Bacillus anthracis inosine 5′-monophosphate dehydrogenase in action: The first bacterial series of structures of phosphate ion-, substrate-, and product-bound complexes

Biochemistry

Volumn 51, Issue 31, 2012, Pages 6148-6163

  Makowska Grzyska, Magdalena ^a   Kim, Youngchang ^a,b   Wu, Ruiying ^b   Wilton, Rosemarie ^b   Gollapalli, Deviprasad R ^c   Wang, Ximi K ^c   Zhang, Rongguang ^b   Jedrzejczak, Robert ^b   MacK, Jamey C ^b   Maltseva, Natalia ^a   Mulligan, Rory ^a   Binkowski, T Andrew ^a,b   Gornicki, Piotr ^a   Kuhn, Misty L ^d   Anderson, Wayne F ^d   Hedstrom, Lizbeth ^c   Joachimiak, Andrzej ^a,b  

^a UNIVERSITY OF CHICAGO   (United States)

^b ARGONNE NATIONAL LABORATORY   (United States)

^c BRANDEIS UNIVERSITY   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ANTHRACIS; ANTI-VIRAL DRUGS; ANTIBIOTIC ACTIVITY; BACILLUS ANTHRACIS; BIOSYNTHETIC PATHWAY; CAMPYLOBACTER JEJUNI; CLINICAL APPLICATION; CLOSTRIDIUM PERFRINGENS; CRYPTOSPORIDIUM PARVUM; ENZYMATIC REACTION; IMMUNOSUPPRESSANTS; INHIBITORY EFFECT; INOSINE; MONOPHOSPHATES; MYCOPHENOLIC ACIDS; PROKARYOTIC ENZYMES; PURINE NUCLEOTIDES; VIBRIO CHOLERAE; XANTHOSINE;

BACTERIA;

ENZYMES;

A 110; ARGININE; C 91; INOSINATE DEHYDROGENASE; INOSINATE DEHYDROGENASE INHIBITOR; INOSINE PHOSPHATE; MYCOPHENOLIC ACID; PHOSPHATE; TYROSINE; UNCLASSIFIED DRUG; XANTHOSINE; XANTHOSINE 5 PHOSPHATE;

ARTICLE; BACILLUS ANTHRACIS; CAMPYLOBACTER JEJUNI; CLOSTRIDIUM PERFRINGENS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; IC 50; NONHUMAN; PRIORITY JOURNAL; VIBRIO CHOLERAE;

AMINO ACID SEQUENCE; APOENZYMES; BACILLUS ANTHRACIS; BENZIMIDAZOLES; CATALYTIC DOMAIN; ENZYME INHIBITORS; IMP DEHYDROGENASE; INOSINE MONOPHOSPHATE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOPHENOLIC ACID; NAD; PROTEIN BINDING; RIBONUCLEOTIDES; TRIAZOLES;

BACILLUS ANTHRACIS; BACTERIA (MICROORGANISMS); CAMPYLOBACTER JEJUNI; CLOSTRIDIUM PERFRINGENS; CRYPTOSPORIDIUM PARVUM; PROKARYOTA; VIBRIO CHOLERAE;

EID: 84864673403     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300511w     Document Type: Article

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