메뉴 건너뛰기




Volumn 295, Issue 11, 2006, Pages 1288-1299

Sex differences of endogenous sex hormones and risk of type 2 diabetes: A systematic review and meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; SEX HORMONE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE;

EID: 33644981693     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.295.11.1288     Document Type: Review
Times cited : (1145)

References (129)
  • 1
    • 32544445368 scopus 로고    scopus 로고
    • Atlanta, Ga: US Dept of Health and Human Services, Centers for Disease Control and Prevention
    • US Centers for Disease Control and Prevention. National Diabetes Fact Sheet: United States 2005. Atlanta, Ga: US Dept of Health and Human Services, Centers for Disease Control and Prevention; 2005.
    • (2005) National Diabetes Fact Sheet: United States 2005
  • 2
    • 30744433885 scopus 로고    scopus 로고
    • Excess risk of fatal coronary heart disease associated with diabetes in men and women: Meta-analysis of 37 prospective cohort studies
    • published online ahead of print December 21, 2005
    • Huxley R, Barzi F, Woodward M. Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies [published online ahead of print December 21, 2005]. BMJ. 2006;332:73-78.
    • (2006) BMJ , vol.332 , pp. 73-78
    • Huxley, R.1    Barzi, F.2    Woodward, M.3
  • 4
    • 20544465554 scopus 로고    scopus 로고
    • Acne in adolescence - Protecting the heart but damaging the prostate later in life?
    • Ford ES, Liu S. Acne in adolescence - protecting the heart but damaging the prostate later in life? Am J Epidemiol. 2005;161:1102-1106.
    • (2005) Am J Epidemiol , vol.161 , pp. 1102-1106
    • Ford, E.S.1    Liu, S.2
  • 5
    • 4544234406 scopus 로고    scopus 로고
    • The androgenic profile of women with non-insulin-dependent diabetes mellitus
    • Tok EC, Ertunc D, Evruke C, Dilek S. The androgenic profile of women with non-insulin-dependent diabetes mellitus. J Reprod Med. 2004;49:746-752.
    • (2004) J Reprod Med , vol.49 , pp. 746-752
    • Tok, E.C.1    Ertunc, D.2    Evruke, C.3    Dilek, S.4
  • 6
    • 0026589914 scopus 로고
    • Relationship of sex hormone-binding globulin to lipid, lipoprotein, glucose, and insulin concentrations in postmenopausal women
    • Haffner SM, Dunn JF, Katz MS. Relationship of sex hormone-binding globulin to lipid, lipoprotein, glucose, and insulin concentrations in postmenopausal women. Metabolism. 1992;41:278-284.
    • (1992) Metabolism , vol.41 , pp. 278-284
    • Haffner, S.M.1    Dunn, J.F.2    Katz, M.S.3
  • 7
    • 0034889856 scopus 로고    scopus 로고
    • Insulin resistance in nonobese patients with polycystic ovary syndrome
    • Toprak S, Yonem A, Cakir B, et al. Insulin resistance in nonobese patients with polycystic ovary syndrome. Horm Res. 2001;55:65-70.
    • (2001) Horm Res , vol.55 , pp. 65-70
    • Toprak, S.1    Yonem, A.2    Cakir, B.3
  • 9
    • 0033007007 scopus 로고    scopus 로고
    • Impact of insulin and body mass index on metabolic and endocrine variables in polycystic ovary syndrome
    • Ciampelli M, Fulghesu AM, Cucinelli F, et al. Impact of insulin and body mass index on metabolic and endocrine variables in polycystic ovary syndrome. Metabolism. 1999;48:167-172.
    • (1999) Metabolism , vol.48 , pp. 167-172
    • Ciampelli, M.1    Fulghesu, A.M.2    Cucinelli, F.3
  • 10
    • 0038021584 scopus 로고    scopus 로고
    • Association of endogenous sex hormones and insulin resistance among postmenopausal women: Results from the Postmenopausal Estrogen/Progestin Intervention Trial
    • Kalish GM, Barrett-Connor E, Laughlin GA, Gulanski BI. Association of endogenous sex hormones and insulin resistance among postmenopausal women: results from the Postmenopausal Estrogen/Progestin Intervention Trial. J Clin Endocrinol Metab. 2003;88:1646-1652.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1646-1652
    • Kalish, G.M.1    Barrett-Connor, E.2    Laughlin, G.A.3    Gulanski, B.I.4
  • 12
    • 4344592692 scopus 로고    scopus 로고
    • Glucose intolerance in a large cohort of mediterranean women with polycystic ovary syndrome: Phenotype and associated factors
    • Gambineri A, Pelusi C, Manicardi E, et al. Glucose intolerance in a large cohort of mediterranean women with polycystic ovary syndrome: phenotype and associated factors. Diabetes. 2004;53:2353-2358.
    • (2004) Diabetes , vol.53 , pp. 2353-2358
    • Gambineri, A.1    Pelusi, C.2    Manicardi, E.3
  • 14
    • 0036357643 scopus 로고    scopus 로고
    • Endogenous sex hormones and the development of type 2 diabetes in older men and women: The Rancho Bernardo study
    • Oh JY, Barrett-Connor E, Wedick NM, Wingard DL. Endogenous sex hormones and the development of type 2 diabetes in older men and women: the Rancho Bernardo study. Diabetes Care. 2002;25:55-60.
    • (2002) Diabetes Care , vol.25 , pp. 55-60
    • Oh, J.Y.1    Barrett-Connor, E.2    Wedick, N.M.3    Wingard, D.L.4
  • 15
    • 0028057563 scopus 로고
    • Insulin resistance, body fat distribution, and sex hormones in men
    • Haffner SM, Karhapaa P, Mykkanen L, Laakso M. Insulin resistance, body fat distribution, and sex hormones in men. Diabetes. 1994;43:212-219.
    • (1994) Diabetes , vol.43 , pp. 212-219
    • Haffner, S.M.1    Karhapaa, P.2    Mykkanen, L.3    Laakso, M.4
  • 16
    • 0026070702 scopus 로고
    • Effect of obesity and body fat distribution on sex hormones and insulin in men
    • Pasquali R, Casimirri F, Cantobelli S, et al. Effect of obesity and body fat distribution on sex hormones and insulin in men. Metabolism. 1991;40:101-104.
    • (1991) Metabolism , vol.40 , pp. 101-104
    • Pasquali, R.1    Casimirri, F.2    Cantobelli, S.3
  • 17
    • 0013694740 scopus 로고
    • Relationship between serum sex hormones and glucose, insulin and lipid abnormalities in men with myocardial infarction
    • Phillips GB. Relationship between serum sex hormones and glucose, insulin and lipid abnormalities in men with myocardial infarction. Proc Natl Acad Sci U S A. 1977;74:1729-1733.
    • (1977) Proc Natl Acad Sci U S A , vol.74 , pp. 1729-1733
    • Phillips, G.B.1
  • 18
    • 0025083282 scopus 로고
    • Visceral fat accumulation in men is positively associated with insulin, glucose, and C-peptide levels, but negatively with testosterone levels
    • Seidell JC, Bjorntorp P, Sjostrom L, Kvist H, Sannerstedt R. Visceral fat accumulation in men is positively associated with insulin, glucose, and C-peptide levels, but negatively with testosterone levels. Metabolism. 1990;39:897-901.
    • (1990) Metabolism , vol.39 , pp. 897-901
    • Seidell, J.C.1    Bjorntorp, P.2    Sjostrom, L.3    Kvist, H.4    Sannerstedt, R.5
  • 19
    • 0026547429 scopus 로고
    • Interrelation between plasma testosterone and plasma insulin in healthy adult men: The Telecom Study
    • Simon D, Preziosi P, Barrett-Connor E, et al. Interrelation between plasma testosterone and plasma insulin in healthy adult men: the Telecom Study. Diabetologia. 1992;35:173-177.
    • (1992) Diabetologia , vol.35 , pp. 173-177
    • Simon, D.1    Preziosi, P.2    Barrett-Connor, E.3
  • 20
    • 1842538111 scopus 로고    scopus 로고
    • Association of bioavailable, free, and total testosterone with insulin resistance: Influence of sex hormone-binding globulin and body fat
    • Tsai EC, Matsumoto AM, Fujimoto WY, Boyko EJ. Association of bioavailable, free, and total testosterone with insulin resistance: influence of sex hormone-binding globulin and body fat. Diabetes Care. 2004;27:861-868.
    • (2004) Diabetes Care , vol.27 , pp. 861-868
    • Tsai, E.C.1    Matsumoto, A.M.2    Fujimoto, W.Y.3    Boyko, E.J.4
  • 21
    • 0027102382 scopus 로고
    • The effects of testosterone treatment on body composition and metabolism in middle-aged obese men
    • Marin P, Holmang S, Jonsson L, et al. The effects of testosterone treatment on body composition and metabolism in middle-aged obese men. Int J Obes Relat Metab Disord. 1992;16:991-997.
    • (1992) Int J Obes Relat Metab Disord , vol.16 , pp. 991-997
    • Marin, P.1    Holmang, S.2    Jonsson, L.3
  • 22
    • 0035654282 scopus 로고    scopus 로고
    • Androgen therapy improves insulin sensitivity and decreases leptin level in healthy adult men with low plasma total testosterone: A 3-month randomized placebo-controlled trial
    • Simon D, Charles MA, Lahlou N, et al. Androgen therapy improves insulin sensitivity and decreases leptin level in healthy adult men with low plasma total testosterone: a 3-month randomized placebo-controlled trial. Diabetes Care. 2001;24:2149-2151.
    • (2001) Diabetes Care , vol.24 , pp. 2149-2151
    • Simon, D.1    Charles, M.A.2    Lahlou, N.3
  • 23
    • 24944450769 scopus 로고    scopus 로고
    • Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men
    • Pitteloud N, Mootha VK, Dwyer AA, et al. Relationship between testosterone levels, insulin sensitivity, and mitochondrial function in men. Diabetes Care. 2005;28:1636-1642.
    • (2005) Diabetes Care , vol.28 , pp. 1636-1642
    • Pitteloud, N.1    Mootha, V.K.2    Dwyer, A.A.3
  • 24
    • 18844362098 scopus 로고    scopus 로고
    • Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men
    • Pitteloud N, Hardin M, Dwyer AA, et al. Increasing insulin resistance is associated with a decrease in Leydig cell testosterone secretion in men. J Clin Endocrinol Metab. 2005;90:2636-2641.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 2636-2641
    • Pitteloud, N.1    Hardin, M.2    Dwyer, A.A.3
  • 25
    • 0030475065 scopus 로고    scopus 로고
    • Low testosterone and insulin resistance in hypertension-prone men
    • Endre T, Mattiasson I, Berglund G, Hulthen UL. Low testosterone and insulin resistance in hypertension-prone men. J Hum Hypertens. 1996;10:755-761.
    • (1996) J Hum Hypertens , vol.10 , pp. 755-761
    • Endre, T.1    Mattiasson, I.2    Berglund, G.3    Hulthen, U.L.4
  • 27
    • 0030973135 scopus 로고    scopus 로고
    • Effects of acute hyperinsulinemia on testosterone serum concentrations in adult obese and normal-weight men
    • Pasquali R, Macor C, Vicennati V, et al. Effects of acute hyperinsulinemia on testosterone serum concentrations in adult obese and normal-weight men. Metabolism. 1997;46:526-529.
    • (1997) Metabolism , vol.46 , pp. 526-529
    • Pasquali, R.1    Macor, C.2    Vicennati, V.3
  • 28
    • 0028318112 scopus 로고
    • Hormonal changes in elderly men with non-insulin-dependent diabetes mellitus and the hormonal relationships to abdominal adiposity
    • Chang TC, Tung CC, Hsiao YL. Hormonal changes in elderly men with non-insulin-dependent diabetes mellitus and the hormonal relationships to abdominal adiposity. Gerontology. 1994;40:260-267.
    • (1994) Gerontology , vol.40 , pp. 260-267
    • Chang, T.C.1    Tung, C.C.2    Hsiao, Y.L.3
  • 29
    • 0023695139 scopus 로고
    • Endogenous sex hormones and cardiovascular disease in men: A prospective population-based study
    • Barrett-Connor E, Khaw KT. Endogenous sex hormones and cardiovascular disease in men: a prospective population-based study. Circulation. 1988;78:539-545.
    • (1988) Circulation , vol.78 , pp. 539-545
    • Barrett-Connor, E.1    Khaw, K.T.2
  • 30
    • 0029968711 scopus 로고    scopus 로고
    • Influence of some biological indexes on sex hormonebinding globulin and androgen levels in aging or obese males
    • Vermeulen A, Kaufman JM, Giagulli VA. Influence of some biological indexes on sex hormonebinding globulin and androgen levels in aging or obese males. J Clin Endocrinol Metab. 1996;81:1821-1826.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 1821-1826
    • Vermeulen, A.1    Kaufman, J.M.2    Giagulli, V.A.3
  • 32
    • 0033927079 scopus 로고    scopus 로고
    • Sex differences in the association of endogenous sex hormone levels and glucose tolerance status in older men and women
    • Goodman-Gruen D, Barrett-Connor E. Sex differences in the association of endogenous sex hormone levels and glucose tolerance status in older men and women. Diabetes Care. 2000;23:912-918.
    • (2000) Diabetes Care , vol.23 , pp. 912-918
    • Goodman-Gruen, D.1    Barrett-Connor, E.2
  • 33
    • 0028297129 scopus 로고
    • Decreased testosterone and dehydroepiandrosterone sulfate concentrations are associated with increased insulin and glucose concentrations in non-diabetic men
    • Haffner SM, Valdez RA, Mykkanen L, Stern MP, Katz MS. Decreased testosterone and dehydroepiandrosterone sulfate concentrations are associated with increased insulin and glucose concentrations in non-diabetic men. Metabolism. 1994;43:599-603.
    • (1994) Metabolism , vol.43 , pp. 599-603
    • Haffner, S.M.1    Valdez, R.A.2    Mykkanen, L.3    Stern, M.P.4    Katz, M.S.5
  • 34
    • 0242320383 scopus 로고    scopus 로고
    • Insulin resistance, hemostatic factors, and hormone interactions in pre- And perimenopausal women: SWAN
    • Sowers M, Derby C, Jannausch ML, Torrens JI, Pasternak R. Insulin resistance, hemostatic factors, and hormone interactions in pre- and perimenopausal women: SWAN. J Clin Endocrinol Metab. 2003;88:4904-4910.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4904-4910
    • Sowers, M.1    Derby, C.2    Jannausch, M.L.3    Torrens, J.I.4    Pasternak, R.5
  • 35
    • 0029874336 scopus 로고    scopus 로고
    • Low levels of sex hormone-binding globulin and testosterone predict the development of non-insulin-dependent diabetes mellitus in men
    • Haffner SM, Shaten J, Stern MP, Smith GD, Kuller L; MRFIT Research Group. Low levels of sex hormone-binding globulin and testosterone predict the development of non-insulin-dependent diabetes mellitus in men. Am J Epidemiol. 1996;143:889-897.
    • (1996) Am J Epidemiol , vol.143 , pp. 889-897
    • Haffner, S.M.1    Shaten, J.2    Stern, M.P.3    Smith, G.D.4    Kuller, L.5
  • 36
    • 14944342884 scopus 로고    scopus 로고
    • Serum androgen levels and insulin resistance in postmenopausal women: Association with hormone therapy, tibolone and raloxifene
    • Christodoulakos G, Lambrinoudaki I, Panoulis C, et al. Serum androgen levels and insulin resistance in postmenopausal women: association with hormone therapy, tibolone and raloxifene. Maturitas. 2005;50:321-330.
    • (2005) Maturitas , vol.50 , pp. 321-330
    • Christodoulakos, G.1    Lambrinoudaki, I.2    Panoulis, C.3
  • 37
    • 0027529384 scopus 로고
    • Level of sex hormone-binding globulin is positively correlated with insulin sensitivity in men with type 2 diabetes
    • Birkeland KI, Hanssen KF, Torjesen PA, Vaaler S. Level of sex hormone-binding globulin is positively correlated with insulin sensitivity in men with type 2 diabetes. J Clin Endocrinol Metab. 1993;76:275-278.
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 275-278
    • Birkeland, K.I.1    Hanssen, K.F.2    Torjesen, P.A.3    Vaaler, S.4
  • 38
    • 1842479594 scopus 로고    scopus 로고
    • Androgenicity and obesity are independently associated with insulin sensitivity in postmenopausal women
    • Lee CC, Kasa-Vubu JZ, Supiano MA. Androgenicity and obesity are independently associated with insulin sensitivity in postmenopausal women. Metabolism. 2004;53:507-512.
    • (2004) Metabolism , vol.53 , pp. 507-512
    • Lee, C.C.1    Kasa-Vubu, J.Z.2    Supiano, M.A.3
  • 40
    • 0035515324 scopus 로고    scopus 로고
    • The effects of metformin and diet on plasma testosterone and leptin levels in obese men
    • Ozata M, Oktenli C, Bingol N, Ozdemir IC. The effects of metformin and diet on plasma testosterone and leptin levels in obese men. Obes Res. 2001;9:662-667.
    • (2001) Obes Res , vol.9 , pp. 662-667
    • Ozata, M.1    Oktenli, C.2    Bingol, N.3    Ozdemir, I.C.4
  • 41
    • 0035192579 scopus 로고    scopus 로고
    • Differences in body fat distribution and antioxidant status in Korean men with cardiovascular disease with or without diabetes
    • Jang Y, Lee JH, Cho EY, Chung NS, Topham D, Balderston B. Differences in body fat distribution and antioxidant status in Korean men with cardiovascular disease with or without diabetes.AmJ Clin Nutr. 2001;73:68-74.
    • (2001) AmJ Clin Nutr , vol.73 , pp. 68-74
    • Jang, Y.1    Lee, J.H.2    Cho, E.Y.3    Chung, N.S.4    Topham, D.5    Balderston, B.6
  • 43
    • 0026053850 scopus 로고
    • Low sex-hormone-binding globulin concentration as independent risk factor for development of NIDDM: 12-yr follow-up of population study of women in Gothenburg, Sweden
    • Lindstedt G, Lundberg PA, Lapidus L, Lundgren H, Bengtsson C, Bjorntorp P. Low sex-hormone-binding globulin concentration as independent risk factor for development of NIDDM: 12-yr follow-up of population study of women in Gothenburg, Sweden. Diabetes. 1991;40:123-128.
    • (1991) Diabetes , vol.40 , pp. 123-128
    • Lindstedt, G.1    Lundberg, P.A.2    Lapidus, L.3    Lundgren, H.4    Bengtsson, C.5    Bjorntorp, P.6
  • 44
    • 0027168783 scopus 로고
    • Decreased sex hormone-binding globulin predicts noninsulin-dependent diabetes mellitus in women but not in men
    • Haffner SM, Valdez RA, Morales PA, Hazuda HP, Stern MP. Decreased sex hormone-binding globulin predicts noninsulin-dependent diabetes mellitus in women but not in men. J Clin Endocrinol Metab. 1993;77:56-60.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 56-60
    • Haffner, S.M.1    Valdez, R.A.2    Morales, P.A.3    Hazuda, H.P.4    Stern, M.P.5
  • 45
    • 0029859101 scopus 로고    scopus 로고
    • The pituitary-gonadal axis and health in elderly men: A study of men born in 1913
    • Tibblin G, Adlerberth A, Lindstedt G, Bjorntorp P. The pituitary-gonadal axis and health in elderly men: a study of men born in 1913. Diabetes. 1996;45:1605-1609.
    • (1996) Diabetes , vol.45 , pp. 1605-1609
    • Tibblin, G.1    Adlerberth, A.2    Lindstedt, G.3    Bjorntorp, P.4
  • 46
    • 0033990187 scopus 로고    scopus 로고
    • Association of sex hormone-binding globulin and insulin resistance among Japanese-American subjects
    • Okubo M, Tokui M, Egusa G, Yamakido M. Association of sex hormone-binding globulin and insulin resistance among Japanese-American subjects. Diabetes Res Clin Pract. 2000;47:71-75.
    • (2000) Diabetes Res Clin Pract , vol.47 , pp. 71-75
    • Okubo, M.1    Tokui, M.2    Egusa, G.3    Yamakido, M.4
  • 47
    • 0034106347 scopus 로고    scopus 로고
    • Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: Prospective results from the Massachusetts Male Aging Study
    • Stellato RK, Feldman HA, Hamdy O, Horton ES, McKinlay JB. Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: prospective results from the Massachusetts Male Aging Study. Diabetes Care. 2000;23:490-494.
    • (2000) Diabetes Care , vol.23 , pp. 490-494
    • Stellato, R.K.1    Feldman, H.A.2    Hamdy, O.3    Horton, E.S.4    McKinlay, J.B.5
  • 48
    • 0141862280 scopus 로고    scopus 로고
    • A 5-year follow-up study of disease incidence in men with an abnormal hormone pattern
    • Rosmond R, Wallerius S, Wanger P, Martin L, Holm G, Bjorntorp P. A 5-year follow-up study of disease incidence in men with an abnormal hormone pattern. J Intern Med. 2003;254:386-390.
    • (2003) J Intern Med , vol.254 , pp. 386-390
    • Rosmond, R.1    Wallerius, S.2    Wanger, P.3    Martin, L.4    Holm, G.5    Bjorntorp, P.6
  • 49
    • 2342644814 scopus 로고    scopus 로고
    • Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men
    • Laaksonen DE, Niskanen L, Punnonen K, et al. Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men. Diabetes Care. 2004;27:1036-1041.
    • (2004) Diabetes Care , vol.27 , pp. 1036-1041
    • Laaksonen, D.E.1    Niskanen, L.2    Punnonen, K.3
  • 51
    • 0017807616 scopus 로고
    • Differences in pituitary and testicular function between diabetic patients on insulin and oral antidiabetic agents
    • Shahwan MM, Spathis GS, Fry DE, Wood PJ, Marks V. Differences in pituitary and testicular function between diabetic patients on insulin and oral antidiabetic agents. Diabetologia. 1978;15:13-17.
    • (1978) Diabetologia , vol.15 , pp. 13-17
    • Shahwan, M.M.1    Spathis, G.S.2    Fry, D.E.3    Wood, P.J.4    Marks, V.5
  • 52
    • 0021233881 scopus 로고
    • Evidence for hyperestrogenemia as the link between diabetes mellitus and myocardial infarction
    • Phillips GB. Evidence for hyperestrogenemia as the link between diabetes mellitus and myocardial infarction. Am J Med. 1984;76:1041-1048.
    • (1984) Am J Med , vol.76 , pp. 1041-1048
    • Phillips, G.B.1
  • 53
    • 84959811438 scopus 로고
    • Oestradiol levels in diabetic men with and without a previous myocardial infarction
    • Small M, MacRury S, Beastall GH, MacCuish AC. Oestradiol levels in diabetic men with and without a previous myocardial infarction. Q J Med. 1987;64:617-623.
    • (1987) Q J Med , vol.64 , pp. 617-623
    • Small, M.1    MacRury, S.2    Beastall, G.H.3    MacCuish, A.C.4
  • 54
    • 0031854552 scopus 로고    scopus 로고
    • CALedonia DIAbetes Mellitus (CALDIA) Study Group. Hormonal status and NIDDM in the European and Melanesian populations of New Caledonia: A case-control study
    • Defay R, Papoz L, Barny S, Bonnot-Lours S, Caces E, Simon D; CALedonia DIAbetes Mellitus (CALDIA) Study Group. Hormonal status and NIDDM in the European and Melanesian populations of New Caledonia: a case-control study. Int J Obes Relat Metab Disord. 1998;22:927-934.
    • (1998) Int J Obes Relat Metab Disord , vol.22 , pp. 927-934
    • Defay, R.1    Papoz, L.2    Barny, S.3    Bonnot-Lours, S.4    Caces, E.5    Simon, D.6
  • 55
    • 0023871989 scopus 로고
    • Androgen levels in men with diabetes mellitus
    • Semple CG, Gray CE, Beastall GH. Androgen levels in men with diabetes mellitus. Diabet Med. 1988;5:122-125.
    • (1988) Diabet Med , vol.5 , pp. 122-125
    • Semple, C.G.1    Gray, C.E.2    Beastall, G.H.3
  • 57
    • 0030935655 scopus 로고    scopus 로고
    • Sex hormone-binding globulin and glucose tolerance in postmenopausal women: The Rancho Bernardo Study
    • Goodman-Gruen D, Barrett-Connor E. Sex hormone-binding globulin and glucose tolerance in postmenopausal women: the Rancho Bernardo Study. Diabetes Care. 1997;20:645-649.
    • (1997) Diabetes Care , vol.20 , pp. 645-649
    • Goodman-Gruen, D.1    Barrett-Connor, E.2
  • 58
    • 0031846884 scopus 로고    scopus 로고
    • Polycystic ovaries and associated metabolic abnormalities in Indian subcontinent Asian women
    • Rodin DA, Bano G, Bland JM, Taylor K, Nussey SS. Polycystic ovaries and associated metabolic abnormalities in Indian subcontinent Asian women. Clin Endocrinol (Oxf ). 1998;49:91-99.
    • (1998) Clin Endocrinol (Oxf ) , vol.49 , pp. 91-99
    • Rodin, D.A.1    Bano, G.2    Bland, J.M.3    Taylor, K.4    Nussey, S.S.5
  • 59
    • 0031791430 scopus 로고    scopus 로고
    • Do postmenopausal women with NIDDM have a reduced capacity to deposit and conserve lower-body fat?
    • Stoney RM, Walker KZ, Best JD, Ireland PD, Giles GG, O'Dea K. Do postmenopausal women with NIDDM have a reduced capacity to deposit and conserve lower-body fat? Diabetes Care. 1998;21:828-830.
    • (1998) Diabetes Care , vol.21 , pp. 828-830
    • Stoney, R.M.1    Walker, K.Z.2    Best, J.D.3    Ireland, P.D.4    Giles, G.G.5    O'Dea, K.6
  • 60
    • 0344286476 scopus 로고    scopus 로고
    • Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome
    • Ehrmann DA, Barnes RB, Rosenfield RL, Cavaghan MK, Imperial J. Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome. Diabetes Care. 1999;22:141-146.
    • (1999) Diabetes Care , vol.22 , pp. 141-146
    • Ehrmann, D.A.1    Barnes, R.B.2    Rosenfield, R.L.3    Cavaghan, M.K.4    Imperial, J.5
  • 61
    • 0033031506 scopus 로고    scopus 로고
    • Effects of regular walking on cardiovascular risk factors and body composition in normoglycemic women and women with type 2 diabetes
    • Walker KZ, Piers LS, Putt RS, Jones JA, O'Dea K. Effects of regular walking on cardiovascular risk factors and body composition in normoglycemic women and women with type 2 diabetes. Diabetes Care. 1999;22:555-561.
    • (1999) Diabetes Care , vol.22 , pp. 555-561
    • Walker, K.Z.1    Piers, L.S.2    Putt, R.S.3    Jones, J.A.4    O'Dea, K.5
  • 62
    • 0034152946 scopus 로고    scopus 로고
    • Study of plasma hormones and lipids in healthy elderly Thais compared to patients with chronic diseases: Diabetes mellitus, essential hypertension and coronary heart disease
    • Chearskul S, Charoenlarp K, Thongtang V, Nitiyanant W. Study of plasma hormones and lipids in healthy elderly Thais compared to patients with chronic diseases: diabetes mellitus, essential hypertension and coronary heart disease. J Med Assoc Thai. 2000;83:266-277.
    • (2000) J Med Assoc Thai , vol.83 , pp. 266-277
    • Chearskul, S.1    Charoenlarp, K.2    Thongtang, V.3    Nitiyanant, W.4
  • 63
    • 0033957394 scopus 로고    scopus 로고
    • Association of hyperandrogenemia and hyperestrogenemia with type 2 diabetes in Hispanic postmenopausal women
    • Phillips GB, Tuck CH, Jing TY, et al. Association of hyperandrogenemia and hyperestrogenemia with type 2 diabetes in Hispanic postmenopausal women. Diabetes Care. 2000;23:74-79.
    • (2000) Diabetes Care , vol.23 , pp. 74-79
    • Phillips, G.B.1    Tuck, C.H.2    Jing, T.Y.3
  • 64
    • 0033673865 scopus 로고    scopus 로고
    • Association of increased C-peptide serum levels and testosterone in type 2 diabetes
    • Zietz B, Cuk A, Hugl S, et al. Association of increased C-peptide serum levels and testosterone in type 2 diabetes. Eur J Intern Med. 2000;11:322-328.
    • (2000) Eur J Intern Med , vol.11 , pp. 322-328
    • Zietz, B.1    Cuk, A.2    Hugl, S.3
  • 65
    • 0035980374 scopus 로고    scopus 로고
    • Association of acanthosis nigricans with risk of diabetes mellitus, and hormonal disturbances in Arabian females: Case-control study
    • Bener A, Lestringant GG, Townsend A, Al-Mulla HM. Association of acanthosis nigricans with risk of diabetes mellitus, and hormonal disturbances in Arabian females: case-control study. Maturitas. 2001;40:53-59.
    • (2001) Maturitas , vol.40 , pp. 53-59
    • Bener, A.1    Lestringant, G.G.2    Townsend, A.3    Al-Mulla, H.M.4
  • 66
    • 0034914348 scopus 로고    scopus 로고
    • Lactate and glycerol release from adipose tissue in lean, obese, and diabetic women from South Africa
    • van der Merwe MT, Schlaphoff GP, Crowther NJ, et al. Lactate and glycerol release from adipose tissue in lean, obese, and diabetic women from South Africa. J Clin Endocrinol Metab. 2001;86:3296-3303.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3296-3303
    • Van Der Merwe, M.T.1    Schlaphoff, G.P.2    Crowther, N.J.3
  • 67
    • 2342523374 scopus 로고    scopus 로고
    • Partial androgen deficiency in aging type 2 diabetic men and its relationship to glycemic control
    • Corrales JJ, Burgo RM, Garca-Berrocal B, et al. Partial androgen deficiency in aging type 2 diabetic men and its relationship to glycemic control. Metabolism. 2004;53:666-672.
    • (2004) Metabolism , vol.53 , pp. 666-672
    • Corrales, J.J.1    Burgo, R.M.2    Garca-Berrocal, B.3
  • 68
    • 1042280186 scopus 로고    scopus 로고
    • The biological variation of sex hormone-binding globulin in type 2 diabetes: Implications for sex hormone-binding globulin as a surrogate marker of insulin resistance
    • Jayagopal V, Kilpatrick ES, Jennings PE, Holding S, Hepburn DA, Atkin SL. The biological variation of sex hormone-binding globulin in type 2 diabetes: implications for sex hormone-binding globulin as a surrogate marker of insulin resistance. Diabetes Care. 2004;27:278-280.
    • (2004) Diabetes Care , vol.27 , pp. 278-280
    • Jayagopal, V.1    Kilpatrick, E.S.2    Jennings, P.E.3    Holding, S.4    Hepburn, D.A.5    Atkin, S.L.6
  • 69
    • 1842507028 scopus 로고    scopus 로고
    • The associations of endogenous testosterone and sex hormone-binding globulin with glycosylated hemoglobin levels, in community dwelling men: The Tromso Study
    • Svartberg J, Jenssen T, Sundsfjord J, Jorde R. The associations of endogenous testosterone and sex hormone-binding globulin with glycosylated hemoglobin levels, in community dwelling men: the Tromso Study. Diabetes Metab. 2004;30:29-34.
    • (2004) Diabetes Metab , vol.30 , pp. 29-34
    • Svartberg, J.1    Jenssen, T.2    Sundsfjord, J.3    Jorde, R.4
  • 70
    • 15944371521 scopus 로고    scopus 로고
    • Sex hormone-binding globulin and insulin-like growth factor-binding protein-1 as indicators of metabolic syndrome, cardiovascular risk, and mortality in elderly men
    • Kalme T, Seppala M, Qiao Q, et al. Sex hormone-binding globulin and insulin-like growth factor-binding protein-1 as indicators of metabolic syndrome, cardiovascular risk, and mortality in elderly men. J Clin Endocrinol Metab. 2005;90:1550-1556.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1550-1556
    • Kalme, T.1    Seppala, M.2    Qiao, Q.3
  • 71
    • 85047685406 scopus 로고    scopus 로고
    • An extraordinarily inaccurate assay for free testosterone is still with us
    • Rosner W. An extraordinarily inaccurate assay for free testosterone is still with us. J Clin Endocrinol Metab. 2001;86:2903.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2903
    • Rosner, W.1
  • 72
    • 0031154168 scopus 로고    scopus 로고
    • Errors in the measurement of plasma free testosterone
    • Rosner W. Errors in the measurement of plasma free testosterone. J Clin Endocrinol Metab. 1997;82:2014-2015.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2014-2015
    • Rosner, W.1
  • 73
    • 0033305020 scopus 로고    scopus 로고
    • A critical evaluation of simple methods for the estimation of free testosterone in serum
    • Vermeulen A, Verdonck L, Kaufman JM. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab. 1999;84:3666-3672.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3666-3672
    • Vermeulen, A.1    Verdonck, L.2    Kaufman, J.M.3
  • 74
    • 0023626101 scopus 로고
    • Total testosterone, free-androgen index, calculated free testosterone, and free testosterone by analog RIA compared in hirsute women and in otherwise-normal women with altered binding of sex-hormone-binding globulin
    • Wilke TJ, Utley DJ. Total testosterone, free-androgen index, calculated free testosterone, and free testosterone by analog RIA compared in hirsute women and in otherwise-normal women with altered binding of sex-hormone-binding globulin. Clin Chem. 1987;33:1372-1375.
    • (1987) Clin Chem , vol.33 , pp. 1372-1375
    • Wilke, T.J.1    Utley, D.J.2
  • 76
    • 1442327861 scopus 로고    scopus 로고
    • Measurement of free testosterone in normal women and women with androgen deficiency: Comparison of methods
    • Miller KK, Rosner W, Lee H, et al. Measurement of free testosterone in normal women and women with androgen deficiency: comparison of methods. J Clin Endocrinol Metab. 2004;89:525-533.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 525-533
    • Miller, K.K.1    Rosner, W.2    Lee, H.3
  • 77
    • 1442327856 scopus 로고    scopus 로고
    • Measurement of total serum testosterone in adult men: Comparison of current laboratory methods versus liquid chromatography-tandem mass spectrometry
    • Wang C, Catlin DH, Demers LM, Starcevic B, Swerdloff RS. Measurement of total serum testosterone in adult men: comparison of current laboratory methods versus liquid chromatography-tandem mass spectrometry. J Clin Endocrinol Metab. 2004;89:534-543.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 534-543
    • Wang, C.1    Catlin, D.H.2    Demers, L.M.3    Starcevic, B.4    Swerdloff, R.S.5
  • 79
    • 0037186429 scopus 로고    scopus 로고
    • Advanced methods in meta-analysis: Multivariate approach and meta-regression
    • van Houwelingen HC, Arends LR, Stijnen T. Advanced methods in meta-analysis: multivariate approach and meta-regression. Stat Med. 2002;21:589-624.
    • (2002) Stat Med , vol.21 , pp. 589-624
    • Houwelingen, H.C.1    Arends, L.R.2    Stijnen, T.3
  • 81
    • 4544388002 scopus 로고    scopus 로고
    • Glucose and insulin components of the metabolic syndrome are associated with hyperandrogenism in postmenopausal women: The Atherosclerosis Risk in Communities study
    • Golden SH, Ding J, Szklo M, Schmidt MI, Duncan BB, Dobs A. Glucose and insulin components of the metabolic syndrome are associated with hyperandrogenism in postmenopausal women: the Atherosclerosis Risk In Communities study. Am J Epidemiol. 2004;160:540-548.
    • (2004) Am J Epidemiol , vol.160 , pp. 540-548
    • Golden, S.H.1    Ding, J.2    Szklo, M.3    Schmidt, M.I.4    Duncan, B.B.5    Dobs, A.6
  • 82
    • 0035092235 scopus 로고    scopus 로고
    • Relationship of the metabolic syndrome and obesity to polycystic ovary syndrome: A controlled, population-based study
    • Korhonen S, Hippelainen M, Niskanen L, Vanhala M, Saarikoski S. Relationship of the metabolic syndrome and obesity to polycystic ovary syndrome: a controlled, population-based study. Am J Obstet Gynecol. 2001;184:289-296.
    • (2001) Am J Obstet Gynecol , vol.184 , pp. 289-296
    • Korhonen, S.1    Hippelainen, M.2    Niskanen, L.3    Vanhala, M.4    Saarikoski, S.5
  • 84
    • 0026761599 scopus 로고
    • Lower endogenous androgens predict central adiposity in men
    • Khaw KT, Barrett-Connor E. Lower endogenous androgens predict central adiposity in men. Ann Epidemiol. 1992;2:675-682.
    • (1992) Ann Epidemiol , vol.2 , pp. 675-682
    • Khaw, K.T.1    Barrett-Connor, E.2
  • 85
    • 0034128215 scopus 로고    scopus 로고
    • Low serum testosterone level as a predictor of increased visceral fat in Japanese-American men
    • Tsai EC, Boyko EJ, Leonetti DL, Fujimoto WY. Low serum testosterone level as a predictor of increased visceral fat in Japanese-American men. Int J Obes Relat Metab Disord. 2000;24:485-491.
    • (2000) Int J Obes Relat Metab Disord , vol.24 , pp. 485-491
    • Tsai, E.C.1    Boyko, E.J.2    Leonetti, D.L.3    Fujimoto, W.Y.4
  • 86
    • 0034847215 scopus 로고    scopus 로고
    • The effects of induced hypogonadism on arterial stiffness, body composition, and metabolic parameters in males with prostate cancer
    • Smith JC, Bennett S, Evans LM, et al. The effects of induced hypogonadism on arterial stiffness, body composition, and metabolic parameters in males with prostate cancer. J Clin Endocrinol Metab. 2001;86:4261-4267.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4261-4267
    • Smith, J.C.1    Bennett, S.2    Evans, L.M.3
  • 87
    • 33646029746 scopus 로고    scopus 로고
    • Insulin sensitivity during combined androgen blockade for prostate cancer
    • published online ahead of print January 24, 2006 doi:10.1210/jc2005-2507
    • Smith MR, Lee H, Nathan DM. Insulin sensitivity during combined androgen blockade for prostate cancer [published online ahead of print January 24, 2006]. J Clin Endocrinol Metab. doi:10.1210/jc2005-2507.
    • J Clin Endocrinol Metab
    • Smith, M.R.1    Lee, H.2    Nathan, D.M.3
  • 88
    • 0033307232 scopus 로고    scopus 로고
    • Effect of testosterone treatment on body composition and muscle strength in men over 65 years of age
    • Snyder PJ, Peachey H, Hannoush P, et al. Effect of testosterone treatment on body composition and muscle strength in men over 65 years of age. J Clin Endocrinol Metab. 1999;84:2647-2653.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 2647-2653
    • Snyder, P.J.1    Peachey, H.2    Hannoush, P.3
  • 90
    • 0034456450 scopus 로고    scopus 로고
    • Transdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men
    • Wang C, Swerdloff RS, Iranmanesh A, et al. Transdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men. J Clin Endocrinol Metab. 2000;85:2839-2853.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2839-2853
    • Wang, C.1    Swerdloff, R.S.2    Iranmanesh, A.3
  • 91
    • 0026399706 scopus 로고
    • Effect of testosterone on abdominal adipose tissue in men
    • Rebuffe-Scrive M, Marin P, Bjorntorp P. Effect of testosterone on abdominal adipose tissue in men. Int J Obes. 1991;15:791-795.
    • (1991) Int J Obes , vol.15 , pp. 791-795
    • Rebuffe-Scrive, M.1    Marin, P.2    Bjorntorp, P.3
  • 92
    • 0038823605 scopus 로고    scopus 로고
    • Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiency
    • Boyanov MA, Boneva Z, Christov VG. Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiency. Aging Male. 2003;6:1-7.
    • (2003) Aging Male , vol.6 , pp. 1-7
    • Boyanov, M.A.1    Boneva, Z.2    Christov, V.G.3
  • 93
    • 0041883279 scopus 로고    scopus 로고
    • The short-term effects of high-dose testosterone on sleep, breathing, and function in older men
    • Liu PY, Yee B, Wishart SM, et al. The short-term effects of high-dose testosterone on sleep, breathing, and function in older men. J Clin Endocrinol Metab. 2003;88:3605-3613.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 3605-3613
    • Liu, P.Y.1    Yee, B.2    Wishart, S.M.3
  • 94
    • 0000405022 scopus 로고
    • Testosterone and regional fat distribution
    • Marin P. Testosterone and regional fat distribution. Obes Res. 1995;3(suppl 4):609S-612S.
    • (1995) Obes Res , vol.3 , Issue.4 SUPPL.
    • Marin, P.1
  • 95
    • 0141564597 scopus 로고    scopus 로고
    • Testosterone replacement therapy restores normal ghrelin in hypogonadal men
    • Pagotto U, Gambineri A, Pelusi C, et al. Testosterone replacement therapy restores normal ghrelin in hypogonadal men. J Clin Endocrinol Metab. 2003;88:4139-4143.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4139-4143
    • Pagotto, U.1    Gambineri, A.2    Pelusi, C.3
  • 96
    • 0030010984 scopus 로고    scopus 로고
    • Exogenous androgens influence body composition and regional body fat distribution in obese postmenopausal women - A clinical research center study
    • Lovejoy JC, Bray GA, Bourgeois MO, et al. Exogenous androgens influence body composition and regional body fat distribution in obese postmenopausal women - a clinical research center study. J Clin Endocrinol Metab. 1996;81:2198-2203.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2198-2203
    • Lovejoy, J.C.1    Bray, G.A.2    Bourgeois, M.O.3
  • 97
    • 0142025214 scopus 로고    scopus 로고
    • Antiandrogen treatment increases circulating ghrelin levels in obese women with polycystic ovary syndrome
    • Gambineri A, Pagotto U, Tschop M, et al. Antiandrogen treatment increases circulating ghrelin levels in obese women with polycystic ovary syndrome. J Endocrinol Invest. 2003;26:629-634.
    • (2003) J Endocrinol Invest , vol.26 , pp. 629-634
    • Gambineri, A.1    Pagotto, U.2    Tschop, M.3
  • 98
    • 0025797497 scopus 로고
    • Fasting plasma glucose levels and endogenous androgens in nondiabetic postmenopausal women
    • Lond
    • Khaw KT, Barrett-Connor E. Fasting plasma glucose levels and endogenous androgens in nondiabetic postmenopausal women. Clin Sci (Lond). 1991;80:199-203.
    • (1991) Clin Sci , vol.80 , pp. 199-203
    • Khaw, K.T.1    Barrett-Connor, E.2
  • 99
    • 0027459061 scopus 로고
    • Relationship between serum sex hormones and the glucose-insulin-lipid defect in men with obesity
    • Phillips GB. Relationship between serum sex hormones and the glucose-insulin-lipid defect in men with obesity. Metabolism. 1993;42:116-120.
    • (1993) Metabolism , vol.42 , pp. 116-120
    • Phillips, G.B.1
  • 100
    • 0036078815 scopus 로고    scopus 로고
    • Additive effects of insulin-sensitizing and anti-androgen treatment in young, nonobese women with hyperinsulinism, hyperandrogenism, dyslipidemia, and anovulation
    • Ibanez L, Valls C, Ferrer A, Ong K, Dunger DB, De Zegher F. Additive effects of insulin-sensitizing and anti-androgen treatment in young, nonobese women with hyperinsulinism, hyperandrogenism, dyslipidemia, and anovulation. J Clin Endocrinol Metab. 2002;87:2870-2874.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2870-2874
    • Ibanez, L.1    Valls, C.2    Ferrer, A.3    Ong, K.4    Dunger, D.B.5    De Zegher, F.6
  • 101
    • 0029926833 scopus 로고    scopus 로고
    • Mechanisms behind insulin resistance in rat skeletal muscle after oophorectomy and additional testosterone treatment
    • Rincon J, Holmang A, Wahlstrom EO, et al. Mechanisms behind insulin resistance in rat skeletal muscle after oophorectomy and additional testosterone treatment. Diabetes. 1996;45:615-621.
    • (1996) Diabetes , vol.45 , pp. 615-621
    • Rincon, J.1    Holmang, A.2    Wahlstrom, E.O.3
  • 102
    • 20044369200 scopus 로고    scopus 로고
    • Insulin and leptin resistance with hyperleptinemia in mice lacking androgen receptor
    • Lin HY, Xu Q, Yeh S, Wang RS, Sparks JD, Chang C. Insulin and leptin resistance with hyperleptinemia in mice lacking androgen receptor. Diabetes. 2005;54:1717-1725.
    • (2005) Diabetes , vol.54 , pp. 1717-1725
    • Lin, H.Y.1    Xu, Q.2    Yeh, S.3    Wang, R.S.4    Sparks, J.D.5    Chang, C.6
  • 103
    • 0029972402 scopus 로고    scopus 로고
    • The regulation of adipose tissue distribution in humans
    • Bjorntorp P. The regulation of adipose tissue distribution in humans. Int J Obes Relat Metab Disord. 1996;20:291-302.
    • (1996) Int J Obes Relat Metab Disord , vol.20 , pp. 291-302
    • Bjorntorp, P.1
  • 104
    • 0028797188 scopus 로고
    • Assimilation and mobilization of triglycerides in subcutaneous abdominal and femoral adipose tissue in vivo in men: Effects of androgens
    • Marin P, Oden B, Bjorntorp P. Assimilation and mobilization of triglycerides in subcutaneous abdominal and femoral adipose tissue in vivo in men: effects of androgens. J Clin Endocrinol Metab. 1995;80:239-243.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 239-243
    • Marin, P.1    Oden, B.2    Bjorntorp, P.3
  • 105
    • 0031034361 scopus 로고    scopus 로고
    • Testosterone replacement increases fat-free mass and muscle size in hypogonadal men
    • Bhasin S, Storer TW, Berman N, et al. Testosterone replacement increases fat-free mass and muscle size in hypogonadal men. J Clin Endocrinol Metab. 1997;82:407-413.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 407-413
    • Bhasin, S.1    Storer, T.W.2    Berman, N.3
  • 106
    • 0033983480 scopus 로고    scopus 로고
    • Testosterone replacement and resistance exercise in HIV-infected men with weight loss and low testosterone levels
    • Bhasin S, Storer TW, Javanbakht M, et al. Testosterone replacement and resistance exercise in HIV-infected men with weight loss and low testosterone levels. JAMA. 2000;283:763-770.
    • (2000) JAMA , vol.283 , pp. 763-770
    • Bhasin, S.1    Storer, T.W.2    Javanbakht, M.3
  • 107
    • 0026742650 scopus 로고
    • Effects of testosterone supplementation in the aging male
    • Tenover JS. Effects of testosterone supplementation in the aging male. J Clin Endocrinol Metab. 1992;75:1092-1098.
    • (1992) J Clin Endocrinol Metab , vol.75 , pp. 1092-1098
    • Tenover, J.S.1
  • 108
    • 17744390362 scopus 로고    scopus 로고
    • Effects of testosterone replacement in hypogonadal men
    • Snyder PJ, Peachey H, Berlin JA, et al. Effects of testosterone replacement in hypogonadal men. J Clin Endocrinol Metab. 2000;85:2670-2677.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2670-2677
    • Snyder, P.J.1    Peachey, H.2    Berlin, J.A.3
  • 109
    • 8944233864 scopus 로고    scopus 로고
    • The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men
    • Bhasin S, Storer TW, Berman N, et al. The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men. N Engl J Med. 1996;335:1-7.
    • (1996) N Engl J Med , vol.335 , pp. 1-7
    • Bhasin, S.1    Storer, T.W.2    Berman, N.3
  • 110
    • 3242667701 scopus 로고    scopus 로고
    • The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men
    • Malkin CJ, Pugh PJ, Jones RD, Kapoor D, Channer KS, Jones TH. The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men. J Clin Endocrinol Metab. 2004;89:3313-3318.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 3313-3318
    • Malkin, C.J.1    Pugh, P.J.2    Jones, R.D.3    Kapoor, D.4    Channer, K.S.5    Jones, T.H.6
  • 111
    • 3242717140 scopus 로고    scopus 로고
    • Testosterone replacement in hypogonadal men with angina improves ischaemic threshold and quality of life
    • Malkin CJ, Pugh PJ, Morris PD, et al. Testosterone replacement in hypogonadal men with angina improves ischaemic threshold and quality of life. Heart. 2004;90:871-876.
    • (2004) Heart , vol.90 , pp. 871-876
    • Malkin, C.J.1    Pugh, P.J.2    Morris, P.D.3
  • 112
    • 0028931724 scopus 로고
    • Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
    • Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest. 1995;95:2409-2415.
    • (1995) J Clin Invest , vol.95 , pp. 2409-2415
    • Hotamisligil, G.S.1    Arner, P.2    Caro, J.F.3    Atkinson, R.L.4    Spiegelman, B.M.5
  • 113
    • 0031793622 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha causes insulin receptor substrate-2-mediated insulin resistance and inhibits insulin-induced adipogenesis in fetal brown adipocytes
    • Valverde AM, Teruel T, Navarro P, Benito M, Lorenzo M. Tumor necrosis factor-alpha causes insulin receptor substrate-2-mediated insulin resistance and inhibits insulin-induced adipogenesis in fetal brown adipocytes. Endocrinology. 1998;139:1229-1238.
    • (1998) Endocrinology , vol.139 , pp. 1229-1238
    • Valverde, A.M.1    Teruel, T.2    Navarro, P.3    Benito, M.4    Lorenzo, M.5
  • 114
    • 0030028606 scopus 로고    scopus 로고
    • The expression of TNF alpha by human muscle: Relationship to insulin resistance
    • Saghizadeh M, Ong JM, Garvey WT, Henry RR, Kern PA. The expression of TNF alpha by human muscle: relationship to insulin resistance. J Clin Invest. 1996;97:1111-1116.
    • (1996) J Clin Invest , vol.97 , pp. 1111-1116
    • Saghizadeh, M.1    Ong, J.M.2    Garvey, W.T.3    Henry, R.R.4    Kern, P.A.5
  • 115
    • 0345700727 scopus 로고    scopus 로고
    • Inflammatory cytokines and the risk to develop type 2 diabetes: Results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study
    • Spranger J, Kroke A, Mohlig M, et al. Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Diabetes. 2003;52:812-817.
    • (2003) Diabetes , vol.52 , pp. 812-817
    • Spranger, J.1    Kroke, A.2    Mohlig, M.3
  • 116
    • 1442301080 scopus 로고    scopus 로고
    • Inflammatory markers and risk of developing type 2 diabetes in women
    • Hu FB, Meigs JB, Li TY, Rifai N, Manson JE. Inflammatory markers and risk of developing type 2 diabetes in women. Diabetes. 2004;53:693-700.
    • (2004) Diabetes , vol.53 , pp. 693-700
    • Hu, F.B.1    Meigs, J.B.2    Li, T.Y.3    Rifai, N.4    Manson, J.E.5
  • 117
    • 3543083877 scopus 로고    scopus 로고
    • Gender difference in the non-specific and specific immune response in humans
    • Bouman A, Schipper M, Heineman MJ, Faas MM. Gender difference in the non-specific and specific immune response in humans. Am J Reprod Immunol. 2004;52:19-26.
    • (2004) Am J Reprod Immunol , vol.52 , pp. 19-26
    • Bouman, A.1    Schipper, M.2    Heineman, M.J.3    Faas, M.M.4
  • 118
    • 0142155094 scopus 로고    scopus 로고
    • The effect of age and gender on cytokine production by human peripheral blood mononuclear cells and markers of bone metabolism
    • Pietschmann P, Gollob E, Brosch S, et al. The effect of age and gender on cytokine production by human peripheral blood mononuclear cells and markers of bone metabolism. Exp Gerontol. 2003;38:1119-1127.
    • (2003) Exp Gerontol , vol.38 , pp. 1119-1127
    • Pietschmann, P.1    Gollob, E.2    Brosch, S.3
  • 119
    • 0019759637 scopus 로고
    • Transport of steroid hormones: Binding of 21 endogenous steroids to both testosterone-binding globulin and corticosteroid-binding globulin in human plasma
    • Dunn JF, Nisula BC, Rodbard D. Transport of steroid hormones: binding of 21 endogenous steroids to both testosterone-binding globulin and corticosteroid-binding globulin in human plasma. J Clin Endocrinol Metab. 1981;53:58-68.
    • (1981) J Clin Endocrinol Metab , vol.53 , pp. 58-68
    • Dunn, J.F.1    Nisula, B.C.2    Rodbard, D.3
  • 120
    • 0038645220 scopus 로고    scopus 로고
    • Differing effects of oral and transdermal hormone replacement therapy on cardiovascular risk factors in healthy postmenopausal women
    • Strandberg TE, Ylikorkala O, Tikkanen MJ. Differing effects of oral and transdermal hormone replacement therapy on cardiovascular risk factors in healthy postmenopausal women. Am J Cardiol. 2003;92:212-214.
    • (2003) Am J Cardiol , vol.92 , pp. 212-214
    • Strandberg, T.E.1    Ylikorkala, O.2    Tikkanen, M.J.3
  • 121
    • 0035067690 scopus 로고    scopus 로고
    • Effects of oral and transdermal estrogen replacement therapy on markers of coagulation, fibrinolysis, inflammation and serum lipids and lipoproteins in postmenopausal women
    • Vehkavaara S, Silveira A, Hakala-Ala-Pietila T, et al. Effects of oral and transdermal estrogen replacement therapy on markers of coagulation, fibrinolysis, inflammation and serum lipids and lipoproteins in postmenopausal women. Thromb Haemost. 2001;85:619-625.
    • (2001) Thromb Haemost , vol.85 , pp. 619-625
    • Vehkavaara, S.1    Silveira, A.2    Hakala-Ala-Pietila, T.3
  • 122
    • 0032168320 scopus 로고    scopus 로고
    • The route of estrogen replacement therapy confers divergent effects on substrate oxidation and body composition in postmenopausal women
    • O'Sullivan AJ, Crampton LJ, Freund J, Ho KK. The route of estrogen replacement therapy confers divergent effects on substrate oxidation and body composition in postmenopausal women. J Clin Invest. 1998;102:1035-1040.
    • (1998) J Clin Invest , vol.102 , pp. 1035-1040
    • O'Sullivan, A.J.1    Crampton, L.J.2    Freund, J.3    Ho, K.K.4
  • 123
    • 24144439116 scopus 로고    scopus 로고
    • Role of endocytosis in cellular uptake of sex steroids
    • Hammes A, Andreassen TK, Spoelgen R, et al. Role of endocytosis in cellular uptake of sex steroids. Cell. 2005;122:751-762.
    • (2005) Cell , vol.122 , pp. 751-762
    • Hammes, A.1    Andreassen, T.K.2    Spoelgen, R.3
  • 124
    • 0032977457 scopus 로고    scopus 로고
    • Sex hormone-binding globulin mediates steroid hormone signal transduction at the plasma membrane
    • Rosner W, Hryb DJ, Khan MS, Nakhla AM, Romas NA. Sex hormone-binding globulin mediates steroid hormone signal transduction at the plasma membrane. J Steroid Biochem Mol Biol. 1999;69:481-485.
    • (1999) J Steroid Biochem Mol Biol , vol.69 , pp. 481-485
    • Rosner, W.1    Hryb, D.J.2    Khan, M.S.3    Nakhla, A.M.4    Romas, N.A.5
  • 125
    • 0020417830 scopus 로고
    • Calculation of free and bound fractions of testosterone and estradiol-17 beta to human plasma proteins at body temperature
    • Sodergard R, Backstrom T, Shanbhag V, Carstensen H. Calculation of free and bound fractions of testosterone and estradiol-17 beta to human plasma proteins at body temperature. J Steroid Biochem. 1982;16:801-810.
    • (1982) J Steroid Biochem , vol.16 , pp. 801-810
    • Sodergard, R.1    Backstrom, T.2    Shanbhag, V.3    Carstensen, H.4
  • 126
    • 0347993723 scopus 로고    scopus 로고
    • Free estradiol and breast cancer risk in postmenopausal women: Comparison of measured and calculated values
    • Endogenous Hormones and Breast Cancer Collaborative Group. Free estradiol and breast cancer risk in postmenopausal women: comparison of measured and calculated values. Cancer Epidemiol Biomarkers Prev. 2003;12:1457-1461.
    • (2003) Cancer Epidemiol Biomarkers Prev , vol.12 , pp. 1457-1461
  • 127
    • 0036800654 scopus 로고    scopus 로고
    • Validity of free testosterone and free estradiol determinations in serum samples from postmenopausal women by theoretical calculations
    • Rinaldi S, Geay A, Dechaud H, et al. Validity of free testosterone and free estradiol determinations in serum samples from postmenopausal women by theoretical calculations. Cancer Epidemiol Biomarkers Prev. 2002;11:1065-1071.
    • (2002) Cancer Epidemiol Biomarkers Prev , vol.11 , pp. 1065-1071
    • Rinaldi, S.1    Geay, A.2    Dechaud, H.3
  • 128
    • 15444366255 scopus 로고    scopus 로고
    • Polycystic ovary syndrome
    • Ehrmann DA. Polycystic ovary syndrome. N Engl J Med. 2005;352:1223-1236.
    • (2005) N Engl J Med , vol.352 , pp. 1223-1236
    • Ehrmann, D.A.1
  • 129
    • 0029969585 scopus 로고    scopus 로고
    • Sex hormone-binding protein, hyperinsulinemia, insulin resistance and noninsulin-dependent diabetes
    • Haffner SM. Sex hormone-binding protein, hyperinsulinemia, insulin resistance and noninsulin-dependent diabetes. Horm Res. 1996;45:233-237.
    • (1996) Horm Res , vol.45 , pp. 233-237
    • Haffner, S.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.