The antibiotic potential of prokaryotic IMP dehydrogenase inhibitors

Current Medicinal Chemistry

Volumn 18, Issue 13, 2011, Pages 1909-1918

  Hedstrom, L ^a   Liechti, G ^b   Goldberg, J B ^b   Gollapalli, D R ^a  

^a BRANDEIS UNIVERSITY   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

Antibacterial; Cryptosporidium parvum; Guanine nucleotide biosynthesis; Helicobacter pylori; IMPDH; Inosine 5 monophosphate dehydrogenase; Mycobacterium tuberculosis; Select agents

Indexed keywords

ANTIBIOTIC AGENT; GUANOSINE PHOSPHATE; INOSINATE DEHYDROGENASE; INOSINATE DEHYDROGENASE INHIBITOR;

ANTIBACTERIAL ACTIVITY; ARTICLE; CRYPTOSPORIDIUM PARVUM; DRUG SENSITIVITY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME STRUCTURE; HELICOBACTER PYLORI; HUMAN; IC 50; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIA; DRUG RESISTANCE, BACTERIAL; ENZYME INHIBITORS; HUMANS; IMP DEHYDROGENASE; SPECIES SPECIFICITY;

EID: 79957938394     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986711795590129     Document Type: Article

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