A screening pipeline for antiparasitic agents targeting Cryptosporidium inosine monophosphate dehydrogenase

PLoS Neglected Tropical Diseases

Volumn 4, Issue 8, 2010, Pages

  Sharling, Lisa ^a   Liu, Xiaoping ^a   Gollapalli, Deviprasad R ^b   Maurya, Sushil K ^b   Hedstrom, Lizbeth ^b   Striepen, Boris ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3 TRIAZOLE DERIVATIVE; INOSINATE DEHYDROGENASE; INOSINATE DEHYDROGENASE INHIBITOR; ANTIPROTOZOAL AGENT; ENZYME INHIBITOR; TRIAZOLE DERIVATIVE;

ANTIPROTOZOAL ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CRYPTOSPORIDIUM PARVUM; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG TARGETING; FLUORESCENCE ANALYSIS; GENETIC ENGINEERING; HIGH THROUGHPUT SCREENING; HOST CELL; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; NONHUMAN; TOXOPLASMA GONDII; VALIDATION STUDY; AUTOMATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETICS; IMAGE PROCESSING; ISOLATION AND PURIFICATION; METHODOLOGY; STAINING; TOXOPLASMA;

ANTIPROTOZOAL AGENTS; AUTOMATION; CRYPTOSPORIDIUM PARVUM; DRUG EVALUATION, PRECLINICAL; ENZYME INHIBITORS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMP DEHYDROGENASE; STAINING AND LABELING; TOXOPLASMA; TRIAZOLES;

EID: 78149262280     PISSN: None     EISSN: None     Source Type: Journal    
DOI: 10.1371/journal.pntd.0000794     Document Type: Article

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