Age-and diet-dependent requirement of DJ-1 for glucose homeostasis in mice with implications for human type 2 diabetes

Journal of Molecular Cell Biology

Volumn 4, Issue 4, 2012, Pages 221-230

  Jain, Deepak ^a   Jain, Ruchi ^a   Eberhard, Daniel ^a   Eglinger, Jan ^a,b   Bugliani, Marco ^c   Piemonti, Lorenzo ^d   Marchetti, Piero ^c   Lammert, Eckhard ^a,b  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

^c CISANELLO HOSPITAL   (Italy)

^d SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

diabetes; DJ 1; mitochondria; pancreatic islets

Indexed keywords

DJ 1 PROTEIN; GLUCOSE; INSULIN; REACTIVE OXYGEN METABOLITE;

ADULT; AGE; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; DIET; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; HUMAN; HUMAN CELL; INSULIN RELEASE; INSULINOMA; MITOCHONDRION; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; WEIGHT GAIN;

ADULT; AGED; AGED, 80 AND OVER; AGING; ANIMALS; DIABETES MELLITUS, TYPE 2; DIET; GLUCOSE; GLUCOSE INTOLERANCE; HOMEOSTASIS; HUMANS; INSULIN; INSULINOMA; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISLETS OF LANGERHANS; MICE; MICE, INBRED C57BL; MIDDLE AGED; MITOCHONDRIA; ONCOGENE PROTEINS; REACTIVE OXYGEN SPECIES; UP-REGULATION;

EID: 84864829944     PISSN: 16742788     EISSN: 17594685     Source Type: Journal    
DOI: 10.1093/jmcb/mjs025     Document Type: Article

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