
Minden, A.1
Lin, A.2
McMahon, M.3
Lange-Carter, C.4
Derijard, B.5
Davis, R.J.6
Johnson, G.L.7
Karin, M.8
-
37
-
-
0030702895
-
A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses
-
Moriguchi, T., F. Toyoshima, N. Masuyama, H. Hanafusa, Y. Gotoh, and E. Nishida. 1997. A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses. EMBO J. 16:7045-7053.
-
(1997)
EMBO J.
, vol.16
, pp. 7045-7053
-
-
Moriguchi, T.1
Toyoshima, F.2
Masuyama, N.3
Hanafusa, H.4
Gotoh, Y.5
Nishida, E.6
-
38
-
-
0030815562
-
Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: Scaffold role of Pbs2p MAPKK
-
Posas, F., and H. Saito. 1997. Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK. Science 276:1702-1705.
-
(1997)
Science
, vol.276
, pp. 1702-1705
-
-
Posas, F.1
Saito, H.2
-
39
-
-
0028046412
-
Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade
-
Printen, J. A., and G. F. Sprague, Jr. 1994. Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade. Genetics 138:609-619.
-
(1994)
Genetics
, vol.138
, pp. 609-619
-
-
Printen, J.A.1
Sprague G.F., Jr.2
-
40
-
-
0028558986
-
Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun
-
Sanchez, I., R. T. Hughes, B. J. Mayer, K. Yee, J. R. Woodgett, J. Avruch, J. M. Kyriakis, and L. I. Zon. 1994. Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature 372: 794-798.
-
(1994)
Nature
, vol.372
, pp. 794-798
-
-
Sanchez, I.1
Hughes, R.T.2
Mayer, B.J.3
Yee, K.4
Woodgett, J.R.5
Avruch, J.6
Kyriakis, J.M.7
Zon, L.I.8
-
41
-
-
0032508538
-
MP1: A MEK binding partner that enhances enzymatic activation of the MAP kinase cascade
-
Schaeffer, H. J., A. D. Catling, S. T. Eblen, L. S. Collier, A. Krauss, and M. J. Weber. 1998. MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade. Science 281:1668-1671.
-
(1998)
Science
, vol.281
, pp. 1668-1671
-
-
Schaeffer, H.J.1
Catling, A.D.2
Eblen, S.T.3
Collier, L.S.4
Krauss, A.5
Weber, M.J.6
-
43
-
-
0029011218
-
The MAPK signaling cascade
-
Seger, R., and E. G. Krebs. 1995. The MAPK signaling cascade. FASEB J. 9:726-735.
-
(1995)
FASEB J
, vol.9
, pp. 726-735
-
-
Seger, R.1
Krebs, E.G.2
-
44
-
-
0030805915
-
P38-2, a novel mitogen-activated protein kinase with distinct properties
-
Stein, B., M. X. Yang, D. B. Young, R. Janknecht, T. Hunter, B. W. Murray, and M. S. Barbosa. 1997. p38-2, a novel mitogen-activated protein kinase with distinct properties. J. Biol. Chem. 272:19509-19517.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19509-19517
-
-
Stein, B.1
Yang, M.X.2
Young, D.B.3
Janknecht, R.4
Hunter, T.5
Murray, B.W.6
Barbosa, M.S.7
-
45
-
-
0028291525
-
JNK is involved in signal integration during costimulation of T lymphocytes
-
Su, B., E. Jacinto, M. Hibi, T. Kallunki, M. Karin, and Y. Ben-Neriah. 1994. JNK is involved in signal integration during costimulation of T lymphocytes. Cell 77:727-736.
-
(1994)
Cell
, vol.77
, pp. 727-736
-
-
Su, B.1
Jacinto, E.2
Hibi, M.3
Kallunki, T.4
Karin, M.5
Ben-Neriah, Y.6
-
46
-
-
0030175485
-
Mitogen-activated protein kinase cascades and regulation of gene expression
-
Su, B., and M. Karin. 1996. Mitogen-activated protein kinase cascades and regulation of gene expression. Curr. Opin. Immunol. 8:402-411.
-
(1996)
Curr. Opin. Immunol.
, vol.8
, pp. 402-411
-
-
Su, B.1
Karin, M.2
-
47
-
-
0029913510
-
Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family
-
Teramoto, H., O. A. Coso, H. Miyata, T. Igishi, T. Miki, and J. S. Gutkind. 1996. Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family. J. Biol. Chem. 271:27225-27228.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27225-27228
-
-
Teramoto, H.1
Coso, O.A.2
Miyata, H.3
Igishi, T.4
Miki, T.5
Gutkind, J.S.6
-
48
-
-
0030462564
-
MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6
-
Tibbies, L. A., Y. L. Ing, F. Kiefer, J. Chan, N. Iscove, J. R. Woodgett, and N. J. Lassam. 1996. MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6. EMBO J. 15:7026-7035.
-
(1996)
EMBO J.
, vol.15
, pp. 7026-7035
-
-
Tibbies, L.A.1
Ing, Y.L.2
Kiefer, F.3
Chan, J.4
Iscove, N.5
Woodgett, J.R.6
Lassam, N.J.7
-
49
-
-
0030786344
-
Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase
-
Tournier, C., A. J. Whitmarsh, J. Cavanagh, T. Barrett, and R. J. Davis. 1997. Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase. Proc. Natl. Acad. Sci. USA 94:7337-7342.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7337-7342
-
-
Tournier, C.1
Whitmarsh, A.J.2
Cavanagh, J.3
Barrett, T.4
Davis, R.J.5
-
50
-
-
0032926898
-
The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases
-
Tournier, C., A. J. Whitmarsh, J. Cavanagh, T. Barrett, and R. J. Davis. 1999. The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases. Mol. Cell. Biol. 19:1569-1581.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 1569-1581
-
-
Tournier, C.1
Whitmarsh, A.J.2
Cavanagh, J.3
Barrett, T.4
Davis, R.J.5
-
51
-
-
0029954102
-
Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase
-
Wang, X. S., K. Diener, D. Jannuzzi, D. Trollinger, T. H. Tan, H. Lichenstein, M. Zukowski, and Z. Yao. 1996. Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase. J. Biol. Chem. 271:31607-31611.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31607-31611
-
-
Wang, X.S.1
Diener, K.2
Jannuzzi, D.3
Trollinger, D.4
Tan, T.H.5
Lichenstein, H.6
Zukowski, M.7
Yao, Z.8
-
52
-
-
0032508714
-
A mammalian scaffold complex that selectively mediates MAP kinase activation
-
Whitmarsh, A. J., J. Cavanagh, C. Tournier, J. Yasuda, and R. J. Davis. 1998. A mammalian scaffold complex that selectively mediates MAP kinase activation. Science 281:1671-1674.
-
(1998)
Science
, vol.281
, pp. 1671-1674
-
-
Whitmarsh, A.J.1
Cavanagh, J.2
Tournier, C.3
Yasuda, J.4
Davis, R.J.5
-
53
-
-
0021455017
-
The structure of an antigenic determinant in a protein
-
Wilson, I. A., H. L. Niman, R. A. Houghten, A. R. Cherenson, M. L. Connolly, and R. A. Lerner. 1984. The structure of an antigenic determinant in a protein. Cell 37:767-778.
-
(1984)
Cell
, vol.37
, pp. 767-778
-
-
Wilson, I.A.1
Niman, H.L.2
Houghten, R.A.3
Cherenson, A.R.4
Connolly, M.L.5
Lerner, R.A.6
-
54
-
-
0030689618
-
Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinase
-
Wu, Z., J. Wu, E. Jacinto, and M. Karin. 1997. Molecular cloning and characterization of human JNKK2, a novel Jun NH2-terminal kinase-specific kinase. Mol. Cell. Biol. 17:7407-7416.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 7407-7416
-
-
Wu, Z.1
Wu, J.2
Jacinto, E.3
Karin, M.4
-
55
-
-
0032213146
-
JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension
-
Xia, Y., Z. Wu, B. Su, B. Murray, and M. Karin. 1998. JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension. Genes Dev. 12:3369-3381.
-
(1998)
Genes Dev.
, vol.12
, pp. 3369-3381
-
-
Xia, Y.1
Wu, Z.2
Su, B.3
Murray, B.4
Karin, M.5
-
56
-
-
0031450154
-
MEKK1 binds directly to the c-Jun N-terminal kinases/stress-activated protein kinases
-
Xu, S., and M. H. Cobb. 1997. MEKK1 binds directly to the c-Jun N-terminal kinases/stress-activated protein kinases. J. Biol. Chem. 272:32056-32060.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32056-32060
-
-
Xu, S.1
Cobb, M.H.2
-
57
-
-
0029942952
-
Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain
-
Xu, S., D. J. Robbins, L. B. Christerson, J. M. English, C. A. Vanderbilt, and M. H. Cobb. 1996. Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain. Proc. Natl. Acad. Sci. USA 93:5291-5295.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5291-5295
-
-
Xu, S.1
Robbins, D.J.2
Christerson, L.B.3
English, J.M.4
Vanderbilt, C.A.5
Cobb, M.H.6
-
58
-
-
0029551805
-
Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction
-
Yamaguchi, K., K. Shirakabe, H. Shibuya, K. Irie, I. Oishi, N. Ueno, T. Taniguchi, E. Nishida, and K. Matsumoto. 1995. Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. Science 270:2008-2011.
-
(1995)
Science
, vol.270
, pp. 2008-2011
-
-
Yamaguchi, K.1
Shirakabe, K.2
Shibuya, H.3
Irie, K.4
Oishi, I.5
Ueno, N.6
Taniguchi, T.7
Nishida, E.8
Matsumoto, K.9
-
59
-
-
0032574950
-
Molecular cloning and characterization of a human protein kinase that specifically activates c-Jun N-terminal kinase
-
Yang, J., L. New, Y. Jiang, J. Han, and B. Su. 1998. Molecular cloning and characterization of a human protein kinase that specifically activates c-Jun N-terminal kinase. Gene 212:95-102.
-
(1998)
Gene
, vol.212
, pp. 95-102
-
-
Yang, J.1
New, L.2
Jiang, Y.3
Han, J.4
Su, B.5
-
60
-
-
10544223749
-
Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes
-
Zanke, B. W., E. A. Rubie, E. Winnett, J. Chan, S. Randall, M. Parsons, K. Boudreau, M. McInnis, M. Yan, D. J. Templeton, and J. R. Woodgett. 1996. Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes. J. Biol. Chem. 271:29876-29881.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 29876-29881
-
-
Zanke, B.W.1
Rubie, E.A.2
Winnett, E.3
Chan, J.4
Randall, S.5
Parsons, M.6
Boudreau, K.7
McInnis, M.8
Yan, M.9
Templeton, D.J.10
Woodgett, J.R.11
-
61
-
-
0029055761
-
Components of a new human protein kinase signal transduction pathway
-
Zhou, G., Z. Q. Bao, and J. E. Dixon. 1995. Components of a new human protein kinase signal transduction pathway. J. Biol. Chem. 270:12665-12669.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12665-12669
-
-
Zhou, G.1
Bao, Z.Q.2
Dixon, J.E.3
|